PL2417141T3 - Pochodne 2-hydroksyetylo-1h-chinolin-2-onu i ich analogi azaizosteryczne o działaniu przeciwbakteryjnym - Google Patents
Pochodne 2-hydroksyetylo-1h-chinolin-2-onu i ich analogi azaizosteryczne o działaniu przeciwbakteryjnymInfo
- Publication number
- PL2417141T3 PL2417141T3 PL10714481T PL10714481T PL2417141T3 PL 2417141 T3 PL2417141 T3 PL 2417141T3 PL 10714481 T PL10714481 T PL 10714481T PL 10714481 T PL10714481 T PL 10714481T PL 2417141 T3 PL2417141 T3 PL 2417141T3
- Authority
- PL
- Poland
- Prior art keywords
- quinolin
- hydroxyethyl
- derivatives
- antibacterial activity
- azaisosteric
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2009051510 | 2009-04-09 | ||
| PCT/IB2010/051517 WO2010116337A1 (en) | 2009-04-09 | 2010-04-08 | 2-hydroxyethyl-1h-quinolin-2-one derivatives and their azaisosteric analogues with antibacterial activity |
| EP10714481.8A EP2417141B1 (en) | 2009-04-09 | 2010-04-08 | 2-hydroxyethyl-1h-quinolin-2-one derivatives and their azaisosteric analogues with antibacterial activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2417141T3 true PL2417141T3 (pl) | 2014-03-31 |
Family
ID=42199672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10714481T PL2417141T3 (pl) | 2009-04-09 | 2010-04-08 | Pochodne 2-hydroksyetylo-1h-chinolin-2-onu i ich analogi azaizosteryczne o działaniu przeciwbakteryjnym |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8415375B2 (pl) |
| EP (1) | EP2417141B1 (pl) |
| JP (1) | JP5639639B2 (pl) |
| KR (1) | KR101729345B1 (pl) |
| CN (1) | CN102361875B (pl) |
| AR (1) | AR076222A1 (pl) |
| AU (1) | AU2010233387B2 (pl) |
| BR (1) | BRPI1015310A8 (pl) |
| CA (1) | CA2756727C (pl) |
| ES (1) | ES2438742T3 (pl) |
| MX (1) | MX2011010358A (pl) |
| PL (1) | PL2417141T3 (pl) |
| RU (1) | RU2540862C2 (pl) |
| TW (1) | TWI455937B (pl) |
| WO (1) | WO2010116337A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR076222A1 (es) | 2009-04-09 | 2011-05-26 | Actelion Pharmaceuticals Ltd | Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen |
| WO2013003383A1 (en) * | 2011-06-27 | 2013-01-03 | Kyorin Pharmaceutical Co., Ltd. | Bridged bicyclic compounds for the treatment of bacterial infections |
| TW201313726A (zh) | 2011-09-16 | 2013-04-01 | Actelion Pharmaceuticals Ltd | 製造合成之中間體之方法 |
| TW201833120A (zh) | 2017-02-17 | 2018-09-16 | 瑞士商愛杜西亞製藥有限公司 | 芳基噁唑啶酮抗生素化合物 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1095611A1 (ru) * | 1982-09-10 | 2007-06-27 | Краснодарский ордена Трудового Красного Знамени политехнический институт | Хлорид 5-хлорметил-2-этил-8-метил-4Н-м-диоксино-(4,5-с)-пиридиния, обладающий антимикробной активностью |
| EG20543A (en) * | 1992-10-30 | 1999-07-31 | Procter & Gamble | Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones |
| EP0934932A4 (en) * | 1996-08-22 | 2002-06-26 | Meiji Seika Kaisha | CHINOLINE DERIVATIVES AND PSYCHOTROPES MEDIUM |
| GB0112834D0 (en) * | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
| TW200406413A (en) * | 2002-06-26 | 2004-05-01 | Glaxo Group Ltd | Compounds |
| EP1796466A4 (en) | 2004-06-15 | 2009-09-02 | Glaxo Group Ltd | ANTIBACTERIAL AGENTS |
| WO2006032466A2 (en) * | 2004-09-24 | 2006-03-30 | Actelion Pharmaceuticals Ltd | New bicyclic antibiotics |
| ES2330670T3 (es) * | 2005-05-25 | 2009-12-14 | Actelion Pharmaceuticals Ltd. | Nuevos derivados antibioticos. |
| MY150958A (en) * | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| WO2006137485A1 (ja) | 2005-06-24 | 2006-12-28 | Toyama Chemical Co., Ltd. | 新規な含窒素複素環化合物およびその塩 |
| CN101341126A (zh) * | 2005-10-13 | 2009-01-07 | 莫弗凯姆联合化学股份公司 | 具有抗菌活性的5-喹啉衍生物 |
| KR101409261B1 (ko) * | 2006-05-26 | 2014-06-18 | 다이쇼 세이야꾸 가부시끼가이샤 | 신규의 복소환 화합물 또는 그 염 및 그 중간체 |
| EP1992628A1 (en) | 2007-05-18 | 2008-11-19 | Glaxo Group Limited | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones |
| WO2008071981A1 (en) | 2006-12-15 | 2008-06-19 | Astrazeneca Ab | Piperidines for the treatment of bacterial infections |
| WO2008071964A1 (en) | 2006-12-15 | 2008-06-19 | Astrazeneca Ab | Naphthyridine bactericides |
| WO2008071962A1 (en) | 2006-12-15 | 2008-06-19 | Astrazeneca Ab | Pteridines and pyrimidinopyridines as antibacterial agents |
| TW200831517A (en) | 2006-12-15 | 2008-08-01 | Astrazeneca Ab | Chemical compounds |
| MY149347A (en) | 2007-04-20 | 2013-08-30 | Glaxo Group Ltd | Tricyclic nitrogen containing compounds as antibacterial agents |
| EP2005995A1 (en) | 2007-06-22 | 2008-12-24 | Glaxo Group Limited | Heterocyclic compounds for the treatment of tuberculosis |
| WO2009001126A1 (en) | 2007-06-27 | 2008-12-31 | Astrazeneca Ab | Substituted piperidine derivatives and their use as antibaterial agents |
| GB0800367D0 (en) | 2008-01-09 | 2008-02-20 | Glaxo Group Ltd | Compounds |
| BRPI0908208A2 (pt) | 2008-02-22 | 2015-08-25 | Actelion Pharmaceuticals Ltd | Composto derivado de oxazolidinona, medicamento, composição farmacêutica que o contém e uso desse composto. |
| MX2010012855A (es) | 2008-06-03 | 2010-12-21 | Actelion Pharmaceuticals Ltd | Derivados de [4-(1-amino-etil)-ciclohexil]-metil-amina y [6-(1-amino-etil)-tetrahidro-piran-3-il]-metil-amina como antibacterianos. |
| ES2628091T3 (es) | 2008-10-10 | 2017-08-01 | Idorsia Pharmaceuticals Ltd | Antibióticos de oxazolidinilo |
| MX2011005905A (es) | 2008-12-12 | 2011-06-20 | Actelion Pharmaceuticals Ltd | Derivados de 5-amino-2-(1-hidroxi-etil)-tetrahidropirano. |
| AR076222A1 (es) | 2009-04-09 | 2011-05-26 | Actelion Pharmaceuticals Ltd | Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen |
-
2010
- 2010-04-07 AR ARP100101165A patent/AR076222A1/es unknown
- 2010-04-08 BR BRPI1015310A patent/BRPI1015310A8/pt not_active Application Discontinuation
- 2010-04-08 AU AU2010233387A patent/AU2010233387B2/en not_active Ceased
- 2010-04-08 US US13/263,922 patent/US8415375B2/en not_active Expired - Fee Related
- 2010-04-08 MX MX2011010358A patent/MX2011010358A/es active IP Right Grant
- 2010-04-08 RU RU2011145052/04A patent/RU2540862C2/ru not_active IP Right Cessation
- 2010-04-08 TW TW099110909A patent/TWI455937B/zh not_active IP Right Cessation
- 2010-04-08 PL PL10714481T patent/PL2417141T3/pl unknown
- 2010-04-08 EP EP10714481.8A patent/EP2417141B1/en not_active Not-in-force
- 2010-04-08 KR KR1020117023354A patent/KR101729345B1/ko active IP Right Grant
- 2010-04-08 CN CN201080013196.8A patent/CN102361875B/zh not_active Expired - Fee Related
- 2010-04-08 WO PCT/IB2010/051517 patent/WO2010116337A1/en active Application Filing
- 2010-04-08 ES ES10714481.8T patent/ES2438742T3/es active Active
- 2010-04-08 CA CA2756727A patent/CA2756727C/en not_active Expired - Fee Related
- 2010-04-08 JP JP2012504122A patent/JP5639639B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010233387A1 (en) | 2011-11-24 |
| CN102361875B (zh) | 2014-08-20 |
| CA2756727C (en) | 2017-05-02 |
| EP2417141B1 (en) | 2013-10-16 |
| BRPI1015310A2 (pt) | 2016-05-24 |
| KR20120014240A (ko) | 2012-02-16 |
| US20120040989A1 (en) | 2012-02-16 |
| US8415375B2 (en) | 2013-04-09 |
| CN102361875A (zh) | 2012-02-22 |
| CA2756727A1 (en) | 2010-10-14 |
| BRPI1015310A8 (pt) | 2017-12-26 |
| AR076222A1 (es) | 2011-05-26 |
| EP2417141A1 (en) | 2012-02-15 |
| RU2540862C2 (ru) | 2015-02-10 |
| JP2012523407A (ja) | 2012-10-04 |
| MX2011010358A (es) | 2011-11-01 |
| RU2011145052A (ru) | 2013-05-20 |
| WO2010116337A1 (en) | 2010-10-14 |
| KR101729345B1 (ko) | 2017-04-21 |
| AU2010233387B2 (en) | 2015-01-15 |
| TW201040182A (en) | 2010-11-16 |
| TWI455937B (zh) | 2014-10-11 |
| ES2438742T3 (es) | 2014-01-20 |
| JP5639639B2 (ja) | 2014-12-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2505173A4 (en) | ABSORBENT ARTICLE | |
| EP2409673A4 (en) | ABSORBENT ARTICLE | |
| EP2415429A4 (en) | ABSORBENT ARTICLE | |
| IL213974A0 (en) | Isoxazole-isoxazole and isoxazole-isothiazole derivatives | |
| ZA201109034B (en) | Aminopyrrolidinone derivatives and uses thereof | |
| EP2410966A4 (en) | ABSORBENT ARTICLE | |
| EP2520262A4 (en) | ABSORBENT ARTICLE | |
| ZA201201259B (en) | Nitroimidazooxazine and nitroimidazooxazole analogues and their uses | |
| PL2246017T3 (pl) | Artykuł chłonny | |
| HK1221478A1 (zh) | 變體及其用途 | |
| HK1160756A1 (en) | Absorbent article | |
| EP2623502A4 (en) | NEW CONNECTION WITH STRIGOLACTON EFFECT AND USE THEREOF | |
| EP2412354A4 (en) | CLEANABLE UNDERWEAR | |
| EP2523689A4 (en) | IL-22-FC WITH HEPCIDINE EFFECT | |
| ZA201108577B (en) | Cellulase variants with improved expression, activity and/or stability, and use thereof | |
| ZA201200860B (en) | New macrolides and their use | |
| HK1178526A1 (en) | Tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof 8--7- | |
| EP2412344A4 (en) | ABSORBENT ARTICLE | |
| IL226220A0 (en) | Preparations with antibacterial activity and wound healing activity | |
| GB0902173D0 (en) | Compounds and their use | |
| PL2417141T3 (pl) | Pochodne 2-hydroksyetylo-1h-chinolin-2-onu i ich analogi azaizosteryczne o działaniu przeciwbakteryjnym | |
| EP2386278A4 (en) | VOIDABLE ARTICLE | |
| GB0915372D0 (en) | Absorbent article with improved adherence | |
| EP2484322A4 (en) | ABSORBENT ARTICLE | |
| GB0922510D0 (en) | Compound and use |