PH12019500287A1 - Crystals of cyclic amine derivative and pharmaceutical use thereof - Google Patents
Crystals of cyclic amine derivative and pharmaceutical use thereofInfo
- Publication number
- PH12019500287A1 PH12019500287A1 PH12019500287A PH12019500287A PH12019500287A1 PH 12019500287 A1 PH12019500287 A1 PH 12019500287A1 PH 12019500287 A PH12019500287 A PH 12019500287A PH 12019500287 A PH12019500287 A PH 12019500287A PH 12019500287 A1 PH12019500287 A1 PH 12019500287A1
- Authority
- PH
- Philippines
- Prior art keywords
- crystals
- amine derivative
- pharmaceutical use
- cyclic amine
- present
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 4
- -1 cyclic amine Chemical class 0.000 title 1
- QUTKDCYSTKFFEU-LBPRGKRZSA-N (3S)-1-[4-(dimethylamino)piperidin-1-yl]-3-hydroxy-3-(1-methylimidazol-2-yl)propan-1-one Chemical compound CN(C1CCN(CC1)C(C[C@@H](C=1N(C=CN=1)C)O)=O)C QUTKDCYSTKFFEU-LBPRGKRZSA-N 0.000 abstract 1
- 208000001640 Fibromyalgia Diseases 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016165437 | 2016-08-26 | ||
| PCT/JP2017/030528 WO2018038255A1 (ja) | 2016-08-26 | 2017-08-25 | 環状アミン誘導体の結晶及びその医薬用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12019500287A1 true PH12019500287A1 (en) | 2019-10-28 |
Family
ID=61244990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH12019500287A PH12019500287A1 (en) | 2016-08-26 | 2019-02-11 | Crystals of cyclic amine derivative and pharmaceutical use thereof |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US10961217B2 (ar) |
| EP (1) | EP3505515B1 (ar) |
| JP (1) | JP6610793B2 (ar) |
| KR (1) | KR102235994B1 (ar) |
| CN (1) | CN109563072B (ar) |
| AU (1) | AU2017314560B2 (ar) |
| CA (1) | CA3035161A1 (ar) |
| DK (1) | DK3505515T3 (ar) |
| ES (1) | ES2905733T3 (ar) |
| HU (1) | HUE057370T2 (ar) |
| IL (1) | IL264673B (ar) |
| MX (1) | MX2019001380A (ar) |
| PH (1) | PH12019500287A1 (ar) |
| PL (1) | PL3505515T3 (ar) |
| PT (1) | PT3505515T (ar) |
| RU (1) | RU2719384C1 (ar) |
| SA (1) | SA519401004B1 (ar) |
| TW (1) | TWI702210B (ar) |
| WO (1) | WO2018038255A1 (ar) |
| ZA (1) | ZA201901263B (ar) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6800492B2 (ja) * | 2018-06-29 | 2020-12-16 | ＭｉＺ株式会社 | 水素を含む癌性疼痛の抑制もしくは軽減のための組成物 |
| CN111039984B (zh) * | 2018-10-15 | 2022-06-07 | 上海盟科药业股份有限公司 | 康泰唑胺酯的药物晶体及其制备方法和应用 |
| JP7447803B2 (ja) * | 2018-12-26 | 2024-03-12 | 東レ株式会社 | アドビリン機能促進剤としての環状アミン誘導体並びに新規環状アミン誘導体及びその医薬用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3524955A1 (de) * | 1984-07-19 | 1986-01-30 | Sandoz-Patent-GmbH, 7850 Lörrach | 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel |
| GB2163150B (en) | 1984-07-19 | 1988-05-25 | Sandoz Ltd | 3-aminopropoxyaryl derivatives |
| JPS6137765A (ja) * | 1984-07-19 | 1986-02-22 | サンド・アクチエンゲゼルシヤフト | ３‐アミノプロポキシアリール誘導体 |
| JP2567885Y2 (ja) | 1991-03-15 | 1998-04-08 | ソニー株式会社 | ビデオモニタ装置 |
| US6627646B2 (en) * | 2001-07-17 | 2003-09-30 | Sepracor Inc. | Norastemizole polymorphs |
| WO2003031432A1 (en) | 2001-10-12 | 2003-04-17 | Novo Nordisk A/S | Substituted piperidines and their use for the treatment of diseases related to the histamine h3 receptor |
| FR2862647B1 (fr) * | 2003-11-25 | 2008-07-04 | Aventis Pharma Sa | Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant |
| JP2006008664A (ja) | 2004-05-21 | 2006-01-12 | Takeda Chem Ind Ltd | イミダゾール誘導体、その製造法及び用途 |
| TW201350119A (zh) * | 2012-03-29 | 2013-12-16 | Toray Industries | 環狀胺衍生物及其醫藥用途 |
| TWI652264B (zh) * | 2013-09-26 | 2019-03-01 | 東麗股份有限公司 | Cyclic amine derivatives and their medical uses |
| EP3263565B1 (en) * | 2015-02-27 | 2019-06-26 | Toray Industries, Inc. | Cyclic amine derivative and pharmaceutical use thereof |
| JP6767011B2 (ja) * | 2015-09-18 | 2020-10-14 | ヤマサ醤油株式会社 | 抗ｄｎａウィルス活性などの生理活性を有するヌクレオシド誘導体 |
-
2017
- 2017-08-25 CN CN201780051578.1A patent/CN109563072B/zh active Active
- 2017-08-25 JP JP2018535784A patent/JP6610793B2/ja active Active
- 2017-08-25 KR KR1020197005849A patent/KR102235994B1/ko active IP Right Grant
- 2017-08-25 US US16/326,580 patent/US10961217B2/en active Active
- 2017-08-25 TW TW106128883A patent/TWI702210B/zh active
- 2017-08-25 ES ES17843731T patent/ES2905733T3/es active Active
- 2017-08-25 CA CA3035161A patent/CA3035161A1/en active Pending
- 2017-08-25 HU HUE17843731A patent/HUE057370T2/hu unknown
- 2017-08-25 DK DK17843731.5T patent/DK3505515T3/da active
- 2017-08-25 WO PCT/JP2017/030528 patent/WO2018038255A1/ja unknown
- 2017-08-25 AU AU2017314560A patent/AU2017314560B2/en active Active
- 2017-08-25 RU RU2019108061A patent/RU2719384C1/ru active
- 2017-08-25 EP EP17843731.5A patent/EP3505515B1/en active Active
- 2017-08-25 PL PL17843731T patent/PL3505515T3/pl unknown
- 2017-08-25 PT PT178437315T patent/PT3505515T/pt unknown
- 2017-08-25 MX MX2019001380A patent/MX2019001380A/es unknown
-
2019
- 2019-01-31 SA SA519401004A patent/SA519401004B1/ar unknown
- 2019-02-05 IL IL26467319A patent/IL264673B/en active IP Right Grant
- 2019-02-11 PH PH12019500287A patent/PH12019500287A1/en unknown
- 2019-02-27 ZA ZA2019/01263A patent/ZA201901263B/en unknown
-
2021
- 2021-02-10 US US17/172,240 patent/US11834431B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017314560A1 (en) | 2019-02-21 |
| EP3505515A4 (en) | 2020-02-12 |
| CA3035161A1 (en) | 2018-03-01 |
| CN109563072B (zh) | 2021-05-11 |
| MX2019001380A (es) | 2019-05-20 |
| JPWO2018038255A1 (ja) | 2019-02-28 |
| ZA201901263B (en) | 2021-06-30 |
| US10961217B2 (en) | 2021-03-30 |
| CN109563072A (zh) | 2019-04-02 |
| WO2018038255A1 (ja) | 2018-03-01 |
| RU2719384C1 (ru) | 2020-04-17 |
| PT3505515T (pt) | 2022-02-11 |
| PL3505515T3 (pl) | 2022-04-04 |
| KR102235994B1 (ko) | 2021-04-05 |
| JP6610793B2 (ja) | 2019-11-27 |
| ES2905733T3 (es) | 2022-04-11 |
| US20200172507A1 (en) | 2020-06-04 |
| AU2017314560B2 (en) | 2021-06-03 |
| KR20190034609A (ko) | 2019-04-02 |
| TW201808932A (zh) | 2018-03-16 |
| EP3505515B1 (en) | 2021-11-24 |
| IL264673B (en) | 2019-11-28 |
| SA519401004B1 (ar) | 2021-10-06 |
| DK3505515T3 (da) | 2022-01-24 |
| US20210198236A1 (en) | 2021-07-01 |
| HUE057370T2 (hu) | 2022-05-28 |
| EP3505515A1 (en) | 2019-07-03 |
| TWI702210B (zh) | 2020-08-21 |
| US11834431B2 (en) | 2023-12-05 |
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