PL2563904T3 - Udoskonalona pożywka do hodowli komórkowej - Google Patents
Udoskonalona pożywka do hodowli komórkowejInfo
- Publication number
- PL2563904T3 PL2563904T3 PL11717240T PL11717240T PL2563904T3 PL 2563904 T3 PL2563904 T3 PL 2563904T3 PL 11717240 T PL11717240 T PL 11717240T PL 11717240 T PL11717240 T PL 11717240T PL 2563904 T3 PL2563904 T3 PL 2563904T3
- Authority
- PL
- Poland
- Prior art keywords
- culture medium
- cell culture
- improved cell
- improved
- medium
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0031—Serum-free culture media
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32783610P | 2010-04-26 | 2010-04-26 | |
| PCT/EP2011/056508 WO2011134920A1 (en) | 2010-04-26 | 2011-04-25 | Improved cell culture medium |
| EP11717240.3A EP2563904B1 (en) | 2010-04-26 | 2011-04-25 | Improved cell culture medium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2563904T3 true PL2563904T3 (pl) | 2015-06-30 |
Family
ID=44074260
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11717240T PL2563904T3 (pl) | 2010-04-26 | 2011-04-25 | Udoskonalona pożywka do hodowli komórkowej |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US9428727B2 (e) |
| EP (1) | EP2563904B1 (e) |
| JP (3) | JP6347949B2 (e) |
| KR (1) | KR101828623B1 (e) |
| CN (1) | CN102858952B (e) |
| AU (1) | AU2011246503B2 (e) |
| BR (1) | BR112012027282B1 (e) |
| CA (1) | CA2797356C (e) |
| DK (1) | DK2563904T3 (e) |
| ES (1) | ES2533074T3 (e) |
| IL (1) | IL222452B (e) |
| MX (1) | MX2012012526A (e) |
| PL (1) | PL2563904T3 (e) |
| PT (1) | PT2563904E (e) |
| RU (1) | RU2644651C2 (e) |
| SG (1) | SG185038A1 (e) |
| WO (1) | WO2011134920A1 (e) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
| NZ575328A (en) | 2006-09-13 | 2012-06-29 | Abbott Lab | Cell culture improvements |
| JP5808249B2 (ja) | 2008-10-20 | 2015-11-10 | アッヴィ・インコーポレイテッド | プロテインａアフィニティークロマトグラフィーを用いる抗体の単離および精製 |
| AU2009307737B2 (en) | 2008-10-20 | 2015-07-23 | Abbvie Inc. | Viral inactivation during purification of antibodies |
| MX2012012525A (es) | 2010-04-26 | 2012-11-23 | Novartis Ag | Medio de cultivo mejorado. |
| DK2563904T3 (en) * | 2010-04-26 | 2015-04-07 | Novartis Ag | Improved cell culture medium |
| BR112013009934A2 (pt) * | 2010-12-07 | 2016-07-05 | Hoffmann La Roche | dispositivo para adicionar pelo menos duas soluções de alimentação, aparelho de cultivo celular, uso de um dispositivo e método para obter um polipeptídeo |
| EP2702077A2 (en) | 2011-04-27 | 2014-03-05 | AbbVie Inc. | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
| US10493151B2 (en) | 2011-10-18 | 2019-12-03 | Coherus Biosciences, Inc. | Etanercept formulations stabilized with sodium chloride |
| AU2012326171B2 (en) | 2011-10-18 | 2017-03-09 | Coherus Biosciences, Inc. | Etanercept formulations stabilized with sodium chloride |
| US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
| US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
| WO2013158279A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Protein purification methods to reduce acidic species |
| US20130281355A1 (en) | 2012-04-24 | 2013-10-24 | Genentech, Inc. | Cell culture compositions and methods for polypeptide production |
| US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
| EP2869816A4 (en) | 2012-07-09 | 2016-04-20 | Coherus Biosciences Inc | FORMANTS OF ETANERCEPT HAVING A REDUCTION MARKED IN INVISIBLE PARTICLES IN THE NU |
| CA2883272A1 (en) | 2012-09-02 | 2014-03-06 | Abbvie Inc. | Methods to control protein heterogeneity |
| US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
| DK2895188T3 (en) | 2012-09-11 | 2018-02-26 | Coherus Biosciences Inc | CORRECTLY FOLDED ETHNECCEPT IN HIGH PURITY AND EXCELLENT YIELD |
| CA2905010A1 (en) | 2013-03-12 | 2014-09-18 | Abbvie Inc. | Human antibodies that bind human tnf-alpha and methods of preparing the same |
| US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
| US8921526B2 (en) | 2013-03-14 | 2014-12-30 | Abbvie, Inc. | Mutated anti-TNFα antibodies and methods of their use |
| EP2836515A1 (en) | 2013-03-14 | 2015-02-18 | AbbVie Inc. | Low acidic species compositions and methods for producing and using the same |
| US10196601B2 (en) | 2013-08-20 | 2019-02-05 | Lek Pharmaceuticals D.D. | Cell culture medium and process for controlling α-amidation and/or C-terminal amino acid cleavage of polypeptides |
| WO2015051293A2 (en) | 2013-10-04 | 2015-04-09 | Abbvie, Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
| MX2016004564A (es) * | 2013-10-11 | 2016-07-12 | Regeneron Pharma | Cultivo celular metabolicamente optimizado. |
| US11390663B2 (en) | 2013-10-11 | 2022-07-19 | Regeneron Pharmaceuticals, Inc. | Metabolically optimized cell culture |
| US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
| US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
| US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
| US20150139988A1 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
| WO2015116820A1 (en) | 2014-01-30 | 2015-08-06 | Coherus Biosciences, Inc. | Perfusion media |
| DK3536776T3 (da) | 2014-04-29 | 2024-01-15 | Novartis Ag | Hidtil ukendte vertebratceller og fremgangsmåder til rekombinant ekspression af et polypeptid af interesse |
| EP2975050B1 (en) | 2014-07-18 | 2019-05-29 | Sandoz Ag | Quantification of misfolded TNFR2:Fc |
| US10822584B2 (en) * | 2015-12-17 | 2020-11-03 | Life Technologies Corporation | Pellets used in cell culture and methods of making thereof |
| EP3440190A1 (en) * | 2016-04-05 | 2019-02-13 | Pfizer Inc | Cell culture process |
| CN110520538B (zh) * | 2017-03-31 | 2024-02-20 | 勃林格殷格翰国际公司 | 灌注培养基 |
| WO2018178063A1 (en) * | 2017-03-31 | 2018-10-04 | Boehringer Ingelheim International Gmbh | Perfusion medium |
| JPWO2021090888A1 (e) * | 2019-11-05 | 2021-05-14 | ||
| WO2022036275A2 (en) * | 2020-08-14 | 2022-02-17 | Bristol-Myers Squibb Company | Manufacturing process for protein |
| UY39484A (es) | 2020-11-02 | 2022-06-30 | Novartis Ag | Inhibidores de interleucina-17 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5672502A (en) | 1985-06-28 | 1997-09-30 | Celltech Therapeutics Limited | Animal cell culture |
| EP0283942B1 (en) | 1987-03-24 | 1992-05-20 | W.R. Grace & Co.-Conn. | Basal nutrient medium for cell culture |
| US6048728A (en) * | 1988-09-23 | 2000-04-11 | Chiron Corporation | Cell culture medium for enhanced cell growth, culture longevity, and product expression |
| US5135866A (en) | 1989-03-03 | 1992-08-04 | W. R. Grace & Co.-Conn. | Very low protein nutrient medium for cell culture |
| CA2001550A1 (en) | 1989-03-03 | 1990-09-03 | Aaron H. Heifetz | Very low protein nutrient medium for cell culture |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| GB9022545D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Culture medium |
| JPH0789908B2 (ja) | 1991-02-28 | 1995-10-04 | 倉敷紡績株式会社 | 動物細胞培養用無血清培地 |
| GB9118664D0 (en) * | 1991-08-30 | 1991-10-16 | Celltech Ltd | Cell culture |
| US5856179A (en) | 1994-03-10 | 1999-01-05 | Genentech, Inc. | Polypeptide production in animal cell culture |
| US5830761A (en) | 1995-06-07 | 1998-11-03 | Genetics Institute, Inc. | Medium and methods for culturing mammalian cho cells |
| JP2000517188A (ja) * | 1996-08-30 | 2000-12-26 | ライフ テクノロジーズ，インコーポレイテッド | 無血清哺乳動物細胞培養培地およびその使用 |
| US5804420A (en) | 1997-04-18 | 1998-09-08 | Bayer Corporation | Preparation of recombinant Factor VIII in a protein free medium |
| US6406909B1 (en) | 1998-07-10 | 2002-06-18 | Chugai Seiyaku Kabushiki Kaisha | Serum-free medium for culturing animal cells |
| US7294481B1 (en) | 1999-01-05 | 2007-11-13 | Immunex Corporation | Method for producing recombinant proteins |
| EP1757700A3 (en) | 1999-04-26 | 2009-03-11 | Genentech, Inc. | Cell culture process for glycoproteins |
| JP2003501022A (ja) | 1999-05-27 | 2003-01-14 | ファルマシア・アンド・アップジョン・カンパニー | イオンチャネルコンダクタンスを測定するための方法およびその組成物 |
| AT409379B (de) * | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
| DE60009956T2 (de) | 1999-12-28 | 2005-04-28 | Iso Tis N.V. | Wachstumsfaktoren und l-glutamin enthaltendes zellkulturmedium |
| CA2438148A1 (en) | 2001-02-15 | 2002-08-29 | Centocor, Inc. | Chemically defined medium for cultured mammalian cells |
| AU2002316230A1 (en) | 2001-06-13 | 2002-12-23 | Genentech, Inc. | Methods of culturing animal cells and polypeptide production in animal cells |
| ATE359358T1 (de) | 2002-07-15 | 2007-05-15 | Immunex Corp | Verfahren und medien zur kontrolle der sialysierung von proteinen, die von säugetierzellen produziert werden |
| WO2004058800A2 (en) | 2002-12-23 | 2004-07-15 | Bristol-Myers Squibb Company | Mammalian cell culture processes for protein production |
| GB0304799D0 (en) * | 2003-03-03 | 2003-04-09 | Glaxosmithkline Biolog Sa | Novel method |
| DE10338536A1 (de) | 2003-08-19 | 2005-04-07 | Bircher Reglomat Ag | Verfahren zum Betreiben eines Radarsensors |
| TWI384069B (zh) * | 2004-08-27 | 2013-02-01 | Pfizer Ireland Pharmaceuticals | 多胜肽之製法 |
| TWI374935B (en) | 2004-08-27 | 2012-10-21 | Pfizer Ireland Pharmaceuticals | Production of α-abeta |
| EP1707634A1 (en) | 2005-03-29 | 2006-10-04 | Octapharma AG | Method for isolation of recombinantly produced proteins |
| EP1937798A4 (en) | 2005-04-15 | 2009-05-13 | Univ Columbia | CHEMICALLY DEFINED CULTURAL MEDIA FOR THE EXPANSION AND DIFFERENTIATION OF EPIDERMIC CELLS AND USES THEREOF FOR THE IN VITRO FARMING OF HAIRFOLLICLES |
| US20070231895A1 (en) | 2005-11-02 | 2007-10-04 | Lee Gene W | Methods for adapting mammalian cells |
| US20070190057A1 (en) | 2006-01-23 | 2007-08-16 | Jian Wu | Methods for modulating mannose content of recombinant proteins |
| JP5564259B2 (ja) * | 2006-11-08 | 2014-07-30 | ワイス・エルエルシー | 細胞培養のための合理的に設計された培地 |
| DK2563904T3 (en) * | 2010-04-26 | 2015-04-07 | Novartis Ag | Improved cell culture medium |
-
2011
- 2011-04-25 DK DK11717240T patent/DK2563904T3/en active
- 2011-04-25 WO PCT/EP2011/056508 patent/WO2011134920A1/en active Application Filing
- 2011-04-25 US US13/643,998 patent/US9428727B2/en not_active Ceased
- 2011-04-25 PL PL11717240T patent/PL2563904T3/pl unknown
- 2011-04-25 AU AU2011246503A patent/AU2011246503B2/en active Active
- 2011-04-25 PT PT117172403T patent/PT2563904E/pt unknown
- 2011-04-25 EP EP11717240.3A patent/EP2563904B1/en not_active Revoked
- 2011-04-25 CA CA2797356A patent/CA2797356C/en active Active
- 2011-04-25 CN CN201180021024.XA patent/CN102858952B/zh active Active
- 2011-04-25 KR KR1020127030709A patent/KR101828623B1/ko active IP Right Grant
- 2011-04-25 JP JP2013506612A patent/JP6347949B2/ja active Active
- 2011-04-25 ES ES11717240.3T patent/ES2533074T3/es active Active
- 2011-04-25 BR BR112012027282-9A patent/BR112012027282B1/pt active IP Right Grant
- 2011-04-25 SG SG2012079174A patent/SG185038A1/en unknown
- 2011-04-25 RU RU2012150346A patent/RU2644651C2/ru active
- 2011-04-25 MX MX2012012526A patent/MX2012012526A/es active IP Right Grant
- 2011-04-25 US US16/114,731 patent/USRE48864E1/en active Active
-
2012
- 2012-10-15 IL IL222452A patent/IL222452B/en active IP Right Grant
-
2016
- 2016-08-03 JP JP2016152747A patent/JP6603628B2/ja active Active
-
2019
- 2019-08-01 JP JP2019142124A patent/JP7034991B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BR112012027282B1 (pt) | 2020-09-29 |
| JP7034991B2 (ja) | 2022-03-14 |
| EP2563904A1 (en) | 2013-03-06 |
| CA2797356C (en) | 2020-12-29 |
| EP2563904B1 (en) | 2015-01-21 |
| CN102858952B (zh) | 2015-10-14 |
| SG185038A1 (en) | 2012-11-29 |
| KR101828623B1 (ko) | 2018-02-12 |
| RU2018101201A (ru) | 2019-02-21 |
| US20130122543A1 (en) | 2013-05-16 |
| JP2013524825A (ja) | 2013-06-20 |
| AU2011246503A1 (en) | 2012-11-22 |
| DK2563904T3 (en) | 2015-04-07 |
| WO2011134920A1 (en) | 2011-11-03 |
| JP2019216728A (ja) | 2019-12-26 |
| JP6347949B2 (ja) | 2018-06-27 |
| CA2797356A1 (en) | 2011-11-03 |
| AU2011246503B2 (en) | 2013-09-26 |
| JP6603628B2 (ja) | 2019-11-06 |
| JP2017012180A (ja) | 2017-01-19 |
| BR112012027282A2 (pt) | 2015-09-22 |
| IL222452B (en) | 2019-03-31 |
| RU2644651C2 (ru) | 2018-02-13 |
| US9428727B2 (en) | 2016-08-30 |
| USRE48864E1 (en) | 2021-12-28 |
| CN102858952A (zh) | 2013-01-02 |
| PT2563904E (pt) | 2015-05-12 |
| RU2012150346A (ru) | 2014-06-10 |
| MX2012012526A (es) | 2012-11-23 |
| IL222452A0 (en) | 2012-12-31 |
| RU2018101201A3 (e) | 2021-05-27 |
| ES2533074T3 (es) | 2015-04-07 |
| KR20130058699A (ko) | 2013-06-04 |
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