PL1888537T3 - Sposób otrzymywania 4-[(1,6-dihydro-6-okso-2-pirymidynylo)amino benzonitrylu - Google Patents

Sposób otrzymywania 4-[(1,6-dihydro-6-okso-2-pirymidynylo)amino benzonitrylu

Info

Publication number
PL1888537T3
PL1888537T3 PL06755299T PL06755299T PL1888537T3 PL 1888537 T3 PL1888537 T3 PL 1888537T3 PL 06755299 T PL06755299 T PL 06755299T PL 06755299 T PL06755299 T PL 06755299T PL 1888537 T3 PL1888537 T3 PL 1888537T3
Authority
PL
Poland
Prior art keywords
pyrimidinyl
dihydro
oxo
preparing
amino benzonitrile
Prior art date
Application number
PL06755299T
Other languages
English (en)
Polish (pl)
Inventor
Didier Philippe Robert Schils
Alfred Elisabeth Stappers
Original Assignee
Janssen Sciences Ireland Uc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35822492&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1888537(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Sciences Ireland Uc filed Critical Janssen Sciences Ireland Uc
Publication of PL1888537T3 publication Critical patent/PL1888537T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL06755299T 2005-05-26 2006-05-24 Sposób otrzymywania 4-[(1,6-dihydro-6-okso-2-pirymidynylo)amino benzonitrylu PL1888537T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP05104531 2005-05-26
US68599305P 2005-05-31 2005-05-31
PCT/EP2006/062606 WO2006125809A1 (en) 2005-05-26 2006-05-24 Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl)amino benzonitrile
EP06755299.2A EP1888537B1 (en) 2005-05-26 2006-05-24 Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl)amino benzonitrile

Publications (1)

Publication Number Publication Date
PL1888537T3 true PL1888537T3 (pl) 2014-02-28

Family

ID=35822492

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06755299T PL1888537T3 (pl) 2005-05-26 2006-05-24 Sposób otrzymywania 4-[(1,6-dihydro-6-okso-2-pirymidynylo)amino benzonitrylu

Country Status (19)

Country Link
US (2) US8101752B2 (en, 2012)
EP (1) EP1888537B1 (en, 2012)
JP (2) JP5148483B2 (en, 2012)
CN (1) CN101248051B (en, 2012)
AU (1) AU2006251163C1 (en, 2012)
BR (1) BRPI0611038B8 (en, 2012)
CA (1) CA2609716C (en, 2012)
DK (1) DK1888537T3 (en, 2012)
ES (1) ES2437202T3 (en, 2012)
HR (1) HRP20131133T1 (en, 2012)
IN (1) IN2014DN04588A (en, 2012)
ME (1) ME01612B (en, 2012)
MX (1) MX2007014881A (en, 2012)
PL (1) PL1888537T3 (en, 2012)
PT (1) PT1888537E (en, 2012)
RS (1) RS53062B (en, 2012)
RU (1) RU2458056C2 (en, 2012)
SI (1) SI1888537T1 (en, 2012)
WO (1) WO2006125809A1 (en, 2012)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2458056C2 (ru) * 2005-05-26 2012-08-10 Тиботек Фармасьютикалз Лтд Способ получения 4-(1,6-дигидро-6-оксо-2-пиримидинил)амино-бензонитрила
WO2012125993A1 (en) 2011-03-17 2012-09-20 Teva Pharmaceutical Industries Ltd. Solid state forms of rilpivirine base, and rilipivirine salts
AU2013231321B2 (en) 2012-03-13 2017-05-25 Octapharma Ag Improved process for production of fibrinogen and fibrinogen produced thereby
CN103058936B (zh) * 2013-01-23 2016-01-06 宁波九胜创新医药科技有限公司 4-[(4-氯-2-嘧啶基)氨基]苯腈的制备方法
CN103193719B (zh) * 2013-04-08 2015-07-22 宁波九胜创新医药科技有限公司 一种4-[(4-羟基-2-嘧啶基)氨基]苯腈的制备方法
CN114933567B (zh) * 2022-04-29 2023-07-11 武汉工程大学 一种2-甲硫基-4-嘧啶酮的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63502B1 (en) * 1989-04-21 1995-05-03 Zeneca Ltd Aminopyrimidine derivatives useful for treating cardiovascular disorders
DE3923979A1 (de) 1989-07-20 1991-01-24 Merck Patent Gmbh Verfahren zur herstellung von aromatischen nitrilen
RU2037483C1 (ru) * 1989-07-20 1995-06-19 Мерк Патент Гмбх Способ получения замещенных ароматических нитрилов
TR200002760T2 (tr) * 1998-03-27 2000-12-21 Janssen Pharmaceutica N.V. HIV engelleyici pirimidin türevleri
WO2000027825A1 (en) * 1998-11-10 2000-05-18 Janssen Pharmaceutica N.V. Hiv replication inhibiting pyrimidines
PL207590B1 (pl) * 1999-09-24 2011-01-31 Janssen Pharmaceutica Nv Cząstka stanowiąca dyspersję stałą oraz postać dawkowania, sposób ich otrzymywania i zastosowanie
ES2559273T3 (es) * 2000-05-08 2016-02-11 Janssen Pharmaceutica Nv Profármacos de pirimidinas que inhiben la replicación del VIH
JO3429B1 (ar) * 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
CN100491371C (zh) * 2001-11-01 2009-05-27 詹森药业有限公司 用作糖原合酶激酶3β抑制剂(GSK3抑制剂)的杂芳胺化合物
CN101481356B (zh) * 2002-08-09 2012-07-11 詹森药业有限公司 制备4-[[4-[[4-(2-氰基乙烯基)-2,6-二甲基苯基]氨基]-2-嘧啶基]氨基]苄腈的方法
CA2540704A1 (en) * 2003-09-30 2005-05-19 Janssen Pharmaceutica N.V. Benzoimidazole compounds
RU2458056C2 (ru) * 2005-05-26 2012-08-10 Тиботек Фармасьютикалз Лтд Способ получения 4-(1,6-дигидро-6-оксо-2-пиримидинил)амино-бензонитрила

Also Published As

Publication number Publication date
RU2007148968A (ru) 2009-07-10
JP5580385B2 (ja) 2014-08-27
JP2013040194A (ja) 2013-02-28
SI1888537T1 (sl) 2014-01-31
US8618291B2 (en) 2013-12-31
AU2006251163B2 (en) 2012-03-08
HK1123551A1 (en) 2009-06-19
AU2006251163A1 (en) 2006-11-30
IN2014DN04588A (en, 2012) 2015-07-10
HRP20131133T1 (hr) 2014-01-03
EP1888537B1 (en) 2013-09-11
US20080171878A1 (en) 2008-07-17
DK1888537T3 (da) 2013-12-09
EP1888537A1 (en) 2008-02-20
ES2437202T3 (es) 2014-01-09
JP5148483B2 (ja) 2013-02-20
PT1888537E (pt) 2013-11-26
CA2609716A1 (en) 2006-11-30
RU2458056C2 (ru) 2012-08-10
CN101248051A (zh) 2008-08-20
US20120083606A1 (en) 2012-04-05
BRPI0611038B8 (pt) 2022-10-25
CA2609716C (en) 2014-10-14
JP2008545680A (ja) 2008-12-18
US8101752B2 (en) 2012-01-24
MX2007014881A (es) 2008-02-15
BRPI0611038B1 (pt) 2022-02-08
WO2006125809A1 (en) 2006-11-30
AU2006251163C1 (en) 2012-07-12
BRPI0611038A2 (pt) 2010-08-10
RS53062B (en) 2014-04-30
CN101248051B (zh) 2013-07-17
ME01612B (me) 2014-09-20

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