PH12018500358A1 - Compounds for use in an antibacterial applications - Google Patents

Compounds for use in an antibacterial applications

Info

Publication number
PH12018500358A1
PH12018500358A1 PH12018500358A PH12018500358A PH12018500358A1 PH 12018500358 A1 PH12018500358 A1 PH 12018500358A1 PH 12018500358 A PH12018500358 A PH 12018500358A PH 12018500358 A PH12018500358 A PH 12018500358A PH 12018500358 A1 PH12018500358 A1 PH 12018500358A1
Authority
PH
Philippines
Prior art keywords
compounds
antibacterial applications
antibacterial
applications
antibacterials
Prior art date
Application number
PH12018500358A
Other languages
English (en)
Inventor
Haifeng Cui
Alan Hennessy
Qi Jin
Timothy James Miles
Stephen Frederick Moss
Neil David Pearson
Original Assignee
Glaxosmithkline Ip Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Ip Dev Ltd filed Critical Glaxosmithkline Ip Dev Ltd
Publication of PH12018500358A1 publication Critical patent/PH12018500358A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53831,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
PH12018500358A 2015-08-16 2018-02-15 Compounds for use in an antibacterial applications PH12018500358A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562205732P 2015-08-16 2015-08-16
US201662308928P 2016-03-16 2016-03-16
PCT/IB2016/054890 WO2017029602A2 (en) 2015-08-16 2016-08-15 Compounds for use in antibacterial applications

Publications (1)

Publication Number Publication Date
PH12018500358A1 true PH12018500358A1 (en) 2018-09-03

Family

ID=57218948

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12018500358A PH12018500358A1 (en) 2015-08-16 2018-02-15 Compounds for use in an antibacterial applications

Country Status (22)

Country Link
US (2) US10364254B2 (https=)
EP (1) EP3334739A2 (https=)
JP (1) JP6757402B2 (https=)
KR (1) KR20180038046A (https=)
CN (1) CN108137616B (https=)
AU (2) AU2016307969C1 (https=)
CA (1) CA2995715A1 (https=)
CL (1) CL2018000403A1 (https=)
CO (1) CO2018002204A2 (https=)
CR (1) CR20180111A (https=)
DO (1) DOP2018000049A (https=)
EA (1) EA033314B1 (https=)
HK (1) HK1248680A1 (https=)
IL (1) IL257265B (https=)
MA (1) MA42621A (https=)
MX (1) MX2018002033A (https=)
PE (1) PE20181143A1 (https=)
PH (1) PH12018500358A1 (https=)
TW (1) TW201722965A (https=)
UY (1) UY36851A (https=)
WO (1) WO2017029602A2 (https=)
ZA (1) ZA201800722B (https=)

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TW201722965A (zh) * 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 用於抗菌應用之化合物
WO2019180634A1 (en) 2018-03-23 2019-09-26 Glaxosmithkline Intellectual Property Development Limited Synthesis of oxazinone-containing bicyclic aromatic and heteroaromatic aldehydes
TW202116782A (zh) 2019-07-16 2021-05-01 瑞士商愛杜西亞製藥有限公司 喹啉酮衍生物
CN111269247B (zh) * 2020-03-04 2020-11-24 河南科技大学第一附属医院 具有抑制大肠杆菌作用的噻嗪酮药物分子的制备方法
AU2023235233A1 (en) 2022-03-14 2024-09-12 Slap Pharmaceuticals Llc Multicyclic compounds
WO2025132870A1 (en) 2023-12-21 2025-06-26 Glaxosmithkline Intellectual Property (No.4) Limited Chemical compounds and uses thereof

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Also Published As

Publication number Publication date
US20190270755A1 (en) 2019-09-05
WO2017029602A2 (en) 2017-02-23
HK1248680A1 (zh) 2018-10-19
IL257265A (en) 2018-03-29
CN108137616A (zh) 2018-06-08
EP3334739A2 (en) 2018-06-20
US10683307B2 (en) 2020-06-16
PE20181143A1 (es) 2018-07-17
AU2019200226B2 (en) 2020-01-23
US10364254B2 (en) 2019-07-30
EA033314B1 (ru) 2019-09-30
CR20180111A (es) 2018-04-12
ZA201800722B (en) 2019-07-31
AU2016307969A1 (en) 2018-03-08
IL257265B (en) 2020-07-30
CN108137616B (zh) 2020-06-26
DOP2018000049A (es) 2018-03-30
MA42621A (fr) 2018-06-20
CA2995715A1 (en) 2017-02-23
KR20180038046A (ko) 2018-04-13
JP2018523675A (ja) 2018-08-23
AU2019200226A1 (en) 2019-01-31
JP6757402B2 (ja) 2020-09-16
AU2016307969C1 (en) 2019-09-05
CO2018002204A2 (es) 2018-06-20
WO2017029602A3 (en) 2017-04-13
TW201722965A (zh) 2017-07-01
AU2016307969B2 (en) 2019-02-14
UY36851A (es) 2017-03-31
EA201890412A1 (ru) 2018-08-31
US20190031680A1 (en) 2019-01-31
MX2018002033A (es) 2018-06-15
CL2018000403A1 (es) 2018-07-06

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