DK413987A - Substitueret phenylamidforbindelse - Google Patents
Substitueret phenylamidforbindelseInfo
- Publication number
- DK413987A DK413987A DK413987A DK413987A DK413987A DK 413987 A DK413987 A DK 413987A DK 413987 A DK413987 A DK 413987A DK 413987 A DK413987 A DK 413987A DK 413987 A DK413987 A DK 413987A
- Authority
- DK
- Denmark
- Prior art keywords
- phenylamide compound
- substituted phenylamide
- substituted
- compound
- phenylamide
- Prior art date
Links
- -1 PHENYLAMIDE COMPOUND Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/14—Nitrogen atoms
- C07D261/16—Benzene-sulfonamido isoxazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8619432 | 1986-08-08 | ||
| GB868619432A GB8619432D0 (en) | 1986-08-08 | 1986-08-08 | Pharmaceutical compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK413987D0 DK413987D0 (da) | 1987-08-07 |
| DK413987A true DK413987A (da) | 1988-02-09 |
| DK169404B1 DK169404B1 (da) | 1994-10-24 |
Family
ID=10602473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK413987A DK169404B1 (da) | 1986-08-08 | 1987-08-07 | Substitueret phenylamidforbindelse, fremgangsmåde til fremstilling deraf, anvendelse deraf til brug som farmaceutisk middel og farmaceutisk præparat indeholdende forbindelsen |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4892963A (da) |
| EP (1) | EP0257882B1 (da) |
| JP (1) | JPS63239259A (da) |
| KR (2) | KR880002815A (da) |
| CN (1) | CN1015256B (da) |
| AR (2) | AR244660A1 (da) |
| AT (1) | ATE65494T1 (da) |
| AU (1) | AU604737B2 (da) |
| CA (1) | CA1317964C (da) |
| DE (1) | DE3771611D1 (da) |
| DK (1) | DK169404B1 (da) |
| EG (1) | EG18269A (da) |
| ES (1) | ES2031510T3 (da) |
| GB (1) | GB8619432D0 (da) |
| GR (1) | GR3002714T3 (da) |
| HU (1) | HU197559B (da) |
| IL (1) | IL83432A (da) |
| MX (1) | MX174371B (da) |
| NZ (1) | NZ221352A (da) |
| PH (1) | PH22821A (da) |
| PT (1) | PT85476B (da) |
| RU (1) | RU1771472C (da) |
| ZA (1) | ZA875813B (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5268382A (en) * | 1985-09-27 | 1993-12-07 | Hoechst Aktiengesellschaft | Medicaments to combat autoimmune diseases, in particular systemic lupus erythematosus |
| DE3534440A1 (de) * | 1985-09-27 | 1987-04-02 | Hoechst Ag | Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes |
| US4975462A (en) * | 1988-07-29 | 1990-12-04 | Bristol-Myers Company | Antiarthritic α-arylcarbamoyl cyanoacetic acid derivatives |
| DD297328A5 (de) * | 1989-08-18 | 1992-01-09 | �������@���������k���Kk�� | 5-methyl-isoxalol-4-carbonsaeureanilide und 2 hydroxyethyliden-cyanoessigsaeureanilide zur behandlung von augenerkrankungen |
| US5583150A (en) * | 1989-08-18 | 1996-12-10 | Alcon Laboratories, Inc. | 5-methyl-isoxazole-4-carboxylic acid anilides and 2-hydroxyethylidene-cyano acetic anilides for the treatment of ocular diseases |
| US5108999A (en) * | 1990-02-02 | 1992-04-28 | Syntex (U.S.A.) Inc. | 4-isoxazolecarboxamide derivatives |
| US5001124A (en) * | 1990-02-02 | 1991-03-19 | Syntex (U.S.A.) Inc. | 4-isoxazolecarboxamide derivatives |
| JPH04211048A (ja) * | 1990-03-05 | 1992-08-03 | Mitsubishi Kasei Corp | チオカルバモイルアセトニトリル誘導体 |
| DE59010701D1 (de) * | 1990-05-18 | 1997-05-22 | Hoechst Ag | Isoxazol-4-carbonsäureamide und hydroxyalkyliden-cyanessigsäureamide, diese verbindungen enthaltende arzneimittel und deren verwendung |
| IL102790A (en) * | 1991-09-17 | 1996-01-31 | Roussel Uclaf | 3-Cycloalkyl-prop-2- enamide derivatives |
| EP0538783B1 (de) * | 1991-10-23 | 1995-09-27 | Hoechst Aktiengesellschaft | N-phenyl-2-cyano-3-hydroxycrotonsäureamidderivate und deren Verwendung als Arzneimittel mit immunmodulatorischer Eigenschaft |
| GB9200275D0 (en) * | 1992-01-08 | 1992-02-26 | Roussel Lab Ltd | Chemical compounds |
| TW314467B (da) * | 1993-03-31 | 1997-09-01 | Hoechst Ag | |
| WO1994024095A1 (en) * | 1993-04-16 | 1994-10-27 | Abbott Laboratories | Immunosuppressive agents |
| GB9320299D0 (en) * | 1993-10-01 | 1993-11-17 | Roussel Lab Ltd | Isoxazole derivatives |
| KR100365064B1 (ko) * | 1994-10-17 | 2003-04-11 | 훽스트파마슈티칼스앤드케미칼스가부시키가이샤 | I형알레르기성질환의예방및치료제 |
| DE19702988A1 (de) * | 1997-01-28 | 1998-07-30 | Hoechst Ag | Isoxazol- und Crotonsäureamidderivate und deren Verwendung als Arzneimittel und Diagnostika |
| CN1411373A (zh) * | 1999-12-16 | 2003-04-16 | 特瓦制药工业有限公司 | 制备来氟米特的新方法和新晶形的来氟米特 |
| CA2400290A1 (en) * | 2000-02-15 | 2001-08-23 | Teva Pharmaceutical Industries Ltd. | A method for synthesizing leflunomide |
| DE10311763A1 (de) * | 2003-03-18 | 2004-10-07 | Aventis Pharma Deutschland Gmbh | Verfahren zur Herstellung von 2-Cyan-3-hydroxy-N-(phenyl)but-2-enamiden |
| US6894184B2 (en) | 2003-03-18 | 2005-05-17 | Aventis Pharma Deutschland Gmbh | Process for preparing 2-cyano-3-hydroxy-N-(phenyl)but-2-enamides |
| EP3071199A2 (en) | 2013-11-22 | 2016-09-28 | Genzyme Corporation | Novel methods for treating neurodegenerative diseases |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL186239B (nl) * | 1975-06-05 | Hoechst Ag | Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze. | |
| DK545976A (da) * | 1975-12-11 | 1977-06-12 | Hoechst Ag | Cyaneddikesyreanilidderivater fremgangsmade til deres fremstilling og midler der indeholder disse forbindelser |
| DE2654797A1 (de) * | 1976-12-03 | 1978-06-08 | Hoechst Ag | Verfahren zur herstellung von isoxazolderivaten |
| DE2655009A1 (de) * | 1976-12-04 | 1978-06-15 | Hoechst Ag | Isoxazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel |
| ATE14724T1 (de) * | 1979-06-11 | 1985-08-15 | Ciba Geigy Ag | Alphacarbamoyl-pyrrolpropionitrile, verfahren zu ihrer herstellung, sowie pharmazeutische praeparate die diese verbindungen enthalten. |
-
1986
- 1986-08-08 GB GB868619432A patent/GB8619432D0/en active Pending
-
1987
- 1987-08-02 EG EG448/87A patent/EG18269A/xx active
- 1987-08-03 PH PH35615A patent/PH22821A/en unknown
- 1987-08-04 PT PT85476A patent/PT85476B/pt not_active IP Right Cessation
- 1987-08-04 IL IL83432A patent/IL83432A/xx not_active IP Right Cessation
- 1987-08-05 CA CA000543739A patent/CA1317964C/en not_active Expired - Fee Related
- 1987-08-05 NZ NZ221352A patent/NZ221352A/xx unknown
- 1987-08-06 AT AT87306988T patent/ATE65494T1/de active
- 1987-08-06 DE DE8787306988T patent/DE3771611D1/de not_active Expired - Fee Related
- 1987-08-06 RU SU874203189A patent/RU1771472C/ru active
- 1987-08-06 ZA ZA875813A patent/ZA875813B/xx unknown
- 1987-08-06 EP EP87306988A patent/EP0257882B1/en not_active Expired - Lifetime
- 1987-08-06 ES ES198787306988T patent/ES2031510T3/es not_active Expired - Lifetime
- 1987-08-06 MX MX007668A patent/MX174371B/es unknown
- 1987-08-07 JP JP62198006A patent/JPS63239259A/ja active Pending
- 1987-08-07 US US07/083,538 patent/US4892963A/en not_active Expired - Fee Related
- 1987-08-07 AU AU76681/87A patent/AU604737B2/en not_active Ceased
- 1987-08-07 KR KR1019870008650A patent/KR880002815A/ko not_active Ceased
- 1987-08-07 AR AR87308368A patent/AR244660A1/es active
- 1987-08-07 CN CN87105516A patent/CN1015256B/zh not_active Expired
- 1987-08-07 DK DK413987A patent/DK169404B1/da not_active IP Right Cessation
- 1987-08-07 HU HU873604A patent/HU197559B/hu not_active IP Right Cessation
- 1987-08-07 KR KR1019870008651A patent/KR880002823A/ko not_active Ceased
-
1991
- 1991-09-12 GR GR91401318T patent/GR3002714T3/el unknown
-
1992
- 1992-11-20 AR AR92323708A patent/AR247876A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| CN1015256B (zh) | 1992-01-01 |
| PT85476B (pt) | 1990-06-29 |
| GR3002714T3 (en) | 1993-01-25 |
| AR244660A1 (es) | 1993-11-30 |
| DK169404B1 (da) | 1994-10-24 |
| GB8619432D0 (en) | 1986-09-17 |
| ES2031510T3 (es) | 1992-12-16 |
| ZA875813B (en) | 1989-04-26 |
| AU604737B2 (en) | 1991-01-03 |
| MX7668A (es) | 1993-08-01 |
| ATE65494T1 (de) | 1991-08-15 |
| HU197559B (en) | 1989-04-28 |
| AU7668187A (en) | 1988-02-11 |
| HUT44523A (en) | 1988-03-28 |
| CA1317964C (en) | 1993-05-18 |
| KR880002815A (ko) | 1988-05-11 |
| PT85476A (en) | 1987-09-01 |
| EG18269A (en) | 1992-12-30 |
| JPS63239259A (ja) | 1988-10-05 |
| DE3771611D1 (de) | 1991-08-29 |
| US4892963A (en) | 1990-01-09 |
| AR247876A1 (es) | 1995-04-28 |
| NZ221352A (en) | 1989-10-27 |
| IL83432A0 (en) | 1988-01-31 |
| KR880002823A (ko) | 1988-05-11 |
| IL83432A (en) | 1992-06-21 |
| MX174371B (es) | 1994-05-11 |
| CN87105516A (zh) | 1988-02-24 |
| EP0257882B1 (en) | 1991-07-24 |
| RU1771472C (ru) | 1992-10-23 |
| EP0257882A1 (en) | 1988-03-02 |
| DK413987D0 (da) | 1987-08-07 |
| PH22821A (en) | 1989-01-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |