PL1734996T3 - Sposoby i kompozycje do leczenia i profilaktyki choroby związanej z integryną alfa v beta 5 - Google Patents
Sposoby i kompozycje do leczenia i profilaktyki choroby związanej z integryną alfa v beta 5Info
- Publication number
- PL1734996T3 PL1734996T3 PL05763460T PL05763460T PL1734996T3 PL 1734996 T3 PL1734996 T3 PL 1734996T3 PL 05763460 T PL05763460 T PL 05763460T PL 05763460 T PL05763460 T PL 05763460T PL 1734996 T3 PL1734996 T3 PL 1734996T3
- Authority
- PL
- Poland
- Prior art keywords
- integrin
- beta
- alpha
- compositions
- treating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55917504P | 2004-04-02 | 2004-04-02 | |
| EP05763460.2A EP1734996B1 (en) | 2004-04-02 | 2005-03-30 | Methods and compositions for treating and preventing disease associated with alpha v beta 5 integrin |
| PCT/US2005/011222 WO2005094391A2 (en) | 2004-04-02 | 2005-03-30 | METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING DISEASE ASSOCIATED WITH αVβ5 INTEGRIN |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1734996T3 true PL1734996T3 (pl) | 2013-09-30 |
Family
ID=35064346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05763460T PL1734996T3 (pl) | 2004-04-02 | 2005-03-30 | Sposoby i kompozycje do leczenia i profilaktyki choroby związanej z integryną alfa v beta 5 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20050226865A1 (https=) |
| EP (2) | EP2394662B1 (https=) |
| JP (2) | JP5223072B2 (https=) |
| CN (1) | CN1964740A (https=) |
| AU (1) | AU2005229015C1 (https=) |
| CA (1) | CA2562038C (https=) |
| CY (1) | CY1114497T1 (https=) |
| DK (1) | DK1734996T3 (https=) |
| ES (2) | ES2671522T3 (https=) |
| HR (1) | HRP20130782T1 (https=) |
| PL (1) | PL1734996T3 (https=) |
| PT (1) | PT1734996E (https=) |
| RS (1) | RS52918B (https=) |
| WO (1) | WO2005094391A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2767409C (en) * | 2009-07-24 | 2018-10-30 | The Regents Of The University Of California | Methods and compositions for treating and preventing disease associated with .alpha.v.beta.5 integrin |
| WO2013181666A2 (en) * | 2012-06-01 | 2013-12-05 | Isis Pharmaceuticals, Inc. | Antisense compounds targeting genes associated with fibronectin |
| WO2014144616A2 (en) * | 2013-03-15 | 2014-09-18 | Biogen Idec Ma Inc. | Anti-alpha v beta 5 antibodies and uses thereof |
| HK1219740A1 (zh) * | 2013-03-15 | 2017-04-13 | Biogen Ma Inc. | 使用抗αVβ5抗体治疗和预防急性肾损伤 |
| US10005838B2 (en) * | 2013-07-19 | 2018-06-26 | The Regents Of The University Of California | Milk fat globule epidermal growth factor 8 regulates fatty acid uptake |
| MA40536A (fr) * | 2014-09-12 | 2016-03-17 | Biogen Ma Inc | Anticorps anti-alpha v bêta 5 humanisés et leurs utilisations |
| US11339221B2 (en) | 2017-11-01 | 2022-05-24 | Tufts Medical Center, Inc. | Bispecific antibody constructs and methods of use |
Family Cites Families (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US72500A (en) * | 1867-12-24 | Improvement in bleaceisg and scouring hemp, flax, aid other fibres | ||
| US19037A (en) * | 1858-01-05 | Washing-machine | ||
| US19206A (en) * | 1858-01-26 | Hydrant | ||
| US37889A (en) * | 1863-03-10 | Mode of | ||
| US171271A (en) * | 1875-12-21 | Improvement in bob-sleds | ||
| US139398A (en) * | 1873-05-27 | Improvement in lamp-extinguishers | ||
| US181440A (en) * | 1876-08-22 | Improvement in steam-boiler furnaces | ||
| US77321A (en) * | 1868-04-28 | Amos bank | ||
| US10023A (en) * | 1853-09-20 | Machine fob sawing sticks eob broom-handles | ||
| US18192A (en) * | 1857-09-15 | And samuel m | ||
| US19035A (en) * | 1858-01-05 | mallary | ||
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| US5506337A (en) | 1985-03-15 | 1996-04-09 | Antivirals Inc. | Morpholino-subunit combinatorial library and method |
| JPS63501765A (ja) | 1985-11-01 | 1988-07-21 | インタ−ナショナル、ジェネティック、エンジニアリング インコ−ポレ−テッド | 抗体遺伝子のモジュ−ル組立体、それにより産生された抗体及び用途 |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5010175A (en) | 1988-05-02 | 1991-04-23 | The Regents Of The University Of California | General method for producing and selecting peptides with specific properties |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| IE66205B1 (en) | 1990-06-14 | 1995-12-13 | Paul A Bartlett | Polypeptide analogs |
| US5231114A (en) | 1990-06-22 | 1993-07-27 | Wakunaga Seiyaku Kabushiki Kaisha | Polysulfides compounds and lipid peroxidation inhibitor containing the polysulfide compounds as active ingredient |
| US5650489A (en) | 1990-07-02 | 1997-07-22 | The Arizona Board Of Regents | Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof |
| US5527679A (en) | 1991-05-01 | 1996-06-18 | Dana Farber Cancer Institute | β5 protein and DNA encoding the same |
| DE4123341A1 (de) | 1991-07-15 | 1993-01-21 | Thomae Gmbh Dr K | Phenylalkylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE4142366A1 (de) * | 1991-07-15 | 1993-06-24 | Thomae Gmbh Dr K | Phenylalkylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| US5777085A (en) | 1991-12-20 | 1998-07-07 | Protein Design Labs, Inc. | Humanized antibodies reactive with GPIIB/IIIA |
| US6291196B1 (en) * | 1992-01-31 | 2001-09-18 | Research Corporation Technologies, Inc. | Melanoma and prostate cancer specific antibodies for immunodetection and immunotherapy |
| CA2131389A1 (en) | 1992-03-02 | 1993-09-16 | John M. Maraganore | Thrombin receptor antagonists |
| US5573905A (en) | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| US5288514A (en) | 1992-09-14 | 1994-02-22 | The Regents Of The University Of California | Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support |
| US6210671B1 (en) | 1992-12-01 | 2001-04-03 | Protein Design Labs, Inc. | Humanized antibodies reactive with L-selectin |
| US5519134A (en) | 1994-01-11 | 1996-05-21 | Isis Pharmaceuticals, Inc. | Pyrrolidine-containing monomers and oligomers |
| US5593853A (en) | 1994-02-09 | 1997-01-14 | Martek Corporation | Generation and screening of synthetic drug libraries |
| US5539083A (en) | 1994-02-23 | 1996-07-23 | Isis Pharmaceuticals, Inc. | Peptide nucleic acid combinatorial libraries and improved methods of synthesis |
| US5525735A (en) | 1994-06-22 | 1996-06-11 | Affymax Technologies Nv | Methods for synthesizing diverse collections of pyrrolidine compounds |
| US5549974A (en) | 1994-06-23 | 1996-08-27 | Affymax Technologies Nv | Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof |
| US5780426A (en) | 1995-06-07 | 1998-07-14 | Ixsys, Incorporated | Fivemer cyclic peptide inhibitors of diseases involving αv β3 |
| US5569588A (en) | 1995-08-09 | 1996-10-29 | The Regents Of The University Of California | Methods for drug screening |
| HUP9802675A3 (en) * | 1995-08-14 | 2000-09-28 | Scripps Research Inst | Methods and compositions useful for inhibition of alfa-v beta-5 mediated angiogenesis |
| US7053041B1 (en) * | 1996-05-31 | 2006-05-30 | The Scripps Research Institute | Methods and compositions useful for inhibition of αvβ5mediated angiogenesis |
| EP0915698A4 (en) | 1996-05-01 | 1999-08-11 | Lilly Co Eli | TREATMENT PROCEDURE FOR VEGF-RELATED DISEASES |
| NZ513800A (en) | 1996-08-12 | 2001-09-28 | Welfide Corp | Treatment of diseases using Rho kinase inhibitors |
| UA60311C2 (uk) * | 1996-10-02 | 2003-10-15 | Смітклайн Бічам Корпорейшн | Антагоністи рецептора вітронектину, спосіб одержання цих сполук та фармацевтична композиція |
| CO4920232A1 (es) * | 1997-01-08 | 2000-05-29 | Smithkline Beecham Corp | Acidos aceticos dibenzo [a,d] cicloheptano con actividad antagonista del receptor de vitronectin |
| TW589189B (en) | 1997-08-04 | 2004-06-01 | Scras | Kit containing at least one double-stranded RNA combined with at least one anti-viral agent for therapeutic use in the treatment of a viral disease, notably of viral hepatitis |
| EE04752B1 (et) * | 1997-08-08 | 2006-12-15 | The Regents Of The University Of California | Monoklonaalne antikeha, seda tootev hübridoom ja antikeha kasutamine |
| US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
| GB9827152D0 (en) | 1998-07-03 | 1999-02-03 | Devgen Nv | Characterisation of gene function using double stranded rna inhibition |
| DE19842415A1 (de) | 1998-09-16 | 2000-03-23 | Merck Patent Gmbh | Pharmazeutische Zubereitung |
| JP2002531466A (ja) | 1998-12-01 | 2002-09-24 | プロテイン デザイン ラブス, インコーポレイテッド | γ−インターフェロンに対するヒト化抗体 |
| EP1140205A2 (en) | 1998-12-30 | 2001-10-10 | Edema Clearance, Inc. | GENE THERAPY FOR PULMONARY EDEMA USING ADENOVIRUS VECTORS ENCODING Na,K-ATPase |
| EP2314700A1 (en) | 1999-01-28 | 2011-04-27 | Medical College of Georgia Research Institute, Inc | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA |
| DE19956568A1 (de) | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
| US6399581B1 (en) | 1999-05-11 | 2002-06-04 | Harbor Branch Oceanographic Institution, Inc. | Compound possessing potent thrombin receptor antagonist activity |
| CA2352957A1 (en) | 1999-09-29 | 2001-04-05 | Ortho-Mcneil Pharmaceutical, Inc. | Isonipecotamides for the treatment of integrin-mediated disorders |
| CA2386270A1 (en) | 1999-10-15 | 2001-04-26 | University Of Massachusetts | Rna interference pathway genes as tools for targeted genetic interference |
| US6544982B1 (en) | 1999-10-29 | 2003-04-08 | Merck & Co., Inc. | Thrombin receptor antagonists |
| GB9927444D0 (en) | 1999-11-19 | 2000-01-19 | Cancer Res Campaign Tech | Inhibiting gene expression |
| CA2397194C (en) | 2000-01-20 | 2011-05-17 | Mark E. Duggan | Alpha v integrin receptor antagonists |
| EP1254116A4 (en) | 2000-01-24 | 2003-04-23 | Merck & Co Inc | ALPHA V INTEGRIN RECEPTOR ANTAGONISTS |
| US6403612B2 (en) | 2000-01-31 | 2002-06-11 | Merck & Co., Inc. | Thrombin receptor antagonists |
| US6515023B2 (en) | 2000-01-31 | 2003-02-04 | Merck & Co., Inc. | Thrombin receptor antagonists |
| WO2001056607A1 (en) | 2000-02-03 | 2001-08-09 | Eisai Co., Ltd. | Integrin expression inhibitors |
| US6518244B2 (en) | 2000-03-09 | 2003-02-11 | Intimax Corporation | Combinations of heparin cofactor II agonist and platelet IIb/IIIa antagonist, and uses thereof |
| US6970452B2 (en) | 2000-03-13 | 2005-11-29 | Curitell Communications Inc. | Common subscriber managing apparatus and method based on functional modeling of a common subscriber server for use in an ALL-IP network and method therefor |
| AU2001259078A1 (en) | 2000-04-18 | 2001-10-30 | Edema Clearance, Inc. | Gene theraphy for pulmonary edema using adenovirus vectors encoding a beta2adrenergic receptor gene |
| UY26780A1 (es) | 2000-06-15 | 2002-01-31 | Pharmacia Corp | Cicloalquil avb3 antagonistas |
| US7288390B2 (en) * | 2000-08-07 | 2007-10-30 | Centocor, Inc. | Anti-dual integrin antibodies, compositions, methods and uses |
| DE10041423A1 (de) | 2000-08-23 | 2002-03-07 | Merck Patent Gmbh | Biphenylderivate |
| US20020072500A1 (en) | 2000-09-27 | 2002-06-13 | Thomas Rogers | Hydroxy acid integrin antagonists |
| JP2004513953A (ja) | 2000-10-24 | 2004-05-13 | メルク エンド カムパニー インコーポレーテッド | ジベンズオキサゼピンαVインテグリン受容体アンタゴニスト |
| JP2004532616A (ja) | 2000-12-28 | 2004-10-28 | ジョンソン・アンド・ジョンソン・リサーチ・ピー・ティー・ワイ・リミテッド | 二本鎖rna仲介遺伝子抑制 |
| EP1393075A4 (en) | 2001-04-04 | 2006-06-14 | Allergan Inc | METHODS OF SCREENING AND USE OF ANGIOGENESIS INHIBITORS |
| DE60208186T2 (de) | 2001-04-09 | 2006-08-24 | Ortho-Mcneil Pharmaceutical Research Inc. | Chinazolin- und chinazolinähnliche verbindungen zur behandlung von integrin-vermittelten erkrankungen |
| US20040019206A1 (en) | 2001-09-27 | 2004-01-29 | Peter Ruminiski | Lactone integrin antagonists |
| DK1539739T3 (da) * | 2002-08-16 | 2011-03-07 | Janssen Pharmaceutica Nv | Piperidinylforbindelser, der selektivt binder integriner |
| WO2004105757A2 (en) | 2003-05-29 | 2004-12-09 | Schering Aktiengesellschaft | Use of rho-kinase inhibitors in the treatment of aneurysm and cardiac hypertrophy |
| JO3421B1 (ar) | 2011-06-20 | 2019-10-20 | H Lundbeck As | طريقة لإعطاء 1-((1ار.3س)-6-كلورو-3-فينيل-اندان-1-ايل)-1.2.2-ترايميثيل- بيبيرازين واملاجها لمعالجة انفصام الشخصية |
-
2005
- 2005-03-30 ES ES11180077.7T patent/ES2671522T3/es not_active Expired - Lifetime
- 2005-03-30 RS RS20130336A patent/RS52918B/sr unknown
- 2005-03-30 EP EP11180077.7A patent/EP2394662B1/en not_active Expired - Lifetime
- 2005-03-30 EP EP05763460.2A patent/EP1734996B1/en not_active Expired - Lifetime
- 2005-03-30 CA CA2562038A patent/CA2562038C/en not_active Expired - Fee Related
- 2005-03-30 AU AU2005229015A patent/AU2005229015C1/en not_active Ceased
- 2005-03-30 ES ES05763460T patent/ES2411965T3/es not_active Expired - Lifetime
- 2005-03-30 PL PL05763460T patent/PL1734996T3/pl unknown
- 2005-03-30 HR HRP20130782TT patent/HRP20130782T1/hr unknown
- 2005-03-30 JP JP2007506335A patent/JP5223072B2/ja not_active Expired - Fee Related
- 2005-03-30 WO PCT/US2005/011222 patent/WO2005094391A2/en not_active Ceased
- 2005-03-30 CN CNA2005800180446A patent/CN1964740A/zh active Pending
- 2005-03-30 DK DK05763460.2T patent/DK1734996T3/da active
- 2005-03-30 PT PT57634602T patent/PT1734996E/pt unknown
- 2005-03-30 US US11/095,945 patent/US20050226865A1/en not_active Abandoned
-
2009
- 2009-07-17 US US12/505,366 patent/US7815908B2/en not_active Expired - Lifetime
-
2012
- 2012-08-27 JP JP2012186169A patent/JP5681149B2/ja not_active Expired - Fee Related
-
2013
- 2013-08-21 CY CY20131100713T patent/CY1114497T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RS52918B (sr) | 2014-02-28 |
| WO2005094391A3 (en) | 2005-12-01 |
| CY1114497T1 (el) | 2016-10-05 |
| US7815908B2 (en) | 2010-10-19 |
| DK1734996T3 (da) | 2013-06-10 |
| EP1734996A2 (en) | 2006-12-27 |
| CN1964740A (zh) | 2007-05-16 |
| JP2013028611A (ja) | 2013-02-07 |
| AU2005229015B2 (en) | 2012-08-30 |
| JP5223072B2 (ja) | 2013-06-26 |
| WO2005094391A2 (en) | 2005-10-13 |
| HK1098077A1 (en) | 2007-07-13 |
| EP1734996B1 (en) | 2013-05-22 |
| EP2394662A3 (en) | 2012-02-22 |
| EP1734996A4 (en) | 2008-09-10 |
| US20090280118A1 (en) | 2009-11-12 |
| EP2394662A2 (en) | 2011-12-14 |
| HRP20130782T1 (en) | 2013-09-30 |
| AU2005229015C1 (en) | 2013-01-17 |
| CA2562038C (en) | 2017-04-25 |
| US20050226865A1 (en) | 2005-10-13 |
| JP2007531733A (ja) | 2007-11-08 |
| AU2005229015A1 (en) | 2005-10-13 |
| CA2562038A1 (en) | 2005-10-13 |
| JP5681149B2 (ja) | 2015-03-04 |
| ES2671522T3 (es) | 2018-06-06 |
| PT1734996E (pt) | 2013-07-18 |
| ES2411965T3 (es) | 2013-07-09 |
| EP2394662B1 (en) | 2018-03-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL1771201T3 (pl) | Kompozycje i sposoby leczenia lub profilaktyki choroby związanej ze szczawianem | |
| CA2645871A1 (en) | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OXALATE-ASSOCIATED DISEASE | |
| SI1920065T1 (sl) | Protitelesa anti-alfavbeta6 in njihova uporaba | |
| IL178390A0 (en) | Methods and compositions for the treatment, prevention or management of dysfunctional sleep and dysfunctional sleep associated with disease | |
| TWI348891B (en) | Composition for preventing plant diseases and method for preventing the diseases | |
| TWI372752B (en) | Pyrazinecarboxamide derivatives and plant disease controlling agents containing the same | |
| EP1737482A4 (en) | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES | |
| EP1944277A4 (en) | ANTI-ARTICLE AND ANTIBACITY COMPOSITION | |
| EP1589996A4 (en) | ANTI-INTEGRIN ALPHA BETA 3 ANTIBODY FORMULATIONS AND ITS USES | |
| EP1668024A4 (en) | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES INCLUDING INFLAMMATORY SUFFERING | |
| IL187620A0 (en) | 17??-hsd1 and sts inhibitors | |
| EP1545578A4 (en) | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASES | |
| EP1512415A4 (en) | LURE COMPOSITION FOR TREATING AND PREVENTING INFLAMMATORY DISEASES | |
| SI1921077T1 (sl) | Sredstvo za zdravljenje in/ali preprečevanje motnje spanja | |
| ZA200805419B (en) | Compositions and methods for preventing or treating inflammatory bowel disease | |
| ZA200707407B (en) | Composition for preventing plant diseases and method for preventing the diseases | |
| AU2003212850A8 (en) | Methods and compositions for treating cardiovascular disease | |
| PL1908779T3 (pl) | Pochodne tymozyny beta 4 i ich zastosowanie | |
| EP1583966A4 (en) | METHODS AND COMPOSITIONS FOR TREATING CARDIOVASCULAR DISEASES USING GENES 1722, 10280, 59917, 85553, 10653, 9235, 21668, 17794, 2210, 6169, 10102, 21061, 17662, 1468, 12282, 6350, 9035, 1820, 23652, 7301, 8925, 8701, 3533, 9462, 9123, 12788, 17729, 65552, 1261, 21476, 33770, 9380, 2569654, 33 | |
| HRP20130782T1 (en) | Methods and compositions for treating and preventing disease associated with alpha v beta 5 integrin | |
| SI1734996T1 (sl) | Postopki in sestavki za zdravljenje in preprečevanje bolezni, povezane z integrinom alfa v beta 5 | |
| ZA200804816B (en) | Pyrazinecarboxamide derivatives and plant disease controlling agents containing the same | |
| EP1807067A4 (en) | SPHINGOSINKINASE ACTIVATOR AND TREATMENT AGENT FOR SKIN DISEASES THEREWITH | |
| GB0403696D0 (en) | Process and composition | |
| EP1660114A4 (en) | METHOD AND COMPOSITIONS FOR TREATING DYSFUNCTIONS OF THE EXTRACELLULAR MATRIX |