PH24049A - Substituted benzamide derivatives and pharmaceutical compositions containing the same - Google Patents
Substituted benzamide derivatives and pharmaceutical compositions containing the sameInfo
- Publication number
- PH24049A PH24049A PH35203A PH35203A PH24049A PH 24049 A PH24049 A PH 24049A PH 35203 A PH35203 A PH 35203A PH 35203 A PH35203 A PH 35203A PH 24049 A PH24049 A PH 24049A
- Authority
- PH
- Philippines
- Prior art keywords
- same
- pharmaceutical compositions
- compositions containing
- benzamide derivatives
- substituted benzamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/10—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10155286 | 1986-04-30 | ||
| JP31509086 | 1986-12-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH24049A true PH24049A (en) | 1990-03-05 |
Family
ID=26442419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH35203A PH24049A (en) | 1986-04-30 | 1987-04-29 | Substituted benzamide derivatives and pharmaceutical compositions containing the same |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4870074A (h) |
| EP (1) | EP0243959B1 (h) |
| KR (1) | KR870010030A (h) |
| AR (1) | AR242953A1 (h) |
| AU (1) | AU592177B2 (h) |
| CA (1) | CA1291135C (h) |
| CZ (1) | CZ284687B6 (h) |
| DE (1) | DE3781195T2 (h) |
| DK (1) | DK175281B1 (h) |
| ES (1) | ES2043617T3 (h) |
| FI (1) | FI87776C (h) |
| GR (1) | GR3005934T3 (h) |
| HK (1) | HK18194A (h) |
| HU (1) | HU198193B (h) |
| NZ (1) | NZ220120A (h) |
| PH (1) | PH24049A (h) |
| SK (1) | SK279058B6 (h) |
| SU (1) | SU1597101A3 (h) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2640139A1 (fr) * | 1988-12-14 | 1990-06-15 | Delagrange Laboratoires | Application de benzamides substitues comme gastromoteurs |
| TW213460B (h) * | 1991-02-15 | 1993-09-21 | Hokuriku Pharmaceutical | |
| US5395832A (en) * | 1991-02-15 | 1995-03-07 | Hokuriku Seiyaku Co., Ltd. | Benzamide derivatives |
| US5864039A (en) * | 1994-03-30 | 1999-01-26 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzoic acid compounds and use thereof as medicaments |
| CA2186623A1 (en) * | 1994-03-30 | 1995-10-21 | Takeshi Kawakita | Benzoic acid compound and use thereof as medicine |
| DE69617001T2 (de) * | 1995-05-23 | 2002-07-11 | Janssen Pharmaceutica N.V., Beerse | (2-morpholinylmethyl)benzamid-derivate |
| JP2001064177A (ja) * | 1999-08-16 | 2001-03-13 | Schering Ag | ベンズアミド誘導体を有効成分とする製剤 |
| JP5089846B2 (ja) * | 2000-09-29 | 2012-12-05 | グラクソ グループ リミテッド | 炎症性疾患を処置するためのモルホリン−アセトアミド誘導体 |
| ES2234929T3 (es) * | 2000-11-28 | 2005-07-01 | Smithkline Beecham Plc | Derivados de morfolina como antagonistas de los receptores de orexina. |
| JP4829417B2 (ja) * | 2001-03-26 | 2011-12-07 | 明夫 乾 | インスリン抵抗性改善薬 |
| US20040265381A1 (en) * | 2001-10-08 | 2004-12-30 | Shanghvi Dilip S. | Anti-asthmatic drug (asmakure) from indigenous herbs to cure the disease asthma |
| GB0207447D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| GB0207449D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| GB0208158D0 (en) * | 2002-03-28 | 2002-05-22 | Glaxo Group Ltd | Novel compounds |
| HUP0201980A3 (en) * | 2002-06-13 | 2008-06-30 | Richter Gedeon Nyrt | Process for preparing a benzamide derivative and intermediates thereof |
| US8153161B2 (en) * | 2003-12-09 | 2012-04-10 | Dainippon Sumitomo Pharma Co., Ltd. | Medicament-containing particle and a solid preparation containing the particle |
| US8138204B2 (en) * | 2004-01-07 | 2012-03-20 | Aryx Therapeutics, Inc. | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| EP1704146B1 (en) * | 2004-01-07 | 2010-04-14 | Aryx Therapeutics | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| US8524736B2 (en) | 2004-01-07 | 2013-09-03 | Armetheon, Inc. | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| PT1801108E (pt) * | 2004-09-08 | 2012-12-03 | Mitsubishi Tanabe Pharma Corp | Composto de morfolina para o tratamento de inflamações |
| TWI391380B (zh) * | 2005-06-23 | 2013-04-01 | Array Biopharma Inc | 製備苯并咪唑化合物之方法 |
| US7326787B2 (en) * | 2005-08-31 | 2008-02-05 | Aryx Therapeutics, Inc. | Synthetic methods and intermediates for stereoisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders |
| US20090042926A1 (en) * | 2005-12-20 | 2009-02-12 | Jason Imbriglio | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment |
| KR100750593B1 (ko) * | 2006-03-16 | 2007-08-20 | 동우신테크 주식회사 | 치환된 벤즈아미드 유도체의 제조방법 |
| US20080085915A1 (en) * | 2006-06-23 | 2008-04-10 | Cyrus Becker | Compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| ES2524340T3 (es) * | 2007-04-19 | 2014-12-05 | Concert Pharmaceuticals Inc. | Compuestos de morfinilino deuterados |
| CN101402633A (zh) * | 2007-09-11 | 2009-04-08 | 上海恒瑞医药有限公司 | 苯甲酰胺类衍生物、其制备方法及其在医药上的用途 |
| ES2393640T3 (es) | 2008-02-13 | 2012-12-26 | Dainippon Sumitomo Pharma Co., Ltd. | Comprimidos bucodisgregables |
| TWI423967B (zh) * | 2008-02-21 | 2014-01-21 | Dainippon Sumitomo Pharma Co | 醯胺衍生物及含有其之醫藥組合物 |
| US8591955B2 (en) | 2009-08-11 | 2013-11-26 | Dainippon Sumitomo Pharma Co., Ltd. | Orally rapidly disintegrating tablet that contains two or more types of particles |
| WO2011107903A1 (en) | 2010-03-04 | 2011-09-09 | Ranbaxy Laboratories Limited | Highly pure mosapride citrate dihydrate and processes for its preparation |
| MX336155B (es) | 2011-02-25 | 2016-01-07 | Yuhan Corp | Derivados de diaminopirimidina y procesos para su preparacion. |
| KR101657616B1 (ko) | 2013-05-24 | 2016-09-19 | 주식회사유한양행 | 피리미딘 고리를 포함하는 바이사이클릭 유도체 및 그의 제조방법 |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| CN111349052B (zh) * | 2020-04-07 | 2021-02-12 | 福建海西新药创制有限公司 | 一种枸橼酸莫沙必利的合成方法 |
| CN114560822B (zh) * | 2020-11-27 | 2024-05-28 | 鲁南制药集团股份有限公司 | 一种莫沙必利的二羧酸晶体 |
| CN114591260B (zh) * | 2020-12-05 | 2025-07-11 | 鲁南制药集团股份有限公司 | 一种莫沙必利有机酸盐 |
| CN119241464A (zh) * | 2024-10-22 | 2025-01-03 | 吉林修正药业新药开发有限公司 | 一种枸橼酸莫沙必利杂质化合物及其制备方法 |
| CN119241463A (zh) * | 2024-10-22 | 2025-01-03 | 吉林修正药业新药开发有限公司 | 一种枸橼酸莫沙必利杂质化合物及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH451142A (de) * | 1965-01-19 | 1968-05-15 | Sandoz Ag | Verfahren zur Herstellung neuer basisch substituierter Benzoesäureamide |
| US4029786A (en) * | 1972-08-11 | 1977-06-14 | Imperial Chemical Industries Limited | Morpholine derivatives for treating depression |
| US4323503A (en) * | 1976-08-04 | 1982-04-06 | Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France | Substituted 2,3-alkylene di (oxy) benzamides and derivatives |
| US4210754A (en) * | 1977-02-01 | 1980-07-01 | Hoffmann-La Roche Inc. | Morpholino containing benzamides |
| US4692445A (en) * | 1983-04-29 | 1987-09-08 | Rorer Pharmaceutical Corporation | Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use |
| FR2575158B1 (fr) * | 1984-12-20 | 1987-10-02 | Pf Medicament | Arylalcoyloxymethyl-2 morpholines, leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central |
| JPH0390274A (ja) * | 1989-08-28 | 1991-04-16 | Furukawa Alum Co Ltd | Ａｌ又はＡｌ合金の気相ろう付法 |
-
1987
- 1987-04-24 US US07/042,474 patent/US4870074A/en not_active Expired - Lifetime
- 1987-04-24 CZ CS872897A patent/CZ284687B6/cs not_active IP Right Cessation
- 1987-04-24 SK SK2897-87A patent/SK279058B6/sk unknown
- 1987-04-27 FI FI871828A patent/FI87776C/fi not_active IP Right Cessation
- 1987-04-28 NZ NZ220120A patent/NZ220120A/xx unknown
- 1987-04-28 CA CA000535794A patent/CA1291135C/en not_active Expired - Lifetime
- 1987-04-29 DK DK198702187A patent/DK175281B1/da not_active IP Right Cessation
- 1987-04-29 SU SU874202484A patent/SU1597101A3/ru active
- 1987-04-29 EP EP87106266A patent/EP0243959B1/en not_active Expired - Lifetime
- 1987-04-29 PH PH35203A patent/PH24049A/en unknown
- 1987-04-29 HU HU871946A patent/HU198193B/hu unknown
- 1987-04-29 DE DE8787106266T patent/DE3781195T2/de not_active Expired - Lifetime
- 1987-04-29 ES ES87106266T patent/ES2043617T3/es not_active Expired - Lifetime
- 1987-04-30 KR KR870004220A patent/KR870010030A/ko not_active Withdrawn
- 1987-04-30 AR AR87307449A patent/AR242953A1/es active
- 1987-04-30 AU AU72275/87A patent/AU592177B2/en not_active Expired
-
1992
- 1992-10-12 GR GR920402254T patent/GR3005934T3/el unknown
-
1994
- 1994-03-03 HK HK181/94A patent/HK18194A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SU1597101A3 (ru) | 1990-09-30 |
| DK218787A (da) | 1987-10-31 |
| KR870010030A (ko) | 1987-11-30 |
| ES2043617T3 (es) | 1994-01-01 |
| US4870074A (en) | 1989-09-26 |
| FI871828A0 (fi) | 1987-04-27 |
| DK175281B1 (da) | 2004-08-09 |
| NZ220120A (en) | 1989-06-28 |
| FI871828A7 (fi) | 1987-10-31 |
| EP0243959A1 (en) | 1987-11-04 |
| DK218787D0 (da) | 1987-04-29 |
| AR242953A1 (es) | 1993-06-30 |
| SK289787A3 (en) | 1998-06-03 |
| CZ284687B6 (cs) | 1999-02-17 |
| CZ289787A3 (cs) | 1998-11-11 |
| FI87776B (fi) | 1992-11-13 |
| HK18194A (en) | 1994-03-11 |
| AU7227587A (en) | 1987-11-05 |
| DE3781195T2 (de) | 1993-02-18 |
| GR3005934T3 (h) | 1993-06-07 |
| HU198193B (en) | 1989-08-28 |
| FI87776C (fi) | 1993-02-25 |
| DE3781195D1 (de) | 1992-09-24 |
| EP0243959B1 (en) | 1992-08-19 |
| SK279058B6 (sk) | 1998-06-03 |
| AU592177B2 (en) | 1990-01-04 |
| CA1291135C (en) | 1991-10-22 |
| HUT45514A (en) | 1988-07-28 |
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