IN2014MN02467A - - Google Patents
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- Publication number
- IN2014MN02467A IN2014MN02467A IN2467MUN2014A IN2014MN02467A IN 2014MN02467 A IN2014MN02467 A IN 2014MN02467A IN 2467MUN2014 A IN2467MUN2014 A IN 2467MUN2014A IN 2014MN02467 A IN2014MN02467 A IN 2014MN02467A
- Authority
- IN
- India
- Prior art keywords
- tetrahydrothieno
- thiazol
- dioxo
- pyrimidin
- difluoro
- Prior art date
Links
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 2
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- PQIOSYKVBBWRRI-UHFFFAOYSA-N methylphosphonyl difluoride Chemical group CP(F)(F)=O PQIOSYKVBBWRRI-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004528 pyrimidin-5-yl group Chemical group N1=CN=CC(=C1)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000437 thiazol-2-yl group Chemical group [H]C1=C([H])N=C(*)S1 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2467MUN2014 IN2014MN02467A (OSRAM) | 2012-06-08 | 2013-06-08 |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1687MU2012 | 2012-06-08 | ||
| US201261665282P | 2012-06-27 | 2012-06-27 | |
| IN3519MU2012 | 2012-12-13 | ||
| US201261748016P | 2012-12-31 | 2012-12-31 | |
| PCT/IB2013/054703 WO2013183035A2 (en) | 2012-06-08 | 2013-06-08 | Amides of 2-amino-4-arylthiazole compounds and their salts |
| IN2467MUN2014 IN2014MN02467A (OSRAM) | 2012-06-08 | 2013-06-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN02467A true IN2014MN02467A (OSRAM) | 2015-07-10 |
Family
ID=54193746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2467MUN2014 IN2014MN02467A (OSRAM) | 2012-06-08 | 2013-06-08 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9458173B2 (OSRAM) |
| EP (1) | EP2858999B1 (OSRAM) |
| JP (1) | JP5989900B2 (OSRAM) |
| KR (1) | KR20150015488A (OSRAM) |
| CN (1) | CN104350058A (OSRAM) |
| AP (1) | AP3546A (OSRAM) |
| AU (1) | AU2013273118B2 (OSRAM) |
| BR (1) | BR112014029155A2 (OSRAM) |
| CA (1) | CA2873570C (OSRAM) |
| CL (1) | CL2014003317A1 (OSRAM) |
| EA (1) | EA031334B1 (OSRAM) |
| HK (1) | HK1207643A1 (OSRAM) |
| IL (1) | IL236084A0 (OSRAM) |
| IN (1) | IN2014MN02467A (OSRAM) |
| MX (1) | MX354014B (OSRAM) |
| MY (1) | MY165622A (OSRAM) |
| NZ (1) | NZ701721A (OSRAM) |
| PE (1) | PE20142306A1 (OSRAM) |
| PH (1) | PH12014502685A1 (OSRAM) |
| SG (1) | SG11201408093PA (OSRAM) |
| WO (1) | WO2013183035A2 (OSRAM) |
| ZA (1) | ZA201500082B (OSRAM) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2014014766A (es) | 2012-06-08 | 2015-05-11 | Gilead Sciences Inc | Inhibidores macrociclicos de virus flaviviridae. |
| AR091279A1 (es) | 2012-06-08 | 2015-01-21 | Gilead Sciences Inc | Inhibidores macrociclicos de virus flaviviridae |
| MX2015016024A (es) | 2013-06-20 | 2016-04-04 | Glenmark Pharmaceuticals Sa | Formulacion en nanoparticulas que comprende un antagonista para trpa1. |
| EP3180345B1 (en) * | 2014-08-11 | 2018-10-10 | Hydra Biosciences, Inc. | Thieno- and furo[2,3-d]pyrimidine-2,4[1h,3h]-dione derivatives as trpc5 modulators for the treatment of neuropsychiatric disorders |
| WO2016042501A1 (en) * | 2014-09-16 | 2016-03-24 | Glenmark Pharmaceuticals S.A. | Trpa1 antagonist for the treatment of pain associated to diabetic neuropathic pain |
| TW202321229A (zh) | 2021-08-18 | 2023-06-01 | 美商富曼西公司 | 殺真菌的取代的雜環化合物 |
| CN114671875A (zh) * | 2022-04-27 | 2022-06-28 | 成都施贝康生物医药科技有限公司 | 新型二氢嘧啶类化合物、异构体或盐及其制备方法和用途 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2248231A1 (de) | 1972-10-02 | 1974-04-11 | Basf Ag | 3-aminoisothiazolo eckige klammer auf 3,4-d eckige klammer zu pyrimidine |
| SE9701398D0 (sv) | 1997-04-15 | 1997-04-15 | Astra Pharma Prod | Novel compounds |
| ES2193839B1 (es) * | 2001-06-22 | 2005-02-16 | Almirall Prodesfarma, S.A. | Nuevos derivados de 6-fenildihidropirrolpirimidindiona. |
| AU2003253165A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Pyrimidine fused bicyclic metalloproteinase inhibitors |
| US6890923B2 (en) | 2002-12-16 | 2005-05-10 | Astrazeneca Ab | Compounds |
| AU2003290066A1 (en) | 2002-12-18 | 2004-07-09 | Novartis Ag | Anktm1, a cold-activated trp-like channel expressed in nociceptive neurons |
| EP1657238A4 (en) | 2003-08-22 | 2008-12-03 | Takeda Pharmaceutical | CONDENSATE PYRIMIDINE DERIVATIVE AND ITS USE |
| JP2007522214A (ja) | 2004-02-11 | 2007-08-09 | スミスクライン・ビーチャム・コーポレイション | Ｐｔｈアゴニスト |
| WO2005089206A2 (en) | 2004-03-13 | 2005-09-29 | Irm Llc | Modulators of ion channel trpa1 |
| US20090062258A1 (en) | 2005-02-03 | 2009-03-05 | Takeda Pharmaceutical Company Limited | Fused pyrimidine derivative and use thereof |
| JP2009503107A (ja) | 2005-08-04 | 2009-01-29 | アポジー・バイオテクノロジー・コーポレイション | スフィンゴシンキナーゼ阻害剤およびそれらの使用方法 |
| US20070105920A1 (en) | 2005-11-08 | 2007-05-10 | Akzo Nobel N.V. | 2-(Benzimidazol-1-Yl)-N-(4-phenylthiazol-2-yl) acetamide derivatives |
| TW201900217A (zh) * | 2005-12-22 | 2019-01-01 | 美商海卓勒生物科學公司 | 用於調節ｔｒｐａ１功能之化合物 |
| CN101454318A (zh) * | 2006-03-22 | 2009-06-10 | 阿斯利康(瑞典)有限公司 | 吡啶并嘧啶衍生物及其作为pde4抑制剂的用途 |
| TW200800997A (en) | 2006-03-22 | 2008-01-01 | Astrazeneca Ab | Chemical compounds |
| JP2011201776A (ja) | 2008-07-23 | 2011-10-13 | Mochida Pharmaceut Co Ltd | ヘテロシクリデン−ｎ−（３，４−ジヒドロ−２（１ｈ）−キナゾリノン−５−イル）アセトアミド誘導体 |
| CL2008000252A1 (es) | 2007-01-29 | 2008-03-14 | Xenon Pharmaceuticals Inc | Compuestos derivados de quinazolinona o pirimidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar enfermedades mediadas por los canales de calcio, tales como dolor, depresion, enfermedades cardiovasculares, respir |
| SI3184527T1 (sl) * | 2007-06-22 | 2020-03-31 | Eli Lilly And Company | Spojine 2,6-diokso,-2,3-dihidro-1H-purina uporabne za zdravljenje stanj povezanih z aktivnostjo TRPA1 kanala |
| WO2010004390A1 (en) * | 2008-06-17 | 2010-01-14 | Glenmark Pharmaceuticals, S.A. | Quinazoline dione derivatives as trpa1 modulators |
| WO2009158719A2 (en) | 2008-06-27 | 2009-12-30 | Hydra Biosciences, Inc. | Methods and compositions for treating disorders |
| CN102361874A (zh) | 2009-03-23 | 2012-02-22 | 格兰马克药品股份有限公司 | 作为trpa1调节剂的呋喃并嘧啶二酮衍生物 |
| US8623880B2 (en) | 2009-03-23 | 2014-01-07 | Glenmark Pharmaceuticals S.A. | Fused pyrimidine-dione derivatives as TRPA1 modulators |
| SG184766A1 (en) | 2009-03-23 | 2012-10-30 | Glenmark Pharmaceuticals Sa | Isothiazolo-pyrimidinedione derivatives as trpa1 modulators |
| ES2551085T3 (es) | 2009-03-23 | 2015-11-16 | Glenmark Pharmaceuticals S.A. | Proceso para preparar derivados de pirimidina-diona condensados, útiles como moduladores de TRPA1 |
| MX336549B (es) | 2010-12-20 | 2016-01-22 | Glenmark Pharmaceuticals Sa | Compuestos de 2-amino-4-ariltiazol como antagonistas de trpa1. |
-
2013
- 2013-06-08 BR BR112014029155A patent/BR112014029155A2/pt not_active Application Discontinuation
- 2013-06-08 JP JP2015515642A patent/JP5989900B2/ja not_active Expired - Fee Related
- 2013-06-08 IN IN2467MUN2014 patent/IN2014MN02467A/en unknown
- 2013-06-08 MX MX2014014482A patent/MX354014B/es active IP Right Grant
- 2013-06-08 AU AU2013273118A patent/AU2013273118B2/en not_active Ceased
- 2013-06-08 US US14/402,608 patent/US9458173B2/en not_active Expired - Fee Related
- 2013-06-08 AP AP2014008076A patent/AP3546A/xx active
- 2013-06-08 CN CN201380030184.XA patent/CN104350058A/zh active Pending
- 2013-06-08 WO PCT/IB2013/054703 patent/WO2013183035A2/en not_active Ceased
- 2013-06-08 CA CA2873570A patent/CA2873570C/en active Active
- 2013-06-08 NZ NZ701721A patent/NZ701721A/en not_active IP Right Cessation
- 2013-06-08 EA EA201492054A patent/EA031334B1/ru unknown
- 2013-06-08 MY MYPI2014003389A patent/MY165622A/en unknown
- 2013-06-08 KR KR1020147033855A patent/KR20150015488A/ko not_active Abandoned
- 2013-06-08 SG SG11201408093PA patent/SG11201408093PA/en unknown
- 2013-06-08 HK HK15108333.2A patent/HK1207643A1/xx unknown
- 2013-06-08 PE PE2014002226A patent/PE20142306A1/es not_active Application Discontinuation
- 2013-06-08 EP EP13742279.6A patent/EP2858999B1/en active Active
-
2014
- 2014-12-02 PH PH12014502685A patent/PH12014502685A1/en unknown
- 2014-12-04 CL CL2014003317A patent/CL2014003317A1/es unknown
- 2014-12-04 IL IL236084A patent/IL236084A0/en unknown
-
2015
- 2015-01-07 ZA ZA2015/00082A patent/ZA201500082B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013183035A3 (en) | 2014-02-27 |
| EP2858999A2 (en) | 2015-04-15 |
| EP2858999B1 (en) | 2017-05-10 |
| US9458173B2 (en) | 2016-10-04 |
| AU2013273118B2 (en) | 2015-11-05 |
| HK1207643A1 (en) | 2016-02-05 |
| CL2014003317A1 (es) | 2015-02-13 |
| AP2014008076A0 (en) | 2014-11-30 |
| WO2013183035A2 (en) | 2013-12-12 |
| AU2013273118A1 (en) | 2014-11-27 |
| MY165622A (en) | 2018-04-18 |
| JP5989900B2 (ja) | 2016-09-07 |
| BR112014029155A2 (pt) | 2017-06-27 |
| EA201492054A1 (ru) | 2016-08-31 |
| CN104350058A (zh) | 2015-02-11 |
| CA2873570C (en) | 2016-11-01 |
| MX2014014482A (es) | 2015-06-05 |
| PH12014502685B1 (en) | 2015-01-26 |
| EA031334B1 (ru) | 2018-12-28 |
| SG11201408093PA (en) | 2015-01-29 |
| US20150111038A1 (en) | 2015-04-23 |
| AP3546A (en) | 2016-01-14 |
| CA2873570A1 (en) | 2013-12-12 |
| JP2015520183A (ja) | 2015-07-16 |
| MX354014B (es) | 2018-02-08 |
| PE20142306A1 (es) | 2015-01-16 |
| PH12014502685A1 (en) | 2015-01-26 |
| KR20150015488A (ko) | 2015-02-10 |
| NZ701721A (en) | 2016-03-31 |
| ZA201500082B (en) | 2015-12-23 |
| IL236084A0 (en) | 2015-02-01 |
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