AR033943A1 - Un dispositivo para la liberacion controlada de agentes activos a un ambiente de uso - Google Patents

Un dispositivo para la liberacion controlada de agentes activos a un ambiente de uso

Info

Publication number
AR033943A1
AR033943A1 ARP000102605A ARP000102605A AR033943A1 AR 033943 A1 AR033943 A1 AR 033943A1 AR P000102605 A ARP000102605 A AR P000102605A AR P000102605 A ARP000102605 A AR P000102605A AR 033943 A1 AR033943 A1 AR 033943A1
Authority
AR
Argentina
Prior art keywords
environment
controlled release
active substance
active agents
composition
Prior art date
Application number
ARP000102605A
Other languages
English (en)
Inventor
Joaquina Faour
Original Assignee
Osmotica Argentina S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osmotica Argentina S A filed Critical Osmotica Argentina S A
Publication of AR033943A1 publication Critical patent/AR033943A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Abstract

Un dispositivo para la liberación controlada de sustancias activas, preferiblemente terapéuticamente activas, mediante una liberación combinada por difusión y por bombeo osmótico. El dispositivo (1) comprende un núcleo (2) localizado aproximadamente en el centro del dispositivo que comprende por lo menos un polímero hidrofílico expansible y opcionalmente un osmoagente; una composición (3) que rodea inmediatamente el núcleo, que contiene una sustancia activa y opcionalmente uno o más osmoagentes y un osmopolímero; una membrana externa (4) que rodea inmediatamente a la composición de sustancia activa, que comprende una mezcla de acilato de celulosa, un copolímero de una sal de poli(metacrilato) y un plastificante; y uno o más pasajes preformados (5) y una pluralidad de microporos en la membrana, que comunican la composición de sustancia activa con el exterior del dispositivo o ambiente de uso.
ARP000102605A 2000-01-14 2000-05-26 Un dispositivo para la liberacion controlada de agentes activos a un ambiente de uso AR033943A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/483,282 US6352721B1 (en) 2000-01-14 2000-01-14 Combined diffusion/osmotic pumping drug delivery system

Publications (1)

Publication Number Publication Date
AR033943A1 true AR033943A1 (es) 2004-01-21

Family

ID=23919455

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000102605A AR033943A1 (es) 2000-01-14 2000-05-26 Un dispositivo para la liberacion controlada de agentes activos a un ambiente de uso

Country Status (10)

Country Link
US (1) US6352721B1 (es)
EP (1) EP1253910B1 (es)
AR (1) AR033943A1 (es)
AU (1) AU2001227723A1 (es)
BR (1) BR0107621A (es)
CA (1) CA2396258C (es)
ES (1) ES2392396T3 (es)
MX (1) MXPA02006869A (es)
UY (1) UY26527A1 (es)
WO (1) WO2001051035A1 (es)

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Also Published As

Publication number Publication date
AU2001227723A1 (en) 2001-07-24
MXPA02006869A (es) 2004-06-29
WO2001051035A1 (en) 2001-07-19
US6352721B1 (en) 2002-03-05
EP1253910A4 (en) 2005-07-20
ES2392396T3 (es) 2012-12-10
CA2396258A1 (en) 2001-07-19
EP1253910A1 (en) 2002-11-06
BR0107621A (pt) 2002-11-12
CA2396258C (en) 2008-05-13
EP1253910B1 (en) 2012-08-01
UY26527A1 (es) 2001-07-31

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