PE20010029A1 - Androgenos oralmente activos - Google Patents

Androgenos oralmente activos

Info

Publication number
PE20010029A1
PE20010029A1 PE2000000309A PE0003092000A PE20010029A1 PE 20010029 A1 PE20010029 A1 PE 20010029A1 PE 2000000309 A PE2000000309 A PE 2000000309A PE 0003092000 A PE0003092000 A PE 0003092000A PE 20010029 A1 PE20010029 A1 PE 20010029A1
Authority
PE
Peru
Prior art keywords
orally active
alkyl
hydrogen
active androgens
acyl
Prior art date
Application number
PE2000000309A
Other languages
English (en)
Spanish (es)
Inventor
Dirk Leysen
Der Louw Jaap Van
Bursi Roberta Buma
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of PE20010029A1 publication Critical patent/PE20010029A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074—Esters

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
PE2000000309A 1999-04-06 2000-04-06 Androgenos oralmente activos PE20010029A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99201070 1999-04-06

Publications (1)

Publication Number Publication Date
PE20010029A1 true PE20010029A1 (es) 2001-01-26

Family

ID=8240066

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2000000309A PE20010029A1 (es) 1999-04-06 2000-04-06 Androgenos oralmente activos

Country Status (10)

Country Link
US (2) US6756366B1 (https=)
EP (1) EP1212345B1 (https=)
JP (1) JP2002541153A (https=)
AT (1) ATE246703T1 (https=)
AU (1) AU5209600A (https=)
CO (1) CO5160345A1 (https=)
DE (1) DE60004377T2 (https=)
ES (1) ES2204613T3 (https=)
PE (1) PE20010029A1 (https=)
WO (1) WO2000059920A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE246703T1 (de) * 1999-04-06 2003-08-15 Akzo Nobel Nv Oral wirksame 7-alpha-alkyl androgene
DE10104327A1 (de) * 2001-01-24 2002-07-25 Schering Ag 11beta-Halogensteroide, deren Herstellung und Verwendung zur Herstellung von Arzneimitteln sowie 11beta-Halogensteroide enthaltende pharmazeutische Präparate
WO2003059931A1 (en) * 2002-01-21 2003-07-24 Akzo Nobel N.V. PROCESS FOR THE PREPARATION OF 7α-METHYLSTEROIDS
GB0304927D0 (en) 2003-03-04 2003-04-09 Resolution Chemicals Ltd Process for the production of tibolone
PE20050677A1 (es) 2003-12-22 2005-10-04 Akzo Nobel Nv Esteroides con perfil androgenico y progestagenico mixto
DK2278880T3 (da) * 2008-04-09 2012-11-12 Pherin Pharm Inc Steroidbehandling af hedeture
US20120214987A1 (en) * 2010-12-15 2012-08-23 Yu Ge Methods and compounds for preparing 3alpha-oxygen substituted steroids

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE755689A (fr) * 1969-09-03 1971-03-03 Upjohn Co Procede de fabrication de nouvelles 7 beta-alkyl-19- nortestosterones
US5342834A (en) * 1989-04-07 1994-08-30 The Population Council, Inc. Method for androgen supplementation
US5395627A (en) * 1992-09-04 1995-03-07 Akzo N.V. Pharmaceutical granulate
US6037339A (en) * 1993-02-08 2000-03-14 Akzo Nobel N.V. C-11 substituted steroids for treating menopausal complaints
ES2134313T3 (es) * 1993-03-05 1999-10-01 Akzo Nobel Nv Utilizacion de derivados de pregnano para el tratamiento de tumores.
IL113816A (en) * 1994-06-08 1998-12-06 Akzo Nobel Nv Pharmaceutical compositions containing desogestrel their preparation and use
IL115445A (en) * 1994-10-17 1999-08-17 Akzo Nobel Nv Solid pharmaceutical compositions comprising low dosage active ingredient oil and excipient capable of binding water and their preparation
RU2159618C2 (ru) * 1995-06-22 2000-11-27 Акцо Нобель Н.В. Прессованные таблетки дезогестрела, изготовленные способом сухого гранулирования
IL118974A (en) * 1995-08-17 2001-09-13 Akzo Nobel Nv History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
ZA968873B (en) * 1995-11-06 1997-05-28 Akzo Nobel Nv Isomerisation of equillin
US5998639A (en) * 1995-11-06 1999-12-07 Akzo Nobel, N.V. Sulfatation of estrogen mixtures
CA2200423C (en) * 1996-03-26 2006-12-19 Sietse Mosselman Novel estrogen receptor
US6506390B2 (en) * 1996-06-25 2003-01-14 Akzo Nobel Progestogen-anti-progestogen regimens
TW403736B (en) * 1997-02-21 2000-09-01 Akzo Nobel Nv Steroid compounds having contraceptive and anti-osteoporosis activity
US6177420B1 (en) * 1997-05-16 2001-01-23 Akzo Nobel N.V. 20-aralkyl-5α-pregnane derivatives
US6262282B1 (en) * 1997-06-04 2001-07-17 Akzo Nobel N.V. 17β-allyloxy(thio)alkyl-androstane derivatives for the modulation of meiosis
EP0927556B1 (en) * 1997-09-23 2000-08-30 Akzo Nobel N.V. Dosage units of steroids with a seal coating for the steroids
US6080773A (en) * 1997-10-14 2000-06-27 Akzo Nobel, N.V. Benzylamine derivatives which are useful in treating psychiatric disorders
NZ504351A (en) * 1997-11-14 2002-10-25 Akzo Nobel Nv Contraceptive kit comprising progestogen and anti-progestogen and use in treating bleeding induced by a progestogen-only contraceptive regimen
DK1042353T3 (da) * 1997-12-18 2002-11-04 Akzo Nobel Nv 17-beta-aryl(arylmethyl)oxy(thio)alkylandrostanderivater
NZ506465A (en) * 1998-02-26 2003-08-29 Akzo Nobel Nv Derivatives of azetidine and pyrrolidine
NZ508299A (en) * 1998-06-19 2003-04-29 Akzo Nobel Nv Testosterone derivative
AU759344B2 (en) * 1998-12-11 2003-04-10 Akzo Nobel N.V. 22S-hydroxycholesta-8, 14-diene derivatives with meiosis regulating activity
US6498153B1 (en) * 1998-12-31 2002-12-24 Akzo Nobel N.V. Extended release growth promoting two component composition
ATE229538T1 (de) * 1999-03-09 2002-12-15 Akzo Nobel Nv 22r-hydroxycholesta-8,14-diene derivate zur hemmung der meiose
ATE246703T1 (de) * 1999-04-06 2003-08-15 Akzo Nobel Nv Oral wirksame 7-alpha-alkyl androgene
TW548277B (en) * 1999-07-16 2003-08-21 Akzo Nobel Nv Orally active androgens
US6677329B1 (en) * 1999-09-06 2004-01-13 Akzo Nobel N V. Non-aromatic estrogenic steroids with a hydrocarbon substituent in position 11
AU778017B2 (en) * 1999-12-02 2004-11-11 N.V. Organon 14,15-beta-methylene substituted androgens
DE60130748T2 (de) * 2000-03-27 2008-07-17 N.V. Organon Nicht-steroidale tetracyclische verbindungen für östrogen-verwandte behandlungen
KR20030027052A (ko) * 2000-08-23 2003-04-03 악조 노벨 엔.브이. 의료용 10-아릴-11Ｈ-벤조[ｂ]플루오렌 유도체 및 유사체

Also Published As

Publication number Publication date
ES2204613T3 (es) 2004-05-01
CO5160345A1 (es) 2002-05-30
WO2000059920A3 (en) 2001-02-15
EP1212345B1 (en) 2003-08-06
US20040209853A1 (en) 2004-10-21
WO2000059920A2 (en) 2000-10-12
JP2002541153A (ja) 2002-12-03
AU5209600A (en) 2000-10-23
DE60004377D1 (de) 2003-09-11
DE60004377T2 (de) 2004-06-09
ATE246703T1 (de) 2003-08-15
EP1212345A2 (en) 2002-06-12
US6756366B1 (en) 2004-06-29

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