SG11202008592UA - Process for preparing soluble guanylate cyclase stimulators - Google Patents

Process for preparing soluble guanylate cyclase stimulators

Info

Publication number
SG11202008592UA
SG11202008592UA SG11202008592UA SG11202008592UA SG11202008592UA SG 11202008592U A SG11202008592U A SG 11202008592UA SG 11202008592U A SG11202008592U A SG 11202008592UA SG 11202008592U A SG11202008592U A SG 11202008592UA SG 11202008592U A SG11202008592U A SG 11202008592UA
Authority
SG
Singapore
Prior art keywords
guanylate cyclase
soluble guanylate
preparing soluble
cyclase stimulators
stimulators
Prior art date
Application number
SG11202008592UA
Inventor
Thomas Storz
Original Assignee
Cyclerion Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyclerion Therapeutics Inc filed Critical Cyclerion Therapeutics Inc
Publication of SG11202008592UA publication Critical patent/SG11202008592UA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11202008592UA 2018-03-07 2019-03-07 Process for preparing soluble guanylate cyclase stimulators SG11202008592UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862639642P 2018-03-07 2018-03-07
PCT/US2019/021076 WO2019173548A1 (en) 2018-03-07 2019-03-07 Process for preparing soluble guanylate cyclase stimulators

Publications (1)

Publication Number Publication Date
SG11202008592UA true SG11202008592UA (en) 2020-10-29

Family

ID=65904546

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202008592UA SG11202008592UA (en) 2018-03-07 2019-03-07 Process for preparing soluble guanylate cyclase stimulators

Country Status (19)

Country Link
US (2) US11466014B2 (en)
EP (1) EP3762390A1 (en)
JP (1) JP7406692B2 (en)
KR (1) KR20200128707A (en)
CN (1) CN111836811A (en)
AU (1) AU2019231721B2 (en)
BR (1) BR112020017999A2 (en)
CA (1) CA3092680A1 (en)
CL (2) CL2020002283A1 (en)
CO (1) CO2020012492A2 (en)
CR (1) CR20200457A (en)
EA (1) EA202092108A1 (en)
IL (1) IL276852B2 (en)
MX (2) MX2020009185A (en)
PE (1) PE20211413A1 (en)
PH (1) PH12020551389A1 (en)
SG (1) SG11202008592UA (en)
TW (1) TWI812679B (en)
WO (1) WO2019173548A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230130739A1 (en) 2020-03-26 2023-04-27 Cyclerion Therapeutics, Inc. DEUTERATED sGC STIMULATORS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7498350B2 (en) * 2002-11-28 2009-03-03 Astrazeneca Ab Oxazolidinones as antibacterial agents
US9796733B2 (en) 2014-06-04 2017-10-24 Merck Sharp & Dohme Corp. Imidazo-pyrazine derivatives useful as soluble guanylate cyclase activators
EP3194386A2 (en) * 2014-09-17 2017-07-26 Ironwood Pharmaceuticals, Inc. Sgc stimulators
BR112019004468A2 (en) * 2016-09-02 2019-05-28 Ironwood Pharmaceuticals Inc sgc stimulants

Also Published As

Publication number Publication date
TWI812679B (en) 2023-08-21
US11466014B2 (en) 2022-10-11
MX2020009185A (en) 2020-10-08
CN111836811A (en) 2020-10-27
IL276852A (en) 2020-10-29
CR20200457A (en) 2020-11-23
EP3762390A1 (en) 2021-01-13
KR20200128707A (en) 2020-11-16
US20230128639A1 (en) 2023-04-27
IL276852B2 (en) 2024-06-01
WO2019173548A1 (en) 2019-09-12
PE20211413A1 (en) 2021-08-02
IL276852B1 (en) 2024-02-01
CO2020012492A2 (en) 2020-10-30
US20210032254A1 (en) 2021-02-04
TW202000668A (en) 2020-01-01
EA202092108A1 (en) 2021-03-04
JP7406692B2 (en) 2023-12-28
CA3092680A1 (en) 2019-09-12
JP2021515018A (en) 2021-06-17
AU2019231721B2 (en) 2024-06-27
AU2019231721A1 (en) 2020-10-22
BR112020017999A2 (en) 2020-12-22
MX2022015309A (en) 2023-01-11
PH12020551389A1 (en) 2021-09-13
CL2021000302A1 (en) 2021-06-18
CL2020002283A1 (en) 2020-11-27

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