PE20060462A1 - Combinacion farmaceutica que comprende derivados de benzoxazinona - Google Patents

Combinacion farmaceutica que comprende derivados de benzoxazinona

Info

Publication number
PE20060462A1
PE20060462A1 PE2005000432A PE2005000432A PE20060462A1 PE 20060462 A1 PE20060462 A1 PE 20060462A1 PE 2005000432 A PE2005000432 A PE 2005000432A PE 2005000432 A PE2005000432 A PE 2005000432A PE 20060462 A1 PE20060462 A1 PE 20060462A1
Authority
PE
Peru
Prior art keywords
compounds
halogen
salts
alkyl
formula
Prior art date
Application number
PE2005000432A
Other languages
English (en)
Inventor
Ingo Konetzki
Thierry Bouyssou
Michael P Pieper
Christoph Hoenke
Klaus Rudolf
Michel Pairet
Sabine Pestel
Andreas Schnapp
Philipp Lustenberger
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34966478&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20060462(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE102004019540A external-priority patent/DE102004019540A1/de
Priority claimed from DE102004052987A external-priority patent/DE102004052987A1/de
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of PE20060462A1 publication Critical patent/PE20060462A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Abstract

REFERIDA A UNA COMBINACION FARMACEUTICA QUE COMPRENDE: UNO O MAS COMPUESTOS DERIVADOS DE BENZOXAZINONA DE FORMULA 1, DONDE n ES 1 O 2; R1 ES H, HALOGENO, ALQUILO C1-C4, ENTRE OTROS; R2 ES H, HALOGENO, ALQUILO C1-C4, ENTRE OTROS; R3 ES ALQUILO C1-C4, OH, HALOGENO, ENTRE OTROS; Y AL MENOS OTRO PRINCIPIO ACTIVO DE FORMULA 2. DENTRO DE LOS PRINCIPIOS ACTIVOS DE FORMULA 2, SE ENCUENTRAN COMPUESTOS ANTICOLINERGICOS TALES COMO SALES DE TIOTROPIO, SALES DE OXITROPIO, SALES DE IPRATROPIO, ENTRE OTROS; COMPUESTOS INHIBIDORES DE PDE IV TALES COMO TEOFILINA, PUMAFENTINA, ENTRE OTROS; COMPUESTOS ESTEROIDES TALES COMO PREDNISOLONA, BECLOMETASONA, TRIAMCINOLONA, ENTRE OTROS; COMPUESTOS ANTAGONISTAS DE LTD4 TALES COMO MONTELUKAST, MN-001, ENTRE OTROS; Y COMPUESTOS INHIBIDORES DE EGFR. DICHA COMBINACION ES UTIL PARA EL TRATAMIENTO DE ENFERMEDADES DE LAS VIAS RESPIRATORIAS TALES COMO ENFISEMAS PULMONARES, FIBROSIS QUISTICA, BRONQUIECTASIAS, ENTRE OTRAS
PE2005000432A 2004-04-22 2005-04-20 Combinacion farmaceutica que comprende derivados de benzoxazinona PE20060462A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004019540A DE102004019540A1 (de) 2004-04-22 2004-04-22 Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen
DE102004052987A DE102004052987A1 (de) 2004-11-03 2004-11-03 Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen
EP05002496 2005-02-07

Publications (1)

Publication Number Publication Date
PE20060462A1 true PE20060462A1 (es) 2006-06-19

Family

ID=34966478

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2005000432A PE20060462A1 (es) 2004-04-22 2005-04-20 Combinacion farmaceutica que comprende derivados de benzoxazinona

Country Status (31)

Country Link
EP (2) EP2422786B1 (es)
JP (1) JP2007533683A (es)
KR (2) KR20130049840A (es)
AR (1) AR049262A1 (es)
AT (1) ATE539754T1 (es)
AU (1) AU2005235419B2 (es)
BR (1) BRPI0510080B8 (es)
CA (1) CA2559699C (es)
CY (3) CY1113890T1 (es)
DK (2) DK2422786T3 (es)
EA (1) EA013157B1 (es)
EC (1) ECSP066947A (es)
ES (2) ES2380370T3 (es)
FI (1) FIC20170005I1 (es)
HU (1) HUS1500058I1 (es)
IL (2) IL177685A (es)
LT (1) LTC1781298I2 (es)
LU (1) LU93066I2 (es)
MY (1) MY148945A (es)
NL (1) NL300779I2 (es)
NO (2) NO337714B1 (es)
NZ (1) NZ550797A (es)
PE (1) PE20060462A1 (es)
PL (2) PL1781298T4 (es)
PT (2) PT2422786E (es)
SG (1) SG152237A1 (es)
SI (2) SI2422786T1 (es)
TW (2) TWI374739B (es)
UY (1) UY28861A1 (es)
WO (1) WO2005102349A1 (es)
ZA (1) ZA200606624B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
DE102004024452A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation von Betaagonisten
US7923455B2 (en) * 2005-01-28 2011-04-12 Boehringer Ingelheim International Gmbh Medicaments for the prevention or treatment of heart failure comprising administration of an anticholinergic
EP1855689A1 (en) * 2005-02-16 2007-11-21 Boehringer Ingelheim International GmbH Pharmaceutical compositions comprising anticholinergics and etiprednol
CN101208316B (zh) 2005-08-15 2012-05-09 贝林格尔·英格海姆国际有限公司 制备β-模拟物的方法
US20070088030A1 (en) * 2005-10-10 2007-04-19 Barbara Niklaus-Humke Aerosol formulations for the inhalation of beta-agonists
US20070086957A1 (en) * 2005-10-10 2007-04-19 Thierry Bouyssou Combination of medicaments for the treatment of respiratory diseases
WO2007058971A2 (en) * 2005-11-10 2007-05-24 Bodor Nicholas S Soft anticholinergic esters
WO2007093608A1 (de) * 2006-02-16 2007-08-23 Boehringer Ingelheim International Gmbh Arzneimittelkombinationen zur behandlung von atemwegserkrankungen
US20090324510A1 (en) 2006-08-07 2009-12-31 Boehringer Ingelheim International Gmbh Drug combinations for the treatment of respiratory tract diseases
UY30543A1 (es) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Formulacion de aerosol para la inhalacion de beta- agonistas
UY30542A1 (es) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Formulacion de aerosol para la inhalacion de agonistas beta
JP2010507617A (ja) * 2006-10-26 2010-03-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器系及び消化器系障害の治療用の新規な医薬組成物
EP1921070A1 (de) 2006-11-10 2008-05-14 Boehringer Ingelheim Pharma GmbH & Co. KG Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstelllung
AU2009211523B2 (en) 2008-02-07 2014-03-13 Boehringer Ingelheim International Gmbh Spirocyclic heterocycles, medicaments containing said compounds, use thereof and method for their production
CA2733153C (en) 2008-08-08 2016-11-08 Boehringer Ingelheim International Gmbh Cyclohexyloxy substituted heterocycles, pharmaceutical compositions containing these compounds and processes for preparing them
JP2012509922A (ja) * 2008-11-27 2012-04-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規粉末化結晶質吸入薬
WO2014016548A2 (en) * 2012-07-27 2014-01-30 Cipla Limited Pharmaceutical composition
EP2906218B1 (en) 2012-10-09 2016-12-14 Boehringer Ingelheim International GmbH Beta-2-adrenoceptor agonist for the treatment of cough

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4460581A (en) * 1982-10-12 1984-07-17 Boehringer Ingelheim Kg (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones
US4570630A (en) 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
AU591152B2 (en) 1985-07-30 1989-11-30 Glaxo Group Limited Devices for administering medicaments to patients
SE453566B (sv) 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
SG45171A1 (en) 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
DE4318455A1 (de) 1993-06-03 1994-12-08 Boehringer Ingelheim Kg Kapselhalterung
DE19536902A1 (de) 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
EP1305300A1 (de) 2000-04-27 2003-05-02 Boehringer Ingelheim Pharma GmbH & Co.KG Neue, langwirksame betamimetika, verfahren zu deren herstellung und deren verwendung als arzneimittel
HU226830B1 (en) 2000-10-12 2009-11-30 Boehringer Ingelheim Pharma Thiotropium bromide monohydrate, method for producing the same and a pharmaceutical composition containing the same
DK1401445T3 (da) 2001-06-22 2006-11-27 Boehringer Ingelheim Pharma Krystallinsk anticholinergikum, fremgangsmåde til fremstilling af dette og anvendelse af dette til fremstilling af et lægemiddel
DE10130371A1 (de) * 2001-06-23 2003-01-02 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika
ES2203327B1 (es) * 2002-06-21 2005-06-16 Almirall Prodesfarma, S.A. Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen.
DE10230751A1 (de) * 2002-07-09 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und EGFR-Kinase-Hemmern
DE10246374A1 (de) * 2002-10-04 2004-04-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Betamimetika mit verlängerter Wirkungsdauer, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE10253282A1 (de) * 2002-11-15 2004-05-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung

Also Published As

Publication number Publication date
CY1113890T1 (el) 2016-07-27
AU2005235419B2 (en) 2010-11-04
SG152237A1 (en) 2009-05-29
SI1781298T1 (sl) 2012-04-30
PL1781298T4 (pl) 2017-07-31
ECSP066947A (es) 2007-01-26
LU93066I2 (fr) 2016-07-11
ES2380370T3 (es) 2012-05-11
NL300779I2 (nl) 2017-11-02
JP2007533683A (ja) 2007-11-22
IL177685A (en) 2013-10-31
BRPI0510080A (pt) 2007-10-16
CY1115719T1 (el) 2017-01-25
NO337714B1 (no) 2016-06-06
FIC20170005I1 (fi) 2017-01-13
NO2016022I1 (no) 2016-12-01
IL226562A0 (en) 2013-06-27
TWI374739B (en) 2012-10-21
ATE539754T1 (de) 2012-01-15
EP2422786A1 (de) 2012-02-29
PT1781298E (pt) 2012-02-03
CY2017014I2 (el) 2017-11-14
ES2523518T3 (es) 2014-11-26
NO2016022I2 (no) 2016-12-01
CA2559699C (en) 2012-06-19
TW201231055A (en) 2012-08-01
KR101287460B1 (ko) 2013-07-23
PL2422786T3 (pl) 2015-02-27
UY28861A1 (es) 2005-11-30
PT2422786E (pt) 2014-11-12
CA2559699A1 (en) 2005-11-03
EP2422786B1 (de) 2014-08-13
HUS1500058I1 (hu) 2016-01-28
BRPI0510080B1 (pt) 2020-08-18
NZ550797A (en) 2010-08-27
IL177685A0 (en) 2006-12-31
KR20130049840A (ko) 2013-05-14
KR20070015592A (ko) 2007-02-05
TWI372056B (en) 2012-09-11
PL1781298T3 (pl) 2012-06-29
WO2005102349A1 (de) 2005-11-03
EA013157B1 (ru) 2010-02-26
EP1781298B1 (de) 2012-01-04
NO20065060L (no) 2006-11-21
EA200601846A1 (ru) 2007-04-27
AU2005235419A1 (en) 2005-11-03
DK1781298T3 (da) 2012-05-07
BRPI0510080B8 (pt) 2021-05-25
MY148945A (en) 2013-06-14
DK2422786T3 (da) 2014-11-17
CY2017014I1 (el) 2017-11-14
LTC1781298I2 (lt) 2018-09-25
ZA200606624B (en) 2008-01-08
AR049262A1 (es) 2006-07-12
SI2422786T1 (sl) 2014-12-31
EP1781298A1 (de) 2007-05-09

Similar Documents

Publication Publication Date Title
PE20060462A1 (es) Combinacion farmaceutica que comprende derivados de benzoxazinona
NO20082643L (no) Isokinolinaminopyrazolderivater, deres fremstilling og anvendelse som farmasoytiske midler for behandling av kreft
NO20074620L (no) Spiroheterocykliske forbindelser og deres anvendelse som medikamenter
PE20081362A1 (es) DERIVADOS MORFOLINO PIRIMIDINA COMO INHIBIDORES DE mTOR QUINASA Y PI3K
BRPI0510414A (pt) uso de derivados de quinolina substituìdos para o tratamento de doenças micobacterianas resistentes a fármacos
AR049711A1 (es) Compuestos heterociclicos condensados como inhibidores de la aldosterona sintasa; composiciones farmaceuticas que los contienen y su uso en la preparacion de un medicamento para el tratamiento o prevencion de enfermedades relacionadas con el hiperaldosterismo y por una liberacion excesiva de cortiso
NO20073730L (no) Amidderivater
MX2015016416A (es) Derivados de la pirazolopirrolidina y su uso en el tratamiento de enfermedades.
MX2015016344A (es) Derivados de imidazo-pirrolidinona y su uso en el tratamiento de enfermedades.
BR0317572A (pt) Benzoxazinas e seus derivados como inibidores de pi3ks
NO20072978L (no) Nye betuinderivater, preparat derav og anvendelse derav
NO20062370L (no) Amidderivater
NO20073853L (no) Faste, oralt applikerbare farmasoytiske administreringsformer inneholdende nvaroksaban med modifisert frigivelse
AR068768A1 (es) Derivados de tetrahidroquinolina para tratar trastornos por estres post - traumatico
BR112015029401A2 (pt) derivados pirazolo-pirrolidin-4-ona e seu uso no tratamento de doenças
AR072962A1 (es) Derivados de pirimidin-4-ona sustituidos
NO20084049L (no) Forbindelser med forsterket ampa receptor og anvendelse derav i medisin
PE20070708A1 (es) Formulacion en aerosol para inhalacion de beta-agonistas
PE20080607A1 (es) Formulacion en aerosol para la inhalacion de beta-agonistas
EA200971086A1 (ru) Фармацевтические композиции и способ лечения шизофрении
NO20092764L (no) Isosorbid mononitrat derivater for behandling av okular hypertensjon
BR112015022385A2 (pt) droga para uma doença respiratória
MA33563B1 (fr) 5-(3,4-dichloro-phényl)-n-(2-hydroxy-cyclohexyl)-6-(2,2,2-trifluoro-éthoxy)-nicotinamide et ses sels utilisés comme agents augmentant le cholestérol hdl
UY29739A1 (es) Derivados de amidas o sales farmacéuticamente aceptables de los mismos, procesos de preparaciones farmacéuticas conteniéndolos y aplicaciones
US9096585B2 (en) Antiviral compounds and uses thereof

Legal Events

Date Code Title Description
FG Grant, registration