PH21177A - 1,6-naphthyridine derivatives, pharmaceutical compositions containing them and method of use - Google Patents

1,6-naphthyridine derivatives, pharmaceutical compositions containing them and method of use

Info

Publication number
PH21177A
PH21177A PH32684A PH32684A PH21177A PH 21177 A PH21177 A PH 21177A PH 32684 A PH32684 A PH 32684A PH 32684 A PH32684 A PH 32684A PH 21177 A PH21177 A PH 21177A
Authority
PH
Philippines
Prior art keywords
chained
straight
carbon atoms
branched alkyl
alkyl radical
Prior art date
Application number
PH32684A
Other languages
English (en)
Inventor
Satzinger Dr Herhard
Kleinschroth Dr Juergen
Weinheimer Dr Gunter
Hartenstein Dr Johannes
Mannhardt Dr Karl
Fritschi Dr Edgar
Osswald Dr Hartmut
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19843431303 external-priority patent/DE3431303A1/de
Priority claimed from DE19853502790 external-priority patent/DE3502790A1/de
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of PH21177A publication Critical patent/PH21177A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Liquid Crystal Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PH32684A 1984-08-25 1985-08-23 1,6-naphthyridine derivatives, pharmaceutical compositions containing them and method of use PH21177A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843431303 DE3431303A1 (de) 1984-08-25 1984-08-25 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
DE19853502790 DE3502790A1 (de) 1985-01-29 1985-01-29 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung

Publications (1)

Publication Number Publication Date
PH21177A true PH21177A (en) 1987-08-07

Family

ID=25824189

Family Applications (4)

Application Number Title Priority Date Filing Date
PH32684A PH21177A (en) 1984-08-25 1985-08-23 1,6-naphthyridine derivatives, pharmaceutical compositions containing them and method of use
PH34327A PH23411A (en) 1984-08-25 1986-10-03 1,6-naphthyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them
PH34326A PH23379A (en) 1984-08-25 1986-10-03 A process for the preparation of 1,6-naphthyridine derivatives
PH35419A PH24762A (en) 1984-08-25 1987-06-17 1,6-naphthyridine derivatives, pharmaceutical compositions and method of use

Family Applications After (3)

Application Number Title Priority Date Filing Date
PH34327A PH23411A (en) 1984-08-25 1986-10-03 1,6-naphthyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them
PH34326A PH23379A (en) 1984-08-25 1986-10-03 A process for the preparation of 1,6-naphthyridine derivatives
PH35419A PH24762A (en) 1984-08-25 1987-06-17 1,6-naphthyridine derivatives, pharmaceutical compositions and method of use

Country Status (22)

Country Link
US (1) US4711901A (fr)
EP (1) EP0173933B1 (fr)
KR (1) KR890000706B1 (fr)
AT (1) ATE48276T1 (fr)
AU (1) AU576887B2 (fr)
BG (1) BG43691A3 (fr)
CA (1) CA1263118A (fr)
DE (1) DE3574471D1 (fr)
DK (1) DK165247C (fr)
ES (1) ES8604960A1 (fr)
FI (1) FI80697C (fr)
GR (1) GR852040B (fr)
HU (1) HU194879B (fr)
IE (1) IE58364B1 (fr)
IL (2) IL75987A (fr)
NO (1) NO161493C (fr)
NZ (1) NZ213218A (fr)
PH (4) PH21177A (fr)
PL (1) PL146668B1 (fr)
RO (1) RO92245B (fr)
SU (1) SU1395143A3 (fr)
YU (2) YU45000B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3431303A1 (de) * 1984-08-25 1986-02-27 Goedecke Ag 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
DE3906460C1 (fr) * 1989-03-01 1990-11-15 Goedecke Ag, 1000 Berlin, De
DE3906406C1 (fr) * 1989-03-01 1990-10-25 Goedecke Ag, 1000 Berlin, De
DE102006026583A1 (de) 2006-06-07 2007-12-13 Bayer Healthcare Aktiengesellschaft Aryl-substituierte hetero-bicyclische Verbindungen und ihre Verwendung
DE102006026585A1 (de) 2006-06-07 2007-12-13 Bayer Healthcare Aktiengesellschaft Substituierte 4-Aryl-1,4-dihydro-1,6-naphthyridine und ihre Verwendung
DE102007009494A1 (de) 2007-02-27 2008-08-28 Bayer Healthcare Ag Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung
AU2015295376C1 (en) * 2014-08-01 2020-07-16 Bayer Pharma Aktiengesellschaft Method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carbox-amide and the purification thereof for use as an active pharmaceutical ingredient
CN107849043B (zh) * 2015-08-21 2020-10-16 拜耳制药股份公司 用于制备(4s)-4-(4-氰基-2-甲氧基苯基)-5-乙氧基-2,8-二甲基-1,4-二氢-1,6-萘啶-3-甲酰胺的方法
PE20180555A1 (es) * 2015-08-21 2018-04-02 Bayer Pharma AG Procedimiento para la preparacion de (4s)-4-(4-ciano-2-metoxifenilo)-5-etoxi-2,8-dimetil-1,4-dihidro-1,6-naftiridina-3-carboxamida y para la recuperacion de (4s)-4-(4-ciano-2-metoxifenilo)-5-etoxi-2,8-dimetil-1,4-dihidro-1,6-naftiridina-3-carboxamida por medio de metodos electroquimicos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304914A (en) * 1980-07-07 1981-12-08 Usv Pharmaceutical Corporation Naphthyridone derivatives
DE3327650A1 (de) * 1983-07-30 1985-02-14 Gödecke AG, 1000 Berlin 1,6-naphthyridinon-derivate, verfahren zu deren herstellung und deren verwendung bei der bekaempfung von gefaesserkrankungen

Also Published As

Publication number Publication date
YU14588A (en) 1991-02-28
NO161493B (no) 1989-05-16
YU134885A (en) 1988-10-31
ES8604960A1 (es) 1986-03-01
IL75987A (en) 1991-07-18
IL75987A0 (en) 1985-12-31
SU1395143A3 (ru) 1988-05-07
YU47010B (sh) 1994-11-15
IE852085L (en) 1986-02-25
EP0173933B1 (fr) 1989-11-29
RO92245B (ro) 1987-07-31
GR852040B (fr) 1985-12-19
PH24762A (en) 1990-10-01
CA1263118A (fr) 1989-11-21
ATE48276T1 (de) 1989-12-15
KR890000706B1 (ko) 1989-03-27
DE3574471D1 (de) 1990-01-04
PH23411A (en) 1989-07-26
DK384485A (da) 1986-02-26
RO92245A (fr) 1987-07-30
IE58364B1 (en) 1993-09-08
BG43691A3 (en) 1988-07-15
KR860001810A (ko) 1986-03-22
US4711901A (en) 1987-12-08
PH23379A (en) 1989-07-26
DK384485D0 (da) 1985-08-23
DK165247B (da) 1992-10-26
DK165247C (da) 1993-04-26
NO853329L (no) 1986-02-26
FI80697B (fi) 1990-03-30
FI853233L (fi) 1986-02-26
FI853233A0 (fi) 1985-08-22
AU4662685A (en) 1986-02-27
EP0173933A1 (fr) 1986-03-12
HUT39448A (en) 1986-09-29
NZ213218A (en) 1990-01-29
PL255118A1 (en) 1986-07-29
HU194879B (en) 1988-03-28
FI80697C (fi) 1990-07-10
YU45000B (en) 1991-06-30
AU576887B2 (en) 1988-09-08
NO161493C (no) 1989-08-23
ES546366A0 (es) 1986-03-01
PL146668B1 (en) 1989-02-28

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