PH22821A - Phenyl butenamide, pharmaceutical composition containing said compound and method of use thereof - Google Patents

Phenyl butenamide, pharmaceutical composition containing said compound and method of use thereof

Info

Publication number
PH22821A
PH22821A PH35615A PH35615A PH22821A PH 22821 A PH22821 A PH 22821A PH 35615 A PH35615 A PH 35615A PH 35615 A PH35615 A PH 35615A PH 22821 A PH22821 A PH 22821A
Authority
PH
Philippines
Prior art keywords
butenamide
phenyl
compound
pharmaceutical composition
composition containing
Prior art date
Application number
PH35615A
Other languages
English (en)
Inventor
Gallagher Peter Thaddeus
Hicks Terence Alan
Mullier Graham Walter
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of PH22821A publication Critical patent/PH22821A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C07D261/16—Benzene-sulfonamido isoxazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
PH35615A 1986-08-08 1987-08-03 Phenyl butenamide, pharmaceutical composition containing said compound and method of use thereof PH22821A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868619432A GB8619432D0 (en) 1986-08-08 1986-08-08 Pharmaceutical compounds

Publications (1)

Publication Number Publication Date
PH22821A true PH22821A (en) 1989-01-19

Family

ID=10602473

Family Applications (1)

Application Number Title Priority Date Filing Date
PH35615A PH22821A (en) 1986-08-08 1987-08-03 Phenyl butenamide, pharmaceutical composition containing said compound and method of use thereof

Country Status (23)

Country Link
US (1) US4892963A (de)
EP (1) EP0257882B1 (de)
JP (1) JPS63239259A (de)
KR (2) KR880002823A (de)
CN (1) CN1015256B (de)
AR (2) AR244660A1 (de)
AT (1) ATE65494T1 (de)
AU (1) AU604737B2 (de)
CA (1) CA1317964C (de)
DE (1) DE3771611D1 (de)
DK (1) DK169404B1 (de)
EG (1) EG18269A (de)
ES (1) ES2031510T3 (de)
GB (1) GB8619432D0 (de)
GR (1) GR3002714T3 (de)
HU (1) HU197559B (de)
IL (1) IL83432A (de)
MX (1) MX174371B (de)
NZ (1) NZ221352A (de)
PH (1) PH22821A (de)
PT (1) PT85476B (de)
RU (1) RU1771472C (de)
ZA (1) ZA875813B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3534440A1 (de) * 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
US5268382A (en) * 1985-09-27 1993-12-07 Hoechst Aktiengesellschaft Medicaments to combat autoimmune diseases, in particular systemic lupus erythematosus
US4975462A (en) * 1988-07-29 1990-12-04 Bristol-Myers Company Antiarthritic α-arylcarbamoyl cyanoacetic acid derivatives
US5583150A (en) * 1989-08-18 1996-12-10 Alcon Laboratories, Inc. 5-methyl-isoxazole-4-carboxylic acid anilides and 2-hydroxyethylidene-cyano acetic anilides for the treatment of ocular diseases
DD297328A5 (de) * 1989-08-18 1992-01-09 �������@���������k���Kk�� 5-methyl-isoxalol-4-carbonsaeureanilide und 2 hydroxyethyliden-cyanoessigsaeureanilide zur behandlung von augenerkrankungen
US5001124A (en) * 1990-02-02 1991-03-19 Syntex (U.S.A.) Inc. 4-isoxazolecarboxamide derivatives
US5108999A (en) * 1990-02-02 1992-04-28 Syntex (U.S.A.) Inc. 4-isoxazolecarboxamide derivatives
JPH04211048A (ja) * 1990-03-05 1992-08-03 Mitsubishi Kasei Corp チオカルバモイルアセトニトリル誘導体
US5494911A (en) * 1990-05-18 1996-02-27 Hoechst Aktiengesellschaft Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides, pharmaceuticals containing these compounds and their use
IL102790A (en) * 1991-09-17 1996-01-31 Roussel Uclaf History of 3-cycloalkyl-prop-2-anamide
ES2079765T3 (es) * 1991-10-23 1996-01-16 Hoechst Ag Derivados de amidas de acido n-fenil-2-ciano-3-hidroxicrotonico y su utilizacion como medicamento con propiedad inmunomoduladora.
GB9200275D0 (en) * 1992-01-08 1992-02-26 Roussel Lab Ltd Chemical compounds
TW314467B (de) * 1993-03-31 1997-09-01 Hoechst Ag
WO1994024095A1 (en) * 1993-04-16 1994-10-27 Abbott Laboratories Immunosuppressive agents
GB9320299D0 (en) * 1993-10-01 1993-11-17 Roussel Lab Ltd Isoxazole derivatives
DK0787491T3 (da) * 1994-10-17 2000-10-16 Aventis Pharma Ltd Middel til forebyggelse og behandling af allergiske sygdomme af type I
DE19702988A1 (de) * 1997-01-28 1998-07-30 Hoechst Ag Isoxazol- und Crotonsäureamidderivate und deren Verwendung als Arzneimittel und Diagnostika
IL149792A0 (en) * 1999-12-16 2002-11-10 Teva Pharma Novel processes for making and a new crystalline form of leflunomide
ES2237553T3 (es) 2000-02-15 2005-08-01 Teva Pharmaceutical Industries Ltd. Procedimiento para la sintesis de leflunomida.
US6894184B2 (en) 2003-03-18 2005-05-17 Aventis Pharma Deutschland Gmbh Process for preparing 2-cyano-3-hydroxy-N-(phenyl)but-2-enamides
DE10311763A1 (de) * 2003-03-18 2004-10-07 Aventis Pharma Deutschland Gmbh Verfahren zur Herstellung von 2-Cyan-3-hydroxy-N-(phenyl)but-2-enamiden
JP2016537360A (ja) 2013-11-22 2016-12-01 ジェンザイム・コーポレーション 神経変性疾患を治療するための新規な方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL186239B (nl) * 1975-06-05 Hoechst Ag Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze.
DK545976A (da) * 1975-12-11 1977-06-12 Hoechst Ag Cyaneddikesyreanilidderivater fremgangsmade til deres fremstilling og midler der indeholder disse forbindelser
DE2654797A1 (de) * 1976-12-03 1978-06-08 Hoechst Ag Verfahren zur herstellung von isoxazolderivaten
DE2655009A1 (de) * 1976-12-04 1978-06-15 Hoechst Ag Isoxazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
FI71129C (fi) * 1979-06-11 1986-11-24 Ciba Geigy Ag Foerfarande foer framstaellning av farmaceutiskt aktiva alfakarbamoylpyrrolpropionitriler

Also Published As

Publication number Publication date
DK169404B1 (da) 1994-10-24
US4892963A (en) 1990-01-09
EG18269A (en) 1992-12-30
PT85476B (pt) 1990-06-29
ZA875813B (en) 1989-04-26
IL83432A (en) 1992-06-21
GR3002714T3 (en) 1993-01-25
HUT44523A (en) 1988-03-28
RU1771472C (ru) 1992-10-23
PT85476A (en) 1987-09-01
AR244660A1 (es) 1993-11-30
CA1317964C (en) 1993-05-18
DK413987A (da) 1988-02-09
GB8619432D0 (en) 1986-09-17
AR247876A1 (es) 1995-04-28
EP0257882A1 (de) 1988-03-02
CN1015256B (zh) 1992-01-01
KR880002815A (ko) 1988-05-11
MX174371B (es) 1994-05-11
EP0257882B1 (de) 1991-07-24
IL83432A0 (en) 1988-01-31
HU197559B (en) 1989-04-28
KR880002823A (ko) 1988-05-11
NZ221352A (en) 1989-10-27
DK413987D0 (da) 1987-08-07
ES2031510T3 (es) 1992-12-16
CN87105516A (zh) 1988-02-24
MX7668A (es) 1993-08-01
JPS63239259A (ja) 1988-10-05
DE3771611D1 (de) 1991-08-29
ATE65494T1 (de) 1991-08-15
AU604737B2 (en) 1991-01-03
AU7668187A (en) 1988-02-11

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