PL2297297T3 - Wytwarzanie kwasu bursztynowego przez fermentację w niskim pH - Google Patents
Wytwarzanie kwasu bursztynowego przez fermentację w niskim pHInfo
- Publication number
- PL2297297T3 PL2297297T3 PL09779520T PL09779520T PL2297297T3 PL 2297297 T3 PL2297297 T3 PL 2297297T3 PL 09779520 T PL09779520 T PL 09779520T PL 09779520 T PL09779520 T PL 09779520T PL 2297297 T3 PL2297297 T3 PL 2297297T3
- Authority
- PL
- Poland
- Prior art keywords
- fermentation
- low
- succinic acid
- acid production
- production
- Prior art date
Links
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 title 2
- 230000004151 fermentation Effects 0.000 title 1
- 238000000855 fermentation Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000001384 succinic acid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
- C12Y103/01006—Fumarate reductase (NADH) (1.3.1.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/05—Oxidoreductases acting on the CH-CH group of donors (1.3) with a quinone or related compound as acceptor (1.3.5)
- C12Y103/05004—Fumarate reductase (menaquinone) (1.3.5.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01032—Phosphoenolpyruvate carboxykinase (GTP) (4.1.1.32)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01038—Phosphoenolpyruvate carboxykinase (diphosphate) (4.1.1.38)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01049—Phosphoenolpyruvate carboxykinase (ATP) (4.1.1.49)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01002—Fumarate hydratase (4.2.1.2)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08159891 | 2008-07-08 | ||
| EP09779520.7A EP2297297B1 (en) | 2008-07-08 | 2009-05-20 | Succinic acid production by fermentation at low ph |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2297297T3 true PL2297297T3 (pl) | 2017-08-31 |
Family
ID=40329358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09779520T PL2297297T3 (pl) | 2008-07-08 | 2009-05-20 | Wytwarzanie kwasu bursztynowego przez fermentację w niskim pH |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9012187B2 (pl) |
| EP (2) | EP3176265A1 (pl) |
| CN (3) | CN107267562A (pl) |
| BR (1) | BRPI0915534B1 (pl) |
| CA (1) | CA2730595C (pl) |
| EA (1) | EA018463B1 (pl) |
| ES (1) | ES2623932T3 (pl) |
| PL (1) | PL2297297T3 (pl) |
| UA (1) | UA103033C2 (pl) |
| WO (1) | WO2010003728A1 (pl) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107267562A (zh) * | 2008-07-08 | 2017-10-20 | 帝斯曼知识产权资产管理有限公司 | 通过在低pH下发酵生产二羧酸 |
| WO2010118932A1 (en) * | 2009-04-15 | 2010-10-21 | Dsm Ip Assets B.V. | Dicarboxylic acid production process |
| US20120156761A1 (en) | 2009-07-02 | 2012-06-21 | Verdezyne, Inc. | Biological methods for preparing adipic acid |
| US8741611B2 (en) | 2009-09-01 | 2014-06-03 | Novozymes, Inc. | Methods for improving malic acid production in filamentous fungi |
| JP5857954B2 (ja) * | 2010-03-09 | 2016-02-10 | 三菱化学株式会社 | コハク酸の製造方法 |
| JP5754785B2 (ja) | 2010-03-26 | 2015-07-29 | バイオアンバー インコーポレイテッド | コハク酸二アンモニウム、コハク酸一アンモニウム及び／又はコハク酸を含む発酵培地からコハク酸一アンモニウムの製造、及びコハク酸一アンモニウムからコハク酸への変換方法 |
| US8410291B2 (en) | 2010-04-01 | 2013-04-02 | BioAmber International S.á.r.l. | Processes for the production of hydrogenated products |
| US8399687B2 (en) | 2010-04-01 | 2013-03-19 | Bioamber International S.A.R.L. | Processes for the production of hydrogenated products |
| US20110269993A1 (en) | 2010-04-30 | 2011-11-03 | Bioamber S.A.S. | Processes for producing adipic acid from fermentation broths containing diammonium adipate |
| US8895779B2 (en) | 2010-04-30 | 2014-11-25 | Bioamber Inc. | Processes for producing monoammonium adipate and conversion of monoammonium adipate to adipic acid |
| DK2576606T3 (en) | 2010-06-04 | 2015-02-23 | Novozymes Inc | Preparation of C4 dicarboxylic acid in filamentous fungi |
| JP2013530184A (ja) | 2010-06-16 | 2013-07-25 | ビオアンブ，ソシエテ パ アクシオンス シンプリフィエ | ヘキサメチレンジアミン（ｈｍｄ）、アジポニトリル（ａｄｎ）、アジパミド（ａｄｍ）及びそれらの誘導体の製造方法 |
| BR112012031877A2 (pt) | 2010-06-16 | 2015-09-22 | Bioamber Sas | processo para produzir caprolactam e derivados do mesmo de caldos de fermentação contendo adipato de diamônio ou adipato de monomônio. |
| BR112012031818A2 (pt) | 2010-06-16 | 2019-09-24 | Bioamber Sas | processos para a produção de produtos hidrogenados e derivados dos mesmos. |
| CA2800291A1 (en) | 2010-06-16 | 2011-12-22 | Bioamber S.A.S. | Processes for producing caprolactam and derivatives thereof from fermentation broths containing diammonium adipate, monoammonium adipate and/or adipic acid |
| BR112012031822A2 (pt) | 2010-06-16 | 2015-09-22 | Bioamber Sas | processos para a produção de produtos hidrogenados e seus derivados. |
| CN103140467A (zh) | 2010-06-16 | 2013-06-05 | 生物琥珀酸有限公司 | 己二胺（hmd）、己二腈（adn）、己二酰胺（adm）及其衍生物的制备方法 |
| US8158395B2 (en) | 2010-06-21 | 2012-04-17 | Novozymes, Inc. | Polypeptides having C4 dicarboxylic acid transporter activity and polynucleotides encoding same |
| WO2011163270A1 (en) | 2010-06-21 | 2011-12-29 | Novozymes, Inc. | Methods for improved c4-dicarboxylic acid production in filamentous fungi |
| BR112013006883A2 (pt) * | 2010-09-24 | 2016-06-07 | Dsm Ip Assets Bv | processo de produção de ácido dicarboxílico |
| US9605285B2 (en) | 2011-01-25 | 2017-03-28 | Cargill, Incorporated | Compositions and methods for succinate production |
| EP2681307A1 (en) | 2011-02-28 | 2014-01-08 | Novozymes, Inc. | Microorganism for c4-dicarboxylic acid production |
| US8728798B2 (en) | 2011-05-03 | 2014-05-20 | Verdezyne, Inc. | Biological methods for preparing adipic acid |
| US8343752B2 (en) | 2011-05-03 | 2013-01-01 | Verdezyne, Inc. | Biological methods for preparing adipic acid |
| WO2012170060A1 (en) | 2011-06-10 | 2012-12-13 | Bioamber S.A.S. | Processes for producing hexanediol (hdo), hexamethylenediamine (hmd), and derivatives thereof |
| CN103917649A (zh) | 2011-08-19 | 2014-07-09 | 诺维信股份有限公司 | 用于生产c4-二羧酸的重组微生物 |
| DE102011056297A1 (de) * | 2011-12-12 | 2013-06-13 | Thyssenkrupp Uhde Gmbh | Verfahren zur biotechnischen Herstellung von Dicarbonsäuren |
| WO2013112939A2 (en) * | 2012-01-25 | 2013-08-01 | Cargill, Incorporated | Methods for succinate production |
| US9850507B2 (en) | 2012-07-25 | 2017-12-26 | Cargill, Incorporated | Yeast cells having reductive TCA pathway from pyruvate to succinate and overexpressing an exogenous NAD(P)+ transhydrogenase enzyme |
| KR102253532B1 (ko) | 2012-09-14 | 2021-05-18 | 피티티 글로벌 케미컬 퍼블릭 컴퍼니 리미티드 | 낮은 ph에서 발효에 의한 유기산의 제조 |
| EP2898018A4 (en) | 2012-09-17 | 2016-07-20 | Ndsu Res Foundation | BLOCKED BIO-BASED CARBOXYLIC ACIDS AND THEIR USE IN HEAT-CURABLE MATERIALS |
| CN118652942A (zh) | 2013-07-18 | 2024-09-17 | 德希尼布能源法国公司 | 发酵方法 |
| EA037088B1 (ru) * | 2013-12-12 | 2021-02-04 | ДСМ АйПи АССЕТС Б.В. | Фумаратредуктазы |
| EP3365427B1 (en) | 2015-10-23 | 2020-08-19 | Metabolic Explorer | Microorganism modified for the assimilation of levulinic acid |
| ES2899973T3 (es) * | 2016-07-13 | 2022-03-15 | Dsm Ip Assets Bv | Malato deshidrogenasas |
| WO2019005340A1 (en) | 2017-06-30 | 2019-01-03 | Myriant Corporation | GENETICALLY MODIFIED YEAST HAVING INCREASED PRODUCTION OF SUCCINIC ACID |
| CN110218746A (zh) * | 2018-03-01 | 2019-09-10 | 上海凯赛生物技术研发中心有限公司 | 发酵生产长链二元酸的方法及发酵液、发酵处理液、污水 |
| KR102129379B1 (ko) | 2018-10-10 | 2020-07-02 | 한국과학기술원 | 고활성의 말산 탈수소효소가 도입된 숙신산 생성용 변이 미생물 및 이를 이용한 숙신산 제조방법 |
| CN115947809B (zh) * | 2022-11-02 | 2025-05-02 | 杭州宝晶生物股份有限公司 | 一种苹果酸转运蛋白突变体及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4877731A (en) | 1988-06-27 | 1989-10-31 | E. I. Du Pont De Nemours And Company | Fermentation process for carboxylic acids |
| US5573931A (en) | 1995-08-28 | 1996-11-12 | Michigan Biotechnology Institute | Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants |
| US5869301A (en) | 1995-11-02 | 1999-02-09 | Lockhead Martin Energy Research Corporation | Method for the production of dicarboxylic acids |
| US6475759B1 (en) * | 1997-10-14 | 2002-11-05 | Cargill, Inc. | Low PH lactic acid fermentation |
| BR0010806B1 (pt) * | 1999-05-21 | 2014-02-18 | Métodos e materiais para a síntese de produtos orgânicos | |
| WO2003102201A2 (en) | 2002-05-30 | 2003-12-11 | Cargill Dow Llc | Methods and materials for the production of d-lactic acid in yeast |
| JP4647391B2 (ja) * | 2005-05-20 | 2011-03-09 | 財団法人地球環境産業技術研究機構 | コリネ型細菌による高効率なジカルボン酸の製造方法 |
| DE102005052338A1 (de) * | 2005-07-19 | 2007-05-16 | Leibniz Inst Naturstoff Forsch | Verfahren zur Herstellung von methylierten Malonsäuren durch mikrobielle Fermentation |
| US20080090273A1 (en) | 2005-11-21 | 2008-04-17 | Aaron Adriaan Winkler | Malic Acid Production in Recombinant Yeast |
| EP2001992B1 (en) | 2006-03-13 | 2016-07-20 | Cargill Inc. | Yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol |
| JP5250850B2 (ja) | 2006-06-29 | 2013-07-31 | ディーエスエム アイピー アセッツ ビー．ブイ． | 改善されたポリペプチド発現を達成する方法 |
| EP2158323A4 (en) * | 2007-05-18 | 2011-06-22 | Microbia Prec Engineering Inc | PRODUCTION OF ORGANIC ACID BY PILZ CELLS |
| WO2008144626A1 (en) * | 2007-05-18 | 2008-11-27 | Microbia Precision Engineering, Inc. | Malic acid production in recombinant yeast |
| EP2687602A1 (en) | 2007-11-20 | 2014-01-22 | DSM IP Assets B.V. | Succinic acid production in a eukaryotic cell |
| CN107267562A (zh) * | 2008-07-08 | 2017-10-20 | 帝斯曼知识产权资产管理有限公司 | 通过在低pH下发酵生产二羧酸 |
-
2009
- 2009-05-20 CN CN201710244247.1A patent/CN107267562A/zh active Pending
- 2009-05-20 BR BRPI0915534-1A patent/BRPI0915534B1/pt active IP Right Grant
- 2009-05-20 EP EP16206648.4A patent/EP3176265A1/en not_active Withdrawn
- 2009-05-20 CN CN201710243972.7A patent/CN107267561A/zh active Pending
- 2009-05-20 CA CA2730595A patent/CA2730595C/en active Active
- 2009-05-20 CN CN2009801269436A patent/CN102089436A/zh active Pending
- 2009-05-20 PL PL09779520T patent/PL2297297T3/pl unknown
- 2009-05-20 EP EP09779520.7A patent/EP2297297B1/en active Active
- 2009-05-20 WO PCT/EP2009/056181 patent/WO2010003728A1/en not_active Ceased
- 2009-05-20 UA UAA201101388A patent/UA103033C2/ru unknown
- 2009-05-20 EA EA201100156A patent/EA018463B1/ru not_active IP Right Cessation
- 2009-05-20 US US13/003,217 patent/US9012187B2/en active Active
- 2009-05-20 ES ES09779520.7T patent/ES2623932T3/es active Active
-
2015
- 2015-03-19 US US14/662,594 patent/US9340805B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20110229945A1 (en) | 2011-09-22 |
| CN107267562A (zh) | 2017-10-20 |
| CA2730595C (en) | 2014-12-16 |
| CN102089436A (zh) | 2011-06-08 |
| UA103033C2 (ru) | 2013-09-10 |
| WO2010003728A4 (en) | 2010-04-08 |
| ES2623932T3 (es) | 2017-07-12 |
| WO2010003728A1 (en) | 2010-01-14 |
| EA018463B1 (ru) | 2013-08-30 |
| CN107267561A (zh) | 2017-10-20 |
| US20150232891A1 (en) | 2015-08-20 |
| EP3176265A1 (en) | 2017-06-07 |
| EA201100156A1 (ru) | 2011-08-30 |
| CA2730595A1 (en) | 2010-01-14 |
| BRPI0915534B1 (pt) | 2021-04-20 |
| EP2297297A1 (en) | 2011-03-23 |
| US9340805B2 (en) | 2016-05-17 |
| US9012187B2 (en) | 2015-04-21 |
| EP2297297B1 (en) | 2017-02-08 |
| BRPI0915534A2 (pt) | 2020-08-18 |
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