PE20070457A1 - Composicion que comprende un inhibidor del receptor del factor de crecimiento endotelial vascular - Google Patents
Composicion que comprende un inhibidor del receptor del factor de crecimiento endotelial vascularInfo
- Publication number
- PE20070457A1 PE20070457A1 PE2006001109A PE2006001109A PE20070457A1 PE 20070457 A1 PE20070457 A1 PE 20070457A1 PE 2006001109 A PE2006001109 A PE 2006001109A PE 2006001109 A PE2006001109 A PE 2006001109A PE 20070457 A1 PE20070457 A1 PE 20070457A1
- Authority
- PE
- Peru
- Prior art keywords
- receptor
- growth factor
- substituted
- nitro
- halogen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: A) COMPUESTOS INHIBIDORES DEL RECEPTOR DEL FACTOR DE CRECIMIENTO ENDOTELIAL VASCULAR DE FORMULA (I) DONDE R1 ES H, HALOGENO, (C0-C7)-R3, ENTRE OTROS, DONDE R3 ES H O ALQUILO(C1-C4) OPCIONALMENTE SUSTITUIDO CON AMINO, OH, CN, NITRO, ENTRE OTROS; R2 ES CICLOALQUILO(C3-C8) SUSTITUIDO CON CN, NITRO, CARBOXILO, ENTRE OTROS SUSTITUYENTES, ARILO SUSTITUIDO CON CN, UREIDO, HALOGENO, ENTRE OTROS SUSTITUYENTES, O HETEROCICLILO SUSTITUIDO CON CN, NITRO, GUANIDINO, ENTR E OTROS; A, B Y X SON =C(R7)- O N; E, G Y T SON =C(R8)- O N, DONDE R7 Y R8 SON CADA UNO H, HALOGENO O ALQUILO(C1-C4) OPCIONALMENTE SUSTITUIDO CON AMINO, OH, CN, NITRO, ENTRE OTROS; Y ES O, S, S(O), S(O)2, ENTRE OTROS; Z ES CH, N O C; Q ES ALQUILENO(C1-C4) O ALQUENILENO(C2-C4); ---- ES UN ENLACE SIMPLE O DOBLE; W ESTA AUSENTE, ES ALQUILENO(C1-C3), ENTRE OTROS; SIENDO PREFERIDO UN COMPUESTO DE FORMULA (i); Y B) UN POTENCIADOR DE ABSORCION TAL COMO ACIDOS GRASOS INSATURADOS, ESTERES DE ACIDOS GRASOS INSATURADOS, ENTRE OTROS. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE PSORIASIS, DERMATITIS ATOPICA, ACNE
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0518672A GB0518672D0 (en) | 2005-09-13 | 2005-09-13 | Organic compounds |
GB0518671A GB0518671D0 (en) | 2005-09-13 | 2005-09-13 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20070457A1 true PE20070457A1 (es) | 2007-06-06 |
Family
ID=37663150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2006001109A PE20070457A1 (es) | 2005-09-13 | 2006-09-12 | Composicion que comprende un inhibidor del receptor del factor de crecimiento endotelial vascular |
Country Status (23)
Country | Link |
---|---|
US (2) | US20080306058A1 (es) |
EP (1) | EP1945217B1 (es) |
JP (1) | JP2009507871A (es) |
KR (1) | KR20080058376A (es) |
AR (1) | AR056194A1 (es) |
AT (1) | ATE555790T1 (es) |
AU (1) | AU2006291526B2 (es) |
BR (1) | BRPI0615881A2 (es) |
CA (1) | CA2621399A1 (es) |
EC (1) | ECSP088259A (es) |
GT (1) | GT200600411A (es) |
IL (1) | IL189984A0 (es) |
MA (1) | MA29788B1 (es) |
MY (1) | MY145751A (es) |
NO (1) | NO20081807L (es) |
NZ (1) | NZ566474A (es) |
PE (1) | PE20070457A1 (es) |
RU (1) | RU2424804C2 (es) |
SA (1) | SA06270315B1 (es) |
SG (1) | SG165371A1 (es) |
TN (1) | TNSN08112A1 (es) |
TW (1) | TWI325321B (es) |
WO (1) | WO2007031265A2 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0605120D0 (en) | 2006-03-14 | 2006-04-26 | Novartis Ag | Organic Compounds |
CN101687801B (zh) | 2007-04-17 | 2012-10-03 | 诺瓦提斯公司 | 用作癌症治疗的萘甲酸酰胺的醚 |
WO2009026408A1 (en) * | 2007-08-22 | 2009-02-26 | Allergan, Inc. | Therapeutic quinoline and naphthalene derivatives |
JO3265B1 (ar) | 2008-12-09 | 2018-09-16 | Novartis Ag | مثبطات بيريديلوكسى اندولات vegf-r2 واستخدامها لعلاج المرض |
US20110112121A1 (en) | 2009-07-06 | 2011-05-12 | Joerg Berghausen | Pharmaceutical Compositions and Solid Forms |
WO2012094451A1 (en) * | 2011-01-06 | 2012-07-12 | Beta Pharma Canada Inc. | Novel ureas for the treatment and prevention of cancer |
EP2786752B1 (en) * | 2011-12-01 | 2019-06-12 | Teikoku Seiyaku Co., Ltd. | Ropinirole-containing adhesive patch |
US10149834B2 (en) | 2011-12-01 | 2018-12-11 | Teikoku Seiyaku Co., Ltd. | Ropinirole-containing adhesive patch |
CN104334543B (zh) * | 2013-04-09 | 2017-08-25 | 广州慧柏瑞生物医药科技有限公司 | 抗新生血管的化合物、其中间体及其用途 |
CN106414402A (zh) * | 2013-11-01 | 2017-02-15 | 宇部兴产株式会社 | 丙烯酰(氧基或氨基)五氟硫烷基苯化合物、其药学可接受的盐及其前药 |
CN104860885B (zh) * | 2014-02-24 | 2017-11-17 | 中国科学院上海药物研究所 | 萘酰胺类化合物、其制备方法和用途 |
JO3705B1 (ar) * | 2014-11-26 | 2021-01-31 | Bayer Pharma AG | إندازولات مستبدلة جديدة، عمليات لتحضيرها، مستحضرات دوائية تحتوي عليها واستخدامها في إنتاج أدوية |
CN107098884A (zh) * | 2016-02-19 | 2017-08-29 | 中国科学院上海药物研究所 | 一类取代的氨基吡啶类化合物及其制备和用途 |
JP2023515630A (ja) * | 2020-02-28 | 2023-04-13 | 上▲海▼▲潤▼石医▲薬▼科技有限公司 | Csf-1rキナーゼ阻害剤の使用 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0148748B1 (ko) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
US5879690A (en) * | 1995-09-07 | 1999-03-09 | Perricone; Nicholas V. | Topical administration of catecholamines and related compounds to subcutaneous muscle tissue using percutaneous penetration enhancers |
US6355657B1 (en) * | 1998-12-30 | 2002-03-12 | Atrix Laboratories, Inc. | System for percutaneous delivery of opioid analgesics |
EP1212318B1 (de) * | 1999-08-27 | 2006-01-25 | Boehringer Ingelheim Pharma GmbH & Co.KG | Substituierte indolinone als tyrosinkinase inhibitoren |
ATE415396T1 (de) * | 2000-09-20 | 2008-12-15 | Ortho Mcneil Pharm Inc | Pyrazine derivate als tyrosin kinase modulatoren |
ATE399766T1 (de) * | 2000-10-20 | 2008-07-15 | Eisai R&D Man Co Ltd | Stickstoff enthaltende aromatische heterozyklen |
SI1478358T1 (sl) * | 2002-02-11 | 2013-09-30 | Bayer Healthcare Llc | Sorafenib tozilat za zdravljenje bolezni, značilnih po abnormalni angiogenezi |
BR0311172A (pt) * | 2002-05-13 | 2005-04-26 | Children S Hospital Los Angele | Tratamento e prevenção de formação de cicatriz anormal em quelóides e outras lesões ou ferimentos internos ou cutâneos |
PE20040522A1 (es) | 2002-05-29 | 2004-09-28 | Novartis Ag | Derivados de diarilurea dependientes de la cinasa de proteina |
EP1522540A4 (en) * | 2002-08-30 | 2011-08-10 | Eisai R&D Man Co Ltd | AZAARENE DERIVATIVES |
WO2004103159A2 (en) * | 2003-05-14 | 2004-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for modulating endometrium |
BRPI0414011A (pt) * | 2003-08-29 | 2006-10-24 | Pfizer | naftalencarboxamidas e seus derivados úteis como novos agentes antiangiogênicos |
WO2005069906A2 (en) * | 2004-01-16 | 2005-08-04 | Yale University | Methods and compositions relating to vascular endothelial growth factor and th2 mediated inflammatory diseases |
AU2005206571B8 (en) * | 2004-01-23 | 2010-09-02 | Amgen Inc. | Compounds and methods of use |
EP1568368A1 (en) * | 2004-02-26 | 2005-08-31 | Schering Aktiengesellschaft | Pharmaceutical combination comprising a CDK inhibitor and a VEGF receptor inhibitor |
PE20060664A1 (es) * | 2004-09-15 | 2006-08-04 | Novartis Ag | Amidas biciclicas como inhibidores de cinasa |
-
2006
- 2006-09-08 GT GT200600411A patent/GT200600411A/es unknown
- 2006-09-10 SA SA6270315A patent/SA06270315B1/ar unknown
- 2006-09-11 AR ARP060103941A patent/AR056194A1/es not_active Application Discontinuation
- 2006-09-12 SG SG201006609-0A patent/SG165371A1/en unknown
- 2006-09-12 TW TW095133706A patent/TWI325321B/zh not_active IP Right Cessation
- 2006-09-12 RU RU2008114048/15A patent/RU2424804C2/ru not_active IP Right Cessation
- 2006-09-12 KR KR1020087008666A patent/KR20080058376A/ko not_active Application Discontinuation
- 2006-09-12 EP EP06791989A patent/EP1945217B1/en not_active Not-in-force
- 2006-09-12 NZ NZ566474A patent/NZ566474A/en not_active IP Right Cessation
- 2006-09-12 CA CA002621399A patent/CA2621399A1/en not_active Abandoned
- 2006-09-12 AU AU2006291526A patent/AU2006291526B2/en not_active Ceased
- 2006-09-12 AT AT06791989T patent/ATE555790T1/de active
- 2006-09-12 PE PE2006001109A patent/PE20070457A1/es not_active Application Discontinuation
- 2006-09-12 JP JP2008530401A patent/JP2009507871A/ja active Pending
- 2006-09-12 MY MYPI20080558A patent/MY145751A/en unknown
- 2006-09-12 BR BRPI0615881-1A patent/BRPI0615881A2/pt not_active IP Right Cessation
- 2006-09-12 US US12/066,726 patent/US20080306058A1/en not_active Abandoned
- 2006-09-12 WO PCT/EP2006/008857 patent/WO2007031265A2/en active Application Filing
-
2008
- 2008-03-06 IL IL189984A patent/IL189984A0/en unknown
- 2008-03-11 EC EC2008008259A patent/ECSP088259A/es unknown
- 2008-03-12 TN TNP2008000112A patent/TNSN08112A1/en unknown
- 2008-03-17 MA MA30759A patent/MA29788B1/fr unknown
- 2008-04-14 NO NO20081807A patent/NO20081807L/no not_active Application Discontinuation
-
2012
- 2012-03-15 US US13/420,993 patent/US20120172386A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1945217A2 (en) | 2008-07-23 |
AU2006291526B2 (en) | 2010-07-29 |
NO20081807L (no) | 2008-05-16 |
RU2424804C2 (ru) | 2011-07-27 |
CA2621399A1 (en) | 2007-03-22 |
MY145751A (en) | 2012-03-30 |
SG165371A1 (en) | 2010-10-28 |
TNSN08112A1 (en) | 2009-07-14 |
AU2006291526A1 (en) | 2007-03-22 |
WO2007031265A2 (en) | 2007-03-22 |
IL189984A0 (en) | 2008-11-03 |
TWI325321B (en) | 2010-06-01 |
RU2008114048A (ru) | 2009-10-20 |
ECSP088259A (es) | 2008-04-28 |
NZ566474A (en) | 2011-05-27 |
JP2009507871A (ja) | 2009-02-26 |
US20120172386A1 (en) | 2012-07-05 |
KR20080058376A (ko) | 2008-06-25 |
SA06270315B1 (ar) | 2010-12-21 |
TW200744600A (en) | 2007-12-16 |
MA29788B1 (fr) | 2008-09-01 |
US20080306058A1 (en) | 2008-12-11 |
EP1945217B1 (en) | 2012-05-02 |
ATE555790T1 (de) | 2012-05-15 |
BRPI0615881A2 (pt) | 2011-05-31 |
GT200600411A (es) | 2007-05-21 |
WO2007031265A3 (en) | 2007-07-12 |
AR056194A1 (es) | 2007-09-26 |
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