PL1900362T3 - Pochodne alfa-aminoamidu użyteczne w leczeniu zaburzeń uzależnieniowych - Google Patents

Pochodne alfa-aminoamidu użyteczne w leczeniu zaburzeń uzależnieniowych

Info

Publication number
PL1900362T3
PL1900362T3 PL07022078T PL07022078T PL1900362T3 PL 1900362 T3 PL1900362 T3 PL 1900362T3 PL 07022078 T PL07022078 T PL 07022078T PL 07022078 T PL07022078 T PL 07022078T PL 1900362 T3 PL1900362 T3 PL 1900362T3
Authority
PL
Poland
Prior art keywords
treatment
alfa
addictive disorders
derivatives useful
aminoamide derivatives
Prior art date
Application number
PL07022078T
Other languages
English (en)
Inventor
Claudia Besana
Elena Barbanti
Emanuela Izzo
Florian Thaler
Ruggero Fariello
Patricia Salvati
Luca Benatti
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Publication of PL1900362T3 publication Critical patent/PL1900362T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
PL07022078T 2004-04-22 2005-04-19 Pochodne alfa-aminoamidu użyteczne w leczeniu zaburzeń uzależnieniowych PL1900362T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04009532A EP1588704A1 (en) 2004-04-22 2004-04-22 Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
EP05736365A EP1737438B1 (en) 2004-04-22 2005-04-19 Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome
EP07022078A EP1900362B1 (en) 2004-04-22 2005-04-19 Alfa-aminoamide derivatives useful in the treatment of addictive disorders

Publications (1)

Publication Number Publication Date
PL1900362T3 true PL1900362T3 (pl) 2011-06-30

Family

ID=34924693

Family Applications (2)

Application Number Title Priority Date Filing Date
PL07022078T PL1900362T3 (pl) 2004-04-22 2005-04-19 Pochodne alfa-aminoamidu użyteczne w leczeniu zaburzeń uzależnieniowych
PL05736365T PL1737438T3 (pl) 2004-04-22 2005-04-19 Pochodne Alfa-aminoamidu użyteczne do leczenia zespołu niespokojnych nóg

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL05736365T PL1737438T3 (pl) 2004-04-22 2005-04-19 Pochodne Alfa-aminoamidu użyteczne do leczenia zespołu niespokojnych nóg

Country Status (25)

Country Link
US (2) US8445513B2 (pl)
EP (3) EP1588704A1 (pl)
JP (1) JP5020069B2 (pl)
KR (2) KR101238377B1 (pl)
CN (1) CN1942179B (pl)
AT (2) ATE494890T1 (pl)
AU (1) AU2005235428B2 (pl)
BR (2) BRPI0509976B8 (pl)
CA (1) CA2563674C (pl)
CY (2) CY1108494T1 (pl)
DE (2) DE602005009162D1 (pl)
DK (2) DK1900362T3 (pl)
ES (2) ES2357559T3 (pl)
HR (2) HRP20080593T3 (pl)
IL (1) IL178732A (pl)
ME (2) ME02324B (pl)
MX (1) MXPA06012163A (pl)
NO (2) NO337900B1 (pl)
NZ (1) NZ550664A (pl)
PL (2) PL1900362T3 (pl)
PT (2) PT1900362E (pl)
RS (2) RS50667B (pl)
RU (1) RU2403030C2 (pl)
SI (2) SI1737438T1 (pl)
WO (1) WO2005102300A1 (pl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
JP4350508B2 (ja) 2001-09-03 2009-10-21 ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー ガバペンチンまたはその類似体とα−アミノアミドとを含む薬剤組成物およびその鎮痛用途
EP1438956A1 (en) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
WO2005018627A1 (en) * 2003-08-25 2005-03-03 Newron Pharmaceuticals, Spa Alpha-aminoamide derivatives useful as anti-inflammatory agents
EP1588704A1 (en) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
SI1809271T1 (sl) * 2004-09-10 2010-10-29 Newron Pharm Spa Uporaba (R)-(halobenziloksi) benzilamino propanamidov kot selektivnih modulatorjev natrijevih in/ali kalcijevih kanalov
JP2008519811A (ja) * 2004-11-10 2008-06-12 オリオン コーポレーション 下肢静止不能症候群の治療
NZ567540A (en) 2005-12-22 2010-07-30 Newron Pharm Spa 2-Phenylethylamino derivatives as calcium and/or sodium channel modulators
US8946300B2 (en) 2006-04-03 2015-02-03 Teva Pharmaceutical Industries, Ltd. Use of rasagilline for the treatment of restless legs syndrome
EP1870097A1 (en) 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
EA017123B1 (ru) * 2006-06-19 2012-10-30 Ньюрон Фармасьютикалс С.П.А. Способ получения 2-[4-(3- и 2-фторбензилокси)бензиламино]пропанамидов
GB0706630D0 (en) * 2007-04-04 2007-05-16 Glaxo Group Ltd Novel compounds
RS56780B1 (sr) 2007-06-15 2018-04-30 Newron Pharm Spa Substituisani derivati 2-[2-(fenil) etilamino]alkanamida i njihova upotreba kao modulatora kanala za natrijum i/ili kalcijum
KR101709498B1 (ko) 2007-12-11 2017-02-23 뉴론 파마슈티칼즈 에스. 피. 에이. 고순도의 ２­［４­（３­ 또는 ２­플루오로벤질옥시）벤질아미노］프로판아미드의 제조방법
BRPI0821026A2 (pt) * 2007-12-19 2015-06-16 Newron Pharmaceutical S P A Derivados de alfa-minoamidas úteis no tratamento de transtornos psiquiátricos
EP2314569A1 (en) 2009-10-22 2011-04-27 Merck Patent GmbH Novel polymorphic forms of (S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propionamide mesylate salt and processes of manufacturing thereof
CA2794389C (en) 2010-04-27 2016-08-23 Newron Pharmaceuticals S.P.A. Process for the production of ralfinamide methanesulfonate salts or their r-enantiomers
US11278651B2 (en) 2018-10-17 2022-03-22 Gambro Lundia Ab Membrane and device for treating restless leg syndrome
CN114667963B (zh) * 2020-12-24 2024-04-26 中国科学院脑科学与智能技术卓越创新中心 一种非人灵长类动物药物成瘾性评估的装置

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GB1140748A (en) 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
US4049663A (en) * 1972-06-06 1977-09-20 Allen & Hanburys Limited Ethylene diamine derivatives
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
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EP0331620B1 (de) * 1988-03-01 1993-08-11 Birkmayer, Walther, Prof. Dr. Mittel zur Behandlung des Parkinson-Syndroms
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
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EP1588704A1 (en) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders

Also Published As

Publication number Publication date
ES2357559T3 (es) 2011-04-27
KR101238377B1 (ko) 2013-03-04
HK1099216A1 (en) 2007-08-10
DK1900362T3 (da) 2011-05-09
CA2563674A1 (en) 2005-11-03
NO20064732L (no) 2006-11-22
PL1737438T3 (pl) 2009-01-30
CA2563674C (en) 2012-12-18
BRPI0509976B8 (pt) 2021-05-25
NO337900B1 (no) 2016-07-04
RU2403030C2 (ru) 2010-11-10
WO2005102300A1 (en) 2005-11-03
EP1900362B1 (en) 2011-01-12
ATE494890T1 (de) 2011-01-15
IL178732A (en) 2013-01-31
CY1111656T1 (el) 2015-10-07
BRPI0509976A (pt) 2007-10-16
EP1900362A3 (en) 2009-04-01
JP5020069B2 (ja) 2012-09-05
ES2313330T3 (es) 2009-03-01
HRP20110230T1 (hr) 2011-04-30
EP1900362A2 (en) 2008-03-19
DE602005009162D1 (de) 2008-10-02
CY1108494T1 (el) 2014-04-09
US8445513B2 (en) 2013-05-21
CN1942179A (zh) 2007-04-04
ATE405256T1 (de) 2008-09-15
JP2007533691A (ja) 2007-11-22
US20070203182A1 (en) 2007-08-30
ME02324B (me) 2016-06-20
RS50667B (sr) 2010-06-30
RS51791B (sr) 2011-12-31
MXPA06012163A (es) 2007-01-17
AU2005235428B2 (en) 2010-03-18
US20130217747A1 (en) 2013-08-22
SI1737438T1 (sl) 2008-12-31
NZ550664A (en) 2010-08-27
IL178732A0 (en) 2007-05-15
EP1588704A1 (en) 2005-10-26
PT1737438E (pt) 2008-12-22
BR122020004541B1 (pt) 2021-11-09
NO20150971L (no) 2006-11-22
KR101195819B1 (ko) 2012-11-05
EP1737438A1 (en) 2007-01-03
RU2006137079A (ru) 2008-04-27
EP1737438B1 (en) 2008-08-20
NO338870B1 (no) 2016-10-31
ME01219B (me) 2013-06-20
DK1737438T3 (da) 2008-12-08
KR20070042914A (ko) 2007-04-24
US8697738B2 (en) 2014-04-15
KR20120028399A (ko) 2012-03-22
PT1900362E (pt) 2011-03-09
AU2005235428A1 (en) 2005-11-03
CN1942179B (zh) 2010-08-11
SI1900362T1 (sl) 2011-03-31
BRPI0509976B1 (pt) 2020-10-06
DE602005025941D1 (de) 2011-02-24
HRP20080593T3 (en) 2008-12-31

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