DK3507291T3 - Kondenserede bicykliske sgc-stimulatorer - Google Patents

Kondenserede bicykliske sgc-stimulatorer Download PDF

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Publication number
DK3507291T3
DK3507291T3 DK17768311.7T DK17768311T DK3507291T3 DK 3507291 T3 DK3507291 T3 DK 3507291T3 DK 17768311 T DK17768311 T DK 17768311T DK 3507291 T3 DK3507291 T3 DK 3507291T3
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Prior art keywords
condensed bicyclic
sgc stimulators
sgc
stimulators
bicyclic
Prior art date
Application number
DK17768311.7T
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English (en)
Inventor
Glen Robert Rennie
Rajesh R Iyengar
Thomas Wai-Ho Lee
Takashi Nakai
Ara Mermerian
Lei Jia
Paul Allan Renhowe
Joon Jung
Peter Germano
G-Yoon Jamie Im
Timothy Claude Barden
Kim Tang
Karthik Iyer
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Cyclerion Therapeutics Inc
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Application filed by Cyclerion Therapeutics Inc filed Critical Cyclerion Therapeutics Inc
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Publication of DK3507291T3 publication Critical patent/DK3507291T3/da

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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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DK17768311.7T 2016-09-02 2017-09-01 Kondenserede bicykliske sgc-stimulatorer DK3507291T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662382942P 2016-09-02 2016-09-02
US201662423445P 2016-11-17 2016-11-17
US201762468598P 2017-03-08 2017-03-08
US201762482486P 2017-04-06 2017-04-06
PCT/US2017/049834 WO2018045276A1 (en) 2016-09-02 2017-09-01 Fused bicyclic sgc stimulators

Publications (1)

Publication Number Publication Date
DK3507291T3 true DK3507291T3 (da) 2021-08-30

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DK17768311.7T DK3507291T3 (da) 2016-09-02 2017-09-01 Kondenserede bicykliske sgc-stimulatorer

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US (4) US10472363B2 (da)
EP (2) EP3872080B1 (da)
JP (2) JP7050759B2 (da)
KR (2) KR20230124760A (da)
CN (2) CN117105939A (da)
AU (2) AU2017321810B2 (da)
BR (1) BR112019004468A2 (da)
CA (1) CA3035210A1 (da)
CL (1) CL2019000486A1 (da)
CO (1) CO2019001760A2 (da)
CR (2) CR20220309A (da)
CY (1) CY1124612T1 (da)
DK (1) DK3507291T3 (da)
ES (2) ES2957159T3 (da)
HR (1) HRP20211355T1 (da)
HU (1) HUE056051T2 (da)
IL (2) IL292968A (da)
LT (1) LT3507291T (da)
MA (1) MA53999A (da)
MX (3) MX2021007580A (da)
PE (1) PE20190607A1 (da)
PH (1) PH12019500461A1 (da)
PL (1) PL3507291T3 (da)
PT (1) PT3507291T (da)
RS (1) RS62256B1 (da)
SG (1) SG11201901729YA (da)
SI (1) SI3507291T1 (da)
TW (2) TWI750218B (da)
WO (1) WO2018045276A1 (da)

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KR100467946B1 (ko) * 1997-01-24 2005-01-24 로무 가부시키가이샤 반도체 칩의 제조방법
WO2016044446A2 (en) * 2014-09-17 2016-03-24 Ironwood Pharmaceuticals, Inc. Sgc stimulators
CA3015172A1 (en) 2016-02-18 2017-08-24 Privo Technologies, Inc. Two-stage microparticle-based therapeutic delivery system and method
TWI750218B (zh) 2016-09-02 2021-12-21 美商賽克瑞恩醫療公司 sGC 刺激劑
CN110267658B (zh) * 2016-11-08 2024-02-02 帝善多制药公司 用sGC刺激剂治疗CNS疾病
US20180235899A1 (en) 2017-02-17 2018-08-23 Privo Technologies, Inc. Particle-based multi-layer therapeutic delivery device and method
US10478403B1 (en) 2017-05-03 2019-11-19 Privo Technologies, Inc. Intraoperative topically-applied non-implantable rapid release patch
JP7474709B2 (ja) 2018-02-27 2024-04-25 インサイト・コーポレイション Ａ２ａ／ａ２ｂ阻害剤としてのイミダゾピリミジン及びトリアゾロピリミジン
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