PH12019500461B1 - Fused bicyclic sgc stimulators - Google Patents

Fused bicyclic sgc stimulators

Info

Publication number
PH12019500461B1
PH12019500461B1 PH1/2019/500461A PH12019500461A PH12019500461B1 PH 12019500461 B1 PH12019500461 B1 PH 12019500461B1 PH 12019500461 A PH12019500461 A PH 12019500461A PH 12019500461 B1 PH12019500461 B1 PH 12019500461B1
Authority
PH
Philippines
Prior art keywords
fused bicyclic
sgc stimulators
concentration
increase
sgc
Prior art date
Application number
PH1/2019/500461A
Other languages
English (en)
Other versions
PH12019500461A1 (en
Inventor
Timothy Claude Barden
Peter Germano
G-Yoon Jamie Im
Rajesh R Iyengar
Karthik Iyer
Lei Jia
Joon Jung
Thomas Wai-Ho Lee
Ara Mermerian
Takashi Nakai
Paul Allan Renhowe
Glen Robert Rennie
Kim Tang
Original Assignee
Tisento Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tisento Therapeutics Inc filed Critical Tisento Therapeutics Inc
Publication of PH12019500461A1 publication Critical patent/PH12019500461A1/en
Publication of PH12019500461B1 publication Critical patent/PH12019500461B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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PH1/2019/500461A 2016-09-02 2017-09-01 Fused bicyclic sgc stimulators PH12019500461B1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662382942P 2016-09-02 2016-09-02
US201662423445P 2016-11-17 2016-11-17
US201762468598P 2017-03-08 2017-03-08
US201762482486P 2017-04-06 2017-04-06
PCT/US2017/049834 WO2018045276A1 (en) 2016-09-02 2017-09-01 Fused bicyclic sgc stimulators

Publications (2)

Publication Number Publication Date
PH12019500461A1 PH12019500461A1 (en) 2019-06-03
PH12019500461B1 true PH12019500461B1 (en) 2023-08-09

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Application Number Title Priority Date Filing Date
PH1/2019/500461A PH12019500461B1 (en) 2016-09-02 2017-09-01 Fused bicyclic sgc stimulators

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US (5) US10472363B2 (OSRAM)
EP (2) EP3872080B1 (OSRAM)
JP (2) JP7050759B2 (OSRAM)
KR (2) KR102854313B1 (OSRAM)
CN (2) CN117105939A (OSRAM)
AU (2) AU2017321810B2 (OSRAM)
CA (1) CA3035210A1 (OSRAM)
CL (1) CL2019000486A1 (OSRAM)
CO (1) CO2019001760A2 (OSRAM)
CR (2) CR20220309A (OSRAM)
CY (1) CY1124612T1 (OSRAM)
DK (1) DK3507291T3 (OSRAM)
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