PH12014502685A1 - Amides of 2-amino-4-arylthiazole compounds and their salts - Google Patents
Amides of 2-amino-4-arylthiazole compounds and their saltsInfo
- Publication number
- PH12014502685A1 PH12014502685A1 PH12014502685A PH12014502685A PH12014502685A1 PH 12014502685 A1 PH12014502685 A1 PH 12014502685A1 PH 12014502685 A PH12014502685 A PH 12014502685A PH 12014502685 A PH12014502685 A PH 12014502685A PH 12014502685 A1 PH12014502685 A1 PH 12014502685A1
- Authority
- PH
- Philippines
- Prior art keywords
- salts
- amides
- amino
- arylthiazole compounds
- arylthiazole
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- 150000001408 amides Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- XOPMVFNBFICPDB-UHFFFAOYSA-N n-[4-[2,4-difluoro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]-2-(1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide Chemical class C1=2C(=O)N(C)C(=O)N(C)C=2SC=C1CC(=O)NC(SC=1)=NC=1C1=CC=C(F)C(C(F)(F)F)=C1F XOPMVFNBFICPDB-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1687MU2012 | 2012-06-08 | ||
| US201261665282P | 2012-06-27 | 2012-06-27 | |
| IN3519MU2012 | 2012-12-13 | ||
| US201261748016P | 2012-12-31 | 2012-12-31 | |
| PCT/IB2013/054703 WO2013183035A2 (en) | 2012-06-08 | 2013-06-08 | Amides of 2-amino-4-arylthiazole compounds and their salts |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PH12014502685B1 PH12014502685B1 (en) | 2015-01-26 |
| PH12014502685A1 true PH12014502685A1 (en) | 2015-01-26 |
Family
ID=54193746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH12014502685A PH12014502685A1 (en) | 2012-06-08 | 2014-12-02 | Amides of 2-amino-4-arylthiazole compounds and their salts |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9458173B2 (enExample) |
| EP (1) | EP2858999B1 (enExample) |
| JP (1) | JP5989900B2 (enExample) |
| KR (1) | KR20150015488A (enExample) |
| CN (1) | CN104350058A (enExample) |
| AP (1) | AP3546A (enExample) |
| AU (1) | AU2013273118B2 (enExample) |
| BR (1) | BR112014029155A2 (enExample) |
| CA (1) | CA2873570C (enExample) |
| CL (1) | CL2014003317A1 (enExample) |
| EA (1) | EA031334B1 (enExample) |
| HK (1) | HK1207643A1 (enExample) |
| IL (1) | IL236084A0 (enExample) |
| IN (1) | IN2014MN02467A (enExample) |
| MX (1) | MX354014B (enExample) |
| MY (1) | MY165622A (enExample) |
| NZ (1) | NZ701721A (enExample) |
| PE (1) | PE20142306A1 (enExample) |
| PH (1) | PH12014502685A1 (enExample) |
| SG (1) | SG11201408093PA (enExample) |
| WO (1) | WO2013183035A2 (enExample) |
| ZA (1) | ZA201500082B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ724503A (en) | 2012-06-08 | 2017-12-22 | Gilead Sciences Inc | Macrocyclic inhibitors of flaviviridae viruses |
| AR091279A1 (es) | 2012-06-08 | 2015-01-21 | Gilead Sciences Inc | Inhibidores macrociclicos de virus flaviviridae |
| MX2015016024A (es) * | 2013-06-20 | 2016-04-04 | Glenmark Pharmaceuticals Sa | Formulacion en nanoparticulas que comprende un antagonista para trpa1. |
| JP6573968B2 (ja) * | 2014-08-11 | 2019-09-11 | ハイドラ バイオサイエンシズ インコーポレイテッドＨｙｄｒａ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． | ＴＲＰＣ５調節因子としての、精神神経障害の処置のためのチエノおよびフロ［２，３−ｄ］ピリミジン−２，４［１Ｈ，３Ｈ］−ジオン誘導体 |
| WO2016042501A1 (en) * | 2014-09-16 | 2016-03-24 | Glenmark Pharmaceuticals S.A. | Trpa1 antagonist for the treatment of pain associated to diabetic neuropathic pain |
| TW202321229A (zh) | 2021-08-18 | 2023-06-01 | 美商富曼西公司 | 殺真菌的取代的雜環化合物 |
| CN114671875A (zh) * | 2022-04-27 | 2022-06-28 | 成都施贝康生物医药科技有限公司 | 新型二氢嘧啶类化合物、异构体或盐及其制备方法和用途 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2248231A1 (de) | 1972-10-02 | 1974-04-11 | Basf Ag | 3-aminoisothiazolo eckige klammer auf 3,4-d eckige klammer zu pyrimidine |
| SE9701398D0 (sv) | 1997-04-15 | 1997-04-15 | Astra Pharma Prod | Novel compounds |
| ES2193839B1 (es) * | 2001-06-22 | 2005-02-16 | Almirall Prodesfarma, S.A. | Nuevos derivados de 6-fenildihidropirrolpirimidindiona. |
| AU2003253165A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Pyrimidine fused bicyclic metalloproteinase inhibitors |
| US6890923B2 (en) | 2002-12-16 | 2005-05-10 | Astrazeneca Ab | Compounds |
| US7465581B2 (en) | 2002-12-18 | 2008-12-16 | The Scripps Research Institute | ANKTM1, a cold-activated TRP-like channel expressed in nociceptive neurons |
| CA2536313A1 (en) * | 2003-08-22 | 2005-03-03 | Takeda Pharmaceutical Company Limited | Fused pyrimidine derivative and use thereof |
| US20070099940A1 (en) | 2004-02-11 | 2007-05-03 | Spearing Paul K | Pth agonists |
| US20070196866A1 (en) | 2004-03-13 | 2007-08-23 | Irm Llc | Modulators of ion channel trpa1 |
| EP1847541A4 (en) | 2005-02-03 | 2009-12-30 | Takeda Pharmaceutical | CONDENSED PYRIMIDINE DERIVATIVE AND USE THEREOF |
| US20070032531A1 (en) | 2005-08-04 | 2007-02-08 | Apogee Biotechnology Corporation | Sphingosine kinase inhibitors and methods of their use |
| US20070105920A1 (en) | 2005-11-08 | 2007-05-10 | Akzo Nobel N.V. | 2-(Benzimidazol-1-Yl)-N-(4-phenylthiazol-2-yl) acetamide derivatives |
| CN102499921A (zh) | 2005-12-22 | 2012-06-20 | 海德拉生物科学公司 | 治疗疼痛的方法和组合物 |
| CN101454318A (zh) * | 2006-03-22 | 2009-06-10 | 阿斯利康(瑞典)有限公司 | 吡啶并嘧啶衍生物及其作为pde4抑制剂的用途 |
| TW200800997A (en) | 2006-03-22 | 2008-01-01 | Astrazeneca Ab | Chemical compounds |
| JP2011201776A (ja) | 2008-07-23 | 2011-10-13 | Mochida Pharmaceut Co Ltd | ヘテロシクリデン−ｎ−（３，４−ジヒドロ−２（１ｈ）−キナゾリノン−５−イル）アセトアミド誘導体 |
| CL2008000252A1 (es) | 2007-01-29 | 2008-03-14 | Xenon Pharmaceuticals Inc | Compuestos derivados de quinazolinona o pirimidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar enfermedades mediadas por los canales de calcio, tales como dolor, depresion, enfermedades cardiovasculares, respir |
| CA2691468C (en) | 2007-06-22 | 2017-05-09 | Hydra Biosciences, Inc. | Substituted xanthine compounds and methods to treat diseases mediated by trpa1 |
| US7951814B2 (en) * | 2008-06-17 | 2011-05-31 | Glenmark Pharmaceuticals, S.A. | Quinazolinedione derivatives as TRPA1 modulators |
| WO2009158719A2 (en) | 2008-06-27 | 2009-12-30 | Hydra Biosciences, Inc. | Methods and compositions for treating disorders |
| KR20110128898A (ko) | 2009-03-23 | 2011-11-30 | 그렌마크 파머수티칼스 에스. 아. | Ｔｒｐａ1 조절자로서 푸로피리미딘디온 유도체 |
| AU2010227245B2 (en) | 2009-03-23 | 2015-09-10 | Glenmark Pharmaceuticals S.A. | Fused pyrimidine-dione derivatives as TRPA1 modulators |
| US8623880B2 (en) | 2009-03-23 | 2014-01-07 | Glenmark Pharmaceuticals S.A. | Fused pyrimidine-dione derivatives as TRPA1 modulators |
| ES2424340T3 (es) | 2009-03-23 | 2013-10-01 | Glenmark Pharmaceuticals S.A. | Derivados de isotiazolo-pirimidindiona como moduladores de TRPA1 |
| MY159059A (en) | 2010-12-20 | 2016-12-15 | Glenmark Pharmaceuticals Sa | 2-amino-4-arylthiazole compounds as trpa1 antagonists |
-
2013
- 2013-06-08 JP JP2015515642A patent/JP5989900B2/ja not_active Expired - Fee Related
- 2013-06-08 CA CA2873570A patent/CA2873570C/en active Active
- 2013-06-08 WO PCT/IB2013/054703 patent/WO2013183035A2/en not_active Ceased
- 2013-06-08 AP AP2014008076A patent/AP3546A/xx active
- 2013-06-08 MY MYPI2014003389A patent/MY165622A/en unknown
- 2013-06-08 PE PE2014002226A patent/PE20142306A1/es not_active Application Discontinuation
- 2013-06-08 EP EP13742279.6A patent/EP2858999B1/en active Active
- 2013-06-08 HK HK15108333.2A patent/HK1207643A1/xx unknown
- 2013-06-08 CN CN201380030184.XA patent/CN104350058A/zh active Pending
- 2013-06-08 AU AU2013273118A patent/AU2013273118B2/en not_active Ceased
- 2013-06-08 KR KR1020147033855A patent/KR20150015488A/ko not_active Abandoned
- 2013-06-08 SG SG11201408093PA patent/SG11201408093PA/en unknown
- 2013-06-08 IN IN2467MUN2014 patent/IN2014MN02467A/en unknown
- 2013-06-08 US US14/402,608 patent/US9458173B2/en not_active Expired - Fee Related
- 2013-06-08 EA EA201492054A patent/EA031334B1/ru unknown
- 2013-06-08 BR BR112014029155A patent/BR112014029155A2/pt not_active Application Discontinuation
- 2013-06-08 MX MX2014014482A patent/MX354014B/es active IP Right Grant
- 2013-06-08 NZ NZ701721A patent/NZ701721A/en not_active IP Right Cessation
-
2014
- 2014-12-02 PH PH12014502685A patent/PH12014502685A1/en unknown
- 2014-12-04 IL IL236084A patent/IL236084A0/en unknown
- 2014-12-04 CL CL2014003317A patent/CL2014003317A1/es unknown
-
2015
- 2015-01-07 ZA ZA2015/00082A patent/ZA201500082B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2013273118A1 (en) | 2014-11-27 |
| JP5989900B2 (ja) | 2016-09-07 |
| IL236084A0 (en) | 2015-02-01 |
| MY165622A (en) | 2018-04-18 |
| EP2858999A2 (en) | 2015-04-15 |
| EP2858999B1 (en) | 2017-05-10 |
| PH12014502685B1 (en) | 2015-01-26 |
| US20150111038A1 (en) | 2015-04-23 |
| CL2014003317A1 (es) | 2015-02-13 |
| AP3546A (en) | 2016-01-14 |
| WO2013183035A3 (en) | 2014-02-27 |
| AP2014008076A0 (en) | 2014-11-30 |
| CA2873570C (en) | 2016-11-01 |
| BR112014029155A2 (pt) | 2017-06-27 |
| PE20142306A1 (es) | 2015-01-16 |
| MX2014014482A (es) | 2015-06-05 |
| NZ701721A (en) | 2016-03-31 |
| KR20150015488A (ko) | 2015-02-10 |
| SG11201408093PA (en) | 2015-01-29 |
| EA201492054A1 (ru) | 2016-08-31 |
| AU2013273118B2 (en) | 2015-11-05 |
| HK1207643A1 (en) | 2016-02-05 |
| MX354014B (es) | 2018-02-08 |
| ZA201500082B (en) | 2015-12-23 |
| CA2873570A1 (en) | 2013-12-12 |
| US9458173B2 (en) | 2016-10-04 |
| WO2013183035A2 (en) | 2013-12-12 |
| CN104350058A (zh) | 2015-02-11 |
| EA031334B1 (ru) | 2018-12-28 |
| JP2015520183A (ja) | 2015-07-16 |
| IN2014MN02467A (enExample) | 2015-07-10 |
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