PH25461A - Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides, pahrmaceutical composition containing said compound, method of use thereof - Google Patents

Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides, pahrmaceutical composition containing said compound, method of use thereof

Info

Publication number
PH25461A
PH25461A PH38563A PH38563A PH25461A PH 25461 A PH25461 A PH 25461A PH 38563 A PH38563 A PH 38563A PH 38563 A PH38563 A PH 38563A PH 25461 A PH25461 A PH 25461A
Authority
PH
Philippines
Prior art keywords
alkyl
imidazol
hydrogen
benzamides
substituted
Prior art date
Application number
PH38563A
Other languages
English (en)
Inventor
Eric Cossement
Jean Gobert
Philippe Michel
Ernst Wulfert
Jean-Pierre Geerts
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of PH25461A publication Critical patent/PH25461A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Lubricants (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
PH38563A 1988-04-28 1989-04-25 Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides, pahrmaceutical composition containing said compound, method of use thereof PH25461A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888810067A GB8810067D0 (en) 1988-04-28 1988-04-28 Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides

Publications (1)

Publication Number Publication Date
PH25461A true PH25461A (en) 1991-07-01

Family

ID=10636026

Family Applications (1)

Application Number Title Priority Date Filing Date
PH38563A PH25461A (en) 1988-04-28 1989-04-25 Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides, pahrmaceutical composition containing said compound, method of use thereof

Country Status (30)

Country Link
US (1) US4923865A (de)
EP (1) EP0341231B1 (de)
JP (1) JP2840288B2 (de)
KR (1) KR970011275B1 (de)
AT (1) ATE82571T1 (de)
AU (1) AU610796B2 (de)
BR (2) BR1100052A (de)
CA (1) CA1310966C (de)
CY (1) CY1758A (de)
DE (1) DE68903531T2 (de)
DK (1) DK205589A (de)
ES (1) ES2052969T3 (de)
FI (1) FI101791B1 (de)
GB (1) GB8810067D0 (de)
GR (1) GR3006836T3 (de)
HK (1) HK9494A (de)
HU (1) HU203877B (de)
IE (1) IE63698B1 (de)
IL (1) IL90087A0 (de)
LT (1) LT3671B (de)
LV (1) LV10437B (de)
MY (1) MY104084A (de)
NO (1) NO173331C (de)
NZ (1) NZ228897A (de)
PH (1) PH25461A (de)
PL (2) PL156250B1 (de)
PT (1) PT90368B (de)
RU (3) RU1830063C (de)
UA (1) UA12835A1 (de)
ZA (1) ZA893140B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9310965D0 (en) * 1993-05-27 1993-07-14 Ucb Sa 2-hydroxy-3-(1h-imidazol-4-yl)alkyl)benzenecarboximidamides
ATE234290T1 (de) * 1993-11-15 2003-03-15 Schering Corp Phenylalkyl-imidazole als h3-rezeptor- antagonisten
JP3294961B2 (ja) * 1993-12-10 2002-06-24 杏林製薬株式会社 新規イミダゾール誘導体及びその製造法
GB9521680D0 (en) * 1995-10-23 1996-01-03 Orion Yhtymo Oy New use of imidazole derivatives
DE10161818A1 (de) * 2001-12-14 2003-06-26 Gruenenthal Gmbh Substituierte 1,5-Diaminopentan-3-ol-Verbindungen
NZ554374A (en) * 2004-10-07 2010-11-26 Vitae Pharmaceuticals Inc Diaminoalkane aspartic protease inhibitors
TWI411607B (zh) * 2005-11-14 2013-10-11 Vitae Pharmaceuticals Inc 天門冬胺酸蛋白酶抑制劑
CL2007002689A1 (es) 2006-09-18 2008-04-18 Vitae Pharmaceuticals Inc Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
WO2009096996A1 (en) * 2007-06-20 2009-08-06 Smithkline Beecham Corporation Renin inhibitors
US20100160424A1 (en) * 2007-06-20 2010-06-24 Baldwin John J Renin inhibitors
US20090226549A1 (en) * 2008-03-06 2009-09-10 Kenneth John Hughes Herbal extracts and flavor systems for oral products and methods of making the same
EP2307396A1 (de) * 2008-06-20 2011-04-13 Vitae Pharmaceuticals, Inc. Renininhibitoren und verfahren zu deren anwendung
CA2729052A1 (en) * 2008-06-26 2009-12-30 Vitae Pharmaceuticals, Inc. Salts of methyl 2-((r)-(3-chlorophenyl)((r)-1-((s)-2-(methylamino)-3((r)-tetrahydro-2h-pyran-3-yl)propylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate
AR077692A1 (es) * 2009-08-06 2011-09-14 Vitae Pharmaceuticals Inc Sales de 2-((r)-(3-clorofenil) ((r)-1-((s) -2-(metilamino)-3-((r)-tetrahidro-2h-piran-3-il) propilcarbamoil) piperidin -3-il) metoxi) etilcarbamato de metilo
CA2825599C (en) 2011-02-01 2021-07-13 The Board Of Trustees Of The University Of Illinois 4-methyl-n-hydroxybenzamide compounds as histone deacetylase (hdac) inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU518569B2 (en) * 1979-08-07 1981-10-08 Farmos-Yhtyma Oy 4-benzyl- and 4-benzoyl imidazole derivatives
US4303485A (en) 1979-08-20 1981-12-01 Minnesota Mining And Manufacturing Company Ultraviolet polymerization of acrylate monomers using oxidizable tin compounds
GB2092569B (en) * 1981-02-05 1984-09-19 Farmos Oy Substituted imidazole derivatives and their preparation and use
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
DE3635700A1 (de) 1986-10-21 1988-04-28 Michael Schmeller Hubeinrichtung
GB8626287D0 (en) * 1986-11-04 1986-12-03 Ucb Sa Substituted 1h-imidazoles
GB8714013D0 (en) * 1987-06-16 1987-07-22 Ici Plc (substituted-aralkyl)heterocyclic compounds

Also Published As

Publication number Publication date
HU203877B (en) 1991-10-28
UA12835A1 (uk) 1997-02-28
ES2052969T3 (es) 1994-07-16
EP0341231A1 (de) 1989-11-08
NO173331C (no) 1993-12-08
HK9494A (en) 1994-02-09
FI101791B (fi) 1998-08-31
PT90368A (pt) 1989-11-10
LV10437A (lv) 1995-02-20
EP0341231B1 (de) 1992-11-19
NO173331B (no) 1993-08-23
MY104084A (en) 1993-11-30
BR1100064A (pt) 1999-12-07
GR3006836T3 (de) 1993-06-30
FI891975A (fi) 1989-10-29
JPH01313467A (ja) 1989-12-18
US4923865A (en) 1990-05-08
LTIP827A (en) 1995-02-27
ZA893140B (en) 1990-01-31
ATE82571T1 (de) 1992-12-15
CA1310966C (en) 1992-12-01
IE63698B1 (en) 1995-05-31
LT3671B (en) 1996-01-25
NO891760L (no) 1989-10-30
AU610796B2 (en) 1991-05-23
FI101791B1 (fi) 1998-08-31
BR1100052A (pt) 1999-12-07
DE68903531D1 (de) 1992-12-24
RU1836353C (ru) 1993-08-23
CY1758A (en) 1994-07-15
AU3373089A (en) 1989-11-02
IL90087A0 (en) 1989-12-15
IE891360L (en) 1989-10-28
DK205589A (da) 1989-10-29
DK205589D0 (da) 1989-04-27
RU1814647C (ru) 1993-05-07
DE68903531T2 (de) 1993-04-29
JP2840288B2 (ja) 1998-12-24
HUT51257A (en) 1990-04-28
PL161362B1 (pl) 1993-06-30
NZ228897A (en) 1990-08-28
KR890016017A (ko) 1989-11-28
LV10437B (en) 1996-04-20
RU1830063C (ru) 1993-07-23
PT90368B (pt) 1994-08-31
NO891760D0 (no) 1989-04-27
FI891975A0 (fi) 1989-04-26
KR970011275B1 (ko) 1997-07-09
PL156250B1 (pl) 1992-02-28
GB8810067D0 (en) 1988-06-02

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