CN1964740A - 治疗和预防与αVβ5整联蛋白有关的疾病的方法和组合物 - Google Patents

治疗和预防与αVβ5整联蛋白有关的疾病的方法和组合物 Download PDF

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Publication number
CN1964740A
CN1964740A CNA2005800180446A CN200580018044A CN1964740A CN 1964740 A CN1964740 A CN 1964740A CN A2005800180446 A CNA2005800180446 A CN A2005800180446A CN 200580018044 A CN200580018044 A CN 200580018044A CN 1964740 A CN1964740 A CN 1964740A
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CN
China
Prior art keywords
antibody
alkyl
αvβ5
aryl
alula
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800180446A
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English (en)
Chinese (zh)
Inventor
迪安·谢泼德
阿马·阿塔基利特
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University of California San Diego UCSD
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University of California San Diego UCSD
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Publication of CN1964740A publication Critical patent/CN1964740A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CNA2005800180446A 2004-04-02 2005-03-30 治疗和预防与αVβ5整联蛋白有关的疾病的方法和组合物 Pending CN1964740A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55917504P 2004-04-02 2004-04-02
US60/559,175 2004-04-02

Publications (1)

Publication Number Publication Date
CN1964740A true CN1964740A (zh) 2007-05-16

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ID=35064346

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CNA2005800180446A Pending CN1964740A (zh) 2004-04-02 2005-03-30 治疗和预防与αVβ5整联蛋白有关的疾病的方法和组合物

Country Status (14)

Country Link
US (2) US20050226865A1 (https=)
EP (2) EP2394662B1 (https=)
JP (2) JP5223072B2 (https=)
CN (1) CN1964740A (https=)
AU (1) AU2005229015C1 (https=)
CA (1) CA2562038C (https=)
CY (1) CY1114497T1 (https=)
DK (1) DK1734996T3 (https=)
ES (2) ES2671522T3 (https=)
HR (1) HRP20130782T1 (https=)
PL (1) PL1734996T3 (https=)
PT (1) PT1734996E (https=)
RS (1) RS52918B (https=)
WO (1) WO2005094391A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102481347A (zh) * 2009-07-24 2012-05-30 加州大学董事会 治疗和预防整合素αvβ5相关疾病的方法及组合物
CN105392801A (zh) * 2013-03-15 2016-03-09 比奥根Ma公司 使用抗αvβ5抗体治疗和预防急性肾损伤
CN107001469A (zh) * 2014-09-12 2017-08-01 比奥根Ma公司 人源化抗‑αvβ5抗体及其用途

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US10005838B2 (en) * 2013-07-19 2018-06-26 The Regents Of The University Of California Milk fat globule epidermal growth factor 8 regulates fatty acid uptake
US11339221B2 (en) 2017-11-01 2022-05-24 Tufts Medical Center, Inc. Bispecific antibody constructs and methods of use

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102481347A (zh) * 2009-07-24 2012-05-30 加州大学董事会 治疗和预防整合素αvβ5相关疾病的方法及组合物
CN105392801A (zh) * 2013-03-15 2016-03-09 比奥根Ma公司 使用抗αvβ5抗体治疗和预防急性肾损伤
CN107001469A (zh) * 2014-09-12 2017-08-01 比奥根Ma公司 人源化抗‑αvβ5抗体及其用途

Also Published As

Publication number Publication date
RS52918B (sr) 2014-02-28
WO2005094391A3 (en) 2005-12-01
CY1114497T1 (el) 2016-10-05
US7815908B2 (en) 2010-10-19
DK1734996T3 (da) 2013-06-10
EP1734996A2 (en) 2006-12-27
JP2013028611A (ja) 2013-02-07
AU2005229015B2 (en) 2012-08-30
JP5223072B2 (ja) 2013-06-26
WO2005094391A2 (en) 2005-10-13
HK1098077A1 (en) 2007-07-13
EP1734996B1 (en) 2013-05-22
EP2394662A3 (en) 2012-02-22
EP1734996A4 (en) 2008-09-10
US20090280118A1 (en) 2009-11-12
EP2394662A2 (en) 2011-12-14
HRP20130782T1 (en) 2013-09-30
AU2005229015C1 (en) 2013-01-17
CA2562038C (en) 2017-04-25
US20050226865A1 (en) 2005-10-13
JP2007531733A (ja) 2007-11-08
AU2005229015A1 (en) 2005-10-13
CA2562038A1 (en) 2005-10-13
JP5681149B2 (ja) 2015-03-04
ES2671522T3 (es) 2018-06-06
PT1734996E (pt) 2013-07-18
ES2411965T3 (es) 2013-07-09
EP2394662B1 (en) 2018-03-21
PL1734996T3 (pl) 2013-09-30

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