PE20050201A1 - Pirazolopirimidinas sustituidas con 6-ciclilmetilo y 6-alquilmetilo - Google Patents
Pirazolopirimidinas sustituidas con 6-ciclilmetilo y 6-alquilmetiloInfo
- Publication number
- PE20050201A1 PE20050201A1 PE2004000472A PE2004000472A PE20050201A1 PE 20050201 A1 PE20050201 A1 PE 20050201A1 PE 2004000472 A PE2004000472 A PE 2004000472A PE 2004000472 A PE2004000472 A PE 2004000472A PE 20050201 A1 PE20050201 A1 PE 20050201A1
- Authority
- PE
- Peru
- Prior art keywords
- pyrazole
- methylphenyl
- alkyl
- cyclylmethyl
- alkylmethyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- -1 2-METHYLPHENYL Chemical class 0.000 abstract 2
- MJQOLPWOOIMZDA-UHFFFAOYSA-N 5-amino-1-(4-methylphenyl)pyrazole-4-carbonitrile Chemical compound C1=CC(C)=CC=C1N1C(N)=C(C#N)C=N1 MJQOLPWOOIMZDA-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical class O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000008447 perception Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10320784 | 2003-05-09 | ||
| DE10336183 | 2003-08-07 | ||
| DE102004004142A DE102004004142A1 (de) | 2003-05-09 | 2004-01-28 | 6-Cyclylmethyl- und 6-Alkylmethyl-substituierte Pyrazolopyrimidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20050201A1 true PE20050201A1 (es) | 2005-05-27 |
Family
ID=33420016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2004000472A PE20050201A1 (es) | 2003-05-09 | 2004-05-07 | Pirazolopirimidinas sustituidas con 6-ciclilmetilo y 6-alquilmetilo |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP2298773B1 (OSRAM) |
| JP (1) | JP5277303B2 (OSRAM) |
| CL (1) | CL2004000978A1 (OSRAM) |
| DE (1) | DE102004004142A1 (OSRAM) |
| MY (1) | MY148252A (OSRAM) |
| NZ (1) | NZ543812A (OSRAM) |
| PE (1) | PE20050201A1 (OSRAM) |
| RU (1) | RU2383546C2 (OSRAM) |
| TW (1) | TWI350836B (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102234131B1 (ko) * | 2013-04-05 | 2021-04-01 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 피리디닐피라졸로퀴놀린 화합물 |
| SG11201909359YA (en) | 2017-06-01 | 2019-11-28 | Eisai R&D Man Co Ltd | Pharmaceutical composition comprising pde9 inhibitor |
| CN110612102A (zh) | 2017-06-01 | 2019-12-24 | 卫材R&D管理有限公司 | 含有吡唑并喹啉衍生物的路易氏体病治疗剂 |
| IL270395B (en) | 2017-06-01 | 2022-08-01 | Eisai R&D Man Co Ltd | Dementia therapeutic agent combining pyrazoloquinoline derivative and donepezil |
| CA3060183A1 (en) | 2017-06-01 | 2018-12-06 | Eisai R&D Management Co., Ltd. | Dementia therapeutic agent combining pyrazoloquinoline derivative and memantine |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH396926A (de) | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| DE1147234B (de) | 1960-05-11 | 1963-04-18 | Ciba Geigy | Verfahren zur Herstellung von 1-Isopropyl-4-hydroxy-6-benzyl-pyrazolo[3, 4-d]pyrimidin |
| CH396925A (de) | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| CH396924A (de) | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung von 4-Mercapto-pyrazolo(3,4-d)pyrimidinen |
| CH396927A (de) | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| DE1149013B (de) | 1960-05-11 | 1963-05-22 | Ciba Geigy | Verfahren zur Herstellung von 4-Oxo-4, 5-dihydro-pyrazolo-[3, 4-d]Pyrimidinen |
| DE1161281B (de) | 1960-05-11 | 1964-01-16 | Ciba Aktiengesellschaft, Basel (Schweiz) | Verfahren zur Herstellung von 1-Alkyl-6-aralkyl-pyrazoloÄ3,4-dÜ-pyrimidinen. |
| US3732225A (en) | 1970-07-23 | 1973-05-08 | Squibb & Sons Inc | Pyrazolo(3,4-d)pyrimidine derivatives |
| US3847908A (en) | 1973-03-05 | 1974-11-12 | Squibb & Sons Inc | 6-styrylpyrazolo(3,4-d)pyrimidinones and pyrimidines |
| DK0379917T3 (da) | 1989-01-26 | 1995-12-11 | Bayer Ag | Optisk aktive (meth)acrylsyre-drivater, deres fremstilling, deres polymerisation til optisk aktive polymere og disses anvendelse |
| RU2104216C1 (ru) * | 1994-01-10 | 1998-02-10 | Акционерное общество открытого типа "Таганрогский авиационный научно-технический комплекс им.Г.М.Бериева" | Замок |
| DE19709877A1 (de) | 1997-03-11 | 1998-09-17 | Bayer Ag | 1,5-Dihydro-pyrazolo[3,4-d]-pyrimidinon-derivate |
| WO2002009713A2 (de) * | 2000-08-01 | 2002-02-07 | Bayer Aktiengesellschaft | Selektive pde 2-inhibitoren als arzneimittel zur verbesserung der wahrnehmung |
| KR20040053210A (ko) * | 2001-11-02 | 2004-06-23 | 화이자 프로덕츠 인크. | Ｐｄｅ9 억제제를 사용한 인슐린 저항 증후군 및 2형당뇨병의 치료 |
| HN2002000317A (es) * | 2001-11-02 | 2003-05-21 | Pfizer | Inhibidores de pde9 para tratamiento de trastornos cardiovasculares |
| DE10219435A1 (de) * | 2002-05-02 | 2003-11-13 | Bayer Cropscience Ag | Substituierte Pyrazolo-pyrimidin-4-one |
-
2004
- 2004-01-28 DE DE102004004142A patent/DE102004004142A1/de not_active Withdrawn
- 2004-04-28 EP EP10186283.7A patent/EP2298773B1/de not_active Expired - Lifetime
- 2004-04-28 NZ NZ543812A patent/NZ543812A/en not_active IP Right Cessation
- 2004-04-28 RU RU2005138339/04A patent/RU2383546C2/ru not_active IP Right Cessation
- 2004-05-07 CL CL200400978A patent/CL2004000978A1/es unknown
- 2004-05-07 TW TW093112841A patent/TWI350836B/zh not_active IP Right Cessation
- 2004-05-07 PE PE2004000472A patent/PE20050201A1/es not_active Application Discontinuation
- 2004-05-07 MY MYPI20041687A patent/MY148252A/en unknown
-
2011
- 2011-11-08 JP JP2011244500A patent/JP5277303B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP2298773B1 (de) | 2013-06-19 |
| DE102004004142A1 (de) | 2004-11-25 |
| JP5277303B2 (ja) | 2013-08-28 |
| CL2004000978A1 (es) | 2005-03-18 |
| TWI350836B (en) | 2011-10-21 |
| JP2012036221A (ja) | 2012-02-23 |
| TW200508237A (en) | 2005-03-01 |
| EP2298773A1 (de) | 2011-03-23 |
| NZ543812A (en) | 2010-06-25 |
| RU2005138339A (ru) | 2006-08-10 |
| MY148252A (en) | 2013-03-29 |
| RU2383546C2 (ru) | 2010-03-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |