PL2183273T3 - Cykliczne depsypeptydy - Google Patents

Cykliczne depsypeptydy

Info

Publication number
PL2183273T3
PL2183273T3 PL08803036T PL08803036T PL2183273T3 PL 2183273 T3 PL2183273 T3 PL 2183273T3 PL 08803036 T PL08803036 T PL 08803036T PL 08803036 T PL08803036 T PL 08803036T PL 2183273 T3 PL2183273 T3 PL 2183273T3
Authority
PL
Poland
Prior art keywords
cyclic depsipeptides
depsipeptides
cyclic
Prior art date
Application number
PL08803036T
Other languages
English (en)
Inventor
Philipp Krastel
Brigitta-Maria Liechty
Josef Gottfried Meingassner
Esther Schmitt
Erwin Paul Schreiner
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38805728&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2183273(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2183273T3 publication Critical patent/PL2183273T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL08803036T 2007-08-17 2008-08-14 Cykliczne depsypeptydy PL2183273T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07114507 2007-08-17

Publications (1)

Publication Number Publication Date
PL2183273T3 true PL2183273T3 (pl) 2017-09-29

Family

ID=38805728

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08803036T PL2183273T3 (pl) 2007-08-17 2008-08-14 Cykliczne depsypeptydy

Country Status (30)

Country Link
US (2) US8178650B2 (pl)
EP (1) EP2183273B1 (pl)
JP (1) JP5520824B2 (pl)
KR (2) KR20120123579A (pl)
CN (1) CN103298827B (pl)
AR (1) AR068343A1 (pl)
AU (1) AU2008290567B2 (pl)
BR (1) BRPI0815547B8 (pl)
CA (1) CA2696570C (pl)
CL (1) CL2008002394A1 (pl)
CO (1) CO6260099A2 (pl)
CR (1) CR11251A (pl)
CU (2) CU23943B1 (pl)
EA (1) EA017735B1 (pl)
EC (1) ECSP109968A (pl)
ES (1) ES2632392T3 (pl)
GT (1) GT201000037A (pl)
MA (1) MA31701B1 (pl)
MX (1) MX2010001849A (pl)
MY (1) MY151973A (pl)
NZ (1) NZ583284A (pl)
PE (2) PE20141199A1 (pl)
PL (1) PL2183273T3 (pl)
PT (1) PT2183273T (pl)
SV (1) SV2010003485A (pl)
TN (1) TN2010000074A1 (pl)
TW (1) TW200922613A (pl)
UA (1) UA98658C2 (pl)
WO (1) WO2009024527A1 (pl)
ZA (1) ZA201000776B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY151973A (en) 2007-08-17 2014-07-31 Novartis Ag Cyclic depsipeptides
US8415305B2 (en) 2007-08-17 2013-04-09 Novartis Ag Use of cyclic depsipeptides to inhibit kallikrein 7
US20120034650A1 (en) * 2009-02-13 2012-02-09 Novartis Ag Nucleic acid molecule of a biosynthetic cluster encoding non ribosomal peptide synthases and uses thereof
US8680054B2 (en) * 2011-04-20 2014-03-25 Novartis Ag Suspension type topical formulations comprising cyclic depsipeptide
US8614289B2 (en) 2011-04-20 2013-12-24 Novartis Ag Processes for the manufacture of macrocyclic depsipeptides and new intermediates
US8987413B2 (en) 2012-10-09 2015-03-24 Novartis Ag Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates
US9067978B2 (en) 2012-10-09 2015-06-30 Novartis Ag Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates
AU2015209759B2 (en) 2014-01-23 2018-11-29 Sixera Pharma Ab New kallikrein 7 inhibitors
WO2015114144A1 (en) * 2014-02-03 2015-08-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of netherton syndrome
WO2015155676A1 (en) 2014-04-08 2015-10-15 Novartis Ag Novel aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates
KR101729848B1 (ko) 2015-06-30 2017-04-24 영남대학교 산학협력단 신규한 해양 바실러스속 균주, 이로부터 분리한 화합물 및 상기 화합물의 약제학적 용도
CN106518880B (zh) * 2015-11-04 2018-10-19 衡阳师范学院 激肽释放酶7小分子抑制剂及其制备方法与用途
US11643438B2 (en) 2018-07-20 2023-05-09 The Board Of Regents Of The University Of Oklahoma Antimicrobial peptides and methods of use

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3043252C2 (de) 1980-11-15 1982-12-02 Degussa Ag, 6000 Frankfurt Cyclische Acetale von N-Acylglutaminsäure -γ- semialdehyden, Verfahren zu deren Herstellung und ihre Verwendung
US5595756A (en) 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
DE4421113A1 (de) * 1994-06-16 1995-12-21 Biotechnolog Forschung Gmbh Chondramide, Gewinnungsverfahren, Mittel mit Chondramiden und Mischkultur zur Chondramid-Gewinnung
DE19828043A1 (de) 1998-06-24 1999-12-30 Bayer Ag Ektoparasitizide Mittel
JP2000154198A (ja) 1998-11-20 2000-06-06 Nisshin Flour Milling Co Ltd 環状デプシペプチドの固相合成方法及びその中間体
GB0108234D0 (en) 2001-04-02 2001-05-23 Pharma Mar Sa Process for producing trunkamide A compounds
US20040110228A1 (en) 2002-04-01 2004-06-10 Mcalpine Shelli R. Combinatorial organic synthesis of unique biologically active compounds
US7872052B2 (en) 2003-06-06 2011-01-18 Arexis Ab Use of heterocyclic compounds as SCCE inhibitors
GB0322140D0 (en) 2003-09-22 2003-10-22 Pfizer Ltd Combinations
WO2005075667A1 (en) * 2004-02-03 2005-08-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with kallikrein 7 (klk7)
AU2007220042A1 (en) * 2006-02-27 2007-09-07 Arizona Board Of Regents For And On Behalf Of Arizona State University Identification and use of novopeptides for the treatment of cancer
US8415305B2 (en) 2007-08-17 2013-04-09 Novartis Ag Use of cyclic depsipeptides to inhibit kallikrein 7
MY151973A (en) 2007-08-17 2014-07-31 Novartis Ag Cyclic depsipeptides
US20110112121A1 (en) 2009-07-06 2011-05-12 Joerg Berghausen Pharmaceutical Compositions and Solid Forms
US20120064013A1 (en) 2010-02-03 2012-03-15 David Marcos Foamable topical composition
KR101004362B1 (ko) 2010-03-19 2010-12-28 가톨릭대학교 산학협력단 자가 면역 질환 예방 및 치료용 ＴＮＦ－α와 ＴＷＥＡＫ 이중 길항제
US20120064136A1 (en) 2010-09-10 2012-03-15 Nanobio Corporation Anti-aging and wrinkle treatment methods using nanoemulsion compositions
US8673974B2 (en) 2010-11-16 2014-03-18 Novartis Ag Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
EP2667859A2 (en) 2011-01-24 2013-12-04 Anterios, Inc. Nanoparticle compositions, formulations thereof, and uses therefor
DK2667854T3 (en) 2011-01-24 2019-04-23 Anterios Inc NANO PARTICLE FORMATIONS
US8614289B2 (en) 2011-04-20 2013-12-24 Novartis Ag Processes for the manufacture of macrocyclic depsipeptides and new intermediates
US8680054B2 (en) 2011-04-20 2014-03-25 Novartis Ag Suspension type topical formulations comprising cyclic depsipeptide
US8987413B2 (en) 2012-10-09 2015-03-24 Novartis Ag Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates
US9067978B2 (en) 2012-10-09 2015-06-30 Novartis Ag Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates

Also Published As

Publication number Publication date
TW200922613A (en) 2009-06-01
CU20130063A7 (es) 2013-06-28
CN103298827B (zh) 2017-05-31
PE20141199A1 (es) 2014-09-24
ES2632392T3 (es) 2017-09-12
BRPI0815547B8 (pt) 2021-05-25
CU20100032A7 (es) 2011-10-05
TN2010000074A1 (en) 2011-09-26
EP2183273A1 (en) 2010-05-12
AR068343A1 (es) 2009-11-11
MY151973A (en) 2014-07-31
CA2696570C (en) 2020-12-29
CN103298827A (zh) 2013-09-11
CU23943B1 (es) 2013-09-27
KR101227231B1 (ko) 2013-01-28
CA2696570A1 (en) 2009-02-26
US8178650B2 (en) 2012-05-15
WO2009024527A1 (en) 2009-02-26
US9127044B2 (en) 2015-09-08
EA017735B1 (ru) 2013-02-28
EA201000329A1 (ru) 2010-08-30
UA98658C2 (uk) 2012-06-11
US20090156472A1 (en) 2009-06-18
NZ583284A (en) 2012-04-27
US20120196790A1 (en) 2012-08-02
AU2008290567B2 (en) 2011-05-12
JP5520824B2 (ja) 2014-06-11
MX2010001849A (es) 2010-03-10
AU2008290567A1 (en) 2009-02-26
BRPI0815547B1 (pt) 2020-09-15
ECSP109968A (es) 2010-03-31
CR11251A (es) 2010-03-08
MA31701B1 (fr) 2010-09-01
KR20100044893A (ko) 2010-04-30
CL2008002394A1 (es) 2009-05-15
PT2183273T (pt) 2017-05-22
PE20091007A1 (es) 2009-08-14
BRPI0815547A2 (pt) 2015-02-10
SV2010003485A (es) 2011-03-23
ZA201000776B (en) 2010-10-27
GT201000037A (es) 2012-04-30
JP2010536731A (ja) 2010-12-02
EP2183273B1 (en) 2017-04-05
CO6260099A2 (es) 2011-03-22
KR20120123579A (ko) 2012-11-08

Similar Documents

Publication Publication Date Title
ZA201000776B (en) Cyclic depsipeptides
IL219048A (en) Peptide compounds derived from urcl10
AU321420S (en) Pedometer
IL199623A0 (en) An arrangement
GB2460685B (en) An inclusive chair
GB0713598D0 (en) Cyclic ethers
IL201485A0 (en) New cyclic peptide compounds
GB0723712D0 (en) Peptides
GB0920981D0 (en) Peptides
EP2123666A4 (en) PEPTIDE
GB0803054D0 (en) Medicament
HK1142342A1 (en) Cyclic, cystein-free protein
EP2358740A4 (en) CYCLIC PEPTIDES AND USES THEREOF
EP2060563A4 (en) CYCLIC AMINOALKYLCARBOXAMIDE DERIVATIVE
GB0723387D0 (en) Improved dehumldifier
AU316472S (en) Cannula
EP2370100A4 (en) PEPTIDE AGENTS
GB0703945D0 (en) Peptide
GB0920987D0 (en) Peptides
EP2134587A4 (en) INTERMEDIATE TRACTION BAR ARRANGEMENT
GB0717450D0 (en) Medicament
GB0708529D0 (en) Peptide standards
GB0817978D0 (en) Peptides
GB0806180D0 (en) Improved structure
GB0705115D0 (en) Peptides