PT3507291T - Estimulantes de sgc bicíclicos fundidos - Google Patents

Estimulantes de sgc bicíclicos fundidos

Info

Publication number
PT3507291T
PT3507291T PT177683117T PT17768311T PT3507291T PT 3507291 T PT3507291 T PT 3507291T PT 177683117 T PT177683117 T PT 177683117T PT 17768311 T PT17768311 T PT 17768311T PT 3507291 T PT3507291 T PT 3507291T
Authority
PT
Portugal
Prior art keywords
fused bicyclic
sgc stimulators
sgc
stimulators
bicyclic
Prior art date
Application number
PT177683117T
Other languages
English (en)
Original Assignee
Cyclerion Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyclerion Therapeutics Inc filed Critical Cyclerion Therapeutics Inc
Publication of PT3507291T publication Critical patent/PT3507291T/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
PT177683117T 2016-09-02 2017-09-01 Estimulantes de sgc bicíclicos fundidos PT3507291T (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662382942P 2016-09-02 2016-09-02
US201662423445P 2016-11-17 2016-11-17
US201762468598P 2017-03-08 2017-03-08
US201762482486P 2017-04-06 2017-04-06

Publications (1)

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PT3507291T true PT3507291T (pt) 2021-08-30

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US (4) US10472363B2 (pt)
EP (2) EP3507291B1 (pt)
JP (2) JP7050759B2 (pt)
KR (2) KR102568384B1 (pt)
CN (2) CN117105939A (pt)
AU (2) AU2017321810B2 (pt)
BR (1) BR112019004468A2 (pt)
CA (1) CA3035210A1 (pt)
CL (1) CL2019000486A1 (pt)
CO (1) CO2019001760A2 (pt)
CR (2) CR20220309A (pt)
CY (1) CY1124612T1 (pt)
DK (1) DK3507291T3 (pt)
ES (2) ES2885003T3 (pt)
HR (1) HRP20211355T1 (pt)
HU (1) HUE056051T2 (pt)
IL (2) IL264955B (pt)
LT (1) LT3507291T (pt)
MA (1) MA53999A (pt)
MX (3) MX2021007580A (pt)
PE (1) PE20190607A1 (pt)
PH (1) PH12019500461A1 (pt)
PL (1) PL3507291T3 (pt)
PT (1) PT3507291T (pt)
RS (1) RS62256B1 (pt)
SG (1) SG11201901729YA (pt)
SI (1) SI3507291T1 (pt)
TW (2) TWI813078B (pt)
WO (1) WO2018045276A1 (pt)

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CN110267658B (zh) * 2016-11-08 2024-02-02 帝善多制药公司 用sGC刺激剂治疗CNS疾病
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CA3098475A1 (en) * 2018-04-30 2019-11-07 Bayer Aktiengesellschaft The use of sgc activators and sgc stimulators for the treatment of cognitive impairment
WO2019222677A1 (en) 2018-05-18 2019-11-21 Incyte Corporation Fused pyrimidine derivatives as a2a / a2b inhibitors
AU2019301683A1 (en) * 2018-07-11 2021-02-11 Tisento Therapeutics Inc. Use of sGC stimulators for the treatment of mitochonrial disorders
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