PE20110330A1 - Composicion topica para el tratamiento de queratosis actinica - Google Patents

Composicion topica para el tratamiento de queratosis actinica

Info

Publication number
PE20110330A1
PE20110330A1 PE2010001215A PE2010001215A PE20110330A1 PE 20110330 A1 PE20110330 A1 PE 20110330A1 PE 2010001215 A PE2010001215 A PE 2010001215A PE 2010001215 A PE2010001215 A PE 2010001215A PE 20110330 A1 PE20110330 A1 PE 20110330A1
Authority
PE
Peru
Prior art keywords
weight
treatment
group
actinic keratosis
same
Prior art date
Application number
PE2010001215A
Other languages
English (en)
Inventor
Manfred Melzer
Carmen Matthies
Klaus Treudler
Christoph Willers
Henning Mallwitz
Original Assignee
Almirall Hermal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40039993&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20110330(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Almirall Hermal Gmbh filed Critical Almirall Hermal Gmbh
Publication of PE20110330A1 publication Critical patent/PE20110330A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/12Keratolytics, e.g. wart or anti-corn preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE REFIERE A UNA COMPOSICION DE GEL TOPICA QUE COMPRENDE A) UN AGENTE ACTIVO PARA EL TRATAMIENTO DE LA QUERATOSIS ACTINICA QUE COMPRENDE 0,25 Y 4,5% EN PESO SELECCIONADO DEL GRUPO DE INHIBIDORES DE CICLOOXIGENASA, MODULADORES INMUNOLOGICOS TOPICOS, ANTIMETABOLITOS Y MEZCLAS DE LO MISMOS; B) UN AGENTE QUERATOLITICAMENTE ACTIVO QUE COMPRENDE ENTRE 0,025 Y 30% EN PESO SELECCIONADO ENTRE AGONISTAS DEL RECEPTOR RETINOIDE, UREA, ACIDOS ORGANICOS TALES COMO ACIDO GLICOLICO, ACIDO SALICILICO, ACIDO LACTICO, ENTRE OTROS, Y MEZCLAS DE LOS MISMOS; C) UN FORMADOR DE GEL QUE COMPRENDE ENTRE 1 Y 30% EN PESO SELECCIONADO DE HOMOPOLIMEROS Y COPOLIMEROS DE VINILO, DERIVADOS DE CELULOSA Y MEZCLAS DE LOS MISMOS; D) UN SOVENTE ORGANICO QUE COMPRENDE ENTRE 1 Y 90% EN PESO SELECCIONADO DEL GRUPO DE ALCOHOLES C1-C10, ESTERES DE ALCOHOLES C1-C10 CON ACIDOS CARBOXILICOS C1-C10 Y MEZCLAS DE LOS MISMOS. ADEMAS PUEDE CONTENER UN MEJORADOR DE PENETRACION DE LA PIEL SELECCIONADO DEL GRUPO DE ALCOHOLES POLIVALENTES ALIFATICOS C2-C10, POLIALQUILENGLICOLES, ETERES NO ALCOXILADOS, ENTRE OTROS. DICHA COMPOSICION COMPRENDE MENOS QUE UN 5% EN PESO DE AGUA, TIENE UNA VISCOSIDAD ENTRE 300 A 1500 mPas A 20ºC, UTIL EN EL TRATAMIENTO DE QUERATOSIS ACTINICA
PE2010001215A 2008-07-07 2009-06-29 Composicion topica para el tratamiento de queratosis actinica PE20110330A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08012237A EP2143421A1 (en) 2008-07-07 2008-07-07 Topical composition for the treatment of actinic keratosis

Publications (1)

Publication Number Publication Date
PE20110330A1 true PE20110330A1 (es) 2011-06-11

Family

ID=40039993

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2010001215A PE20110330A1 (es) 2008-07-07 2009-06-29 Composicion topica para el tratamiento de queratosis actinica

Country Status (32)

Country Link
US (1) US8569320B2 (es)
EP (2) EP2143421A1 (es)
JP (2) JP5654987B2 (es)
KR (1) KR101689898B1 (es)
CN (2) CN104825384A (es)
AR (1) AR072685A1 (es)
AU (1) AU2009267471B2 (es)
BR (1) BRPI0915439B8 (es)
CA (1) CA2729974A1 (es)
CL (1) CL2010001642A1 (es)
CO (1) CO6351710A2 (es)
CY (1) CY1116111T1 (es)
DK (1) DK2315581T3 (es)
EA (1) EA019533B1 (es)
EC (1) ECSP11010762A (es)
ES (1) ES2532948T3 (es)
HK (1) HK1154793A1 (es)
HR (1) HRP20150222T1 (es)
IL (1) IL210134A (es)
ME (1) ME02147B (es)
MX (1) MX2011000054A (es)
MY (1) MY158428A (es)
NZ (1) NZ590288A (es)
PE (1) PE20110330A1 (es)
PL (1) PL2315581T3 (es)
PT (1) PT2315581E (es)
RS (1) RS53887B1 (es)
SI (1) SI2315581T1 (es)
TW (1) TWI433692B (es)
UA (1) UA101044C2 (es)
WO (1) WO2010003568A1 (es)
ZA (1) ZA201100653B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5798561B2 (ja) * 2009-10-08 2015-10-21 エムエスディー コンシューマー ケア, インコーポレイテッド 低エーテル組成物およびデリバリー装置
JP5950528B2 (ja) * 2011-09-30 2016-07-13 小林製薬株式会社 皮膜形成性外用製剤
WO2013088375A1 (en) * 2011-12-12 2013-06-20 Leo Laboratories Limited A topical composition comprising an ingenol derivative and an oily solvent
NZ606177A (en) * 2012-01-30 2014-03-28 Dolorgiet Gmbh & Co Kg Compositions for the treatment of actinic keratosis
GB201222405D0 (en) * 2012-12-12 2013-01-23 Leo Lab Ltd Gel compositions
JP2017521470A (ja) * 2014-07-31 2017-08-03 サン ファーマシューティカル インダストリーズ リミテッドSun Pharmaceutical Industries Ltd. イソトレチノインの経口医薬組成物
MX2017003251A (es) 2014-09-12 2017-12-20 Antibiotx Aps Uso antibacteriano de salicilanilidas halogenadas.
GB201509326D0 (en) 2015-05-29 2015-07-15 Antibio Tx Aps Novel use
JP6659735B2 (ja) * 2015-07-10 2020-03-04 インフェクトファーム・アルツナイミッテル・ウント・コンシリウム・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 日光角化症の治療における水酸化カリウムの使用
GB201604484D0 (en) 2016-03-16 2016-04-27 Antibiotx Aps And Københavns Uni University Of Copenhagen Topical antibacterial compositions
CA3055938A1 (en) 2017-03-10 2018-09-13 Athenex, Inc. Methods of treating and/or preventing actinic keratosis
US11419834B2 (en) 2019-02-25 2022-08-23 Rhode Island Hospital Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide
US20220175769A1 (en) * 2020-12-08 2022-06-09 Ankh Life Sciences Limited Method of treatment of actinic keratoses
DK202370132A1 (en) * 2023-03-14 2024-10-10 Repoceuticals Aps Compositions for use in the treatment of actinic keratosis

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2802005A (en) 1957-08-06 S-eluorourace
US4234599A (en) * 1978-10-04 1980-11-18 Scott Eugene J Van Treatment of skin keratoses with α-hydroxy acids and related compounds
US5091171B2 (en) * 1986-12-23 1997-07-15 Tristrata Inc Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use
US5167649A (en) * 1988-08-22 1992-12-01 Zook Gerald P Drug delivery system for the removal of dermal lesions
US5093360A (en) * 1989-04-07 1992-03-03 Yu Ruey J Retinal, derivatives and their therapeutic use
GB9023701D0 (en) * 1990-10-31 1990-12-12 Efamol Holdings Medical treatment
JP3117502B2 (ja) * 1991-08-27 2000-12-18 株式会社資生堂 皮膚外用剤
US5627187A (en) 1995-04-12 1997-05-06 Katz; Bruce E. 5-FU for treating actinic kerotoses
KR20000022054A (ko) * 1996-06-20 2000-04-25 아타나스 라비다스 여드름의 국소 치료 제형 및 이의 제조방법
US5993787A (en) * 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations
US5955097A (en) * 1996-10-18 1999-09-21 Virotex Corporation Pharmaceutical preparation applicable to mucosal surfaces and body tissues
US6462071B1 (en) * 2000-03-02 2002-10-08 Vitreo-Retinal Technologies, Inc. Agents for intravitreal administration to treat or prevent disorders of the eye
ES2223277B1 (es) * 2003-06-19 2006-03-01 Fernando Bouffard Fita Composicion anestesica para administracion topica.
MXPA06002163A (es) * 2003-08-25 2006-05-22 Foamix Ltd Espuma farmaceutica de penetracion.
US20050137164A1 (en) * 2003-09-22 2005-06-23 Moshe Arkin Diclofenac compositions for the treatment of skin disorders
JP5324091B2 (ja) * 2004-06-24 2013-10-23 アイデックス ラボラトリーズ,インコーポレイティド 薬物送達のための医薬組成物及びそれを使用する症状の治療又は予防法
US20070053984A1 (en) 2005-03-03 2007-03-08 Monique Spann-Wade Topical gels compositions
WO2006134406A1 (en) * 2005-06-14 2006-12-21 Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. Stable pharmaceutical gel of diclofenac sodium
US7851431B2 (en) * 2005-07-27 2010-12-14 Prescription Dispensing Laboratories Treatment of actinic keratoses with calcium channel blockers
US20070264317A1 (en) * 2006-05-15 2007-11-15 Perrigo Israel Pharmaceuticals Ltd. Imiquimod cream formulation
WO2008047857A1 (fr) * 2006-10-18 2008-04-24 Fujifilm Corporation Procédé de production d'une composition comprenant un composé difficilement soluble dans l'eau incorporé dans une matrice hydrophile et préparation pour une utilisation externe comprenant un agent ou médicament anticancéreux ayant un coefficient de partage octanol/eau (log p) de -3,0 ou plus mais pas plus de 3,0, incorporé

Also Published As

Publication number Publication date
CY1116111T1 (el) 2017-02-08
CN104825384A (zh) 2015-08-12
BRPI0915439B1 (pt) 2019-10-08
EP2143421A1 (en) 2010-01-13
ZA201100653B (en) 2011-10-26
EA201100020A1 (ru) 2011-06-30
US20110301130A1 (en) 2011-12-08
ECSP11010762A (es) 2012-03-30
RS53887B1 (en) 2015-08-31
US8569320B2 (en) 2013-10-29
MX2011000054A (es) 2011-11-04
CO6351710A2 (es) 2011-12-20
PT2315581E (pt) 2015-04-02
JP5654987B2 (ja) 2015-01-14
JP2015038129A (ja) 2015-02-26
NZ590288A (en) 2012-08-31
HRP20150222T1 (hr) 2015-05-22
TW201006507A (en) 2010-02-16
AU2009267471B2 (en) 2014-06-05
AR072685A1 (es) 2010-09-15
IL210134A (en) 2015-06-30
MY158428A (en) 2016-10-14
CA2729974A1 (en) 2010-01-14
SI2315581T1 (sl) 2015-05-29
KR20110027838A (ko) 2011-03-16
ME02147B (me) 2015-10-20
EP2315581A1 (en) 2011-05-04
IL210134A0 (en) 2011-02-28
BRPI0915439A2 (pt) 2015-11-10
CL2010001642A1 (es) 2011-04-08
EP2315581B1 (en) 2014-12-17
WO2010003568A1 (en) 2010-01-14
ES2532948T3 (es) 2015-04-06
UA101044C2 (ru) 2013-02-25
KR101689898B1 (ko) 2016-12-26
AU2009267471A1 (en) 2010-01-14
BRPI0915439B8 (pt) 2021-05-25
EA019533B1 (ru) 2014-04-30
DK2315581T3 (en) 2015-03-23
HK1154793A1 (en) 2012-05-04
PL2315581T3 (pl) 2015-06-30
WO2010003568A8 (en) 2011-02-03
JP2011526934A (ja) 2011-10-20
CN102088957A (zh) 2011-06-08
TWI433692B (zh) 2014-04-11

Similar Documents

Publication Publication Date Title
PE20110330A1 (es) Composicion topica para el tratamiento de queratosis actinica
PE20140936A1 (es) Composiciones transdermicas de ibuprofeno y metodos de uso de las mismas
BR112015019657A2 (pt) composições tópicas e métodos de uso das mesmas
ES2580635T3 (es) Composición cosmética que comprende un agente estructurante, un agente absorbente y un agente tensioactivo para la aplicación a las materias queratínicas
CY1120888T1 (el) Διαδερμικες φαρμακευτικες συνθεσεις περιλαμβανοντας ενεργους παραγοντες
BR112013018352A2 (pt) composição de minociclina tópica e método
CL2015001984A1 (es) (divisional de la sol. 1567-2013) combinaciones de principios activos que comprenden piridiletilbenzamidas y otros principios activos.
CL2009000245A1 (es) Compuestos derivados de heterociclil piridinilo, con actividad moduladora del receptor 5-ht6; composicion farmaceutica que los comprende y su uso para tratar la esquizofrenia, ansiedad, migrana, depresion, entre otros.
MX2018011881A (es) Sistema de administracion.
PE20191815A1 (es) Formulaciones acuosas estables de adalimumab
PE20091363A1 (es) Gel de quitosano y proceso de obtencion
ES2543957T3 (es) Nueva composición farmacéutica para el tratamiento de infecciones fúngicas
BR112014016550A2 (pt) formulação de liberação retardada para reduzir a frequência de urinação e método de uso da mesma
AR067751A1 (es) Composicion veterinaria topica, proceso para la preparacion de una composicion y metodo para el tratamiento de infeccion endoparasitaria o infestacion en un animal homeotermico
PE20121709A1 (es) Una composicion farmaceutica para tratar cancer que comprende tripsinogeno y/o quimotripsinogeno y un agente activo seleccionado a partir de un compuesto de selenio, un compuesto vainilloide y un agente reductor de glicolisis citoplasmica
BR112014016661A8 (pt) formulação de liberação prolongada para reduzir a frequência de urinação e método de uso da mesma
JP2015512926A5 (es)
PE20170691A1 (es) Composiciones farmaceuticas de accion prolongada
BR112013004455A2 (pt) composições para fornecimento gástrico de agentes ativos
AR083651A1 (es) Composiciones de brimonidina en gel y metodos de uso
MX359713B (es) Composiciones mejoradas para la cicatrizacion de heridas que comprenden microesferas.
NI201500007A (es) Formulación transdérmica que contiene inhibidores de cox
PE20151300A1 (es) Composicion antifungica topica para el tratamiento de onicomicosis
PE20160198A1 (es) Composiciones topicas para el tratamiento de sudoracion excesiva y metodos para utilizar las mismas
MX2019002921A (es) Composiciones para el cuidado bucal y sistema para dispensar las mismas.

Legal Events

Date Code Title Description
FD Application declared void or lapsed