PE20142306A1 - Amidas de compuestos de 2-amino-4-ariltiazol y sus sales - Google Patents
Amidas de compuestos de 2-amino-4-ariltiazol y sus salesInfo
- Publication number
- PE20142306A1 PE20142306A1 PE2014002226A PE2014002226A PE20142306A1 PE 20142306 A1 PE20142306 A1 PE 20142306A1 PE 2014002226 A PE2014002226 A PE 2014002226A PE 2014002226 A PE2014002226 A PE 2014002226A PE 20142306 A1 PE20142306 A1 PE 20142306A1
- Authority
- PE
- Peru
- Prior art keywords
- aryltiazole
- amino
- compounds
- amidas
- salts
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 2
- WZKSXHQDXQKIQJ-UHFFFAOYSA-N F[C](F)F Chemical group F[C](F)F WZKSXHQDXQKIQJ-UHFFFAOYSA-N 0.000 abstract 1
- -1 N- {4- [2 Chemical class 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical group [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1687MU2012 | 2012-06-08 | ||
| US201261665282P | 2012-06-27 | 2012-06-27 | |
| IN3519MU2012 | 2012-12-13 | ||
| US201261748016P | 2012-12-31 | 2012-12-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20142306A1 true PE20142306A1 (es) | 2015-01-16 |
Family
ID=54193746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2014002226A PE20142306A1 (es) | 2012-06-08 | 2013-06-08 | Amidas de compuestos de 2-amino-4-ariltiazol y sus sales |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9458173B2 (OSRAM) |
| EP (1) | EP2858999B1 (OSRAM) |
| JP (1) | JP5989900B2 (OSRAM) |
| KR (1) | KR20150015488A (OSRAM) |
| CN (1) | CN104350058A (OSRAM) |
| AP (1) | AP3546A (OSRAM) |
| AU (1) | AU2013273118B2 (OSRAM) |
| BR (1) | BR112014029155A2 (OSRAM) |
| CA (1) | CA2873570C (OSRAM) |
| CL (1) | CL2014003317A1 (OSRAM) |
| EA (1) | EA031334B1 (OSRAM) |
| HK (1) | HK1207643A1 (OSRAM) |
| IL (1) | IL236084A0 (OSRAM) |
| IN (1) | IN2014MN02467A (OSRAM) |
| MX (1) | MX354014B (OSRAM) |
| MY (1) | MY165622A (OSRAM) |
| NZ (1) | NZ701721A (OSRAM) |
| PE (1) | PE20142306A1 (OSRAM) |
| PH (1) | PH12014502685B1 (OSRAM) |
| SG (1) | SG11201408093PA (OSRAM) |
| WO (1) | WO2013183035A2 (OSRAM) |
| ZA (1) | ZA201500082B (OSRAM) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2875692A1 (en) | 2012-06-08 | 2013-12-12 | Selcia Limited | Macrocyclic inhibitors of flaviviridae viruses |
| AR091279A1 (es) | 2012-06-08 | 2015-01-21 | Gilead Sciences Inc | Inhibidores macrociclicos de virus flaviviridae |
| JP2016522251A (ja) | 2013-06-20 | 2016-07-28 | グレンマーク ファーマシューティカルズ， エセ．アー． | Ｔｒｐａ１アンタゴニストを含むナノ粒子製剤 |
| WO2016023832A1 (en) * | 2014-08-11 | 2016-02-18 | Hydra Biosciences, Inc. | Thieno- and furo[2,3-d]pyrimidine-2,4[1h,3h]-dione derivatives as trpc5 modulators for the treatment of neuropsychiatric disorders |
| US20190175599A1 (en) * | 2014-09-16 | 2019-06-13 | Glemark Pharmaceuticals S.A. | Trpa1 antagonist for the treatment of pain associated to diabetic neuropathic pain |
| TW202321229A (zh) | 2021-08-18 | 2023-06-01 | 美商富曼西公司 | 殺真菌的取代的雜環化合物 |
| CN114671875A (zh) * | 2022-04-27 | 2022-06-28 | 成都施贝康生物医药科技有限公司 | 新型二氢嘧啶类化合物、异构体或盐及其制备方法和用途 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2248231A1 (de) | 1972-10-02 | 1974-04-11 | Basf Ag | 3-aminoisothiazolo eckige klammer auf 3,4-d eckige klammer zu pyrimidine |
| SE9701398D0 (sv) | 1997-04-15 | 1997-04-15 | Astra Pharma Prod | Novel compounds |
| ES2193839B1 (es) | 2001-06-22 | 2005-02-16 | Almirall Prodesfarma, S.A. | Nuevos derivados de 6-fenildihidropirrolpirimidindiona. |
| WO2004014916A1 (en) | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Pyrimidine fused bicyclic metalloproteinase inhibitors |
| US6890923B2 (en) | 2002-12-16 | 2005-05-10 | Astrazeneca Ab | Compounds |
| AU2003290066A1 (en) | 2002-12-18 | 2004-07-09 | Novartis Ag | Anktm1, a cold-activated trp-like channel expressed in nociceptive neurons |
| WO2005019188A1 (ja) | 2003-08-22 | 2005-03-03 | Takeda Pharmaceutical Company Limited | 縮合ピリミジン誘導体およびその用途 |
| US20070099940A1 (en) | 2004-02-11 | 2007-05-03 | Spearing Paul K | Pth agonists |
| US20070196866A1 (en) | 2004-03-13 | 2007-08-23 | Irm Llc | Modulators of ion channel trpa1 |
| JPWO2006083005A1 (ja) | 2005-02-03 | 2008-06-26 | 武田薬品工業株式会社 | 縮合ピリミジン誘導体およびその用途 |
| JP2009503107A (ja) | 2005-08-04 | 2009-01-29 | アポジー・バイオテクノロジー・コーポレイション | スフィンゴシンキナーゼ阻害剤およびそれらの使用方法 |
| US20070105920A1 (en) | 2005-11-08 | 2007-05-10 | Akzo Nobel N.V. | 2-(Benzimidazol-1-Yl)-N-(4-phenylthiazol-2-yl) acetamide derivatives |
| TWI610684B (zh) * | 2005-12-22 | 2018-01-11 | 海卓勒生物科學公司 | 用於調節ｔｒｐａ１功能之化合物 |
| CN101454318A (zh) * | 2006-03-22 | 2009-06-10 | 阿斯利康(瑞典)有限公司 | 吡啶并嘧啶衍生物及其作为pde4抑制剂的用途 |
| TW200800997A (en) | 2006-03-22 | 2008-01-01 | Astrazeneca Ab | Chemical compounds |
| JP2011201776A (ja) | 2008-07-23 | 2011-10-13 | Mochida Pharmaceut Co Ltd | ヘテロシクリデン−ｎ−（３，４−ジヒドロ−２（１ｈ）−キナゾリノン−５−イル）アセトアミド誘導体 |
| AR065081A1 (es) | 2007-01-29 | 2009-05-13 | Xenon Pharmaceuticals Inc | Compuestos de quinazolinona y pirimidona fusionados y composicion farmaceutica |
| DK2170309T3 (en) | 2007-06-22 | 2017-01-09 | Hydra Biosciences Inc | Dioxo-2,6, -2,3-dihydro-1H-purine compounds useful in the treatment of diseases related to activity of TRPA1 channel |
| WO2010004390A1 (en) * | 2008-06-17 | 2010-01-14 | Glenmark Pharmaceuticals, S.A. | Quinazoline dione derivatives as trpa1 modulators |
| WO2009158719A2 (en) | 2008-06-27 | 2009-12-30 | Hydra Biosciences, Inc. | Methods and compositions for treating disorders |
| CN102361874A (zh) * | 2009-03-23 | 2012-02-22 | 格兰马克药品股份有限公司 | 作为trpa1调节剂的呋喃并嘧啶二酮衍生物 |
| US8623880B2 (en) | 2009-03-23 | 2014-01-07 | Glenmark Pharmaceuticals S.A. | Fused pyrimidine-dione derivatives as TRPA1 modulators |
| PT2411397E (pt) | 2009-03-23 | 2013-06-06 | Glenmark Pharmaceuticals Sa | Derivados de isotiazolo-pirimidinadiona como moduladores de trpa1 |
| MX2011009824A (es) | 2009-03-23 | 2012-01-25 | Glenmark Pharmaceuticals Sa | Derivados de pirimidina-diona fusionados como moduladores del trpa1. |
| EA023141B1 (ru) | 2010-12-20 | 2016-04-29 | Гленмарк Фармасьютикалс С.А. | Соединения 2-амино-4-арилтиазола в качестве антагонистов trpa1 |
-
2013
- 2013-06-08 JP JP2015515642A patent/JP5989900B2/ja not_active Expired - Fee Related
- 2013-06-08 PE PE2014002226A patent/PE20142306A1/es not_active Application Discontinuation
- 2013-06-08 EP EP13742279.6A patent/EP2858999B1/en active Active
- 2013-06-08 AU AU2013273118A patent/AU2013273118B2/en not_active Ceased
- 2013-06-08 HK HK15108333.2A patent/HK1207643A1/xx unknown
- 2013-06-08 EA EA201492054A patent/EA031334B1/ru unknown
- 2013-06-08 CA CA2873570A patent/CA2873570C/en active Active
- 2013-06-08 MY MYPI2014003389A patent/MY165622A/en unknown
- 2013-06-08 US US14/402,608 patent/US9458173B2/en not_active Expired - Fee Related
- 2013-06-08 BR BR112014029155A patent/BR112014029155A2/pt not_active Application Discontinuation
- 2013-06-08 IN IN2467MUN2014 patent/IN2014MN02467A/en unknown
- 2013-06-08 KR KR1020147033855A patent/KR20150015488A/ko not_active Abandoned
- 2013-06-08 MX MX2014014482A patent/MX354014B/es active IP Right Grant
- 2013-06-08 CN CN201380030184.XA patent/CN104350058A/zh active Pending
- 2013-06-08 SG SG11201408093PA patent/SG11201408093PA/en unknown
- 2013-06-08 WO PCT/IB2013/054703 patent/WO2013183035A2/en not_active Ceased
- 2013-06-08 AP AP2014008076A patent/AP3546A/xx active
- 2013-06-08 NZ NZ701721A patent/NZ701721A/en not_active IP Right Cessation
-
2014
- 2014-12-02 PH PH12014502685A patent/PH12014502685B1/en unknown
- 2014-12-04 IL IL236084A patent/IL236084A0/en unknown
- 2014-12-04 CL CL2014003317A patent/CL2014003317A1/es unknown
-
2015
- 2015-01-07 ZA ZA2015/00082A patent/ZA201500082B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CL2014003317A1 (es) | 2015-02-13 |
| AP3546A (en) | 2016-01-14 |
| IL236084A0 (en) | 2015-02-01 |
| PH12014502685A1 (en) | 2015-01-26 |
| JP5989900B2 (ja) | 2016-09-07 |
| PH12014502685B1 (en) | 2015-01-26 |
| US20150111038A1 (en) | 2015-04-23 |
| MX2014014482A (es) | 2015-06-05 |
| EA031334B1 (ru) | 2018-12-28 |
| AU2013273118B2 (en) | 2015-11-05 |
| CN104350058A (zh) | 2015-02-11 |
| EA201492054A1 (ru) | 2016-08-31 |
| NZ701721A (en) | 2016-03-31 |
| BR112014029155A2 (pt) | 2017-06-27 |
| MY165622A (en) | 2018-04-18 |
| MX354014B (es) | 2018-02-08 |
| ZA201500082B (en) | 2015-12-23 |
| HK1207643A1 (en) | 2016-02-05 |
| US9458173B2 (en) | 2016-10-04 |
| EP2858999A2 (en) | 2015-04-15 |
| EP2858999B1 (en) | 2017-05-10 |
| SG11201408093PA (en) | 2015-01-29 |
| WO2013183035A2 (en) | 2013-12-12 |
| IN2014MN02467A (OSRAM) | 2015-07-10 |
| KR20150015488A (ko) | 2015-02-10 |
| WO2013183035A3 (en) | 2014-02-27 |
| JP2015520183A (ja) | 2015-07-16 |
| AP2014008076A0 (en) | 2014-11-30 |
| CA2873570C (en) | 2016-11-01 |
| CA2873570A1 (en) | 2013-12-12 |
| AU2013273118A1 (en) | 2014-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |