PE20060075A1 - Composiciones farmaceuticas de alisciren - Google Patents

Composiciones farmaceuticas de alisciren

Info

Publication number
PE20060075A1
PE20060075A1 PE2005000288A PE2005000288A PE20060075A1 PE 20060075 A1 PE20060075 A1 PE 20060075A1 PE 2005000288 A PE2005000288 A PE 2005000288A PE 2005000288 A PE2005000288 A PE 2005000288A PE 20060075 A1 PE20060075 A1 PE 20060075A1
Authority
PE
Peru
Prior art keywords
alisciren
tablet
resulting
active ingredient
granulator
Prior art date
Application number
PE2005000288A
Other languages
English (en)
Inventor
Petra Gisela Rigassi-Dietrich
Martin Schmid
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34994415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20060075(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PE20060075A1 publication Critical patent/PE20060075A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

REFERIDA A UNA FORMULACION QUE COMPRENDE: A) UN INHIBIDOR DE RENINA TAL COMO ALISCIREN O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO, DONDE EL INGREDIENTE ACTIVO ESTA PRESENTE EN UNA CANTIDAD QUE VARIA ENTRE 46-60% EN PESO; B) UN LLENADOR TAL COMO CELULOSA MICROCRISTALINA; C) AGENTE DE DESINTEGRACION, LUBRICANTE, AGENTE DE DESLIZ, AGLUTINANTE. UN PROCEDIMIENTO DE PREPARACION COMPRENDE: 1) MEZCLAR EL INGREDIENTE ACTIVO Y ADITIVOS Y GRANULAR DICHOS COMPONENTES CON UN LIQUIDO GRANULACION; 2) SECAR UN GRANULADOR RESULTANTE; 3) MEZCLAR EL GRANULADOR SECO CON EXCIPIENTES DE FASE EXTERNA; 4) COMPRIMIR UNA MEZCLA RESULTANTE PARA FORMAR UNA DOSIS ORAL SOLIDA COMO UNA TABLETA DE NUCLEO; 5) OPCIONALMENTE RECUBRIR UNA TABLETA DE NUCLEO RESULTANTE PARA DAR UNA TABLETA CUBIERTA CON PELICULA. DICHA FORMULACION SUPERA LOS PROBLEMAS RELACIONADOS CON LAS PROPIEDADES DEL ALISCIREN. SON UTILES EN EL TRATAMIENTO DE HIPERTENSION, FALLA CARDIACA CONGESTIVA, ANGINA, INFARTO DE PECHO, DOLOR DE CABEZA, ENTRE OTROS
PE2005000288A 2004-03-17 2005-03-15 Composiciones farmaceuticas de alisciren PE20060075A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55387804P 2004-03-17 2004-03-17

Publications (1)

Publication Number Publication Date
PE20060075A1 true PE20060075A1 (es) 2006-03-20

Family

ID=34994415

Family Applications (3)

Application Number Title Priority Date Filing Date
PE2005000288A PE20060075A1 (es) 2004-03-17 2005-03-15 Composiciones farmaceuticas de alisciren
PE2014001265A PE20142101A1 (es) 2004-03-17 2005-03-15 Composiciones farmaceuticas de aliskiren
PE2010000272A PE20110121A1 (es) 2004-03-17 2005-03-15 Composiciones farmaceuticas de aliskiren

Family Applications After (2)

Application Number Title Priority Date Filing Date
PE2014001265A PE20142101A1 (es) 2004-03-17 2005-03-15 Composiciones farmaceuticas de aliskiren
PE2010000272A PE20110121A1 (es) 2004-03-17 2005-03-15 Composiciones farmaceuticas de aliskiren

Country Status (24)

Country Link
US (3) US8617595B2 (es)
EP (2) EP1729736A2 (es)
JP (2) JP2007529456A (es)
KR (2) KR101353736B1 (es)
CN (2) CN1997354B (es)
AR (1) AR048431A1 (es)
AU (2) AU2005224010B2 (es)
BR (1) BRPI0508833A (es)
CA (1) CA2554633C (es)
EC (1) ECSP066807A (es)
ES (1) ES2747941T3 (es)
IL (1) IL177424A0 (es)
MA (1) MA28490B1 (es)
MX (1) MX347617B (es)
MY (2) MY144477A (es)
NO (1) NO343217B1 (es)
NZ (1) NZ548823A (es)
PE (3) PE20060075A1 (es)
RU (3) RU2384328C2 (es)
SG (1) SG153830A1 (es)
TN (1) TNSN06294A1 (es)
TW (1) TWI406656B (es)
WO (1) WO2005089729A2 (es)
ZA (1) ZA200606220B (es)

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AU2010226620A1 (en) 2009-03-20 2011-09-22 Novartis Ag Galenical formulations of a fixed dose combination of Valsartan and Aliskiren
KR20110129482A (ko) * 2009-03-20 2011-12-01 노파르티스 아게 알리스키렌을 포함하는 제약 조성물
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Also Published As

Publication number Publication date
ECSP066807A (es) 2006-11-16
CA2554633C (en) 2014-07-08
BRPI0508833A (pt) 2007-08-14
RU2438661C2 (ru) 2012-01-10
WO2005089729A3 (en) 2006-10-12
TNSN06294A1 (en) 2007-12-03
US20070197655A1 (en) 2007-08-23
KR101353736B1 (ko) 2014-01-22
CN1997354B (zh) 2013-09-11
AU2005224010B2 (en) 2009-02-26
CN1997354A (zh) 2007-07-11
RU2009138446A (ru) 2011-04-27
SG153830A1 (en) 2009-07-29
AU2009202069B2 (en) 2012-02-16
KR101274855B1 (ko) 2013-06-13
US8007824B2 (en) 2011-08-30
ES2747941T3 (es) 2020-03-12
MY148773A (en) 2013-05-31
JP2012211152A (ja) 2012-11-01
US8617595B2 (en) 2013-12-31
RU2384328C2 (ru) 2010-03-20
MA28490B1 (fr) 2007-03-01
PE20110121A1 (es) 2011-02-28
EP2283826A3 (en) 2013-08-07
NZ548823A (en) 2011-02-25
US7683054B2 (en) 2010-03-23
AU2005224010A1 (en) 2005-09-29
TW200534843A (en) 2005-11-01
CN103462913A (zh) 2013-12-25
ZA200606220B (en) 2008-04-30
AR048431A1 (es) 2006-04-26
MY144477A (en) 2011-09-30
JP5925607B2 (ja) 2016-05-25
EP1729736A2 (en) 2006-12-13
TWI406656B (zh) 2013-09-01
RU2006136090A (ru) 2008-04-27
IL177424A0 (en) 2008-03-20
NO20064670L (no) 2006-10-16
WO2005089729A2 (en) 2005-09-29
EP2283826A2 (en) 2011-02-16
JP2007529456A (ja) 2007-10-25
NO343217B1 (no) 2018-12-03
EP2283826B1 (en) 2019-09-04
AU2009202069A1 (en) 2009-06-18
RU2011135405A (ru) 2013-03-10
US20050272790A1 (en) 2005-12-08
US20060018960A1 (en) 2006-01-26
KR20070006776A (ko) 2007-01-11
KR20130028803A (ko) 2013-03-19
CA2554633A1 (en) 2006-09-29
PE20142101A1 (es) 2014-12-27
MX347617B (es) 2017-05-04
RU2480210C1 (ru) 2013-04-27

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