PL126161B1 - Method of manufacture of novel derivatives of phenylpiperazine - Google Patents

Method of manufacture of novel derivatives of phenylpiperazine

Info

Publication number
PL126161B1
PL126161B1 PL1980222294A PL22229480A PL126161B1 PL 126161 B1 PL126161 B1 PL 126161B1 PL 1980222294 A PL1980222294 A PL 1980222294A PL 22229480 A PL22229480 A PL 22229480A PL 126161 B1 PL126161 B1 PL 126161B1
Authority
PL
Poland
Prior art keywords
piperazine
ethyl
formula
compound
mmol
Prior art date
Application number
PL1980222294A
Other languages
English (en)
Polish (pl)
Other versions
PL222294A1 (,
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of PL222294A1 publication Critical patent/PL222294A1/xx
Publication of PL126161B1 publication Critical patent/PL126161B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
PL1980222294A 1979-03-01 1980-02-27 Method of manufacture of novel derivatives of phenylpiperazine PL126161B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7901633 1979-03-01

Publications (2)

Publication Number Publication Date
PL222294A1 PL222294A1 (,) 1980-12-01
PL126161B1 true PL126161B1 (en) 1983-07-30

Family

ID=19832723

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1980222294A PL126161B1 (en) 1979-03-01 1980-02-27 Method of manufacture of novel derivatives of phenylpiperazine

Country Status (20)

Country Link
EP (1) EP0015615B1 (,)
JP (1) JPS55141478A (,)
AT (1) ATE2219T1 (,)
AU (1) AU532411B2 (,)
CA (1) CA1138461A (,)
CS (1) CS216525B2 (,)
DD (1) DD151408A5 (,)
DE (1) DE3061561D1 (,)
DK (1) DK84380A (,)
ES (3) ES488988A0 (,)
FI (1) FI800588A7 (,)
GR (1) GR67005B (,)
HU (1) HU182070B (,)
IE (1) IE49526B1 (,)
IL (1) IL59489A (,)
PH (1) PH17025A (,)
PL (1) PL126161B1 (,)
SU (1) SU1039442A3 (,)
YU (1) YU54680A (,)
ZA (1) ZA801119B (,)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8005131A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met analgetische werking.
NL8005133A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met antiagressieve werking.
US4457931A (en) * 1982-09-27 1984-07-03 Selvi & C. S.P.A. Piperazine derivatives with anticholinergic and/or antihistaminic activity
JPH0660160B2 (ja) * 1985-12-13 1994-08-10 テルモ株式会社 アミド誘導体およびこれを含有する抗アレルギ−剤
FI93832C (fi) * 1989-04-22 1995-06-12 Wyeth John & Brother Ltd Menetelmä terapeuttisesti aktiivisten piperatsiniijohdannaisten valmistamiseksi
US5340812A (en) * 1989-04-22 1994-08-23 John Wyeth & Brother, Limited Piperazine derivatives
HUT54666A (en) * 1989-04-22 1991-03-28 Wyeth John & Brother Ltd Process for producing peperazine derivatives and pharmaceutical compositions containing them
US5382583A (en) * 1989-04-22 1995-01-17 John Wyeth & Brother, Limited Piperazine derivatives
DK203990D0 (da) * 1990-08-24 1990-08-24 Novo Nordisk As Piperazinylderivater
GB9200293D0 (en) * 1992-01-08 1992-02-26 Wyeth John & Brother Ltd Piperazine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2833770A (en) * 1958-05-06 Chj-chj
US2722529A (en) * 1955-11-01 Amides of certain l-amevoalkyl-x-phenyl
BE788280A (fr) * 1971-09-04 1973-02-28 Pfizer Nouvelles 1-(3-trifluoro-methyl-phenyl)-4-((amido cyclique)- alkyl) piperazines et composition pharmaceutique les contenant
GB1443598A (en) * 1973-07-06 1976-07-21 Acraf 1- 3-acetylaminopropyl-4-2,5-dichlorophenyl-piperazine
FR2306694A1 (fr) * 1975-04-07 1976-11-05 Parcor Derives de la piperazine

Also Published As

Publication number Publication date
ES495106A0 (es) 1981-11-16
ES8106898A1 (es) 1981-09-01
HU182070B (en) 1983-12-28
ZA801119B (en) 1981-09-30
YU54680A (en) 1983-09-30
ES488988A0 (es) 1981-09-01
PH17025A (en) 1984-05-17
CA1138461A (en) 1982-12-28
DD151408A5 (de) 1981-10-21
CS216525B2 (en) 1982-11-26
IL59489A (en) 1984-05-31
EP0015615B1 (en) 1983-01-12
FI800588A7 (fi) 1981-01-01
DK84380A (da) 1980-09-02
GR67005B (,) 1981-05-18
EP0015615A1 (en) 1980-09-17
SU1039442A3 (ru) 1983-08-30
DE3061561D1 (en) 1983-02-17
AU532411B2 (en) 1983-09-29
PL222294A1 (,) 1980-12-01
ES8200883A1 (es) 1981-11-16
IE49526B1 (en) 1985-10-16
JPS55141478A (en) 1980-11-05
IE800405L (en) 1980-09-01
AU5584880A (en) 1980-09-04
IL59489A0 (en) 1980-05-30
ES495105A0 (es) 1981-11-16
ES8200884A1 (es) 1981-11-16
ATE2219T1 (de) 1983-01-15

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