PH22213A - Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use - Google Patents
Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical useInfo
- Publication number
- PH22213A PH22213A PH33830A PH33830A PH22213A PH 22213 A PH22213 A PH 22213A PH 33830 A PH33830 A PH 33830A PH 33830 A PH33830 A PH 33830A PH 22213 A PH22213 A PH 22213A
- Authority
- PH
- Philippines
- Prior art keywords
- imidazolidines
- spiro
- reductase inhibitors
- pharmaceutical use
- aldose reductase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/738,924 US4575507A (en) | 1985-05-29 | 1985-05-29 | Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use |
Publications (1)
Publication Number | Publication Date |
---|---|
PH22213A true PH22213A (en) | 1988-06-28 |
Family
ID=24970055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH33830A PH22213A (en) | 1985-05-29 | 1986-05-29 | Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use |
Country Status (21)
Country | Link |
---|---|
US (1) | US4575507A (pt) |
EP (1) | EP0203791B1 (pt) |
JP (1) | JPS61277671A (pt) |
KR (1) | KR890001548B1 (pt) |
AT (1) | ATE46332T1 (pt) |
AU (1) | AU560429B2 (pt) |
DD (5) | DD264214A5 (pt) |
DE (1) | DE3665584D1 (pt) |
DK (1) | DK248886A (pt) |
EG (1) | EG17859A (pt) |
ES (2) | ES8800228A1 (pt) |
FI (1) | FI862251A (pt) |
GR (1) | GR861388B (pt) |
HU (4) | HU196060B (pt) |
IL (1) | IL78954A (pt) |
NO (1) | NO862123L (pt) |
NZ (1) | NZ216334A (pt) |
PH (1) | PH22213A (pt) |
PL (5) | PL147398B1 (pt) |
PT (1) | PT82650B (pt) |
ZA (1) | ZA863934B (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU198212B (en) * | 1984-07-20 | 1989-08-28 | Pfizer | Process for production of spiro-imidasolones |
US4762839A (en) * | 1985-06-06 | 1988-08-09 | Tanabe Seiyaku Co., Ltd. | Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications |
JPS63132889A (ja) * | 1986-11-21 | 1988-06-04 | Tanabe Seiyaku Co Ltd | キナゾリノン誘導体 |
AU598366B2 (en) * | 1987-03-20 | 1990-06-21 | Alcon Laboratories, Inc. | Use of aldose reductase inhibitors to enhance insulin sensitivity in diabetes |
US5202339A (en) * | 1987-08-28 | 1993-04-13 | Mochida Pharmaceutical Co., Ltd. | Hydantoin derivatives |
US5004751A (en) * | 1987-08-28 | 1991-04-02 | Mochida Pharmaceutical Co., Ltd. | Hydantoin derivatives |
WO1990002126A1 (en) * | 1988-08-24 | 1990-03-08 | Mochida Pharmaceutical Co., Ltd. | Hydantoin derivatives |
US5068332A (en) * | 1990-10-12 | 1991-11-26 | American Home Products Corporation | Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors |
US8326636B2 (en) * | 2008-01-16 | 2012-12-04 | Canyon Ip Holdings Llc | Using a physical phenomenon detector to control operation of a speech recognition engine |
WO2013117568A1 (de) * | 2012-02-09 | 2013-08-15 | Boehringer Ingelheim International Gmbh | Verfahren zur stereoselektiven synthese von 1,4-geschützten 9-hydroxy-5-oxo-1,4-diaza-spiro [5.5] undecane |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1088945A (en) * | 1976-10-18 | 1980-11-04 | Pfizer Limited | Hydantoin derivatives as therapeutic agents |
US4117230A (en) | 1976-10-18 | 1978-09-26 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
US4235911A (en) * | 1979-06-13 | 1980-11-25 | Pfizer Inc. | Hydantoin derivatives |
US4248882A (en) * | 1980-02-12 | 1981-02-03 | Pfizer Inc. | Treating diabetes-associated complications with hydantoin amines |
JPS5745185A (en) * | 1980-07-21 | 1982-03-13 | Eisai Co Ltd | Hydantoin derivative and its preparation |
EP0109231B1 (en) * | 1982-11-10 | 1986-10-22 | Pfizer Inc. | Sorbinil by optical resolution with aminopinane derivatives |
SU1380610A3 (ru) * | 1982-12-06 | 1988-03-07 | Пфайзер Инк. (Фирма) | Способ получени спирогетероазолидиндионов или их фармацевтически приемлемых солей |
US4556670A (en) | 1982-12-06 | 1985-12-03 | Pfizer Inc. | Spiro-3-hetero-azolones for treatment of diabetic complications |
DE3561198D1 (en) * | 1984-03-23 | 1988-01-28 | Pfizer | Spiro-indenes and spiro-1,2-dihydro-naphthalenes for treatment of diabetic complications |
US4762838A (en) | 1985-08-30 | 1988-08-09 | Pfizer Inc. | Quinazolin-4(3H)-one derivatives as anticoccidial agents |
-
1985
- 1985-05-29 US US06/738,924 patent/US4575507A/en not_active Expired - Lifetime
-
1986
- 1986-05-23 DE DE8686303925T patent/DE3665584D1/de not_active Expired
- 1986-05-23 EP EP86303925A patent/EP0203791B1/en not_active Expired
- 1986-05-23 AT AT86303925T patent/ATE46332T1/de not_active IP Right Cessation
- 1986-05-27 PL PL1986266364A patent/PL147398B1/pl unknown
- 1986-05-27 PL PL1986259739A patent/PL146020B1/pl unknown
- 1986-05-27 DD DD86309079A patent/DD264214A5/de not_active IP Right Cessation
- 1986-05-27 ZA ZA863934A patent/ZA863934B/xx unknown
- 1986-05-27 PL PL1986266363A patent/PL147397B1/pl unknown
- 1986-05-27 PT PT82650A patent/PT82650B/pt not_active IP Right Cessation
- 1986-05-27 DD DD86309080A patent/DD264215A5/de not_active IP Right Cessation
- 1986-05-27 ES ES555375A patent/ES8800228A1/es not_active Expired
- 1986-05-27 PL PL1986266366A patent/PL147400B1/pl unknown
- 1986-05-27 DD DD86290626A patent/DD251972A5/de not_active IP Right Cessation
- 1986-05-27 PL PL1986266365A patent/PL147399B1/pl unknown
- 1986-05-27 DD DD86309078A patent/DD264213A5/de not_active IP Right Cessation
- 1986-05-28 DK DK248886A patent/DK248886A/da not_active Application Discontinuation
- 1986-05-28 AU AU58012/86A patent/AU560429B2/en not_active Ceased
- 1986-05-28 NZ NZ216334A patent/NZ216334A/xx unknown
- 1986-05-28 KR KR8604182A patent/KR890001548B1/ko not_active IP Right Cessation
- 1986-05-28 GR GR861388A patent/GR861388B/el unknown
- 1986-05-28 FI FI862251A patent/FI862251A/fi not_active Application Discontinuation
- 1986-05-28 HU HU862249A patent/HU196060B/hu unknown
- 1986-05-28 HU HU872418A patent/HUT49879A/hu unknown
- 1986-05-28 NO NO862123A patent/NO862123L/no unknown
- 1986-05-28 EG EG317/86A patent/EG17859A/xx active
- 1986-05-28 IL IL78954A patent/IL78954A/xx unknown
- 1986-05-28 HU HU893124A patent/HU199845B/hu unknown
- 1986-05-29 PH PH33830A patent/PH22213A/en unknown
- 1986-05-29 JP JP61124608A patent/JPS61277671A/ja active Pending
-
1987
- 1987-02-13 ES ES557391A patent/ES8801830A1/es not_active Expired
- 1987-05-28 HU HU893127A patent/HU893127D0/hu unknown
- 1987-11-16 DD DD87309077A patent/DD273258A5/de not_active IP Right Cessation
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