PL128583B1 - Method of obtaining new derivatives of 1-phenyl ethanol - Google Patents
Method of obtaining new derivatives of 1-phenyl ethanol Download PDFInfo
- Publication number
- PL128583B1 PL128583B1 PL1981235908A PL23590881A PL128583B1 PL 128583 B1 PL128583 B1 PL 128583B1 PL 1981235908 A PL1981235908 A PL 1981235908A PL 23590881 A PL23590881 A PL 23590881A PL 128583 B1 PL128583 B1 PL 128583B1
- Authority
- PL
- Poland
- Prior art keywords
- formula
- obtaining new
- new derivatives
- phenyl ethanol
- chj
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Description
***128 583 CH,-0-CY~A-Ó-0^__ OH '3 ( yCH-CHj-NH-OCH,), CH3-0-C^C-0- O O Wzór 47 o 9 CH3CH2-0-C-^yC-0^_^ OH (yCH-CH2-NH-C(CH3k.CHjCHj-O-C-/ VC-0—W A N=/ q Wzór 48 0 rs ° CH3CH2CH2-0-C- CHaCHjCHj-O-C-O-C-O-^^ W2br49 0 0 CH3 0 0 HC-O-C^-C-O. OH CH3 fVCH -CHj- NH -CICH^. 3 CH3 =^ HC-0-C-fVc-0 i i \—/ I Wzór 50 CH3 O O H0-^ OH ( yCH-CHj-NH-CfCHj), O 0 O Wzór 51 -TS-* ~^^ ffl.-C-0-t^C-o "K0H CHaCa-C-O-f-yC-O^^0""^^-0'^ Jl V / ii o — o U HO Wzór 52 CH.^CHfC-o-Of-O-^™"0'2""""^ Ó Ó Wzór 53 H0-. oh A W/ i Wzór 54 0 O HO 9H3 r\m CH3-C- C-0/\c 03=/CH-CH2-NH-C(CH3,; dH3 6 w* ^r55128 583 HO CHs-CH-C^-C-O-^yc^o-LA^-CH^NH-a^^ CH3 o Ó H0 OH Wzór56 VcCHlc-„^C-oJ^H-C^_c(CH3,3 CH3 ó ° HO . «»S7 HO- r/-\ c_ 0jL/^H-CK^NH- C(CH3L 0 un Wzór 58 CH3'°-C/C- O-W ^^2" NH-CfCH^ H0. OH asc^o-c^Tc-oJ^™^-""-^1 q ^=^ q Wzór 60 33 L ^*L OH CHaCH^-o-cOc-O-^™-^1*1-^^ Ó ^"'^ O Wzór 61 CH3 /^-\ i HC- O-C-^c-0J=/ CH-CH-NH-«CH3: CH3 O O Wzór 62 ho-O-c-o-3^ scnr O \A£ór 63 f~YC-0~__^ OH CH, * VCH-CH2-NH-CH CH2 1 ^ s L 3 Wzór64 ^H2 £c-°- HO O (jKH-CHj-NH-Ol NCH2 O128 583 HO.OH S—. (' \\ ru /*it . •• * [2 ^ó CH2" o o Wzór66 CH3-C-0-^C-0 9" CH2 ch3-C-o-Qc-o-^CH-ch^nh-c< , 0 0 Wzór 67 CHj CH3 0 O CH3-C - c-O^C-0 CH3 W V\ ?H M ch3 w £ ^r68 CHa CH3 0 GH3- C - C-0 __ 0 CH3 ^\c-0-~^ OH ^CH2 CH-CHj-NH-CH ^CH2 ch3 /-\,0-^ NcHr - c-o<ó /W CH3-C - C-0-2 0 Wzór 69 CH3 0 W ( VCH-CHrNH-CH CH2 HO-C-^C-0-^7 V 6 b Wzór 70 CK 9 _ o i3-o-c-Qc-o OH .CH, CH3- O-C-O-c-oJLW-<*-M- owó cw2 ru Wzór71 CH3-C-0-/C-0~W CH~^-NH-< 2,128 583 CHjC^-C-O 6 HO. OH /-^ fyCH-CH,-NH-CH ¦{ C-0 —^^ 6 S-\ CH, Wzór 74 CHj HO. OH CH, /~\i.. - ../"¦¦*v ^3 ^ CH-CH2-NH-CH: CH, CHi-c- c-o/yc-o--^ . «"" CH3 O O HQ ^ CH3-CH-CH2-C-0-fVc-0—-^=^ NrH,x * 4 i.. z ' \=/ J! ... Wzór76 tM2 OH ./C\ CH, O .0 CH, CH3- C•- C-O-W CH3 ó ° H°^ OH CHj {^yCH-C^-NH-CH^ fe Wzór77 ^ /^-C_0^=/ H0^ OH CH2 ._. ( yCH-CHj-NH-CH^ SCH, cH3-o-c-/~Vc-o—- Ch; ^-CH-CHj-NH-CH^ ^CH2 War 73 HO OH CH, fH3 ( ycH-CHj-NH-CH^ JCHj C-0-C-Qc-0--W ^ sCHr^ HC CH3 O ~ O O HO^^-C-0 "'' H0/~\c-0- Wó OH CH3 chj ^ ^CH-CHj-NH-C"^ sCH2 N Wzór 81 CH, HO O-6-0 .0-1-° HO-^yC-0 OH CrU CH? CH-CHj- NH- C s CH2 Wzór82 CH, HO OH ^^CH-Cr^-NH-C^ J0\ CH3 ^O^ Wzór 83 CH, o wo o -O—-i=/ Wzór HO OH CH3 CHz fyCH-CHj-NH^C ^ CH3-C-0^C O O Wzór84 ^2 OH CH3 CH2 CH-NH^C^ ^CH2 Wzór85 ^OU128 583 CH3 O o CH3-C-C-0- i-C-0-Qi-Ov OH CH3 CH2 S rCH-CH2-NH-^C CH3-C - C-0-^Vc-Q-^^ CH2 CH3 O J Wzór 85 CHs O O ;» fyc-o--^^ oh ch3 ch2 '3 O"C_0"~^ * CH2^ CH3—C— C-0 O Wzór 87 CH3 O HO-c-fyt-O^OH f*^ \=/ •/ A ru_ru.~NH-C ^T^CH-CH.-NH-CC 2 c_0_3=/ CH2 w-cO*-0 ^88 o 0o CH3-0-C- PL PL PL PL
Claims (1)
1.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8022440 | 1980-07-09 | ||
| GB8116440 | 1981-05-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL235908A1 PL235908A1 (pl) | 1982-10-25 |
| PL128583B1 true PL128583B1 (en) | 1984-02-29 |
Family
ID=26276163
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1981235908A PL128583B1 (en) | 1980-07-09 | 1981-07-08 | Method of obtaining new derivatives of 1-phenyl ethanol |
| PL1981235909A PL128584B1 (en) | 1980-07-09 | 1981-07-08 | Method of obtaining new derivatives of 1-phenyl ethanol |
| PL1981232109A PL128517B1 (en) | 1980-07-09 | 1981-07-08 | Method of obtaining new derivatives of 1-phenyl ethanol |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1981235909A PL128584B1 (en) | 1980-07-09 | 1981-07-08 | Method of obtaining new derivatives of 1-phenyl ethanol |
| PL1981232109A PL128517B1 (en) | 1980-07-09 | 1981-07-08 | Method of obtaining new derivatives of 1-phenyl ethanol |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4442300A (pl) |
| EP (1) | EP0046144B1 (pl) |
| KR (1) | KR850000800B1 (pl) |
| AU (1) | AU542776B2 (pl) |
| CA (1) | CA1210021A (pl) |
| CS (3) | CS221848B2 (pl) |
| CY (1) | CY1271A (pl) |
| DD (1) | DD202002A5 (pl) |
| DE (1) | DE3163114D1 (pl) |
| DK (1) | DK151797C (pl) |
| ES (3) | ES8300675A1 (pl) |
| FI (1) | FI812159A7 (pl) |
| GR (1) | GR74330B (pl) |
| HK (1) | HK93184A (pl) |
| HU (1) | HU183511B (pl) |
| IE (1) | IE51372B1 (pl) |
| IS (1) | IS1263B6 (pl) |
| MY (1) | MY8700201A (pl) |
| NO (2) | NO150153C (pl) |
| NZ (1) | NZ197627A (pl) |
| PH (2) | PH16929A (pl) |
| PL (3) | PL128583B1 (pl) |
| PT (1) | PT73335B (pl) |
| SG (1) | SG65684G (pl) |
| SU (3) | SU1128831A3 (pl) |
| YU (3) | YU170381A (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8615995D0 (en) * | 1986-07-01 | 1986-08-06 | Glaxo Group Ltd | Veterinary preparations |
| US5631375A (en) * | 1992-04-10 | 1997-05-20 | Merrell Pharmaceuticals, Inc. | Process for piperidine derivatives |
| US5654433A (en) * | 1993-01-26 | 1997-08-05 | Merrell Pharmaceuticals Inc. | Process for piperidine derivatives |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE335359B (pl) * | 1966-10-19 | 1971-05-24 | Draco Ab | |
| GB1298771A (en) * | 1969-04-01 | 1972-12-06 | Sterling Drug Inc | Carboxylic esters of hydroxyphenylalkanolamines |
| US4035405A (en) * | 1976-07-09 | 1977-07-12 | Interx Research Corporation | Novel synthesis for preparing the hydrochloride salt of selected catecholamine derivatives |
| US4145441A (en) * | 1977-11-04 | 1979-03-20 | Interx Research Corporation | Sympathomimetic amines exhibiting anti-hemorrhoidal activity |
-
1981
- 1981-06-30 EP EP81850118A patent/EP0046144B1/en not_active Expired
- 1981-06-30 DE DE8181850118T patent/DE3163114D1/de not_active Expired
- 1981-06-30 CY CY1271A patent/CY1271A/xx unknown
- 1981-07-01 US US06/279,467 patent/US4442300A/en not_active Expired - Fee Related
- 1981-07-07 NZ NZ197627A patent/NZ197627A/en unknown
- 1981-07-07 AU AU72629/81A patent/AU542776B2/en not_active Ceased
- 1981-07-07 IE IE1521/81A patent/IE51372B1/en unknown
- 1981-07-07 NO NO812312A patent/NO150153C/no unknown
- 1981-07-07 DK DK300681A patent/DK151797C/da not_active IP Right Cessation
- 1981-07-07 PH PH25870A patent/PH16929A/en unknown
- 1981-07-08 HU HU811987A patent/HU183511B/hu unknown
- 1981-07-08 PT PT73335A patent/PT73335B/pt unknown
- 1981-07-08 CS CS821229A patent/CS221848B2/cs unknown
- 1981-07-08 IS IS2658A patent/IS1263B6/is unknown
- 1981-07-08 ES ES503767A patent/ES8300675A1/es not_active Expired
- 1981-07-08 FI FI812159A patent/FI812159A7/fi not_active Application Discontinuation
- 1981-07-08 SU SU813308460A patent/SU1128831A3/ru active
- 1981-07-08 PL PL1981235908A patent/PL128583B1/pl unknown
- 1981-07-08 CA CA000381320A patent/CA1210021A/en not_active Expired
- 1981-07-08 PL PL1981235909A patent/PL128584B1/pl unknown
- 1981-07-08 CS CS815266A patent/CS221846B2/cs unknown
- 1981-07-08 PL PL1981232109A patent/PL128517B1/pl unknown
- 1981-07-08 CS CS821715A patent/CS221847B2/cs unknown
- 1981-07-09 GR GR65454A patent/GR74330B/el unknown
- 1981-07-09 DD DD81231627A patent/DD202002A5/de unknown
- 1981-07-09 YU YU01703/81A patent/YU170381A/xx unknown
- 1981-07-09 KR KR1019810002489A patent/KR850000800B1/ko not_active Expired
-
1982
- 1982-04-13 SU SU823419899A patent/SU1205759A3/ru active
- 1982-04-13 SU SU823419745A patent/SU1205758A3/ru active
- 1982-06-08 ES ES512920A patent/ES512920A0/es active Granted
- 1982-06-08 ES ES512921A patent/ES8304532A1/es not_active Expired
- 1982-07-01 PH PH27518A patent/PH17597A/en unknown
-
1983
- 1983-04-15 YU YU00865/83A patent/YU86583A/xx unknown
- 1983-04-15 YU YU00866/83A patent/YU86683A/xx unknown
- 1983-09-15 NO NO833321A patent/NO151962C/no unknown
-
1984
- 1984-09-13 SG SG65684A patent/SG65684G/en unknown
- 1984-11-29 HK HK931/84A patent/HK93184A/xx unknown
-
1987
- 1987-12-30 MY MY201/87A patent/MY8700201A/xx unknown
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