PH27014A - Compounds for the treatment of urinary incontinence - Google Patents
Compounds for the treatment of urinary incontinence Download PDFInfo
- Publication number
- PH27014A PH27014A PH39454A PH39454A PH27014A PH 27014 A PH27014 A PH 27014A PH 39454 A PH39454 A PH 39454A PH 39454 A PH39454 A PH 39454A PH 27014 A PH27014 A PH 27014A
- Authority
- PH
- Philippines
- Prior art keywords
- compounds
- lower alkyl
- diphenylacetamide
- methyl
- compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract description 72
- 238000011282 treatment Methods 0.000 title abstract description 16
- 206010046543 Urinary incontinence Diseases 0.000 title description 4
- 239000000203 mixture Substances 0.000 claims abstract description 30
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 22
- 210000003932 urinary bladder Anatomy 0.000 claims abstract description 18
- 239000001257 hydrogen Substances 0.000 claims abstract description 13
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 13
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract description 12
- 150000003839 salts Chemical class 0.000 claims abstract description 12
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims abstract description 11
- 239000002253 acid Substances 0.000 claims abstract description 9
- 125000003545 alkoxy group Chemical group 0.000 claims abstract description 9
- 150000007513 acids Chemical class 0.000 claims abstract description 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 6
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 5
- 230000003287 optical effect Effects 0.000 claims abstract description 5
- 125000004433 nitrogen atom Chemical group N* 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 claims description 16
- DLFVBJFMPXGRIB-UHFFFAOYSA-N thioacetamide Natural products CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 claims description 6
- 239000003937 drug carrier Substances 0.000 claims description 4
- GSCHLPMNNOMSNR-UHFFFAOYSA-N n-[2-[di(propan-2-yl)amino]ethyl]-2,2-diphenylacetamide Chemical compound C=1C=CC=CC=1C(C(=O)NCCN(C(C)C)C(C)C)C1=CC=CC=C1 GSCHLPMNNOMSNR-UHFFFAOYSA-N 0.000 claims description 4
- 239000008194 pharmaceutical composition Substances 0.000 claims description 4
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims description 3
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims description 2
- 125000004432 carbon atom Chemical group C* 0.000 claims description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 6
- 208000035475 disorder Diseases 0.000 abstract description 6
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract description 3
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- QPGRDTXELAFGRG-UHFFFAOYSA-N n',n'-di(propan-2-yl)propane-1,3-diamine Chemical compound CC(C)N(C(C)C)CCCN QPGRDTXELAFGRG-UHFFFAOYSA-N 0.000 description 1
- CVJLDKIKUUHTIA-UHFFFAOYSA-N n'-tert-butyl-n,n'-dimethylpropane-1,3-diamine Chemical compound CNCCCN(C)C(C)(C)C CVJLDKIKUUHTIA-UHFFFAOYSA-N 0.000 description 1
- NGRXSVVLBWDAHG-UHFFFAOYSA-N n,n-bis(propan-2-ylamino)ethanamine Chemical compound CC(C)NN(CC)NC(C)C NGRXSVVLBWDAHG-UHFFFAOYSA-N 0.000 description 1
- DBVADBHSJCWFKI-UHFFFAOYSA-N n-(2-chloroethyl)-n-propan-2-ylpropan-2-amine Chemical compound CC(C)N(C(C)C)CCCl DBVADBHSJCWFKI-UHFFFAOYSA-N 0.000 description 1
- CWEZWUZFIMDYDQ-UHFFFAOYSA-N n-(2-hydroxyethyl)-n-methyl-2,2-diphenylacetamide Chemical compound C=1C=CC=CC=1C(C(=O)N(CCO)C)C1=CC=CC=C1 CWEZWUZFIMDYDQ-UHFFFAOYSA-N 0.000 description 1
- ZGUQMUHCSSFERG-UHFFFAOYSA-N n-[2-[di(propan-2-yl)amino]ethyl]-2-(2-hydroxyphenyl)-2-phenylacetamide;hydrochloride Chemical compound Cl.C=1C=CC=C(O)C=1C(C(=O)NCCN(C(C)C)C(C)C)C1=CC=CC=C1 ZGUQMUHCSSFERG-UHFFFAOYSA-N 0.000 description 1
- SQWLHWBNQRMCBT-UHFFFAOYSA-N n-[2-[di(propan-2-yl)amino]ethyl]-2-methoxy-2,2-diphenylacetamide;hydrochloride Chemical compound Cl.C=1C=CC=CC=1C(C(=O)NCCN(C(C)C)C(C)C)(OC)C1=CC=CC=C1 SQWLHWBNQRMCBT-UHFFFAOYSA-N 0.000 description 1
- GUNXZCRBPCEOLU-UHFFFAOYSA-N n-[2-[di(propan-2-yl)amino]ethyl]-n-methyl-2,2-diphenylacetamide Chemical compound C=1C=CC=CC=1C(C(=O)N(C)CCN(C(C)C)C(C)C)C1=CC=CC=C1 GUNXZCRBPCEOLU-UHFFFAOYSA-N 0.000 description 1
- UARPOSDIKLYISH-UHFFFAOYSA-N n-[3-(diethylamino)propyl]-n-methyl-2,2-diphenylacetamide Chemical compound C=1C=CC=CC=1C(C(=O)N(C)CCCN(CC)CC)C1=CC=CC=C1 UARPOSDIKLYISH-UHFFFAOYSA-N 0.000 description 1
- 238000001783 near-resonance Rayleigh scattering spectroscopy Methods 0.000 description 1
- 150000002825 nitriles Chemical class 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000014571 nuts Nutrition 0.000 description 1
- 210000004789 organ system Anatomy 0.000 description 1
- 239000012044 organic layer Substances 0.000 description 1
- 229960005434 oxybutynin Drugs 0.000 description 1
- 210000003540 papillary muscle Anatomy 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 125000003386 piperidinyl group Chemical group 0.000 description 1
- 125000005936 piperidyl group Chemical group 0.000 description 1
- 210000003240 portal vein Anatomy 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 150000003141 primary amines Chemical class 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 229940080818 propionamide Drugs 0.000 description 1
- 210000001747 pupil Anatomy 0.000 description 1
- 239000002287 radioligand Substances 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000011369 resultant mixture Substances 0.000 description 1
- 229910052703 rhodium Inorganic materials 0.000 description 1
- 239000010948 rhodium Substances 0.000 description 1
- MHOVAHRLVXNVSD-UHFFFAOYSA-N rhodium atom Chemical compound [Rh] MHOVAHRLVXNVSD-UHFFFAOYSA-N 0.000 description 1
- 235000002020 sage Nutrition 0.000 description 1
- 208000026451 salivation Diseases 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- ODZPKZBBUMBTMG-UHFFFAOYSA-N sodium amide Chemical compound [NH2-].[Na+] ODZPKZBBUMBTMG-UHFFFAOYSA-N 0.000 description 1
- 229940080313 sodium starch Drugs 0.000 description 1
- PVGBHEUCHKGFQP-UHFFFAOYSA-N sodium;n-[5-amino-2-(4-aminophenyl)sulfonylphenyl]sulfonylacetamide Chemical compound [Na+].CC(=O)NS(=O)(=O)C1=CC(N)=CC=C1S(=O)(=O)C1=CC=C(N)C=C1 PVGBHEUCHKGFQP-UHFFFAOYSA-N 0.000 description 1
- 239000008279 sol Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000001148 spastic effect Effects 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000006794 tachycardia Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 208000026533 urinary bladder disease Diseases 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 210000001186 vagus nerve Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/40—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Table Equipment (AREA)
- Finger-Pressure Massage (AREA)
- Dowels (AREA)
- Underground Structures, Protecting, Testing And Restoring Foundations (AREA)
- Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Medicinal Preparation (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Discharge Heating (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8804003A SE8804003D0 (sv) | 1988-11-04 | 1988-11-04 | Compounds for the treatment of urinary incontinence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH27014A true PH27014A (en) | 1993-02-01 |
Family
ID=20373858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH39454A PH27014A (en) | 1988-11-04 | 1989-11-03 | Compounds for the treatment of urinary incontinence |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0367040B1 (ja) |
| JP (1) | JPH02218652A (ja) |
| KR (1) | KR900007407A (ja) |
| CN (1) | CN1043700A (ja) |
| AT (1) | ATE88460T1 (ja) |
| AU (1) | AU628879B2 (ja) |
| CA (1) | CA2001641A1 (ja) |
| DD (1) | DD289467A5 (ja) |
| DE (1) | DE68906122T2 (ja) |
| DK (1) | DK544689A (ja) |
| ES (1) | ES2054980T3 (ja) |
| FI (1) | FI895229A0 (ja) |
| HU (1) | HU202828B (ja) |
| IE (1) | IE63480B1 (ja) |
| NO (1) | NO894384L (ja) |
| NZ (1) | NZ231243A (ja) |
| PH (1) | PH27014A (ja) |
| PT (1) | PT92189B (ja) |
| RU (1) | RU1833370C (ja) |
| SE (1) | SE8804003D0 (ja) |
| TW (1) | TW197944B (ja) |
| ZA (1) | ZA898385B (ja) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5066680A (en) * | 1989-02-14 | 1991-11-19 | Fujisawa Pharmaceutical Co., Ltd. | Novel substituted-acetamide compound and a process for the preparation thereof |
| US5192779A (en) * | 1989-02-14 | 1993-03-09 | Fujisawa Pharmaceutical Co., Ltd. | Substituted-acetamide compound and a process for the preparation thereof |
| PH30083A (en) * | 1991-02-25 | 1996-12-27 | Lilly Co Eli | Treatment of lower urinary tract disorders |
| TW344661B (en) * | 1993-11-24 | 1998-11-11 | Lilly Co Eli | Pharmaceutical composition for treatment of incontinence |
| GB0328060D0 (en) * | 2003-12-04 | 2004-01-07 | Sod Conseils Rech Applic | Botulinum toxin treatment |
| MX368097B (es) * | 2015-04-28 | 2019-09-19 | Unilever Nv | Compuestos de n-aralquilcarbonildiamina y composiciones para el cuidado personal que comprende los mismos. |
| EP3288926B1 (en) | 2015-04-28 | 2021-01-20 | Unilever PLC | N-aralkylcarbonyl-piperazine and -homopiperazine compounds and personal care compositions comprising the same |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2009144A (en) * | 1935-07-23 | Substituted amides of amphatic- | ||
| US2831892A (en) * | 1956-03-22 | 1958-04-22 | Searle & Co | N-(3-isopropylaminopropyl) diphenyl-acetamide and processes |
| FR2319337A1 (fr) * | 1975-07-30 | 1977-02-25 | Fabre Sa Pierre | Gem diaryles possedant une activite antiarythmique utile en therapeutique cardiovasculaire |
| FR2333501A2 (fr) * | 1975-12-03 | 1977-07-01 | Science Union & Cie | Nouveaux acetamides substitues leurs procedes d'obtention et les compositions pharmaceutiques en renfermant |
| FR2340724A2 (fr) * | 1976-02-13 | 1977-09-09 | Science Union & Cie | Nouveaux diarylacetamides substitues, leurs procedes de preparation et les compositions pharmaceutiques en contenant |
| FR2421892A1 (fr) * | 1977-10-17 | 1979-11-02 | Fabre Sa Pierre | Procede de synthese industrielle du n(n' ethyl pyrrolidino-2 methyl) aadiphenylahydroxy acetamide |
| FR2421891A1 (fr) * | 1977-10-17 | 1979-11-02 | Fabre Sa Pierre | Obtention industrielle d'amides de la pyrrolidine ethyl amine |
| US5066680A (en) * | 1989-02-14 | 1991-11-19 | Fujisawa Pharmaceutical Co., Ltd. | Novel substituted-acetamide compound and a process for the preparation thereof |
-
1988
- 1988-11-04 SE SE8804003A patent/SE8804003D0/xx unknown
-
1989
- 1989-10-20 ES ES89119480T patent/ES2054980T3/es not_active Expired - Lifetime
- 1989-10-20 AT AT89119480T patent/ATE88460T1/de not_active IP Right Cessation
- 1989-10-20 IE IE339889A patent/IE63480B1/en not_active IP Right Cessation
- 1989-10-20 EP EP89119480A patent/EP0367040B1/en not_active Expired - Lifetime
- 1989-10-20 DE DE68906122T patent/DE68906122T2/de not_active Expired - Fee Related
- 1989-10-27 CA CA002001641A patent/CA2001641A1/en not_active Abandoned
- 1989-11-01 DK DK544689A patent/DK544689A/da not_active Application Discontinuation
- 1989-11-02 HU HU895648A patent/HU202828B/hu unknown
- 1989-11-02 NZ NZ231243A patent/NZ231243A/en unknown
- 1989-11-02 JP JP1285092A patent/JPH02218652A/ja active Pending
- 1989-11-03 AU AU44394/89A patent/AU628879B2/en not_active Ceased
- 1989-11-03 NO NO89894384A patent/NO894384L/no unknown
- 1989-11-03 PT PT92189A patent/PT92189B/pt not_active IP Right Cessation
- 1989-11-03 ZA ZA898385A patent/ZA898385B/xx unknown
- 1989-11-03 DD DD89334233A patent/DD289467A5/de not_active IP Right Cessation
- 1989-11-03 PH PH39454A patent/PH27014A/en unknown
- 1989-11-03 RU SU894742370A patent/RU1833370C/ru active
- 1989-11-03 FI FI895229A patent/FI895229A0/fi not_active IP Right Cessation
- 1989-11-04 CN CN89109190A patent/CN1043700A/zh active Pending
- 1989-11-04 KR KR1019890016004A patent/KR900007407A/ko not_active Application Discontinuation
- 1989-12-19 TW TW078109850A patent/TW197944B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| PT92189B (pt) | 1995-07-18 |
| EP0367040B1 (en) | 1993-04-21 |
| CA2001641A1 (en) | 1990-05-04 |
| HU202828B (en) | 1991-04-29 |
| ZA898385B (en) | 1990-07-25 |
| HU895648D0 (en) | 1990-01-28 |
| NZ231243A (en) | 1994-03-25 |
| DE68906122T2 (de) | 1997-05-22 |
| ES2054980T3 (es) | 1994-08-16 |
| DD289467A5 (de) | 1991-05-02 |
| IE63480B1 (en) | 1995-05-03 |
| AU4439489A (en) | 1990-05-10 |
| SE8804003D0 (sv) | 1988-11-04 |
| FI895229A0 (fi) | 1989-11-03 |
| HUT51597A (en) | 1990-05-28 |
| JPH02218652A (ja) | 1990-08-31 |
| DK544689D0 (da) | 1989-11-01 |
| EP0367040A1 (en) | 1990-05-09 |
| KR900007407A (ko) | 1990-06-01 |
| TW197944B (ja) | 1993-01-11 |
| IE893398L (en) | 1990-05-04 |
| NO894384L (no) | 1990-05-07 |
| CN1043700A (zh) | 1990-07-11 |
| ATE88460T1 (de) | 1993-05-15 |
| DK544689A (da) | 1990-05-05 |
| NO894384D0 (no) | 1989-11-03 |
| DE68906122D1 (de) | 1993-05-27 |
| AU628879B2 (en) | 1992-09-24 |
| PT92189A (pt) | 1990-05-31 |
| RU1833370C (en) | 1993-08-07 |
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