JO3248B1 - عملية لتحضير إنزيمات مثبطة من نوع c-fms - Google Patents

عملية لتحضير إنزيمات مثبطة من نوع c-fms

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Publication number
JO3248B1
JO3248B1 JOP/2013/0237A JOP20130237A JO3248B1 JO 3248 B1 JO3248 B1 JO 3248B1 JO P20130237 A JOP20130237 A JO P20130237A JO 3248 B1 JO3248 B1 JO 3248B1
Authority
JO
Jordan
Prior art keywords
preparation
kinase inhibitors
fms kinase
fms
inhibitors
Prior art date
Application number
JOP/2013/0237A
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English (en)
Inventor
Elisabeth Stappers Alfred
Kolodziejczyk Krzysztof
A Teleha Christopher
Johan Herman Weerts Koen
Original Assignee
Janssen Pharmaceutica Nv
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Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of JO3248B1 publication Critical patent/JO3248B1/ar

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Abstract

هذا الاختراع موجه لإعداد طريقة لتحضير مشتقات حلقية مخلطة لها الصيغة ( I ): حيث كل من J، X، Zو R2 كما هي معرفة في هذا الاختراع. وتلك المركبات تفيد كمثبطات بروتين تيروزين كيناز، وعلى الأخص مثبطات c-fms كيناز.
JOP/2013/0237A 2012-08-07 2013-08-06 عملية لتحضير إنزيمات مثبطة من نوع c-fms JO3248B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261680446P 2012-08-07 2012-08-07

Publications (1)

Publication Number Publication Date
JO3248B1 true JO3248B1 (ar) 2018-09-16

Family

ID=48980367

Family Applications (2)

Application Number Title Priority Date Filing Date
JOP/2018/0012A JOP20180012A1 (ar) 2012-08-07 2012-08-07 عملية السلفنة باستخدام نونافلوروبوتانيسولفونيل فلوريد
JOP/2013/0237A JO3248B1 (ar) 2012-08-07 2013-08-06 عملية لتحضير إنزيمات مثبطة من نوع c-fms

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JOP/2018/0012A JOP20180012A1 (ar) 2012-08-07 2012-08-07 عملية السلفنة باستخدام نونافلوروبوتانيسولفونيل فلوريد

Country Status (13)

Country Link
US (2) US9029352B2 (ar)
EP (2) EP3091006B1 (ar)
JP (1) JP6290884B2 (ar)
CN (2) CN104520295B (ar)
AR (2) AR092070A1 (ar)
AU (2) AU2013299926B2 (ar)
ES (2) ES2658773T3 (ar)
HK (2) HK1209418A1 (ar)
IN (1) IN2015DN00660A (ar)
JO (2) JOP20180012A1 (ar)
TW (2) TWI646090B (ar)
UY (1) UY34972A (ar)
WO (1) WO2014025679A1 (ar)

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TWI752980B (zh) * 2016-07-18 2022-01-21 比利時商健生藥品公司 4-氰基-n-(2-(4,4-二甲基環己-1-烯-1-基)-6-(2,2,6,6-四甲基四氫-2h-哌喃-4-基)吡啶-3-基)-1h-咪唑-2-甲醯胺之晶型
TW201811326A (zh) 2016-07-18 2018-04-01 比利時商健生藥品公司 ４－氰基－ｎ－（２－（４，４－二甲基環己－１－烯－１－基）－６－（２，２，６，６－四甲基四氫－２ｈ－哌喃－４－基）吡啶－３－基）－１ｈ－咪唑－２－甲醯胺之鹽形式
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