PE84399A1 - Formas de dosificacion de sertralina de liberacion retardada - Google Patents
Formas de dosificacion de sertralina de liberacion retardadaInfo
- Publication number
- PE84399A1 PE84399A1 PE1998000577A PE00057798A PE84399A1 PE 84399 A1 PE84399 A1 PE 84399A1 PE 1998000577 A PE1998000577 A PE 1998000577A PE 00057798 A PE00057798 A PE 00057798A PE 84399 A1 PE84399 A1 PE 84399A1
- Authority
- PE
- Peru
- Prior art keywords
- nucleus
- sertraline
- water
- phthalate
- membrane
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Biophysics (AREA)
- Child & Adolescent Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
CARACTERIZADA PORQUE COMPRENDE UN NUCLEO DE LIBERACION INMEDIATA DE SERTRALINA RECUBIERTO CON UN POLIMERO IMPERMEABLE AL pH DEL ESTOMAGO, PERO PERMEABLE AL pH DEL INTESTINO DELGADO; EL POLIMERO SE SELECCIONA DE ACETATO DE FTALATO DE CELULOSA, POLI(ACETATO-FTALATO DE VINILO), FTALATO DE HIDROXIPROPILHIPROMELOSA, ENTRE OTROS; EL NUCLEO PUEDE SER MULTIPARTICULADO, UN COMPRIMIDO, UNA CAPSULA, O UNA CAPSULA DE GELATINA; EL NUCLEO ES SENSIBLE AL pH Y A LAS ENZIMAS. TAMBIEN SE REFIERE A OTRA FORMA DE DOSIFICACION QUE COMPRENDE UN NUCLEO, UNA MEMBRANA QUE RODEA AL NUCLEO, QUE PUEDE SER DE UN MATERIAL HIDROFOBO MICROPOROSO Y UN LIQUIDO HIDROFOBO ATRAPADO EN LOS POROS DE DICHA MEMBRANA, SIENDO DICHO LIQUIDO IMPERMEABLE AL AGUA Y A LA SERTRALINA, PERO CAMBIA POR DEGRADACION ENZIMATICA, RESULTANDO LA MEMBRANA PERMEABLE AL AGUA Y A LA SERTRALINA EN EL INTESTINO DELGADO. EL NUCLEO TAMBIEN PUEDE COMPRENDER UN AGENTE OSMOTICO. EL RECUBRIMIENTO ES SOLUBLE EN AGUA O DISGREGABLE EN AGUA. LA FORMA DE DOSIFICACION PERMITE LA LIBERACION DE NO MAS DE 10% DE SERTRALINA EN EL ESTOMAGO; PUDIENDO SER UTIL PARA TRATAR UNA ENFERMEDAD PSIQUIATRICA, EYACULACION PRECOZ, DEPENDENCIA QUIMICA, TRASTORNO DISFORICO PREMESTRUAL U OBESIDAD
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5149997P | 1997-07-01 | 1997-07-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE84399A1 true PE84399A1 (es) | 1999-09-11 |
Family
ID=21971681
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1998000577A PE84399A1 (es) | 1997-07-01 | 1998-06-26 | Formas de dosificacion de sertralina de liberacion retardada |
Country Status (41)
Country | Link |
---|---|
EP (1) | EP1007024B1 (es) |
JP (1) | JP3786715B2 (es) |
KR (1) | KR100369698B1 (es) |
CN (4) | CN1475209A (es) |
AP (1) | AP1199A (es) |
AR (1) | AR038394A2 (es) |
AT (1) | ATE245415T1 (es) |
AU (1) | AU727152B2 (es) |
BG (1) | BG64742B1 (es) |
BR (1) | BR9809895A (es) |
CA (1) | CA2290969C (es) |
DE (1) | DE69816624T2 (es) |
DK (1) | DK1007024T3 (es) |
DZ (1) | DZ2547A1 (es) |
EA (1) | EA001906B1 (es) |
ES (1) | ES2202858T3 (es) |
GT (1) | GT199800091A (es) |
HK (1) | HK1027982A1 (es) |
HN (1) | HN1998000099A (es) |
HR (1) | HRP980376B1 (es) |
HU (1) | HUP0301787A3 (es) |
ID (1) | ID23187A (es) |
IL (2) | IL152304A0 (es) |
IS (1) | IS5267A (es) |
MA (1) | MA24585A1 (es) |
NO (1) | NO996519L (es) |
NZ (1) | NZ501249A (es) |
OA (1) | OA11247A (es) |
PA (1) | PA8454201A1 (es) |
PE (1) | PE84399A1 (es) |
PL (1) | PL337799A1 (es) |
PT (1) | PT1007024E (es) |
SI (1) | SI1007024T1 (es) |
SK (1) | SK173299A3 (es) |
TN (1) | TNSN98122A1 (es) |
TR (1) | TR199903295T2 (es) |
TW (1) | TW575437B (es) |
UA (1) | UA63953C2 (es) |
UY (1) | UY25068A1 (es) |
WO (1) | WO1999001122A1 (es) |
ZA (1) | ZA985710B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL142896A0 (en) | 1998-11-02 | 2002-04-21 | Elan Corp Plc | Multiparticulate modified release composition |
IE990406A1 (en) | 1999-05-20 | 2000-12-27 | Elan Corp Plc | Multiparticulate controlled release selective serotonin reuptake inhibitor formulations. |
DZ3256A1 (fr) * | 1999-05-20 | 2000-11-30 | Elan Corp Plc | Preparations d'inhibiteurs specifiques du recaptage de la serotonine a liberation multiparticulaire regulee |
ES2393582T3 (es) | 1999-09-03 | 2012-12-26 | Apbi Holdings, Llc | Procedimiento de utilización de inhibidores de la recaptación de serotonina selectivos de inicio rápido de acción para el tratamiento de las disfunciones sexuales |
ES2168043B1 (es) * | 1999-09-13 | 2003-04-01 | Esteve Labor Dr | Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido. |
BRPI0108145B8 (pt) * | 2000-02-10 | 2021-05-25 | Bpsi Holdings Inc | composições de revestimento entérico acrílicas |
MXPA03001771A (es) | 2000-08-30 | 2003-06-04 | Pfizer Prod Inc | Formulaciones de liberacion sostenida para secretagogos de hormona del crecimiento. |
US6482440B2 (en) * | 2000-09-21 | 2002-11-19 | Phase 2 Discovery, Inc. | Long acting antidepressant microparticles |
MXPA03008997A (es) * | 2001-04-10 | 2004-02-12 | Sun Pharmaceutical Ind Ltd | Composicion de liberacion por impulso temporizado. |
WO2003013480A1 (en) * | 2001-08-06 | 2003-02-20 | Dr. Reddy's Laboratories Ltd. | Improved enteric formulation of fluoxetin |
GB0607534D0 (en) * | 2006-04-13 | 2006-05-24 | Univ London Pharmacy | Colonic drug delivery formulation |
EP2586429A1 (en) * | 2011-10-26 | 2013-05-01 | Freund Pharmatec Ltd. | Multi-unit drug delivery device for pulsatile or sustained release |
CN108014087A (zh) * | 2017-12-27 | 2018-05-11 | 江苏联环药业股份有限公司 | 一种盐酸舍曲林胶囊的制备方法 |
CN109432038A (zh) * | 2018-12-28 | 2019-03-08 | 乐普制药科技有限公司 | 一种含有盐酸舍曲林的肠溶片剂及其制备方法 |
CN114129540B (zh) * | 2021-11-19 | 2022-07-05 | 浙江维康药业股份有限公司 | 一种肝苏胶囊及其制作方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK150008C (da) * | 1981-11-20 | 1987-05-25 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat |
US4803076A (en) * | 1986-09-04 | 1989-02-07 | Pfizer Inc. | Controlled release device for an active substance |
EP0357364B1 (en) * | 1988-08-30 | 1993-07-28 | E.I. Du Pont De Nemours And Company | A process for flash-spinning dry polymeric plexifilamentary film-fibril strands |
IL91398A (en) * | 1988-08-30 | 1994-05-30 | Pfizer | A device for the controlled release of pneumatic substances, including the active substance, surrounded by an asymmetric membrane |
US4983401A (en) * | 1989-05-22 | 1991-01-08 | Kinaform Technology, Inc. | Sustained release pharmaceutical preparations having pH controlled membrane coatings |
-
1998
- 1998-06-16 NZ NZ501249A patent/NZ501249A/en unknown
- 1998-06-16 AU AU75451/98A patent/AU727152B2/en not_active Ceased
- 1998-06-16 ES ES98923022T patent/ES2202858T3/es not_active Expired - Lifetime
- 1998-06-16 ID IDW991698A patent/ID23187A/id unknown
- 1998-06-16 TR TR1999/03295T patent/TR199903295T2/xx unknown
- 1998-06-16 SK SK1732-99A patent/SK173299A3/sk unknown
- 1998-06-16 CN CNA031489737A patent/CN1475209A/zh active Pending
- 1998-06-16 EP EP98923022A patent/EP1007024B1/en not_active Expired - Lifetime
- 1998-06-16 PT PT98923022T patent/PT1007024E/pt unknown
- 1998-06-16 UA UA99116392A patent/UA63953C2/uk unknown
- 1998-06-16 WO PCT/IB1998/000937 patent/WO1999001122A1/en not_active Application Discontinuation
- 1998-06-16 CN CNA200310118311XA patent/CN1494899A/zh active Pending
- 1998-06-16 HU HU0301787A patent/HUP0301787A3/hu unknown
- 1998-06-16 KR KR10-1999-7011529A patent/KR100369698B1/ko not_active IP Right Cessation
- 1998-06-16 AT AT98923022T patent/ATE245415T1/de not_active IP Right Cessation
- 1998-06-16 PL PL98337799A patent/PL337799A1/xx unknown
- 1998-06-16 IL IL15230498A patent/IL152304A0/xx unknown
- 1998-06-16 JP JP50677799A patent/JP3786715B2/ja not_active Expired - Fee Related
- 1998-06-16 CN CNB988064294A patent/CN1151783C/zh not_active Expired - Fee Related
- 1998-06-16 DK DK98923022T patent/DK1007024T3/da active
- 1998-06-16 BR BR9809895-0A patent/BR9809895A/pt not_active Application Discontinuation
- 1998-06-16 IL IL13308198A patent/IL133081A/xx not_active IP Right Cessation
- 1998-06-16 SI SI9830494T patent/SI1007024T1/xx unknown
- 1998-06-16 CA CA002290969A patent/CA2290969C/en not_active Expired - Fee Related
- 1998-06-16 DE DE69816624T patent/DE69816624T2/de not_active Expired - Fee Related
- 1998-06-16 CN CNA031489729A patent/CN1475208A/zh active Pending
- 1998-06-16 EA EA199900965A patent/EA001906B1/ru unknown
- 1998-06-25 PA PA19988454201A patent/PA8454201A1/es unknown
- 1998-06-25 AP APAP/P/1998/001278A patent/AP1199A/en active
- 1998-06-25 TW TW087110269A patent/TW575437B/zh active
- 1998-06-26 PE PE1998000577A patent/PE84399A1/es not_active Application Discontinuation
- 1998-06-29 UY UY25068A patent/UY25068A1/es not_active IP Right Cessation
- 1998-06-29 GT GT199800091A patent/GT199800091A/es unknown
- 1998-06-30 TN TNTNSN98122A patent/TNSN98122A1/fr unknown
- 1998-06-30 MA MA25144A patent/MA24585A1/fr unknown
- 1998-06-30 ZA ZA9805710A patent/ZA985710B/xx unknown
- 1998-06-30 HN HN1998000099A patent/HN1998000099A/es unknown
- 1998-06-30 DZ DZ980157A patent/DZ2547A1/xx active
- 1998-07-01 HR HR980376A patent/HRP980376B1/xx not_active IP Right Cessation
-
1999
- 1999-11-23 IS IS5267A patent/IS5267A/is unknown
- 1999-11-23 BG BG103916A patent/BG64742B1/bg unknown
- 1999-12-23 OA OA9900307A patent/OA11247A/en unknown
- 1999-12-28 NO NO996519A patent/NO996519L/no not_active Application Discontinuation
-
2000
- 2000-11-23 HK HK00107492A patent/HK1027982A1/xx not_active IP Right Cessation
-
2003
- 2003-02-05 AR ARP030100364A patent/AR038394A2/es active IP Right Grant
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration | ||
FD | Application declared void or lapsed |