PE20001332A1 - Derivados n-fenil-n`-fenilpropilpiperazina y un metodo para su produccion - Google Patents

Derivados n-fenil-n`-fenilpropilpiperazina y un metodo para su produccion

Info

Publication number
PE20001332A1
PE20001332A1 PE1999001244A PE00124499A PE20001332A1 PE 20001332 A1 PE20001332 A1 PE 20001332A1 PE 1999001244 A PE1999001244 A PE 1999001244A PE 00124499 A PE00124499 A PE 00124499A PE 20001332 A1 PE20001332 A1 PE 20001332A1
Authority
PE
Peru
Prior art keywords
phenylpropylpiperazine
phenyl
derivatives
production
refers
Prior art date
Application number
PE1999001244A
Other languages
English (en)
Inventor
Hiroki Sato
Eiichi Nagano
Jun Chikazawa
Mineo Takei
Raita Higashino
Original Assignee
Zeria Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeria Pharm Co Ltd filed Critical Zeria Pharm Co Ltd
Publication of PE20001332A1 publication Critical patent/PE20001332A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A UN DERIVADO N-FENIL-N`-FENILPROPILPIPERAZINA DE FORMULA I, DONDE: R1 ES ALQUILO, R2 ES ALCOXI, R3 ES CIANO, CARBOXILO, INDOLCARBONILO. TAMBIEN SE REFIERE A PROCEDIMIENTOS PARA LA PREPARACION. EL COMPUESTO I ES UN AGENTE BLOQUEANTE DE O1-ADRENERGICOS POR LO QUE PUEDE SER UTIL PARA EL TRATAMIENTO DE LA HIPERTENSION, FALLO CARDIACO CONGESTIVO, ISQUEMIA MIOCARDICA, ARRITMIA, ANGINA DE PECHO, DISURIA
PE1999001244A 1998-06-30 1999-12-14 Derivados n-fenil-n`-fenilpropilpiperazina y un metodo para su produccion PE20001332A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP19814898 1998-06-30

Publications (1)

Publication Number Publication Date
PE20001332A1 true PE20001332A1 (es) 2000-12-19

Family

ID=16386265

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1999001244A PE20001332A1 (es) 1998-06-30 1999-12-14 Derivados n-fenil-n`-fenilpropilpiperazina y un metodo para su produccion

Country Status (14)

Country Link
US (1) US6395739B1 (es)
EP (1) EP1090913A4 (es)
KR (1) KR20010053010A (es)
CN (1) CN1307563A (es)
AU (1) AU742720B2 (es)
BR (1) BR9911992A (es)
CA (1) CA2336083A1 (es)
HU (1) HUP0102609A3 (es)
NO (1) NO20006542L (es)
PE (1) PE20001332A1 (es)
PL (1) PL345166A1 (es)
TR (1) TR200003884T2 (es)
WO (1) WO2000000471A1 (es)
ZA (1) ZA200007636B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4117417A1 (de) * 1991-05-28 1992-12-03 Herberts Gmbh Waessrige dispersion eines kathodisch abscheidbaren bindemittels, verfahren zu deren herstellung und deren verwendung
CN1172919C (zh) * 2002-06-03 2004-10-27 上海医药工业研究院 芳烷醇哌嗪衍生物及其在制备抗抑郁症药物中的应用
HUP0700353A2 (en) * 2007-05-18 2008-12-29 Richter Gedeon Nyrt Metabolites of (thio)carbamoyl-cyclohexane derivatives
US20090076043A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched alfuzosin
CA2715760C (en) * 2008-02-21 2017-06-13 Mitsubishi Tanabe Pharma Corporation Solid preparation for oral administration of cariprazine hydrochloride
SG192507A1 (en) 2008-07-16 2013-08-30 Richter Gedeon Nyrt Pharmaceutical formulations containing dopamine receptor ligands
JP2017214342A (ja) * 2016-06-02 2017-12-07 日清オイリオグループ株式会社 排尿障害の予防用又は改善用組成物
US11274087B2 (en) 2016-07-08 2022-03-15 Richter Gedeon Nyrt. Industrial process for the preparation of cariprazine
US11547707B2 (en) 2019-04-10 2023-01-10 Richter Gedeon Nyrt. Carbamoyl cyclohexane derivatives for treating autism spectrum disorder

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH446348A (de) 1963-01-23 1967-11-15 Ciba Geigy Verfahren zur Herstellung von Piperazinverbindungen
GB9021535D0 (en) * 1990-10-03 1990-11-14 Wyeth John & Brother Ltd Piperazine derivatives
EP0576766A1 (en) * 1992-06-29 1994-01-05 Novo Nordisk A/S Propanolamine derivatives, their preparation and use
KR100349634B1 (ko) * 1994-03-30 2003-01-08 제리아 신야쿠 고교 가부시키 가이샤 인돌유도체및이를함유하는제제

Also Published As

Publication number Publication date
EP1090913A4 (en) 2001-11-07
ZA200007636B (en) 2001-07-09
KR20010053010A (ko) 2001-06-25
US6395739B1 (en) 2002-05-28
NO20006542L (no) 2001-02-28
TR200003884T2 (tr) 2001-05-21
HUP0102609A2 (hu) 2001-12-28
AU742720B2 (en) 2002-01-10
PL345166A1 (en) 2001-12-03
CN1307563A (zh) 2001-08-08
EP1090913A1 (en) 2001-04-11
CA2336083A1 (en) 2000-01-06
WO2000000471A1 (fr) 2000-01-06
AU4290399A (en) 2000-01-17
NO20006542D0 (no) 2000-12-21
BR9911992A (pt) 2001-03-27
HUP0102609A3 (en) 2002-12-28

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