PL1908779T3 - Pochodne tymozyny beta 4 i ich zastosowanie - Google Patents

Pochodne tymozyny beta 4 i ich zastosowanie

Info

Publication number
PL1908779T3
PL1908779T3 PL06761426T PL06761426T PL1908779T3 PL 1908779 T3 PL1908779 T3 PL 1908779T3 PL 06761426 T PL06761426 T PL 06761426T PL 06761426 T PL06761426 T PL 06761426T PL 1908779 T3 PL1908779 T3 PL 1908779T3
Authority
PL
Poland
Prior art keywords
derivatives
thymosin beta
thymosin
beta
Prior art date
Application number
PL06761426T
Other languages
English (en)
Inventor
Liya Nie
Suyong Ma
S Xu
Meiyu Wen
Original Assignee
Beijing Northland Biotech Co
Biotoxtech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN 200510083894 external-priority patent/CN1896096A/zh
Priority claimed from CNB2005101032937A external-priority patent/CN100484957C/zh
Application filed by Beijing Northland Biotech Co, Biotoxtech Co Ltd filed Critical Beijing Northland Biotech Co
Publication of PL1908779T3 publication Critical patent/PL1908779T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57581—Thymosin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PL06761426T 2005-07-15 2006-07-14 Pochodne tymozyny beta 4 i ich zastosowanie PL1908779T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN 200510083894 CN1896096A (zh) 2005-07-15 2005-07-15 基因工程方法生产的高活性胸腺素β4衍生物
CNB2005101032937A CN100484957C (zh) 2005-09-23 2005-09-23 胸腺素β4衍生物及其应用
EP06761426A EP1908779B1 (en) 2005-07-15 2006-07-14 Thymosin beta 4 derivatives and use thereof
PCT/CN2006/001679 WO2007009359A1 (fr) 2005-07-15 2006-07-14 Derives de thymosine beta 4 et utilisation

Publications (1)

Publication Number Publication Date
PL1908779T3 true PL1908779T3 (pl) 2013-06-28

Family

ID=37668439

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06761426T PL1908779T3 (pl) 2005-07-15 2006-07-14 Pochodne tymozyny beta 4 i ich zastosowanie

Country Status (7)

Country Link
US (1) US7816321B2 (pl)
EP (1) EP1908779B1 (pl)
JP (1) JP5180074B2 (pl)
KR (1) KR100984635B1 (pl)
CN (1) CN100582121C (pl)
PL (1) PL1908779T3 (pl)
WO (1) WO2007009359A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2008001084A (es) * 2005-07-26 2008-03-11 Regenerx Biopharmaceuticals Composiciones para el tratamiento o prevencion del deterioro, lesion o dano de tejido debido a insuficiencia cardiaca congestiva.
GB2476789A (en) 2009-11-10 2011-07-13 Gl Holdings Inc Bv Use of thymosin for treatment of type 2 diabetes
US9504730B2 (en) 2010-09-30 2016-11-29 Regenerx Biopharmaceuticals, Inc. Method of achieving a thymosin beta 4 concentration in a human patient
WO2012126047A1 (en) * 2011-03-18 2012-09-27 Adistem Ltd Agent and method for treating pain and reducing inflammation
CN103724422B (zh) * 2014-01-13 2015-10-21 哈尔滨吉象隆生物技术有限公司 一种裂解胸腺素β4的方法
CN104311672B (zh) * 2014-10-21 2017-07-11 中国药科大学 一种具有肿瘤细胞靶向性的抑制剂多肽
CN106692949B (zh) * 2016-12-23 2022-03-15 北京诺思兰德生物技术股份有限公司 一种用于治疗眼部疾病的药物及其组合物
KR101910908B1 (ko) * 2017-06-14 2018-10-24 (주)휴온스 Gly-Tβ4 (Gly-티모신β4)을 함유하는 안구건조증 치료용 약학적 조성물
KR101946789B1 (ko) * 2018-01-26 2019-02-12 (주)휴온스 이황화결합 이성질화효소 신호 펩타이드를 포함하는 재조합 벡터 및 이의 용도
KR102140531B1 (ko) * 2018-08-07 2020-08-04 (주)휴온스 Gly-Tβ4의 제조방법
CN108853483B (zh) * 2018-08-10 2022-03-15 北京诺思兰德生物技术股份有限公司 经修饰的胸腺素β4在治疗脑缺血再灌注损伤方面的用途
CN110215513B (zh) * 2018-11-15 2022-02-22 北京诺思兰德生物技术股份有限公司 经修饰的胸腺素β4在治疗放射性肠炎方面的用途
CN109865127B (zh) * 2018-11-22 2022-03-04 北京诺思兰德生物技术股份有限公司 经修饰的胸腺素β4在治疗糖尿病周围神经病变方面的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4297276A (en) * 1979-03-23 1981-10-27 Hoffman-La Roche Inc. Thymosin beta 3 and beta 4
US4395404A (en) * 1982-05-14 1983-07-26 George Washington University Synthetic thymosin β3 and β4 analogues
EP1100529B2 (en) * 1998-07-30 2010-08-25 The Government of the United States of America, as repres. by the Secretary of Health and Human Services, Nat. Inst. of Health Thymosin beta 4 promotes wound repair
US7585943B2 (en) * 2005-04-20 2009-09-08 Viromed Co., Ltd. Compositions and methods for fusion protein separation

Also Published As

Publication number Publication date
EP1908779A1 (en) 2008-04-09
JP2009500045A (ja) 2009-01-08
KR20080040708A (ko) 2008-05-08
WO2007009359A1 (fr) 2007-01-25
EP1908779A4 (en) 2009-09-30
JP5180074B2 (ja) 2013-04-10
US20090298758A1 (en) 2009-12-03
KR100984635B1 (ko) 2010-10-01
CN101218249A (zh) 2008-07-09
EP1908779B1 (en) 2013-01-09
CN100582121C (zh) 2010-01-20
US7816321B2 (en) 2010-10-19

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