PH14127A - 2-tetrahydrofurfuryl-5-lower alkyl-2'oxy-6,7-benzomorphans,salts thereof and compositions containing them - Google Patents

2-tetrahydrofurfuryl-5-lower alkyl-2'oxy-6,7-benzomorphans,salts thereof and compositions containing them

Info

Publication number
PH14127A
PH14127A PH16895A PH16895A PH14127A PH 14127 A PH14127 A PH 14127A PH 16895 A PH16895 A PH 16895A PH 16895 A PH16895 A PH 16895A PH 14127 A PH14127 A PH 14127A
Authority
PH
Philippines
Prior art keywords
benzomorphans
tetrahydrofurfuryl
oxy
salts
lower alkyl
Prior art date
Application number
PH16895A
Other languages
English (en)
Inventor
K Stockhaus
A Langbein
H Merz
G Walther
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of PH14127A publication Critical patent/PH14127A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PH16895A 1974-03-09 1975-03-10 2-tetrahydrofurfuryl-5-lower alkyl-2'oxy-6,7-benzomorphans,salts thereof and compositions containing them PH14127A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
PH14127A true PH14127A (en) 1981-02-26

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
PH16895A PH14127A (en) 1974-03-09 1975-03-10 2-tetrahydrofurfuryl-5-lower alkyl-2'oxy-6,7-benzomorphans,salts thereof and compositions containing them

Country Status (25)

Country Link
JP (1) JPS5827275B2 (nl)
AT (1) AT344332B (nl)
BE (1) BE826440A (nl)
BG (3) BG24814A4 (nl)
CA (1) CA1049511A (nl)
CH (8) CH612425A5 (nl)
CS (1) CS188221B2 (nl)
DD (1) DD119236A5 (nl)
DE (1) DE2411382C3 (nl)
DK (1) DK137188C (nl)
ES (6) ES440348A1 (nl)
FI (1) FI63571C (nl)
FR (1) FR2262984B1 (nl)
GB (1) GB1496418A (nl)
HU (1) HU177408B (nl)
IE (1) IE40945B1 (nl)
IL (1) IL46760A (nl)
NL (1) NL7502724A (nl)
NO (1) NO141800C (nl)
PH (1) PH14127A (nl)
PL (3) PL93700B1 (nl)
RO (2) RO69617A (nl)
SE (1) SE421919B (nl)
SU (3) SU577982A3 (nl)
ZA (1) ZA751394B (nl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
CZ291132B6 (cs) * 1995-03-10 2002-12-11 Photocure Asa Estery kyselin 5-aminolevulových a farmaceutický prostředek s jejich obsahem
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
ES2395081T3 (es) 2007-07-26 2013-02-08 Vitae Pharmaceuticals, Inc. Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1
TW200927115A (en) 2007-11-16 2009-07-01 Boehringer Ingelheim Int Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
EP2229368A1 (en) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
CA2715290A1 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134392A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5301563B2 (ja) 2008-05-01 2013-09-25 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2324018B1 (en) 2008-07-25 2013-09-04 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
IL46760A (en) 1978-12-17
SU577983A3 (ru) 1977-10-25
SE7502592L (nl) 1975-09-10
JPS50123675A (nl) 1975-09-29
PL93700B1 (nl) 1977-06-30
JPS5827275B2 (ja) 1983-06-08
RO70051A (ro) 1980-12-30
ZA751394B (en) 1976-11-24
DE2411382B2 (de) 1979-01-18
FI63571B (fi) 1983-03-31
IE40945B1 (en) 1979-09-12
CH620439A5 (en) 1980-11-28
FR2262984B1 (nl) 1978-07-28
DE2411382C3 (de) 1979-09-06
FR2262984A1 (nl) 1975-10-03
PL93499B1 (nl) 1977-05-30
BG24813A4 (en) 1978-05-12
IL46760A0 (en) 1975-05-22
CH620440A5 (en) 1980-11-28
ATA153875A (de) 1977-11-15
CH622016A5 (en) 1981-03-13
IE40945L (en) 1975-09-09
FI63571C (fi) 1983-07-11
FI750652A (nl) 1975-09-10
ES440350A1 (es) 1977-03-16
CH622015A5 (en) 1981-03-13
DK137188B (da) 1978-01-30
NL7502724A (nl) 1975-09-11
CH622017A5 (en) 1981-03-13
SU588916A3 (ru) 1978-01-15
BG24814A4 (en) 1978-05-12
ES440349A1 (es) 1977-03-01
ES440347A1 (es) 1977-06-01
BE826440A (fr) 1975-09-08
CH620681A5 (en) 1980-12-15
BG25087A3 (en) 1978-07-12
DE2411382A1 (de) 1975-09-18
RO69617A (ro) 1980-08-15
HU177408B (en) 1981-10-28
NO141800B (no) 1980-02-04
DK137188C (da) 1978-07-03
ES440346A1 (es) 1977-03-01
SU577982A3 (ru) 1977-10-25
AT344332B (de) 1978-07-10
PL93699B1 (nl) 1977-06-30
NO750773L (nl) 1975-09-10
CH612425A5 (en) 1979-07-31
ES440345A1 (es) 1977-03-01
DK92975A (nl) 1975-09-10
NO141800C (no) 1980-06-04
SE421919B (sv) 1982-02-08
GB1496418A (en) 1977-12-30
CH622014A5 (en) 1981-03-13
AU7894275A (en) 1976-09-16
ES440348A1 (es) 1977-06-01
CS188221B2 (en) 1979-02-28
CA1049511A (en) 1979-02-27
DD119236A5 (nl) 1976-04-12

Similar Documents

Publication Publication Date Title
PH14127A (en) 2-tetrahydrofurfuryl-5-lower alkyl-2'oxy-6,7-benzomorphans,salts thereof and compositions containing them
IL48704A0 (en) Azolyl-(1)-methanes and their salts,their preparation and pharmaceutical compositions containing them
IL47860A0 (en) Novel 5,9 beta-disubstituted 2-tetrahydrofuryl-6,7-benzomorphans and their salts,their production and pharmaceutical compositions containing them
ZA755614B (en) 1,3,4-trisubstituted-4-arylpiperidines and their preparation
NZ185965A (en) 5'-deoxy-5-fluor ocytidine, 5'-deoxy-5-fluoro-uridine and pharmaceutical compositions
IL46959A0 (en) 1,1-diaryl-1-oxadiazolyl-alkylamines,their preparation and pharmaceutical compositions containing them
PH15360A (en) 6-phenyl-4h-s-triazilo-3,4,c-thieno-2,3,e-1,4-diazephine and salt thereof
IL51309A0 (en) New 1,2-benzisothiazolin-3-ones,their preparation and pharmaceutical compositions containing them
IL47413A0 (en) New 1,4-dihydropyridines,their manufacture and pharmaceutical compositions containing them
IL47929A (en) Phenylnona-2,4,6,8-tetraenoic acid -8,6,4,2-derivatives,their manufacture and pharmaceutical compositions containing them
IL48214A (en) 2-(2,6-disubstituted-phenyl)imino)-imidazolidines,their preparation and antihypertensive compositions containing them
IL52615A0 (en) Novel 1,5-disubstituted-2-pyrrolidones,their production and pharmaceutical compositions containing them
IL48572A0 (en) 8,8-disubstituted-6-methylergolines and related compounds
IL47878A (en) S-substituted 4,5-diphenyloxazole-2-thiol derivatives,their preparation and compositions containing them
IL49132A (en) 16,1l-disubstituted androst-4-en-3-ones,their preparation and pharmaceutical compositions containing them
NZ185539A (en) Cis-4a-aryl-2-substituted-2,3,4,4a,5,6,7,7a-octa hydro-1h-2-pyrindines and pharmaceutical compositions
NZ184185A (en) 3,5,5-trimethylhexanoyl-ferrocene and pharmaceutical compositions
IL47501A (en) 1-imidazolyl-(1-(4'-(4''-chlorophenyl)-phenoxy-3,3-dimethyl-butan2-one and its salts, their preparation and pharmacetical compositions containing them
IL46476A0 (en) 2-substituted 4,5-diphenylthiazoles,their preparation and pharmaceutical compositions containing them
IL46409A (en) 7,8-dihalo-1,2,3,4-tetrahydro-isoquinolines their preparation and pharmaceutical compositions containing them
IL48527A0 (en) New 7,7-diphenyl-hexahydro-1,4-oxazepines,their manufacture and pharmaceutical compositions containing them
IL51373A (en) Pharmaceutical compositions containing halocinnamides,certain such compounds and their preparation
NZ185996A (en) 6, 7-methylene-3-oxo-d-homo-17a-pregna-4, 16-dienes and pharmaceutical compositions
ZA754921B (en) 1-aryl-2-oxo-hexahydro-2,4,5,6,7,7a-indoles and acid addition salts thereof
IL48140A0 (en) Novel 2,6-methano-3-benzazocines and their preparation