PL2591125T3 - Strategie sekwencjonowania będącego przedmiotem zainteresowania genomowego regionu 3-d - Google Patents

Strategie sekwencjonowania będącego przedmiotem zainteresowania genomowego regionu 3-d

Info

Publication number
PL2591125T3
PL2591125T3 PL11736190T PL11736190T PL2591125T3 PL 2591125 T3 PL2591125 T3 PL 2591125T3 PL 11736190 T PL11736190 T PL 11736190T PL 11736190 T PL11736190 T PL 11736190T PL 2591125 T3 PL2591125 T3 PL 2591125T3
Authority
PL
Poland
Prior art keywords
genomic region
sequencing strategies
interest
interest sequencing
strategies
Prior art date
Application number
PL11736190T
Other languages
English (en)
Polish (pl)
Inventor
Max Jan van Min
Wouter Leonard De Laat
Original Assignee
Cergentis B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cergentis B.V. filed Critical Cergentis B.V.
Publication of PL2591125T3 publication Critical patent/PL2591125T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855Ligating adaptors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00Reaction characterised by the enzymatic activity
    • C12Q2521/30Phosphoric diester hydrolysing, i.e. nuclease
    • C12Q2521/301Endonuclease
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00Reaction characterised by the enzymatic activity
    • C12Q2521/50Other enzymatic activities
    • C12Q2521/501Ligase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00Reactions characterised by treatment of reaction samples
    • C12Q2523/10Characterised by chemical treatment
    • C12Q2523/101Crosslinking agents, e.g. psoralen
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00Reactions characterised by treatment of reaction samples
    • C12Q2523/10Characterised by chemical treatment
    • C12Q2523/107Chemical cleaving agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/30Oligonucleotides characterised by their secondary structure
    • C12Q2525/307Circular oligonucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • General Chemical & Material Sciences (AREA)
PL11736190T 2010-07-09 2011-07-08 Strategie sekwencjonowania będącego przedmiotem zainteresowania genomowego regionu 3-d PL2591125T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36277810P 2010-07-09 2010-07-09
EP11736190.7A EP2591125B1 (en) 2010-07-09 2011-07-08 V3-d genomic region of interest sequencing strategies
PCT/NL2011/050504 WO2012005595A2 (en) 2010-07-09 2011-07-08 V3-d genomic region of interest sequencing strategies

Publications (1)

Publication Number Publication Date
PL2591125T3 true PL2591125T3 (pl) 2018-09-28

Family

ID=44629077

Family Applications (2)

Application Number Title Priority Date Filing Date
PL11736190T PL2591125T3 (pl) 2010-07-09 2011-07-08 Strategie sekwencjonowania będącego przedmiotem zainteresowania genomowego regionu 3-d
PL18163123T PL3360975T3 (pl) 2010-07-09 2011-07-08 Strategie sekwencjonowania 3d regionu genomowego będącego przedmiotem zainteresowania

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL18163123T PL3360975T3 (pl) 2010-07-09 2011-07-08 Strategie sekwencjonowania 3d regionu genomowego będącego przedmiotem zainteresowania

Country Status (26)

Country Link
US (2) US12006538B2 (enExample)
EP (3) EP2591125B1 (enExample)
JP (1) JP5977234B2 (enExample)
KR (1) KR101862756B1 (enExample)
CN (1) CN103180459B (enExample)
AU (1) AU2011274642B2 (enExample)
BR (1) BR112013000552B8 (enExample)
CA (1) CA2804450C (enExample)
CY (1) CY1121702T1 (enExample)
DK (2) DK3360975T3 (enExample)
ES (2) ES2916339T3 (enExample)
HR (1) HRP20180593T1 (enExample)
HU (1) HUE037359T2 (enExample)
IL (2) IL224127B (enExample)
LT (1) LT2591125T (enExample)
NO (1) NO2591125T3 (enExample)
NZ (1) NZ606228A (enExample)
PL (2) PL2591125T3 (enExample)
PT (2) PT3360975T (enExample)
RS (1) RS57295B1 (enExample)
RU (1) RU2603082C2 (enExample)
SG (1) SG186954A1 (enExample)
SI (1) SI2591125T1 (enExample)
SM (1) SMT201800213T1 (enExample)
WO (1) WO2012005595A2 (enExample)
ZA (1) ZA201300375B (enExample)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010126614A2 (en) 2009-04-30 2010-11-04 Good Start Genetics, Inc. Methods and compositions for evaluating genetic markers
US12129514B2 (en) 2009-04-30 2024-10-29 Molecular Loop Biosolutions, Llc Methods and compositions for evaluating genetic markers
PT3360975T (pt) 2010-07-09 2022-04-11 Cergentis B V Estratégias de sequenciamento da região genómica de interesse 3-d
US9163281B2 (en) 2010-12-23 2015-10-20 Good Start Genetics, Inc. Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction
HK1199745A1 (en) 2011-09-09 2015-07-17 The Board Of Trustees Of The Leland Stanford Junior University Methods for obtaining a sequence
JP2014531908A (ja) 2011-10-14 2014-12-04 プレジデント アンド フェローズ オブ ハーバード カレッジ 構造アッセンブリによる配列決定
US9228233B2 (en) 2011-10-17 2016-01-05 Good Start Genetics, Inc. Analysis methods
EP4249605B1 (en) 2011-12-22 2024-08-28 President And Fellows Of Harvard College Methods for analyte detection
ES2991004T3 (es) 2011-12-22 2024-12-02 Harvard College Métodos para la detección de analitos
US8209130B1 (en) 2012-04-04 2012-06-26 Good Start Genetics, Inc. Sequence assembly
US10227635B2 (en) 2012-04-16 2019-03-12 Molecular Loop Biosolutions, Llc Capture reactions
US9914967B2 (en) 2012-06-05 2018-03-13 President And Fellows Of Harvard College Spatial sequencing of nucleic acids using DNA origami probes
GB2519255B (en) * 2013-02-01 2016-01-06 Univ California Methods for genome assembly and haplotype phasing
US9411930B2 (en) * 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
EP2959011A1 (en) * 2013-02-19 2015-12-30 Cergentis B.V. Sequencing strategies for genomic regions of interest
EP3578666A1 (en) 2013-03-12 2019-12-11 President and Fellows of Harvard College Method of generating a three-dimensional nucleic acid containing matrix
WO2014152421A1 (en) 2013-03-14 2014-09-25 Good Start Genetics, Inc. Methods for analyzing nucleic acids
WO2014144491A1 (en) * 2013-03-15 2014-09-18 The Broad Institute, Inc Methods for determining multiple interactions between nucleic acids in a cell
US10287621B2 (en) 2013-04-11 2019-05-14 Pelin Sahlén Targeted chromosome conformation capture
WO2014197568A2 (en) 2013-06-04 2014-12-11 President And Fellows Of Harvard College Rna-guideded transcriptional regulation
WO2015010051A1 (en) * 2013-07-19 2015-01-22 Ludwig Institute For Cancer Research Whole-genome and targeted haplotype reconstruction
GB2517936B (en) * 2013-09-05 2016-10-19 Babraham Inst Chromosome conformation capture method including selection and enrichment steps
EP3049557B1 (en) 2013-09-27 2021-05-05 University of Washington Methods and systems for large scale scaffolding of genome assemblies
US10851414B2 (en) 2013-10-18 2020-12-01 Good Start Genetics, Inc. Methods for determining carrier status
GB201320351D0 (en) * 2013-11-18 2014-01-01 Erasmus Universiteit Medisch Ct Method
WO2015175530A1 (en) 2014-05-12 2015-11-19 Gore Athurva Methods for detecting aneuploidy
EP2960818A1 (en) * 2014-06-24 2015-12-30 Institut Pasteur Method, device, and computer program for assembling pieces of chromosomes from one or several organisms
WO2016007839A1 (en) 2014-07-11 2016-01-14 President And Fellows Of Harvard College Methods for high-throughput labelling and detection of biological features in situ using microscopy
US10526641B2 (en) 2014-08-01 2020-01-07 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
US20160048608A1 (en) 2014-08-15 2016-02-18 Good Start Genetics, Inc. Systems and methods for genetic analysis
WO2016040446A1 (en) 2014-09-10 2016-03-17 Good Start Genetics, Inc. Methods for selectively suppressing non-target sequences
US10429399B2 (en) 2014-09-24 2019-10-01 Good Start Genetics, Inc. Process control for increased robustness of genetic assays
EP3227462B1 (en) * 2014-12-01 2020-04-22 The Broad Institute, Inc. Method for in situ determination of nucleic acid proximity
EP4095261B1 (en) 2015-01-06 2025-05-28 Molecular Loop Biosciences, Inc. Screening for structural variants
KR102721363B1 (ko) 2015-02-17 2024-10-23 더브테일 제노믹스 엘엘씨 핵산 서열 어셈블리
WO2016154540A1 (en) 2015-03-26 2016-09-29 Dovetail Genomics Llc Physical linkage preservation in dna storage
US10395759B2 (en) * 2015-05-18 2019-08-27 Regeneron Pharmaceuticals, Inc. Methods and systems for copy number variant detection
US12018314B2 (en) 2015-07-02 2024-06-25 Arima Genomics, Inc. Accurate molecular deconvolution of mixture samples
US20180282799A1 (en) * 2015-10-05 2018-10-04 Koninklijke Nederlandse Akademie Van Wetenschappen Targeted locus amplification using cloning strategies
EP3366818B1 (en) * 2015-10-19 2021-04-14 Zhejiang Annoroad Bio-Technology Co., Ltd. Method for constructing high-resolution single cell hi-c library with a lot of information
AU2016341198B2 (en) 2015-10-19 2023-03-09 Dovetail Genomics, Llc Methods for genome assembly, haplotype phasing, and target independent nucleic acid detection
GB201518843D0 (en) * 2015-10-23 2015-12-09 Isis Innovation Method of analysing DNA sequences
HK1252878A1 (zh) 2015-11-03 2019-06-06 President And Fellows Of Harvard College 用於含有基质的三维核酸的体积成像的方法和设备
EP4144861B1 (en) 2015-12-04 2024-09-11 10X Genomics, Inc. Methods and compositions for nucleic acid analysis
US10975417B2 (en) 2016-02-23 2021-04-13 Dovetail Genomics, Llc Generation of phased read-sets for genome assembly and haplotype phasing
JP7259182B2 (ja) 2016-04-25 2023-04-18 プレジデント アンド フェローズ オブ ハーバード カレッジ in situ分子検出のためのハイブリダイゼーション連鎖反応法
GB201608000D0 (en) * 2016-05-06 2016-06-22 Oxford Biodynamics Ltd Chromosome detection
CN105839196B (zh) * 2016-05-11 2018-04-17 北京百迈客生物科技有限公司 一种真核生物DNA的Hi‑C高通量测序建库方法
CN109477101B (zh) 2016-05-13 2022-11-18 多弗泰尔基因组学有限责任公司 从保存的样品中回收长范围连锁信息
KR101915701B1 (ko) * 2016-06-16 2018-11-07 한국한의학연구원 돌연변이 발생률의 측정 방법
EP3507364A4 (en) 2016-08-31 2020-05-20 President and Fellows of Harvard College METHODS OF GENERATING NUCLEIC ACID SEQUENCE LIBRARIES FOR IN SITU FLUORESCENT SEQUENCING DETECTION
WO2018045186A1 (en) 2016-08-31 2018-03-08 President And Fellows Of Harvard College Methods of combining the detection of biomolecules into a single assay using fluorescent in situ sequencing
ES2971286T3 (es) * 2016-12-01 2024-06-04 Oxford BioDynamics PLC Aplicación de interacciones cromosómicas epigenéticas en diagnóstico de cáncer
EP3448396A4 (en) 2017-04-14 2020-01-22 President and Fellows of Harvard College METHODS OF GENERATING A CELL-DERIVED MICROFILAMENT ARRAY
CN107119120A (zh) * 2017-05-04 2017-09-01 河海大学常州校区 一种基于染色质3d构象技术的关键作用分子检测方法
WO2019104034A1 (en) * 2017-11-21 2019-05-31 Arima Genomics, Inc. Preserving spatial-proximal contiguity and molecular contiguity in nucleic acid templates
WO2019152543A1 (en) 2018-01-31 2019-08-08 Dovetail Genomics, Llc Sample prep for dna linkage recovery
WO2019199579A1 (en) 2018-04-09 2019-10-17 The Board Of Trustees Of The Leland Stanford Junior University Method of in situ gene sequencing
SG11202101934SA (en) 2018-07-30 2021-03-30 Readcoor Llc Methods and systems for sample processing or analysis
WO2020076976A1 (en) 2018-10-10 2020-04-16 Readcoor, Inc. Three-dimensional spatial molecular indexing
US20220251640A1 (en) * 2019-05-17 2022-08-11 The Broad Institute, Inc. Methods of determination of genome architecture and epigenetic profile
WO2021224225A1 (en) 2020-05-04 2021-11-11 Cergentis B.V. Method
GB202006550D0 (en) 2020-05-04 2020-06-17 Cergentis B V Method
GB202006546D0 (en) 2020-05-04 2020-06-17 Cergentis B V Method
WO2021224233A1 (en) 2020-05-04 2021-11-11 Cergentis B.V. Method
US20220049303A1 (en) 2020-08-17 2022-02-17 Readcoor, Llc Methods and systems for spatial mapping of genetic variants
WO2022114957A1 (en) 2020-11-26 2022-06-02 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Personalized tumor markers
EP4352254A4 (en) * 2021-05-21 2025-04-16 The Board Of Trustees Of The Leland Stanford Junior University NEXT-GENERATION VOLUMETRIC IN-SITU SEQUENCED ANALYSIS
GB202111194D0 (en) 2021-08-03 2021-09-15 Cergentis B V Method

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077204A (en) * 1984-06-21 1991-12-31 Chiron Corporation Yeast endopeptidase for basic amino-acid site cleavage, preparation and use
US9328391B1 (en) 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
JPS6226300A (ja) 1984-10-10 1987-02-04 セントコ−・インコ−ポレ−テツド Htlv−3dnaのクロ−ニングおよび発現
US5221518A (en) * 1984-12-14 1993-06-22 Mills Randell L DNA sequencing apparatus
US5258507A (en) * 1990-11-08 1993-11-02 Amoco Corporation Labeling reagents useful for the chemical attachment of nitrophenyl derivative ligands to DNA probes
US6060644A (en) * 1994-03-24 2000-05-09 Iowa State University Research Foundation, Inc. Isolation and use of cuticular lipid genes
CA2255774C (en) * 1996-05-29 2008-03-18 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
JP2002500623A (ja) * 1996-11-07 2002-01-08 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニヴァーシティー スプルーティタンパク質およびコーディング配列
US6261804B1 (en) * 1997-01-21 2001-07-17 The General Hospital Corporation Selection of proteins using RNA-protein fusions
CA2281205A1 (en) * 1997-02-12 1998-08-13 Eugene Y. Chan Methods and products for analyzing polymers
BR9815578A (pt) * 1997-12-02 2001-10-23 Du Pont Fragmento de ácido nucléico, gene quimérico, célula hospedeira, polipeptìdeos, método de alteração do nìvel de expressão de uma enzima biossintética, método de obtenção de um fragmento de ácido nucléico, e método de avalição da capacidade de pelo menos um composto em inibir a atividade de uma enzima biossintética
US6455692B1 (en) * 1998-08-04 2002-09-24 Transgenomic, Inc. Method of concentrating polynucleotides using MIPC
US6291168B1 (en) * 1998-10-27 2001-09-18 Auburn University Nucleic acid sequences diagnostic for pathogenic E.coli O157:H7, methods of identification and kit therefore
US20050232900A1 (en) * 1999-05-18 2005-10-20 Crucell Holland B.V. Serotype of adenovirus and uses thereof
AU1824101A (en) * 1999-06-18 2001-01-09 Elitra Pharmaceuticals, Inc. Nucleotide sequences of moraxella catarrhalis genome
US7470507B2 (en) * 1999-09-01 2008-12-30 Whitehead Institute For Biomedical Research Genome-wide location and function of DNA binding proteins
US20040014195A1 (en) * 1999-12-29 2004-01-22 Diversa Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
US20060292560A1 (en) * 2000-08-14 2006-12-28 Robert Burgess Transcription factor target gene discovery
US6709861B2 (en) * 2000-11-17 2004-03-23 Lucigen Corp. Cloning vectors and vector components
US20030054347A1 (en) * 2001-04-27 2003-03-20 The Regents Of The University Of Michigan Latrophilin Polynucleotides
US20030013863A1 (en) * 2001-07-16 2003-01-16 Buchholz Wallace G. High resolution DNA size standards
US20030157705A1 (en) * 2001-08-10 2003-08-21 Fodor William L. Engineered recombinant molecule that regulates humoral and cellular effector functions of the immune system
AUPR823601A0 (en) * 2001-10-12 2001-11-08 University Of Queensland, The Automated genotyping
AU2003237312A1 (en) * 2002-05-29 2003-12-19 University Of Washington Mutants of gad65 and ian5 relating to diabetes
CA2497338A1 (en) * 2002-08-30 2004-03-18 Japan Science And Technology Corporation Method of targeted gene disruption, genome of hyperthermostable bacterium and genome chip using the same
US7919235B2 (en) * 2002-09-30 2011-04-05 F. Hoffman-La Roche Ag Oligonucleotides for genotyping thymidylate synthase gene
US7575865B2 (en) * 2003-01-29 2009-08-18 454 Life Sciences Corporation Methods of amplifying and sequencing nucleic acids
EP1601688A2 (en) * 2003-03-06 2005-12-07 Children's Hospital, Inc. Genes of an otitis media isolate of nontypeable haemophilus influenzae
FR2852317B1 (fr) * 2003-03-13 2006-08-04 Biopuces a sondes et leurs methodes d'utilisation
WO2005026203A2 (en) * 2003-09-18 2005-03-24 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Dna promoters and anthrax vaccines
US20060150283A1 (en) * 2004-02-13 2006-07-06 Nickolai Alexandrov Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
US20060107345A1 (en) * 2003-09-30 2006-05-18 Nickolai Alexandrov Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
US20050221341A1 (en) * 2003-10-22 2005-10-06 Shimkets Richard A Sequence-based karyotyping
JP2007512811A (ja) * 2003-11-10 2007-05-24 インベスチゲン, インコーポレイテッド 検出のための核酸を調製する方法
AU2005284980A1 (en) * 2004-09-10 2006-03-23 Sequenom, Inc. Methods for long-range sequence analysis of nucleic acids
US20070048748A1 (en) * 2004-09-24 2007-03-01 Li-Cor, Inc. Mutant polymerases for sequencing and genotyping
US20060223073A1 (en) * 2005-03-31 2006-10-05 Boyes Barry E Methods of using a DNase I-like enzyme
EP1910537A1 (en) * 2005-06-06 2008-04-16 454 Life Sciences Corporation Paired end sequencing
US8407013B2 (en) * 2005-06-07 2013-03-26 Peter K. Rogan AB initio generation of single copy genomic probes
EP2620510B2 (en) * 2005-06-15 2020-02-19 Complete Genomics Inc. Single molecule arrays for genetic and chemical analysis
EP1910562B1 (en) * 2005-06-23 2010-12-08 Keygene N.V. Strategies for high throughput identification and detection of polymorphisms
EP1910563B1 (en) * 2005-06-23 2010-04-21 Keygene N.V. Improved strategies for sequencing complex genomes using high throughput sequencing technologies
PL1899488T3 (pl) 2005-07-04 2016-03-31 Erasmus Univ Medical Center Test uchwytu konformacji chromosomu na czipie (4C)
WO2007025190A2 (en) * 2005-08-25 2007-03-01 Whitehead Institute For Biomedical Research Novel methods for genome-wide location analysis
US20090221428A1 (en) * 2005-09-07 2009-09-03 Young Richard A Methods of Genome-Wide Location Analysis in Stem Cells
US8071310B2 (en) 2005-11-14 2011-12-06 Keygene Nv Method for the high throughput screening of transposon tagging populations and massive parallel sequence identification of insertion sites
JP5285431B2 (ja) * 2005-12-28 2013-09-11 ザ ユーエイビー リサーチ ファウンデイション 肺炎球菌血清型
GB0603251D0 (en) * 2006-02-17 2006-03-29 Isis Innovation DNA conformation
EP2043728A2 (en) 2006-07-11 2009-04-08 Microchips, Inc. Multi-reservoir pump device for dialysis, biosensing, or delivery of substances
EP2049682A2 (en) * 2006-07-31 2009-04-22 Illumina Cambridge Limited Method of library preparation avoiding the formation of adaptor dimers
WO2008064837A2 (en) * 2006-11-27 2008-06-05 Dsm Ip Assets B.V. Novel genes for the fermentative production of hydroxytyrosol
EP3285067B1 (en) * 2006-12-14 2022-06-22 Life Technologies Corporation Apparatus for measuring analytes using fet arrays
EP2121977B1 (en) * 2007-01-11 2017-06-21 Erasmus University Medical Center Circular chromosome conformation capture (4c)
US7835871B2 (en) * 2007-01-26 2010-11-16 Illumina, Inc. Nucleic acid sequencing system and method
JPWO2008111453A1 (ja) * 2007-03-07 2010-06-24 国立大学法人 東京大学 Dna断片の増幅方法
US20080248958A1 (en) * 2007-04-05 2008-10-09 Hollenbach Andrew D System for pulling out regulatory elements in vitro
US7932030B2 (en) * 2007-04-05 2011-04-26 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College System for pulling out regulatory elements using yeast
CN101720359A (zh) * 2007-06-01 2010-06-02 454生命科学公司 从多重混合物中识别个别样本的系统和方法
EP2053132A1 (en) 2007-10-23 2009-04-29 Roche Diagnostics GmbH Enrichment and sequence analysis of geomic regions
US8518640B2 (en) * 2007-10-29 2013-08-27 Complete Genomics, Inc. Nucleic acid sequencing and process
US8263367B2 (en) * 2008-01-25 2012-09-11 Agency For Science, Technology And Research Nucleic acid interaction analysis
US8296075B2 (en) * 2008-05-21 2012-10-23 Mito Tech, LLC Computer system and computer-facilitated method for nucleic acid sequence alignment and analysis
CN102203251A (zh) * 2008-05-23 2011-09-28 生命科技公司 用于dna提取的方法和试剂盒
FR2945545B1 (fr) * 2009-05-14 2011-08-05 Univ Aix Marseille Ii Methode de detection d'adn procaryote extrait d'un echantillon de selles
JP2013503605A (ja) * 2009-09-01 2013-02-04 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ マイクロアレイの選択のためのデバイス及び方法
EP2354243A1 (en) 2010-02-03 2011-08-10 Lexogen GmbH Complexity reduction method
JP5901046B2 (ja) * 2010-02-19 2016-04-06 国立大学法人 千葉大学 OATP1B3mRNAの新規な選択的スプライシングバリアント
PT3360975T (pt) 2010-07-09 2022-04-11 Cergentis B V Estratégias de sequenciamento da região genómica de interesse 3-d
US10858699B2 (en) * 2016-08-30 2020-12-08 Integrated Dna Technologies, Inc. Cleavable hairpin primers

Also Published As

Publication number Publication date
ZA201300375B (en) 2014-03-26
CA2804450C (en) 2022-10-11
WO2012005595A2 (en) 2012-01-12
ES2667346T9 (es) 2018-06-11
PT2591125T (pt) 2018-05-09
EP4063518A1 (en) 2022-09-28
AU2011274642B2 (en) 2015-05-21
IL256509B (en) 2020-02-27
WO2012005595A3 (en) 2012-03-08
BR112013000552B8 (pt) 2023-01-17
DK2591125T3 (en) 2018-05-14
SMT201800213T1 (it) 2018-07-17
EP2591125A2 (en) 2013-05-15
HUE037359T2 (hu) 2018-08-28
EP2591125B1 (en) 2018-04-04
SG186954A1 (en) 2013-02-28
EP3360975A1 (en) 2018-08-15
CN103180459A (zh) 2013-06-26
KR20130049808A (ko) 2013-05-14
JP2013530709A (ja) 2013-08-01
WO2012005595A8 (en) 2012-04-26
RU2013105459A (ru) 2014-08-20
BR112013000552A2 (pt) 2016-05-24
US12006538B2 (en) 2024-06-11
IL224127B (en) 2018-01-31
NZ606228A (en) 2014-12-24
RS57295B1 (sr) 2018-08-31
ES2667346T3 (es) 2018-05-10
HRP20180593T1 (hr) 2018-07-27
DK3360975T3 (da) 2022-04-11
PT3360975T (pt) 2022-04-11
RU2603082C2 (ru) 2016-11-20
US20130183672A1 (en) 2013-07-18
SI2591125T1 (en) 2018-08-31
LT2591125T (lt) 2018-07-25
CN103180459B (zh) 2016-10-19
EP3360975B1 (en) 2022-03-30
JP5977234B2 (ja) 2016-08-24
NO2591125T3 (enExample) 2018-09-01
AU2011274642A1 (en) 2013-02-21
BR112013000552B1 (pt) 2021-03-02
IL256509A (en) 2018-02-28
PL3360975T3 (pl) 2022-07-11
CA2804450A1 (en) 2012-01-12
US20250066846A1 (en) 2025-02-27
ES2916339T3 (es) 2022-06-30
KR101862756B1 (ko) 2018-05-30
CY1121702T1 (el) 2020-07-31

Similar Documents

Publication Publication Date Title
IL256509B (en) Strategies for sequencing a genomic region of interest
GB2499340B (en) Methods for sequencing nucleic acids
PT3623481T (pt) Composições para sequenciação de ácidos nucleicos
GB2498163B (en) High-throughput immune sequencing
ZA201304280B (en) Treatment of jak2-mediated conditions
GB201003274D0 (en) Methods of connecting
IL223257A0 (en) Method of dna sequencing by hybridisation
EP2539468A4 (en) DIAGNOSTIC PROCEDURE INCLUDING LOSS OF HETEROZYGOTY
IL223256A0 (en) Method of dna sequencing by polymerisation
PL2621619T3 (pl) Sposób mieszania
ZA201209620B (en) Polymorphs of osi-906
EP2649993A4 (en) STABILIZER OF ACETAMINOPHENE
IL226536A (en) DNA position-oriented change
GB2502195B (en) Purification of nucleic acids
PL390780A1 (pl) Sposób biologiczny zwalczania warrozy
GB201016452D0 (en) Rapid extrection of nucleic acids
TWM389753U (en) Improved structure of handle
HU1000688D0 (en) Use of trifluoro-phal
GB201004059D0 (en) Method of construction
PL119515U1 (pl) Zestaw elementów do pokrycia dachu
GB201011066D0 (en) Optical mapping of genomic DNA
GB201021491D0 (en) Optical mapping of genomic dna
GB201021026D0 (en) Optical mapping of genomic DNA
GB201016194D0 (en) Optical mapping of genomic dna
GB201009332D0 (en) Optical mapping of genomic DNA