PL2400968T3 - Kompozycje, synteza i sposoby zastosowania pochodnych arylopiperazyny - Google Patents

Kompozycje, synteza i sposoby zastosowania pochodnych arylopiperazyny

Info

Publication number
PL2400968T3
PL2400968T3 PL10746949T PL10746949T PL2400968T3 PL 2400968 T3 PL2400968 T3 PL 2400968T3 PL 10746949 T PL10746949 T PL 10746949T PL 10746949 T PL10746949 T PL 10746949T PL 2400968 T3 PL2400968 T3 PL 2400968T3
Authority
PL
Poland
Prior art keywords
synthesis
compositions
methods
arylpiperazine derivatives
utilizing
Prior art date
Application number
PL10746949T
Other languages
English (en)
Polish (pl)
Inventor
Laxminarayan Bhat
Prabhu Prasad Mohapatra
Kouacou Adiey
Original Assignee
Reviva Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reviva Pharmaceuticals, Inc. filed Critical Reviva Pharmaceuticals, Inc.
Publication of PL2400968T3 publication Critical patent/PL2400968T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
PL10746949T 2009-02-26 2010-02-26 Kompozycje, synteza i sposoby zastosowania pochodnych arylopiperazyny PL2400968T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15579109P 2009-02-26 2009-02-26

Publications (1)

Publication Number Publication Date
PL2400968T3 true PL2400968T3 (pl) 2017-04-28

Family

ID=42631516

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10746949T PL2400968T3 (pl) 2009-02-26 2010-02-26 Kompozycje, synteza i sposoby zastosowania pochodnych arylopiperazyny

Country Status (24)

Country Link
US (9) US8575185B2 (enExample)
EP (1) EP2400968B1 (enExample)
JP (1) JP5337259B2 (enExample)
KR (1) KR101705727B1 (enExample)
CN (2) CN102413830A (enExample)
AU (1) AU2010217772B2 (enExample)
BR (1) BRPI1009757B1 (enExample)
CA (1) CA2753599C (enExample)
CO (1) CO6430428A2 (enExample)
DK (1) DK2400968T3 (enExample)
ES (1) ES2605232T3 (enExample)
HU (1) HUE031053T2 (enExample)
IL (1) IL214754A (enExample)
MX (1) MX2011008885A (enExample)
MY (1) MY161473A (enExample)
NZ (1) NZ595263A (enExample)
PH (1) PH12011501669B1 (enExample)
PL (1) PL2400968T3 (enExample)
PT (1) PT2400968T (enExample)
RU (1) RU2506262C2 (enExample)
SG (1) SG173842A1 (enExample)
UA (1) UA102730C2 (enExample)
WO (2) WO2010099502A1 (enExample)
ZA (1) ZA201106805B (enExample)

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CN102413830A (zh) * 2009-02-26 2012-04-11 雷维瓦药品公司 利用芳基哌嗪衍生物的组合物、合成及方法
KR101571670B1 (ko) * 2012-08-08 2015-11-25 주식회사 씨엠지제약 아리피프라졸을 포함하는 경구용 속용 필름 제제
WO2015157451A1 (en) 2014-04-08 2015-10-15 Reviva Pharmaceuticals, Inc. Methods for treating attention deficit hyperactivity disorder
EP3244896B1 (en) * 2015-01-12 2024-06-12 Reviva Pharmaceuticals, Inc. Methods for treating pulmonary hypertension
EP3244898A4 (en) * 2015-01-12 2018-08-22 Reviva Pharmaceuticals, Inc. Methods for treating psychosis associated with parkinson's disease
EP3244897A4 (en) * 2015-01-12 2018-08-22 Reviva Pharmaceuticals, Inc. Methods for treating alzheimer's disease
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WO2017042837A2 (en) * 2015-09-11 2017-03-16 Sun Pharmaceutical Industries Limited Stable crystalline form of regadenoson
CN113912586B (zh) 2016-08-31 2023-04-07 江苏恒瑞医药股份有限公司 氧代吡啶酰胺类衍生物、其制备方法及其在医药上的应用
EP3749324B1 (en) 2017-12-28 2025-11-05 Reviva Pharmaceuticals, Inc. Arylpiperazine compound for use to treat pulmonary fibrosis
CN112618580A (zh) * 2020-12-30 2021-04-09 北京科拓恒通生物技术股份有限公司 鼠李糖乳杆菌Probio-M9及其制品用于制备治疗自闭症药物的用途
US20250214980A1 (en) 2022-03-14 2025-07-03 Slap Pharmaceuticals Llc Multicyclic compounds
CN120882702A (zh) 2023-01-07 2025-10-31 亚细亚化学工业有限公司 布瑞拉沙秦和布瑞拉沙秦盐的固态形式
CN121013714A (zh) * 2023-03-30 2025-11-25 雷维瓦药品公司 布瑞拉沙秦脂质体组合物
CN118026945A (zh) * 2024-01-24 2024-05-14 武汉工程大学 一种布瑞拉沙秦的合成方法

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Also Published As

Publication number Publication date
JP5337259B2 (ja) 2013-11-06
HK1167240A1 (zh) 2012-11-23
WO2010099502A1 (en) 2010-09-02
US20100216783A1 (en) 2010-08-26
CO6430428A2 (es) 2012-04-30
US20120220574A1 (en) 2012-08-30
KR20120013306A (ko) 2012-02-14
US8461154B2 (en) 2013-06-11
ES2605232T3 (es) 2017-03-13
AU2010217772A1 (en) 2011-10-20
CN102413830A (zh) 2012-04-11
DK2400968T3 (da) 2017-01-02
US20100222359A1 (en) 2010-09-02
US9255076B2 (en) 2016-02-09
US20170327477A1 (en) 2017-11-16
PH12011501669B1 (en) 2014-02-13
UA102730C2 (uk) 2013-08-12
MY161473A (en) 2017-04-14
HUE031053T2 (en) 2017-06-28
CA2753599C (en) 2017-03-14
US8980883B2 (en) 2015-03-17
US20150166493A1 (en) 2015-06-18
CA2753599A1 (en) 2010-09-02
IL214754A0 (en) 2011-11-30
MX2011008885A (es) 2011-09-29
WO2010099503A1 (en) 2010-09-02
US8188076B2 (en) 2012-05-29
JP2012519182A (ja) 2012-08-23
US20120220579A1 (en) 2012-08-30
AU2010217772B2 (en) 2014-10-23
EP2400968B1 (en) 2016-09-28
US9604944B2 (en) 2017-03-28
SG173842A1 (en) 2011-09-29
EP2400968A4 (en) 2012-08-01
US8575185B2 (en) 2013-11-05
RU2506262C2 (ru) 2014-02-10
US20150005298A1 (en) 2015-01-01
KR101705727B1 (ko) 2017-02-10
CN106045936A (zh) 2016-10-26
NZ595263A (en) 2013-06-28
US9975862B2 (en) 2018-05-22
ZA201106805B (en) 2013-02-27
EP2400968A1 (en) 2012-01-04
RU2011139154A (ru) 2013-04-10
US8431570B2 (en) 2013-04-30
IL214754A (en) 2014-05-28
US8859552B2 (en) 2014-10-14
BRPI1009757A2 (pt) 2016-03-15
PT2400968T (pt) 2016-12-09
US20160229821A1 (en) 2016-08-11
BRPI1009757B1 (pt) 2020-01-14
US20140155392A1 (en) 2014-06-05

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