PL2457919T3 - Oligosacharydy zawierające grupę aminooksylową i ich koniugaty - Google Patents

Oligosacharydy zawierające grupę aminooksylową i ich koniugaty

Info

Publication number
PL2457919T3
PL2457919T3 PL11188504T PL11188504T PL2457919T3 PL 2457919 T3 PL2457919 T3 PL 2457919T3 PL 11188504 T PL11188504 T PL 11188504T PL 11188504 T PL11188504 T PL 11188504T PL 2457919 T3 PL2457919 T3 PL 2457919T3
Authority
PL
Poland
Prior art keywords
oligosaccharides
conjugates
aminooxy group
aminooxy
group
Prior art date
Application number
PL11188504T
Other languages
English (en)
Inventor
Yunxiang Zhu
Seng H. Chen
Canwen Jiang
Luis Z. Avial
Original Assignee
Genzyme Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corporation filed Critical Genzyme Corporation
Publication of PL2457919T3 publication Critical patent/PL2457919T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/738—Cross-linked polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/04—Phosphoric diester hydrolases (3.1.4)
    • C12Y301/04012—Sphingomyelin phosphodiesterase (3.1.4.12)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0102—Alpha-glucosidase (3.2.1.20)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01022—Alpha-galactosidase (3.2.1.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01076—L-Iduronidase (3.2.1.76)
PL11188504T 2007-01-18 2008-01-18 Oligosacharydy zawierające grupę aminooksylową i ich koniugaty PL2457919T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US88547107P 2007-01-18 2007-01-18
EP08727910.5A EP2121713B1 (en) 2007-01-18 2008-01-18 Oligosaccharides comprising an aminooxy group and conjugates thereof
EP11188504.2A EP2457919B1 (en) 2007-01-18 2008-01-18 Oligosaccharides comprising an aminooxy group and conjugates thereof
PCT/US2008/051429 WO2008089403A2 (en) 2007-01-18 2008-01-18 Oligosaccharides comprising an aminooxy group and conjugates thereof

Publications (1)

Publication Number Publication Date
PL2457919T3 true PL2457919T3 (pl) 2019-12-31

Family

ID=39473250

Family Applications (3)

Application Number Title Priority Date Filing Date
PL08727910T PL2121713T3 (pl) 2007-01-18 2008-01-18 Oligosacharydy zawierające grupę aminooksylową oraz ich koniugaty
PL11188504T PL2457919T3 (pl) 2007-01-18 2008-01-18 Oligosacharydy zawierające grupę aminooksylową i ich koniugaty
PL11188506T PL2457920T3 (pl) 2007-01-18 2008-01-18 Oligosacharydy zawierające grupę aminooksylową i ich koniugaty

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL08727910T PL2121713T3 (pl) 2007-01-18 2008-01-18 Oligosacharydy zawierające grupę aminooksylową oraz ich koniugaty

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL11188506T PL2457920T3 (pl) 2007-01-18 2008-01-18 Oligosacharydy zawierające grupę aminooksylową i ich koniugaty

Country Status (19)

Country Link
US (5) US8759501B2 (pl)
EP (5) EP2457919B1 (pl)
JP (6) JP5999867B2 (pl)
CN (2) CN102978185B (pl)
CA (1) CA2675968C (pl)
CY (2) CY1119954T1 (pl)
DK (3) DK2457919T3 (pl)
ES (3) ES2656314T3 (pl)
FR (1) FR22C1061I2 (pl)
HR (3) HRP20130744T1 (pl)
HU (3) HUE045046T2 (pl)
IL (3) IL243117B2 (pl)
LT (2) LT2457920T (pl)
NL (1) NL301210I2 (pl)
NO (2) NO2457920T3 (pl)
PL (3) PL2121713T3 (pl)
PT (3) PT2457920T (pl)
SI (2) SI2457920T1 (pl)
WO (1) WO2008089403A2 (pl)

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Also Published As

Publication number Publication date
EP2457920B1 (en) 2017-10-25
JP6309592B2 (ja) 2018-04-11
US9469850B2 (en) 2016-10-18
WO2008089403A3 (en) 2008-11-13
SI2457919T1 (sl) 2019-10-30
PL2457920T3 (pl) 2018-03-30
EP3597655A1 (en) 2020-01-22
NL301210I2 (nl) 2023-02-02
IL199925A (en) 2017-09-28
JP2018109194A (ja) 2018-07-12
JP5999867B2 (ja) 2016-09-28
EP2457919A1 (en) 2012-05-30
CY1119954T1 (el) 2018-12-12
US20200010825A1 (en) 2020-01-09
EP2457920A1 (en) 2012-05-30
DK2457919T3 (da) 2019-09-16
FR22C1061I1 (fr) 2023-02-03
EP4293112A3 (en) 2024-03-13
EP4293112A2 (en) 2023-12-20
FR22C1061I2 (fr) 2023-11-17
US20170014520A1 (en) 2017-01-19
PL2121713T3 (pl) 2013-11-29
JP6039625B2 (ja) 2016-12-07
US20150050262A1 (en) 2015-02-19
ES2744574T3 (es) 2020-02-25
HRP20130744T1 (hr) 2013-10-11
LT2457920T (lt) 2018-02-12
JP2010516257A (ja) 2010-05-20
PT2121713E (pt) 2013-06-25
HUS2200055I1 (hu) 2023-01-28
NL301210I1 (nl) 2022-12-21
JP2022137232A (ja) 2022-09-21
CY1122452T1 (el) 2021-01-27
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