PL2041138T3 - Pirolotriazyny jako inhibitory kinazy - Google Patents

Pirolotriazyny jako inhibitory kinazy

Info

Publication number
PL2041138T3
PL2041138T3 PL07799265T PL07799265T PL2041138T3 PL 2041138 T3 PL2041138 T3 PL 2041138T3 PL 07799265 T PL07799265 T PL 07799265T PL 07799265 T PL07799265 T PL 07799265T PL 2041138 T3 PL2041138 T3 PL 2041138T3
Authority
PL
Poland
Prior art keywords
kinase inhibitors
pyrrolotriazine kinase
pyrrolotriazine
inhibitors
kinase
Prior art date
Application number
PL07799265T
Other languages
English (en)
Inventor
Harold Mastalerz
Mark D Wittman
Kurt Zimmermann
Mark G Saulnier
Upender Velaparthi
Dolatrai M Vyas
Guifen Zhang
Walter Lewis Johnson
David B Frennesson
Xiaopeng Sang
Peiying Liu
David R Langley
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PL2041138T3 publication Critical patent/PL2041138T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
PL07799265T 2006-07-07 2007-07-03 Pirolotriazyny jako inhibitory kinazy PL2041138T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81917106P 2006-07-07 2006-07-07
EP07799265.9A EP2041138B1 (en) 2006-07-07 2007-07-03 Pyrrolotriazine kinase inhibitors
PCT/US2007/072697 WO2008005956A2 (en) 2006-07-07 2007-07-03 Pyrrolotriazine kinase inhibitors

Publications (1)

Publication Number Publication Date
PL2041138T3 true PL2041138T3 (pl) 2014-11-28

Family

ID=38671050

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07799265T PL2041138T3 (pl) 2006-07-07 2007-07-03 Pirolotriazyny jako inhibitory kinazy

Country Status (26)

Country Link
US (4) US7534792B2 (pl)
EP (1) EP2041138B1 (pl)
JP (1) JP5185930B2 (pl)
KR (1) KR101443400B1 (pl)
CN (1) CN101511835B (pl)
AR (1) AR061873A1 (pl)
AU (1) AU2007269163B2 (pl)
BR (1) BRPI0714359A2 (pl)
CA (1) CA2657594C (pl)
CL (1) CL2007001995A1 (pl)
CO (1) CO6220940A2 (pl)
DK (1) DK2041138T3 (pl)
EA (1) EA018322B1 (pl)
ES (1) ES2493566T3 (pl)
HR (1) HRP20140688T1 (pl)
IL (1) IL196033A0 (pl)
MX (1) MX2008016517A (pl)
NO (1) NO342385B1 (pl)
NZ (1) NZ574189A (pl)
PE (1) PE20080677A1 (pl)
PL (1) PL2041138T3 (pl)
PT (1) PT2041138E (pl)
SI (1) SI2041138T1 (pl)
TW (1) TWI393722B (pl)
WO (1) WO2008005956A2 (pl)
ZA (1) ZA200900109B (pl)

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US8198438B2 (en) * 2007-04-18 2012-06-12 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
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CN102015719A (zh) * 2008-03-06 2011-04-13 百时美施贵宝公司 吡咯并三嗪激酶抑制剂
UY32146A (es) 2008-09-29 2010-04-30 Boehringer Ingelheim Int Derivados de las 5-[4-(1,5-dimetil-1h-pirazol-4-il)-1,2,3-triazol-1-il]-6-metil-nicotinamidas n-(sustituidas) y de las n-{5-[4-(1,5-dimetil-1h-pirazol-4-il)-1,2,3-triazol-1-il]-6-metil-piridin-3-il}-benzamidas sustituidas y composiciones conteniéndolos
WO2010042684A1 (en) * 2008-10-08 2010-04-15 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
ES2539620T3 (es) 2008-12-19 2015-07-02 Cephalon, Inc. Pirrolotriazina como inhibidor de ALK y de JAK2
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CN102725294B (zh) * 2010-02-03 2015-09-02 百时美施贵宝公司 (s)-1-(4-(5-环丙基-1h-吡唑-3-基氨基)吡咯并[1,2-f][1,2,4]三嗪-2-基)-n-(6-氟吡啶-3-基)-2-甲基吡咯烷-2-甲酰胺的晶型
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BRPI0714359A2 (pt) * 2006-07-07 2013-02-26 Bristol-Myers Squibb Company inibidores de pirrolotriazina cinase
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Also Published As

Publication number Publication date
US20110124623A1 (en) 2011-05-26
EP2041138A2 (en) 2009-04-01
CN101511835B (zh) 2013-11-27
AU2007269163B2 (en) 2011-07-28
IL196033A0 (en) 2009-09-01
EP2041138B1 (en) 2014-06-25
US7879855B2 (en) 2011-02-01
CL2007001995A1 (es) 2008-01-25
KR101443400B1 (ko) 2014-10-02
WO2008005956A3 (en) 2008-03-06
US20090239838A1 (en) 2009-09-24
CA2657594A1 (en) 2008-01-10
JP5185930B2 (ja) 2013-04-17
NZ574189A (en) 2011-03-31
EA018322B1 (ru) 2013-07-30
US8592579B2 (en) 2013-11-26
TW200813059A (en) 2008-03-16
US20080009497A1 (en) 2008-01-10
JP2009542814A (ja) 2009-12-03
EA200900152A1 (ru) 2009-06-30
US20120302747A1 (en) 2012-11-29
SI2041138T1 (sl) 2014-08-29
MX2008016517A (es) 2009-01-19
CO6220940A2 (es) 2010-11-19
NO20090025L (no) 2009-02-02
PT2041138E (pt) 2014-10-07
ES2493566T3 (es) 2014-09-12
HRP20140688T1 (hr) 2014-10-24
DK2041138T3 (da) 2014-08-11
BRPI0714359A2 (pt) 2013-02-26
AR061873A1 (es) 2008-09-24
NO342385B1 (no) 2018-05-14
WO2008005956A2 (en) 2008-01-10
CN101511835A (zh) 2009-08-19
US7534792B2 (en) 2009-05-19
ZA200900109B (en) 2010-03-31
AU2007269163A1 (en) 2008-01-10
TWI393722B (zh) 2013-04-21
CA2657594C (en) 2012-01-17
US8263765B2 (en) 2012-09-11
PE20080677A1 (es) 2008-06-26
KR20090027764A (ko) 2009-03-17

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