SI1771201T1 - Sestavki in metode za zdravljenje ali preprečevanje z oksalatom-povezanih bolezni - Google Patents

Sestavki in metode za zdravljenje ali preprečevanje z oksalatom-povezanih bolezni

Info

Publication number
SI1771201T1
SI1771201T1 SI200531905T SI200531905T SI1771201T1 SI 1771201 T1 SI1771201 T1 SI 1771201T1 SI 200531905 T SI200531905 T SI 200531905T SI 200531905 T SI200531905 T SI 200531905T SI 1771201 T1 SI1771201 T1 SI 1771201T1
Authority
SI
Slovenia
Prior art keywords
compositions
treating
methods
related disease
preventing oxalate
Prior art date
Application number
SI200531905T
Other languages
English (en)
Inventor
Harmeet Sidhu
Original Assignee
Oxthera Intellectual Property Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35510266&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1771201(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Oxthera Intellectual Property Ab filed Critical Oxthera Intellectual Property Ab
Publication of SI1771201T1 publication Critical patent/SI1771201T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • A61K38/443Oxidoreductases (1) acting on CH-OH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51Lyases (4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/54Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/04Drugs for disorders of the urinary system for urolithiasis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/03Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with oxygen as acceptor (1.2.3)
    • C12Y102/03004Oxalate oxidase (1.2.3.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y208/00Transferases transferring sulfur-containing groups (2.8)
    • C12Y208/03CoA-transferases (2.8.3)
    • C12Y208/03016Formyl-CoA transferase (2.8.3.16)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/01Carboxy-lyases (4.1.1)
    • C12Y401/01002Oxalate decarboxylase (4.1.1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/01Carboxy-lyases (4.1.1)
    • C12Y401/01008Oxalyl-CoA decarboxylase (4.1.1.8)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
SI200531905T 2004-06-15 2005-06-15 Sestavki in metode za zdravljenje ali preprečevanje z oksalatom-povezanih bolezni SI1771201T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/868,242 US8486389B2 (en) 1997-05-23 2004-06-15 Compositions and methods for treating or preventing oxalate-related disease
EP05786347.4A EP1771201B1 (en) 2004-06-15 2005-06-15 Compositions and methods for treating or preventing oxalate-related disease
PCT/US2005/021134 WO2005123116A2 (en) 2004-06-15 2005-06-15 Compositions and methods for treating or preventing oxalate-related disease

Publications (1)

Publication Number Publication Date
SI1771201T1 true SI1771201T1 (sl) 2014-12-31

Family

ID=35510266

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200532230T SI2803366T1 (sl) 2004-06-15 2005-06-15 Sestavki za zdravljenje ali preprečevanje z oksalatom-povezane bolezni
SI200531905T SI1771201T1 (sl) 2004-06-15 2005-06-15 Sestavki in metode za zdravljenje ali preprečevanje z oksalatom-povezanih bolezni

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI200532230T SI2803366T1 (sl) 2004-06-15 2005-06-15 Sestavki za zdravljenje ali preprečevanje z oksalatom-povezane bolezni

Country Status (13)

Country Link
US (3) US8486389B2 (sl)
EP (2) EP1771201B1 (sl)
CN (2) CN104998253A (sl)
CY (2) CY1115745T1 (sl)
DK (2) DK1771201T3 (sl)
ES (2) ES2692148T3 (sl)
HK (2) HK1198922A1 (sl)
LT (1) LT2803366T (sl)
PL (2) PL1771201T3 (sl)
PT (2) PT1771201E (sl)
SI (2) SI2803366T1 (sl)
TR (1) TR201815200T4 (sl)
WO (1) WO2005123116A2 (sl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8486389B2 (en) 1997-05-23 2013-07-16 Oxthera, Inc. Compositions and methods for treating or preventing oxalate-related disease
JP2005537037A (ja) * 2001-10-05 2005-12-08 イクシオン・バイオテクノロジー・インコーポレーテッド 流体の蓚酸塩濃度を減少させる物質および方法
US7785635B1 (en) * 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US20050158294A1 (en) 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
WO2005110469A2 (en) * 2004-05-07 2005-11-24 Oxthera, Inc. Methods and compositions for reducing oxalate concentrations
DK1880001T3 (da) 2005-05-31 2011-09-12 Iams Company Feline probiotiske lactobacilli
CA2607949C (en) 2005-05-31 2012-09-25 Thomas William-Maxwell Boileau Feline probiotic bifidobacteria
CA2610159C (en) 2005-06-10 2015-03-31 Altus Pharmaceuticals Inc. Methods to reduce oxalate concentration by administration of oxalate oxidase crystals
AU2005339139A1 (en) * 2005-12-14 2007-06-21 Oxthera, Inc. Pharmaceutical compositions and methods for treating or preventing oxalate-related disease
DE602006020347D1 (de) * 2005-12-16 2011-04-07 Oxthera Inc Zusammensetzungen und verfahren zur oxalatreduktion
EP2046373B1 (en) * 2006-08-02 2013-03-20 Althea Technologies, Inc. Crystallized oxalate decarboxylase and methods of use
AU2008211600B8 (en) 2007-02-01 2014-02-13 Mars, Incorporated Method for decreasing inflammation and stress in a mammal using glucose antimetabolites, avocado or avocado extracts
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
FR2936952A1 (fr) * 2008-10-09 2010-04-16 Monique Bellec Administration par voie orale de medicaments et complements nutritionnels
CN101554237B (zh) * 2009-03-16 2013-11-06 武汉康复得生物科技有限公司 植物纤维或微生物不溶组分中的草酸降解酶的制备方法
US8431122B2 (en) 2009-07-02 2013-04-30 Oxthera Intellectual Property Ab Purification and isolation of recombinant oxalate degrading enzymes and spray-dried particles containing oxalate degrading enzymes
ES2673269T3 (es) 2009-07-02 2018-06-21 Oxthera Intellectual Property Ab Purificación y aislamiento de enzimas de degradación de oxalato recombinantes
DK2449098T3 (en) * 2009-07-02 2017-03-06 Oxthera Intellectual Property Ab PURIFICATION AND INSULATION OF RECOMBINANT OXALATE DEGRADING ENZYMES AND SPRAY DRIED PARTICLES CONTAINING OXALATE DEGRADING ENZYMER
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
EP2504428A4 (en) * 2009-11-25 2013-09-25 Captozyme Llc METHOD AND COMPOSITIONS FOR TREATING OXALATE-MEDIATED SUFFERING
WO2014113648A1 (en) 2013-01-18 2014-07-24 Allena Pharmaceuticals, Inc. Crystallized oxalate decarboxylase and methods of use
JP6574414B2 (ja) 2013-06-07 2019-09-11 アレナ ファーマシューティカルズ, インコーポレイテッド 透析のための組成物、方法、および器具
WO2015002588A1 (en) * 2013-07-05 2015-01-08 Oxthera Intellectual Property Ab Secretagogues derived from oxalobacter formigenes
WO2016161455A2 (en) 2015-04-02 2016-10-06 Captozyme, Llc High efficiency oxalate-degrading enzymes for degradation of insoluble and soluble oxalate
TN2018000420A1 (en) * 2016-06-13 2020-06-15 Oxthera Intellectual Property Ab Compositions and methods for the treatment or prevention of oxalate-related disorders
AU2017376780A1 (en) 2016-12-15 2019-07-04 Novome Biotechnologies, Inc. Compositions and methods for modulating growth of a genetically modified gut bacterial cell
WO2020018799A1 (en) 2018-07-18 2020-01-23 The University Of Chicago Compositions comprising sel1-derived peptides and methods of treatment/prevention of excess oxalate levels and associated conditions/diseases therewith

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4205132A (en) * 1978-07-17 1980-05-27 Microlife Technics, Inc. Lyophilization of bacteria
DE3030185A1 (de) 1980-08-07 1982-04-08 Kohlbecker, Günther, 3000 Hannover Verfahren zur enzymatischen entfernung von oxalat mittels oxalat-oxidase
DE3204284A1 (de) 1982-02-06 1983-08-18 Kohlbecker, Günther, 3000 Hannover Verfahren zur enzymatischen entfernung von sauerstoff
JPS5968344A (ja) 1982-10-12 1984-04-18 Agency Of Ind Science & Technol 非対称機能膜及びその製法
US4888182A (en) 1983-04-11 1989-12-19 Board Of Regents Of The University Of Texas System Compositions and methods of treating calcium renal stones
US4539118A (en) 1984-03-23 1985-09-03 Sigma Chemical Company Rapid, accurate method of separation of oxalate from urine and other biological fluids
US5263992A (en) * 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
US5427935A (en) * 1987-07-24 1995-06-27 The Regents Of The University Of Michigan Hybrid membrane bead and process for encapsulating materials in semi-permeable hybrid membranes
US5279827A (en) 1991-01-16 1994-01-18 Allegheny-Singer Research Institute Extract and pharmaceutical composition for treatment of calcium oxalate stone disease and viral infections
US5206219A (en) * 1991-11-25 1993-04-27 Applied Analytical Industries, Inc. Oral compositions of proteinaceous medicaments
US5286495A (en) * 1992-05-11 1994-02-15 University Of Florida Process for microencapsulating cells
HU219140B (hu) * 1992-11-30 2001-02-28 Zeneca Ltd. Oxalát-dekarboxilázt kódoló izolált DNS fragmens, az azt tartalmazó rekombináns molekula, és a rekombináns molekulát tartalmazó transzformált növényi sejtek
AU6701694A (en) * 1993-04-16 1994-11-08 Mccormick & Company, Inc. Encapsulation compositions
US5554147A (en) * 1994-02-01 1996-09-10 Caphco, Inc. Compositions and devices for controlled release of active ingredients
US5788687A (en) * 1994-02-01 1998-08-04 Caphco, Inc Compositions and devices for controlled release of active ingredients
US5505713A (en) 1994-04-01 1996-04-09 Minimed Inc. Indwelling catheter with stable enzyme coating
JPH10500019A (ja) 1994-05-18 1998-01-06 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド ヒトのオキサリル−CoAデカルボキシラーゼ
US6090628A (en) * 1994-06-20 2000-07-18 University Of Florida Materials and methods for detection of Oxalobactor formigenes
US5912125A (en) 1994-06-20 1999-06-15 University Of Florida Materials and methods for detection of oxalobacter
US6214980B1 (en) * 1994-06-20 2001-04-10 University Of Florida Materials and methods for detection of Oxalobacte formigenes
US5604111A (en) 1994-06-20 1997-02-18 University Of Florida Research Foundation Method and kit for detection of oxalate
US6033719A (en) * 1996-04-25 2000-03-07 Medtronic, Inc. Method for covalent attachment of biomolecules to surfaces of medical devices
SE9603029D0 (sv) 1996-08-20 1996-08-20 Svenska Traeforskningsinst Method for lowering the level of oxalic acid
US6297425B1 (en) 1997-03-21 2001-10-02 Pioneer Hi-Bred International, Inc. Gene encoding oxalate decarboxylase from aspergillus phoenices
US6355242B1 (en) * 1997-05-23 2002-03-12 Ixion Biotechnology, Inc. Materials and methods for treating or preventing oxalate-related disease
DE69841200D1 (de) 1997-05-23 2009-11-12 Oxthera Inc Oxalate-abbauende mikroorganismen oder oxalate-abbauende enzyme zur verhütung der oxalate-verwandten krankheiten
US8486389B2 (en) 1997-05-23 2013-07-16 Oxthera, Inc. Compositions and methods for treating or preventing oxalate-related disease
US20040120941A1 (en) 1997-05-23 2004-06-24 Allison Milton J. Materials and methods for treating or preventing oxalate-related disease
US6080404A (en) * 1997-09-05 2000-06-27 University Of Florida Materials and methods for removal of substances from fluids
US6566407B2 (en) * 1997-11-05 2003-05-20 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US5985938A (en) * 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6203797B1 (en) 1998-01-06 2001-03-20 Stephen C. Perry Dietary supplement and method for use as a probiotic, for alleviating the symptons associated with irritable bowel syndrome
US6153252A (en) * 1998-06-30 2000-11-28 Ethicon, Inc. Process for coating stents
JP5408684B2 (ja) 1998-10-09 2014-02-05 ゼネラル ミルズ インコーポレイテッド 非連続な保存安定粒子を得るためにマトリックスに感受性液体成分を封入する方法
IT1309427B1 (it) * 1999-05-28 2002-01-23 Mendes S U R L Composizione dietetica o farmaceutica utile per la prevenzione o iltrattamento dell'iperossaluria e suo uso
CZ20014319A3 (cs) 1999-06-07 2002-04-17 Nanosphere, Inc. Způsob potahování jádrového materiálu a potahované částice
DE10026541A1 (de) 2000-05-27 2001-11-29 Zeiss Carl Vorrichtung zur präzisen Positionierung eines Bauteils, insbesondere eines optischen Bauteiles
JP2005537037A (ja) 2001-10-05 2005-12-08 イクシオン・バイオテクノロジー・インコーポレーテッド 流体の蓚酸塩濃度を減少させる物質および方法
US7407668B2 (en) * 2002-01-24 2008-08-05 Boston Scimed, Inc. Medical articles having enzymatic surfaces for localized therapy
US6929940B1 (en) * 2002-08-20 2005-08-16 University Of Florida Research Foundation, Inc. Polynucleotides encoding oxalate decarboxylase from Aspergillus niger and methods of use
WO2004018634A2 (en) 2002-08-20 2004-03-04 University Of Florida Polynucleotide encoding oxalate decarboxylase from aspergillus niger and methods of use
WO2005110469A2 (en) 2004-05-07 2005-11-24 Oxthera, Inc. Methods and compositions for reducing oxalate concentrations
AU2005339139A1 (en) 2005-12-14 2007-06-21 Oxthera, Inc. Pharmaceutical compositions and methods for treating or preventing oxalate-related disease
DE602006020347D1 (de) 2005-12-16 2011-04-07 Oxthera Inc Zusammensetzungen und verfahren zur oxalatreduktion
EP2046373B1 (en) 2006-08-02 2013-03-20 Althea Technologies, Inc. Crystallized oxalate decarboxylase and methods of use
US8431122B2 (en) 2009-07-02 2013-04-30 Oxthera Intellectual Property Ab Purification and isolation of recombinant oxalate degrading enzymes and spray-dried particles containing oxalate degrading enzymes

Also Published As

Publication number Publication date
CN101166421A (zh) 2008-04-23
PL2803366T3 (pl) 2018-12-31
US10653726B2 (en) 2020-05-19
CY1120782T1 (el) 2019-12-11
US20190091268A1 (en) 2019-03-28
ES2692148T3 (es) 2018-11-30
EP2803366A3 (en) 2015-02-18
PT2803366T (pt) 2018-11-06
HK1198922A1 (en) 2015-06-19
US20140030324A1 (en) 2014-01-30
DK2803366T3 (en) 2018-11-05
PL1771201T3 (pl) 2015-01-30
TR201815200T4 (tr) 2018-11-21
WO2005123116A3 (en) 2008-01-03
EP1771201A2 (en) 2007-04-11
ES2522898T3 (es) 2014-11-19
EP2803366A2 (en) 2014-11-19
US10149866B2 (en) 2018-12-11
CY1115745T1 (el) 2017-01-25
WO2005123116A2 (en) 2005-12-29
EP1771201A4 (en) 2011-01-19
HK1216080A1 (zh) 2016-10-14
US8486389B2 (en) 2013-07-16
DK1771201T3 (da) 2014-11-03
PT1771201E (pt) 2014-11-06
CN104998253A (zh) 2015-10-28
LT2803366T (lt) 2018-12-27
EP1771201B1 (en) 2014-08-13
EP2803366B1 (en) 2018-08-01
SI2803366T1 (sl) 2018-12-31
US20040234514A1 (en) 2004-11-25

Similar Documents

Publication Publication Date Title
HK1216080A1 (zh) 用於治療或預防草酸鹽相關疾病的組合物和方法
CA2645871A1 (en) PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OXALATE-ASSOCIATED DISEASE
EP1737482A4 (en) COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES
GB2423928B (en) Methods and compositions for treating pain
PT1755391E (pt) Métodos e composições para o tratamento de neuropatias
HK1121952A1 (en) Methods and compositions for treating conditions
IL184047A0 (en) Methods and compositions for treating amyloid-related diseases
EP1959929A4 (en) COMPOSITIONS AND METHODS FOR TREATING DERMATOLOGICAL SUFFERING
EP1827407A4 (en) METHODS, ASSAYS AND COMPOSITIONS FOR THE TREATMENT OF RETINOL CONDITIONAL DISEASES
IL186963A0 (en) Methods and compositions for treating pain
EP1890712A4 (en) COMPOSITIONS AND METHODS FOR TREATING PAIN
EP1755537A4 (en) METHOD AND COMPOSITIONS FOR PREVENTING OR TREATING PERIODONTOPATHIA
ZA200708575B (en) Methods and compositions for treating or preventing cancer
IL176919A0 (en) Methods and compositions for treating cancer
ZA200705297B (en) Methods and compositions for treating amyloid related diseases
EP2069391A4 (en) COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING EYE DRYING
ZA200805419B (en) Compositions and methods for preventing or treating inflammatory bowel disease
HK1129596A1 (en) Methods and compositions for treating disease
EP1959982A4 (en) METHODS AND COMPOSITIONS FOR PREVENTING AND / OR TREATING PANCREATITIS
EP1796712A4 (en) METHOD AND COMPOSITIONS FOR TREATING HYPERCHOLESTEROLEMIA
PT1965816T (pt) Composições farmacêuticas e métodos de tratamento ou prevenção de uma doença associada a oxalato
GB0522732D0 (en) Composition and method for treating disease
GB0507963D0 (en) Composition and method for treating disease
AU2004901220A0 (en) Compositions and methods for treatment disease
AU2004900555A0 (en) Method and compositions for treating vascular disease