PL2034015T3 - Immunostymulujący oligonukleotyd i jego zastosowanie farmaceutyczne - Google Patents
Immunostymulujący oligonukleotyd i jego zastosowanie farmaceutyczneInfo
- Publication number
- PL2034015T3 PL2034015T3 PL07744493T PL07744493T PL2034015T3 PL 2034015 T3 PL2034015 T3 PL 2034015T3 PL 07744493 T PL07744493 T PL 07744493T PL 07744493 T PL07744493 T PL 07744493T PL 2034015 T3 PL2034015 T3 PL 2034015T3
- Authority
- PL
- Poland
- Prior art keywords
- immunostimulatory oligonucleotide
- pharmaceutical application
- pharmaceutical
- application
- immunostimulatory
- Prior art date
Links
- 108091034117 Oligonucleotide Proteins 0.000 title 1
- 230000003308 immunostimulating effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Transplantation (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006152544 | 2006-05-31 | ||
| JP2007046556 | 2007-02-27 | ||
| EP07744493A EP2034015B1 (en) | 2006-05-31 | 2007-05-31 | Immunostimulatory oligonucleotide and pharmaceutical application thereof |
| PCT/JP2007/061105 WO2007139190A1 (ja) | 2006-05-31 | 2007-05-31 | 免疫刺激オリゴヌクレオチド及びその医薬用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2034015T3 true PL2034015T3 (pl) | 2012-11-30 |
Family
ID=38778707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07744493T PL2034015T3 (pl) | 2006-05-31 | 2007-05-31 | Immunostymulujący oligonukleotyd i jego zastosowanie farmaceutyczne |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8592566B2 (pl) |
| EP (1) | EP2034015B1 (pl) |
| JP (1) | JP5161770B2 (pl) |
| KR (1) | KR101065760B1 (pl) |
| CN (1) | CN101460620B (pl) |
| AU (1) | AU2007268534B2 (pl) |
| CA (1) | CA2653939C (pl) |
| DK (1) | DK2034015T3 (pl) |
| ES (1) | ES2389112T3 (pl) |
| PL (1) | PL2034015T3 (pl) |
| WO (1) | WO2007139190A1 (pl) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004238139B2 (en) * | 2003-05-15 | 2009-12-03 | Japan Science And Technology Agency | Immunostimulating Agents |
| CN102282155B (zh) | 2008-12-02 | 2017-06-09 | 日本波涛生命科学公司 | 磷原子修饰的核酸的合成方法 |
| KR101885383B1 (ko) | 2009-07-06 | 2018-08-03 | 웨이브 라이프 사이언시스 리미티드 | 신규한 핵산 프로드러그 및 그의 사용 방법 |
| WO2011040535A1 (ja) | 2009-09-30 | 2011-04-07 | 東レ株式会社 | C型肝炎ウイルスワクチン組成物 |
| SI2575878T1 (sl) * | 2010-05-28 | 2018-12-31 | Zoetis Belgium S.A. | Cepiva, ki obsegajo holesterol in cpg kot edine molekule, ki nosijo adjuvans |
| WO2012039448A1 (ja) | 2010-09-24 | 2012-03-29 | 株式会社キラルジェン | 不斉補助基 |
| BR112013012195A2 (pt) * | 2010-11-16 | 2018-07-10 | Selecta Biosciences Inc | oligonucleotídeo imunoestimulatórios |
| US9605019B2 (en) | 2011-07-19 | 2017-03-28 | Wave Life Sciences Ltd. | Methods for the synthesis of functionalized nucleic acids |
| SG10201912895PA (en) | 2012-07-13 | 2020-02-27 | Wave Life Sciences Ltd | Chiral control |
| AU2013288048A1 (en) | 2012-07-13 | 2015-01-22 | Wave Life Sciences Ltd. | Asymmetric auxiliary group |
| KR101835401B1 (ko) | 2012-07-13 | 2018-03-08 | 신 니뽄 바이오메디칼 라보라토리즈, 엘티디. | 키랄 핵산 어쥬번트 |
| WO2015108047A1 (ja) | 2014-01-15 | 2015-07-23 | 株式会社新日本科学 | 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤 |
| JPWO2015108046A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 抗アレルギー作用を有するキラル核酸アジュバンド及び抗アレルギー剤 |
| EP3095459A4 (en) | 2014-01-15 | 2017-08-23 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having antitumor effect and antitumor agent |
| JP6382344B2 (ja) | 2014-01-16 | 2018-08-29 | ウェイブ ライフ サイエンシズ リミテッドWave Life Sciences Ltd. | キラルデザイン |
| US11268098B2 (en) | 2014-12-25 | 2022-03-08 | National Institutes Of Biomedical Innovation, Health And Nutrition | Non-aggregating immunostimulatory oligonucleotides |
| MA43072A (fr) | 2015-07-22 | 2018-05-30 | Wave Life Sciences Ltd | Compositions d'oligonucléotides et procédés associés |
| CN118909014A (zh) * | 2023-07-21 | 2024-11-08 | 南京吉盛澳玛生物医药有限公司 | 具有调节机体免疫能力的CpG寡聚脱氧核苷酸及其应用 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0315711A (ja) | 1989-03-14 | 1991-01-24 | Kazuko Mizogami | 距離測定用標識棒 |
| JPH0458179A (ja) | 1990-06-26 | 1992-02-25 | Mazda Motor Corp | 障害物検出装置 |
| JPH04352724A (ja) | 1990-07-27 | 1992-12-07 | Mitsui Toatsu Chem Inc | 免疫調節型治療剤 |
| EP0468520A3 (en) | 1990-07-27 | 1992-07-01 | Mitsui Toatsu Chemicals, Inc. | Immunostimulatory remedies containing palindromic dna sequences |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| CA2560114A1 (en) | 1994-07-15 | 1996-02-01 | The University Of Iowa Research Foundation | Immunomodulatory oligonucleotides |
| JP4359654B2 (ja) * | 1996-01-30 | 2009-11-04 | ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア | 抗原特異的免疫応答を生起させる遺伝子発現ベクターおよびその使用方法 |
| JP3130799B2 (ja) | 1996-06-28 | 2001-01-31 | 川崎重工業株式会社 | 発電方法及び装置 |
| EP0986572B2 (en) | 1997-06-06 | 2007-06-13 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof |
| PT1009413E (pt) | 1997-09-05 | 2007-05-31 | Univ California | Utilização de oligonucleótidos imumoestimulantes para a prevenção ou tratamento da asma. |
| JP3669845B2 (ja) | 1998-08-25 | 2005-07-13 | 株式会社タカラ | 人形体の製造方法 |
| US6977245B2 (en) * | 1999-04-12 | 2005-12-20 | The United States Of America As Represented By The Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| AU4343700A (en) | 1999-04-12 | 2000-11-14 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Oligodeoxynucleotide and its use to induce an immune response |
| MXPA02003059A (es) * | 1999-09-27 | 2002-09-30 | Univ Iowa Res Found | Metodos relacionados con interferon inducido por acido nucleico inmunoestabilizador. |
| US6949520B1 (en) | 1999-09-27 | 2005-09-27 | Coley Pharmaceutical Group, Inc. | Methods related to immunostimulatory nucleic acid-induced interferon |
| KR100359753B1 (ko) | 1999-12-21 | 2002-11-09 | 주식회사 제넥신 | 면역조절능력 및 안전성이 증가되고 dG 연속서열이결합된 포스포다이에스터 CpG올리고데옥시뉴클레오티드 변형체 |
| US7585847B2 (en) * | 2000-02-03 | 2009-09-08 | Coley Pharmaceutical Group, Inc. | Immunostimulatory nucleic acids for the treatment of asthma and allergy |
| US20020098199A1 (en) | 2000-03-10 | 2002-07-25 | Gary Van Nest | Methods of suppressing hepatitis virus infection using immunomodulatory polynucleotide sequences |
| JP2003015711A (ja) | 2001-07-03 | 2003-01-17 | Yaskawa Electric Corp | ドライブシステムのプログラム更新方法 |
| CN1604795B (zh) | 2001-08-17 | 2010-05-26 | 科勒制药股份公司 | 具有提高的活性的组合基序免疫刺激寡肽 |
| JP2004058179A (ja) | 2002-07-25 | 2004-02-26 | Nippon Densan Corp | 電解加工用電極工具 |
| MXPA05004588A (es) * | 2002-10-29 | 2005-12-14 | Coley Pharmaceutical Group Ltd | Metodos y productos relacionados con el tratamiento y prevencion de infeccion de virus de hepatitis c. |
| CN101693890B (zh) | 2002-12-23 | 2012-09-05 | 戴纳伐克斯技术股份有限公司 | 免疫刺激序列寡核苷酸和使用方法 |
| MXPA05007652A (es) * | 2003-01-16 | 2006-02-22 | Hybridon Inc | Modulacion de propiedades inmunoestimulantes de compuestos basados en oligonucleotido mediante la utilizacion de dinucleotidos inmunoestimulantes modificados. |
| JP2004287102A (ja) | 2003-03-20 | 2004-10-14 | Fuji Xerox Co Ltd | 画像形成方法 |
| WO2005001055A2 (en) * | 2003-06-11 | 2005-01-06 | Hybridon, Inc. | Stabilized immunomodulatory oligonucleotides |
| JP2005014110A (ja) | 2003-06-23 | 2005-01-20 | Daishowa Seiki Co Ltd | 押圧装置 |
| CA2544240A1 (en) | 2003-07-22 | 2005-02-17 | Cytos Biotechnology Ag | Cpg-packaged liposomes |
| JP3976742B2 (ja) | 2004-02-27 | 2007-09-19 | 江守商事株式会社 | インターフェロンアルファを誘導する免疫刺激オリゴヌクレオチド |
| JP2006035939A (ja) | 2004-07-23 | 2006-02-09 | Denso Corp | 電気ヒータ |
| JP2008000001A (ja) | 2004-09-30 | 2008-01-10 | Osaka Univ | 免疫刺激オリゴヌクレオチドおよびその医薬用途 |
-
2007
- 2007-05-31 PL PL07744493T patent/PL2034015T3/pl unknown
- 2007-05-31 AU AU2007268534A patent/AU2007268534B2/en not_active Ceased
- 2007-05-31 KR KR1020087029105A patent/KR101065760B1/ko not_active Expired - Fee Related
- 2007-05-31 ES ES07744493T patent/ES2389112T3/es active Active
- 2007-05-31 EP EP07744493A patent/EP2034015B1/en not_active Not-in-force
- 2007-05-31 US US12/301,746 patent/US8592566B2/en not_active Expired - Fee Related
- 2007-05-31 DK DK07744493.3T patent/DK2034015T3/da active
- 2007-05-31 JP JP2008517983A patent/JP5161770B2/ja not_active Expired - Fee Related
- 2007-05-31 CA CA2653939A patent/CA2653939C/en not_active Expired - Fee Related
- 2007-05-31 CN CN2007800200966A patent/CN101460620B/zh not_active Expired - Fee Related
- 2007-05-31 WO PCT/JP2007/061105 patent/WO2007139190A1/ja active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| DK2034015T3 (da) | 2012-10-15 |
| JPWO2007139190A1 (ja) | 2009-10-15 |
| CN101460620B (zh) | 2012-02-15 |
| AU2007268534B2 (en) | 2011-07-14 |
| WO2007139190A1 (ja) | 2007-12-06 |
| CN101460620A (zh) | 2009-06-17 |
| EP2034015B1 (en) | 2012-07-11 |
| ES2389112T3 (es) | 2012-10-23 |
| EP2034015A1 (en) | 2009-03-11 |
| EP2034015A4 (en) | 2010-03-17 |
| JP5161770B2 (ja) | 2013-03-13 |
| CA2653939A1 (en) | 2007-12-06 |
| KR101065760B1 (ko) | 2011-09-19 |
| KR20090018798A (ko) | 2009-02-23 |
| CA2653939C (en) | 2013-01-22 |
| US20090263413A1 (en) | 2009-10-22 |
| AU2007268534A1 (en) | 2007-12-06 |
| US8592566B2 (en) | 2013-11-26 |
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