PL2585104T3 - Sposoby i kompozycje do dostarczania arylosulfatazy a do oun - Google Patents
Sposoby i kompozycje do dostarczania arylosulfatazy a do ounInfo
- Publication number
- PL2585104T3 PL2585104T3 PL11799037T PL11799037T PL2585104T3 PL 2585104 T3 PL2585104 T3 PL 2585104T3 PL 11799037 T PL11799037 T PL 11799037T PL 11799037 T PL11799037 T PL 11799037T PL 2585104 T3 PL2585104 T3 PL 2585104T3
- Authority
- PL
- Poland
- Prior art keywords
- arylsulfatase
- compositions
- methods
- cns delivery
- cns
- Prior art date
Links
- 102100022146 Arylsulfatase A Human genes 0.000 title 1
- 108010036867 Cerebroside-Sulfatase Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/54—Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/06—Sulfuric ester hydrolases (3.1.6)
- C12Y301/06013—Iduronate-2-sulfatase (3.1.6.13)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35885710P | 2010-06-25 | 2010-06-25 | |
US36078610P | 2010-07-01 | 2010-07-01 | |
US38786210P | 2010-09-29 | 2010-09-29 | |
US201161435710P | 2011-01-24 | 2011-01-24 | |
US201161442115P | 2011-02-11 | 2011-02-11 | |
US201161476210P | 2011-04-15 | 2011-04-15 | |
US201161495268P | 2011-06-09 | 2011-06-09 | |
EP11799037.4A EP2585104B1 (en) | 2010-06-25 | 2011-06-25 | Methods and compositions for cns delivery of arylsulfatase a |
PCT/US2011/041926 WO2011163650A2 (en) | 2010-06-25 | 2011-06-25 | Methods and compositions for cns delivery of arylsulfatase a |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2585104T3 true PL2585104T3 (pl) | 2020-01-31 |
Family
ID=46888844
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL19192508T PL3626257T3 (pl) | 2010-06-25 | 2011-06-25 | Sposoby i kompozycje do dostarczania arylosulfatazy a do oun |
PL11799037T PL2585104T3 (pl) | 2010-06-25 | 2011-06-25 | Sposoby i kompozycje do dostarczania arylosulfatazy a do oun |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL19192508T PL3626257T3 (pl) | 2010-06-25 | 2011-06-25 | Sposoby i kompozycje do dostarczania arylosulfatazy a do oun |
Country Status (25)
Country | Link |
---|---|
US (1) | US9770410B2 (pl) |
EP (3) | EP3964230A1 (pl) |
JP (1) | JP6045493B2 (pl) |
KR (5) | KR20230079472A (pl) |
CN (1) | CN103282046B (pl) |
AU (4) | AU2011270670B2 (pl) |
BR (1) | BR112012033216B1 (pl) |
CA (1) | CA2803003C (pl) |
CY (2) | CY1122282T1 (pl) |
DK (1) | DK2585104T3 (pl) |
ES (1) | ES2754776T3 (pl) |
HR (1) | HRP20191923T1 (pl) |
IL (3) | IL291556B2 (pl) |
LT (1) | LT2585104T (pl) |
ME (1) | ME03647B (pl) |
MX (1) | MX344795B (pl) |
NZ (2) | NZ605873A (pl) |
PL (2) | PL3626257T3 (pl) |
RS (1) | RS59468B1 (pl) |
RU (1) | RU2671503C2 (pl) |
SI (1) | SI2585104T1 (pl) |
TW (1) | TWI667037B (pl) |
UA (1) | UA115650C2 (pl) |
WO (1) | WO2011163650A2 (pl) |
ZA (1) | ZA201300675B (pl) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
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NZ605865A (en) | 2010-06-25 | 2015-07-31 | Shire Human Genetic Therapies | Cns delivery of therapeutic agents |
DK2585104T3 (da) | 2010-06-25 | 2019-10-14 | Shire Human Genetic Therapies | Fremgangsmåder og sammensætninger tilcns-levering af arylsulfatase a |
WO2011163647A2 (en) | 2010-06-25 | 2011-12-29 | Shire Human Genetic Therapies, Inc. | Methods and compositions for cns delivery of heparan n-sulfatase |
EP2593131B1 (en) | 2010-06-25 | 2019-08-21 | Shire Human Genetic Therapies, Inc. | Methods and compositions for cns delivery of iduronate-2-sulfatase |
NZ702800A (en) | 2010-06-25 | 2017-03-31 | Shire Human Genetic Therapies | Methods and compositions for cns delivery of heparan n-sulfatase |
WO2013096899A2 (en) | 2011-12-23 | 2013-06-27 | Shire Human Genetic Therapies, Inc. | Stable formulations for cns delivery of arylsulfatase a |
WO2014110246A1 (en) | 2013-01-09 | 2014-07-17 | Shire Human Genetic Therapies, Inc. | Methods for purification of arylsulfatase a |
KR20160010526A (ko) * | 2013-05-15 | 2016-01-27 | 리젠츠 오브 더 유니버시티 오브 미네소타 | 중추 신경계로의 아데노-연관 바이러스 매개 유전자 전달 |
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CA2986508C (en) * | 2015-07-10 | 2021-06-15 | Synthon Biopharmaceuticals B.V. | Compositions comprising antibody-duocarmycin drug conjugates |
US11020461B2 (en) * | 2016-02-17 | 2021-06-01 | Takeda Pharmaceutical Company Limited | Methods and compositions for CNS delivery of arylsulfatase A |
KR20230162139A (ko) * | 2016-06-01 | 2023-11-28 | 세르비에 아이피 유케이 리미티드 | 폴리알킬렌 옥시드-아스파라기나제의 제형, 및 그의 제조 및 사용 방법 |
MX2019007824A (es) * | 2016-12-28 | 2019-09-09 | Japan Chem Res | Preparacion liofilizada. |
BR112020005249A2 (pt) | 2017-09-22 | 2020-09-24 | The Trustees Of The University Of Pennsylvania | terapia de gene para tratar mucopolissacaridose tipo ii |
RU2020123718A (ru) | 2017-12-19 | 2022-01-20 | Шайр Хьюман Дженетик Терапиз, Инк. | Очищенная арилсульфатаза a и композиции на ее основе |
EP3811962A4 (en) * | 2018-06-25 | 2022-03-16 | JCR Pharmaceuticals Co., Ltd. | PROTEIN AQUEOUS LIQUID FORMULATION |
WO2021061517A1 (en) * | 2019-09-23 | 2021-04-01 | University Of Washington | Assay of arylsulfatase a enzymatic activity in dried blood spots by mass spectrometry and fluorometry |
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US4743265A (en) | 1986-04-23 | 1988-05-10 | Dij Catheter Corp | Articulated catheter placement device |
US5863782A (en) | 1995-04-19 | 1999-01-26 | Women's And Children's Hospital | Synthetic mammalian sulphamidase and genetic sequences encoding same |
US6118045A (en) | 1995-08-02 | 2000-09-12 | Pharming B.V. | Lysosomal proteins produced in the milk of transgenic animals |
ES2185117T3 (es) | 1997-08-22 | 2003-04-16 | Seikagaku Kogyo Co Ltd | Agente terapeutico para disco intervertebral herniado. |
PT1137762E (pt) | 1998-12-07 | 2009-01-14 | Genzyme Corp | Tratamento da doença de pompe |
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DK2585104T3 (da) | 2010-06-25 | 2019-10-14 | Shire Human Genetic Therapies | Fremgangsmåder og sammensætninger tilcns-levering af arylsulfatase a |
WO2011163651A2 (en) | 2010-06-25 | 2011-12-29 | Shire Human Genetic Therapies, Inc. | METHODS AND COMPOSITIONS FOR CNS DELIVERY OF β-GALACTOCEREBROSIDASE |
NZ702800A (en) | 2010-06-25 | 2017-03-31 | Shire Human Genetic Therapies | Methods and compositions for cns delivery of heparan n-sulfatase |
NZ605865A (en) | 2010-06-25 | 2015-07-31 | Shire Human Genetic Therapies | Cns delivery of therapeutic agents |
WO2011163647A2 (en) | 2010-06-25 | 2011-12-29 | Shire Human Genetic Therapies, Inc. | Methods and compositions for cns delivery of heparan n-sulfatase |
EP2593131B1 (en) | 2010-06-25 | 2019-08-21 | Shire Human Genetic Therapies, Inc. | Methods and compositions for cns delivery of iduronate-2-sulfatase |
CA2805449A1 (en) | 2010-06-25 | 2011-12-29 | Shire Human Genetic Therapies, Inc. | Treatment of sanfilippo syndrome type b |
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2011
- 2011-06-25 DK DK11799037.4T patent/DK2585104T3/da active
- 2011-06-25 KR KR1020237017347A patent/KR20230079472A/ko not_active Application Discontinuation
- 2011-06-25 KR KR1020207008105A patent/KR102318997B1/ko active IP Right Grant
- 2011-06-25 JP JP2013516846A patent/JP6045493B2/ja active Active
- 2011-06-25 CN CN201180040802.XA patent/CN103282046B/zh active Active
- 2011-06-25 NZ NZ605873A patent/NZ605873A/en unknown
- 2011-06-25 KR KR1020187014958A patent/KR102094094B1/ko active IP Right Grant
- 2011-06-25 MX MX2013000323A patent/MX344795B/es active IP Right Grant
- 2011-06-25 SI SI201131776T patent/SI2585104T1/sl unknown
- 2011-06-25 US US13/168,963 patent/US9770410B2/en active Active
- 2011-06-25 EP EP21189310.2A patent/EP3964230A1/en active Pending
- 2011-06-25 UA UAA201214685A patent/UA115650C2/uk unknown
- 2011-06-25 WO PCT/US2011/041926 patent/WO2011163650A2/en active Application Filing
- 2011-06-25 RS RSP20191354 patent/RS59468B1/sr unknown
- 2011-06-25 EP EP19192508.0A patent/EP3626257B1/en active Active
- 2011-06-25 CA CA2803003A patent/CA2803003C/en active Active
- 2011-06-25 IL IL291556A patent/IL291556B2/en unknown
- 2011-06-25 NZ NZ702799A patent/NZ702799A/en unknown
- 2011-06-25 RU RU2012154574A patent/RU2671503C2/ru active
- 2011-06-25 ES ES11799037T patent/ES2754776T3/es active Active
- 2011-06-25 EP EP11799037.4A patent/EP2585104B1/en active Active
- 2011-06-25 AU AU2011270670A patent/AU2011270670B2/en active Active
- 2011-06-25 ME MEP-2019-298A patent/ME03647B/me unknown
- 2011-06-25 PL PL19192508T patent/PL3626257T3/pl unknown
- 2011-06-25 LT LT11799037T patent/LT2585104T/lt unknown
- 2011-06-25 KR KR1020217034302A patent/KR102537084B1/ko active IP Right Grant
- 2011-06-25 BR BR112012033216-3A patent/BR112012033216B1/pt active IP Right Grant
- 2011-06-25 KR KR1020137001752A patent/KR101997935B1/ko active IP Right Grant
- 2011-06-25 PL PL11799037T patent/PL2585104T3/pl unknown
- 2011-06-27 TW TW100122533A patent/TWI667037B/zh active
-
2012
- 2012-12-20 IL IL223758A patent/IL223758B/en active IP Right Grant
-
2013
- 2013-01-25 ZA ZA2013/00675A patent/ZA201300675B/en unknown
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2017
- 2017-04-06 AU AU2017202289A patent/AU2017202289B2/en active Active
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2019
- 2019-06-11 AU AU2019204051A patent/AU2019204051B2/en active Active
- 2019-10-22 HR HRP20191923TT patent/HRP20191923T1/hr unknown
- 2019-11-13 CY CY20191101190T patent/CY1122282T1/el unknown
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2020
- 2020-04-06 IL IL273854A patent/IL273854B/en unknown
-
2021
- 2021-09-24 AU AU2021236557A patent/AU2021236557A1/en active Pending
- 2021-11-02 CY CY20211100942T patent/CY1124910T1/el unknown
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