PL2206498T3 - Mieszani agoniści ORL1/µ do leczenia bólu - Google Patents

Mieszani agoniści ORL1/µ do leczenia bólu

Info

Publication number
PL2206498T3
PL2206498T3 PL10003202T PL10003202T PL2206498T3 PL 2206498 T3 PL2206498 T3 PL 2206498T3 PL 10003202 T PL10003202 T PL 10003202T PL 10003202 T PL10003202 T PL 10003202T PL 2206498 T3 PL2206498 T3 PL 2206498T3
Authority
PL
Poland
Prior art keywords
orl1
receptor
agonist
pain
agonists
Prior art date
Application number
PL10003202T
Other languages
English (en)
Inventor
Klaus Linz
Babette-Yvonne Kögel
Wolfgang Schröder
Thomas Christoph
Vry Jean De
Elmar Friderichs
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of PL2206498T3 publication Critical patent/PL2206498T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
PL10003202T 2006-09-29 2007-09-26 Mieszani agoniści ORL1/µ do leczenia bólu PL2206498T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102006046745A DE102006046745A1 (de) 2006-09-29 2006-09-29 Gemischte ORL1/µ-Agonisten zur Behandlung von Schmerz
EP07818462A EP2081571B1 (de) 2006-09-29 2007-09-26 GEMISCHTE ORL1/µ -AGONISTEN ZUR BEHANDLUNG VON SCHMERZ
EP10003202A EP2206498B9 (de) 2006-09-29 2007-09-26 Gemischte ORL1/µ-Agonisten zur Behandlung von Schmerz

Publications (1)

Publication Number Publication Date
PL2206498T3 true PL2206498T3 (pl) 2012-04-30

Family

ID=38982475

Family Applications (2)

Application Number Title Priority Date Filing Date
PL07818462T PL2081571T3 (pl) 2006-09-29 2007-09-26 Mieszane substancje antagonistyczne ORL 1/µ do zwalczania bólów
PL10003202T PL2206498T3 (pl) 2006-09-29 2007-09-26 Mieszani agoniści ORL1/µ do leczenia bólu

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL07818462T PL2081571T3 (pl) 2006-09-29 2007-09-26 Mieszane substancje antagonistyczne ORL 1/µ do zwalczania bólów

Country Status (13)

Country Link
US (3) US20080125475A1 (pl)
EP (2) EP2081571B1 (pl)
JP (2) JP5203373B2 (pl)
AT (2) ATE478667T1 (pl)
CA (1) CA2664702C (pl)
CY (2) CY1110879T1 (pl)
DE (2) DE102006046745A1 (pl)
DK (2) DK2206498T3 (pl)
ES (2) ES2377482T3 (pl)
PL (2) PL2081571T3 (pl)
PT (2) PT2206498E (pl)
SI (2) SI2081571T1 (pl)
WO (1) WO2008040481A1 (pl)

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WO2009118174A1 (de) 2008-03-27 2009-10-01 Grünenthal GmbH Substituierte cyclohexyldiamine
BR122013017393A2 (pt) 2008-03-27 2019-10-15 Grünenthal GmbH Compostos derivados substituídos de 4-aminociclohexano, medicamentos contendo pelo menos um composto e uso dos referidos compostos
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SI2809320T1 (sl) * 2012-02-03 2017-07-31 Gruenenthal Gmbh (1r,4r)-6'-fluoro-(N-metil- ali N,N-dimetil-)-4-fenil-4',9'-dihidro-3'H -spiro(cikloheksan-1,1'-pirano(3,4,b)indol)-4-amin za zdravljenje fibromialgije in sindroma kronične utrujenosti
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US9855286B2 (en) 2012-05-18 2018-01-02 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component
US9320725B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a gabapentinoid
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US9308196B2 (en) * 2012-05-18 2016-04-12 Gruenenthal Gmbh Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam
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PL3110797T3 (pl) 2014-02-27 2019-11-29 Gruenenthal Gmbh Proces otrzymywania 5-fluorotryptofolu
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Also Published As

Publication number Publication date
WO2008040481A1 (de) 2008-04-10
CY1110879T1 (el) 2015-06-10
DE102006046745A1 (de) 2008-04-03
JP5203373B2 (ja) 2013-06-05
PL2081571T3 (pl) 2011-02-28
EP2206498B9 (de) 2012-04-18
JP2013116907A (ja) 2013-06-13
CA2664702C (en) 2016-08-09
PT2206498E (pt) 2012-02-15
ATE542532T1 (de) 2012-02-15
ATE478667T1 (de) 2010-09-15
PT2081571E (pt) 2010-11-29
CY1112471T1 (el) 2015-12-09
US20150342929A1 (en) 2015-12-03
DK2206498T3 (da) 2012-03-19
JP5698282B2 (ja) 2015-04-08
US20080125475A1 (en) 2008-05-29
EP2206498B1 (de) 2012-01-25
SI2081571T1 (sl) 2010-12-31
DE502007004875D1 (de) 2010-10-07
ES2351528T3 (es) 2011-02-07
EP2206498A1 (de) 2010-07-14
US20110015220A1 (en) 2011-01-20
EP2081571B1 (de) 2010-08-25
SI2206498T1 (sl) 2012-03-30
DK2081571T3 (da) 2010-11-08
CA2664702A1 (en) 2008-04-10
EP2081571A1 (de) 2009-07-29
JP2010504926A (ja) 2010-02-18
ES2377482T3 (es) 2012-03-28

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