AR082428A1 - Uso de un compuesto agonista de ep4 para preparar una composicion farmaceutica util para tratar una imperfeccion de la piel y metodos para reparar la piel relacionados - Google Patents
Uso de un compuesto agonista de ep4 para preparar una composicion farmaceutica util para tratar una imperfeccion de la piel y metodos para reparar la piel relacionadosInfo
- Publication number
- AR082428A1 AR082428A1 ARP110102761A ARP110102761A AR082428A1 AR 082428 A1 AR082428 A1 AR 082428A1 AR P110102761 A ARP110102761 A AR P110102761A AR P110102761 A ARP110102761 A AR P110102761A AR 082428 A1 AR082428 A1 AR 082428A1
- Authority
- AR
- Argentina
- Prior art keywords
- skin
- prepare
- pharmaceutical composition
- imperfection
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/91—Injection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Uso de un compuesto agonista de EP4 que tiene una estructura de fórmula (1) donde cada línea de puntos representa la presencia o ausencia de una unión doble; R1, R2, R3 y R4 están cada una independientemente seleccionadas de H y alquilo lineal C1-6; R5 es halógeno, alquilo C1-6, o alquenilo C1-6; R6 es H, alquilo C1-6, alquenilo C1-6, una sal de las mismas, o una amina de la misma; n es 0 - 7; y X es S u O, para preparar una composición farmacéutica útil para tratar una imperfección de la piel, tales como heridas, cicatrices y arrugas. Métodos para reparar la piel relacionados.Reivindicación 2: El uso de la reivindicación 1, caracterizado porque R4 es H, R3 es H, y X es S. Reivindicación 3: El uso de la reivindicación 1, caracterizado porque R1 y R2 son CH3. Reivindicación 4: El uso de la reivindicación 1, caracterizado porque R5 es Cl.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36923210P | 2010-07-30 | 2010-07-30 | |
US41911510P | 2010-12-02 | 2010-12-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR082428A1 true AR082428A1 (es) | 2012-12-05 |
Family
ID=44543791
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP110102761A AR082428A1 (es) | 2010-07-30 | 2011-07-29 | Uso de un compuesto agonista de ep4 para preparar una composicion farmaceutica util para tratar una imperfeccion de la piel y metodos para reparar la piel relacionados |
Country Status (17)
Country | Link |
---|---|
US (1) | US20120136011A1 (es) |
EP (1) | EP2598140B1 (es) |
JP (1) | JP2013536183A (es) |
KR (1) | KR20130130694A (es) |
CN (1) | CN103068382A (es) |
AR (1) | AR082428A1 (es) |
AU (1) | AU2011282549A1 (es) |
BR (1) | BR112013002319A2 (es) |
CA (1) | CA2806982A1 (es) |
CL (1) | CL2013000308A1 (es) |
CO (1) | CO6680670A2 (es) |
MX (1) | MX2013001227A (es) |
NZ (1) | NZ607306A (es) |
RU (1) | RU2013108394A (es) |
SG (1) | SG187653A1 (es) |
TW (1) | TW201210601A (es) |
WO (1) | WO2012016109A2 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8697458B2 (en) | 2009-04-22 | 2014-04-15 | Shat-R-Shield, Inc. | Silicone coated light-emitting diode |
US8883139B2 (en) * | 2010-08-19 | 2014-11-11 | Allergan Inc. | Compositions and soft tissue replacement methods |
US8926963B2 (en) * | 2010-08-19 | 2015-01-06 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US9005605B2 (en) * | 2010-08-19 | 2015-04-14 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US8889123B2 (en) * | 2010-08-19 | 2014-11-18 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US8741281B2 (en) * | 2010-08-19 | 2014-06-03 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US8697057B2 (en) * | 2010-08-19 | 2014-04-15 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US8900571B2 (en) * | 2010-08-19 | 2014-12-02 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US8894992B2 (en) * | 2010-08-19 | 2014-11-25 | Allergan, Inc. | Compositions and soft tissue replacement methods |
WO2012024072A1 (en) * | 2010-08-19 | 2012-02-23 | Allergan, Inc. | Compositions comprising adipose tissue and a pge2 analogue and their use in the treatment of a soft tissue condition |
US20120142684A1 (en) * | 2010-12-02 | 2012-06-07 | Allergan, Inc. | Compounds and methods for skin repair |
US20140142042A1 (en) * | 2012-11-16 | 2014-05-22 | Allergan, Inc. | Skin wound healing and scar reduction with prostaglandin ep4 agonist combinations |
WO2014078434A1 (en) * | 2012-11-16 | 2014-05-22 | Allergan, Inc. | Compounds and methods for skin repair |
US9546162B2 (en) * | 2013-09-27 | 2017-01-17 | Allergan, Inc. | Compounds and methods for skin repair |
RU2625548C1 (ru) * | 2015-04-29 | 2017-07-14 | Жанна Юрьевна Юсова | Способ коррекции возрастных изменений кожи лица |
TWI593403B (zh) * | 2016-12-01 | 2017-08-01 | yi-ting Xu | Remedial repair of facial damage |
RU2663391C1 (ru) * | 2018-01-30 | 2018-08-03 | Игорь Николаевич Бондаренко | Способ эстетической коррекции мягких тканей лица |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5811446A (en) * | 1997-04-18 | 1998-09-22 | Cytos Pharmaceuticals Llc | Prophylactic and therapeutic methods for ocular degenerative diseases and inflammations and histidine compositions therefor |
TWI249520B (en) * | 1998-07-15 | 2006-02-21 | Ono Pharmaceutical Co | 5-Thia-omega-substituted phenyl prostaglandin E derivatives, method for producing the same and medicines containing the same as the active ingredient |
US6586468B1 (en) * | 1998-09-14 | 2003-07-01 | Ono Pharmaceutical Co., Ltd. | ω-substituted phenyl-prostaglandin E derivatives and drugs containing the same as the active ingredient |
JP4618548B2 (ja) * | 1999-11-24 | 2011-01-26 | 小野薬品工業株式会社 | 骨量低下疾患治療剤 |
WO2003009872A1 (en) * | 2001-07-23 | 2003-02-06 | Ono Pharmaceutical Co., Ltd. | Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient |
US20040058313A1 (en) * | 2002-04-24 | 2004-03-25 | Abreu Marcio Marc | Compositions, targets, methods and devices for the therapy of ocular and periocular disorders |
TW200413000A (en) * | 2002-10-10 | 2004-08-01 | Ono Pharmaceutical Co | Intrinsic repair factor producing accelerator |
RU2336081C2 (ru) * | 2003-02-11 | 2008-10-20 | Аллерган, Инк. | Производные 10,10-диалкилпростановой кислоты для снижения внутриглазного давления |
US7855226B2 (en) * | 2003-02-11 | 2010-12-21 | Allergan, Inc. | Treatment of inflammatory bowel disease |
US6875787B2 (en) | 2003-02-11 | 2005-04-05 | Allergan, Inc. | 10,10-dialkyl prostanoic acid derivatives as agents for lowering intraocular pressure |
US20080234337A1 (en) * | 2004-08-10 | 2008-09-25 | Ono Pharmaceutical Co., Ltd. | Preventive and/or Remedy for Hyperkalemia Containing Ep4 Agonist |
JP2006321737A (ja) * | 2005-05-18 | 2006-11-30 | Ono Pharmaceut Co Ltd | Ep4アゴニストを含有する神経変性疾患の予防、治療および/または進展抑制剤 |
JP2007023028A (ja) * | 2005-06-16 | 2007-02-01 | Ono Pharmaceut Co Ltd | 内耳疾患治療剤 |
US20070232660A1 (en) * | 2006-04-04 | 2007-10-04 | Allergan, Inc. | Therapeutic and delivery methods of prostaglandin ep4 agonists |
US7439372B2 (en) * | 2006-05-03 | 2008-10-21 | Allergan, Inc. | Therapeutic compounds |
CA2672631A1 (en) * | 2006-12-15 | 2008-06-19 | Glaxo Group Limited | Benzamide derivatives as ep4 receptor agonists |
CA2690273A1 (en) * | 2006-12-18 | 2008-06-26 | Allergan, Inc. | Use of prostaglandin ep4 agonist for treating gastrointestinal disorders |
WO2008136519A1 (ja) * | 2007-05-08 | 2008-11-13 | National University Corporation, Hamamatsu University School Of Medicine | Ep4アゴニストを含有してなる細胞傷害性t細胞の活性化剤 |
GB0810615D0 (en) * | 2008-06-10 | 2008-07-16 | Glaxo Group Ltd | Novel pharmaceutical |
-
2011
- 2011-07-29 AU AU2011282549A patent/AU2011282549A1/en not_active Abandoned
- 2011-07-29 NZ NZ60730611A patent/NZ607306A/en unknown
- 2011-07-29 US US13/194,078 patent/US20120136011A1/en not_active Abandoned
- 2011-07-29 JP JP2013523219A patent/JP2013536183A/ja active Pending
- 2011-07-29 SG SG2013007430A patent/SG187653A1/en unknown
- 2011-07-29 CA CA2806982A patent/CA2806982A1/en not_active Abandoned
- 2011-07-29 MX MX2013001227A patent/MX2013001227A/es not_active Application Discontinuation
- 2011-07-29 TW TW100127126A patent/TW201210601A/zh unknown
- 2011-07-29 WO PCT/US2011/045833 patent/WO2012016109A2/en active Application Filing
- 2011-07-29 AR ARP110102761A patent/AR082428A1/es unknown
- 2011-07-29 EP EP11744157.6A patent/EP2598140B1/en active Active
- 2011-07-29 RU RU2013108394/15A patent/RU2013108394A/ru not_active Application Discontinuation
- 2011-07-29 KR KR1020137004837A patent/KR20130130694A/ko not_active Application Discontinuation
- 2011-07-29 CN CN2011800404387A patent/CN103068382A/zh active Pending
- 2011-07-29 BR BR112013002319A patent/BR112013002319A2/pt not_active IP Right Cessation
-
2013
- 2013-01-30 CL CL2013000308A patent/CL2013000308A1/es unknown
- 2013-02-26 CO CO13038986A patent/CO6680670A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2012016109A3 (en) | 2012-03-22 |
RU2013108394A (ru) | 2014-09-10 |
KR20130130694A (ko) | 2013-12-02 |
MX2013001227A (es) | 2013-04-24 |
CO6680670A2 (es) | 2013-05-31 |
EP2598140B1 (en) | 2015-01-14 |
CA2806982A1 (en) | 2012-02-02 |
AU2011282549A1 (en) | 2013-02-28 |
NZ607306A (en) | 2015-03-27 |
EP2598140A2 (en) | 2013-06-05 |
SG187653A1 (en) | 2013-03-28 |
BR112013002319A2 (pt) | 2016-05-24 |
CN103068382A (zh) | 2013-04-24 |
CL2013000308A1 (es) | 2013-04-12 |
TW201210601A (en) | 2012-03-16 |
JP2013536183A (ja) | 2013-09-19 |
WO2012016109A2 (en) | 2012-02-02 |
US20120136011A1 (en) | 2012-05-31 |
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