HUP0102609A2 - N-Fenil-N'-(fenil-propil)-piperazin-származékok és eljárás a vegyületek előállítására, valamint a vegyületeket tartalmazó gyógyszerkészítmények - Google Patents

N-Fenil-N'-(fenil-propil)-piperazin-származékok és eljárás a vegyületek előállítására, valamint a vegyületeket tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0102609A2
HUP0102609A2 HU0102609A HUP0102609A HUP0102609A2 HU P0102609 A2 HUP0102609 A2 HU P0102609A2 HU 0102609 A HU0102609 A HU 0102609A HU P0102609 A HUP0102609 A HU P0102609A HU P0102609 A2 HUP0102609 A2 HU P0102609A2
Authority
HU
Hungary
Prior art keywords
phenylpropylpiperazine
phenyl
derivatives
preparation
pharmaceutical compositions
Prior art date
Application number
HU0102609A
Other languages
English (en)
Inventor
Jun Chikazawa
Raita Higashino
Eiichi Nagano
Hiroki Sato
Mineo Takei
Original Assignee
Zeria Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeria Pharmaceutical Co., Ltd. filed Critical Zeria Pharmaceutical Co., Ltd.
Publication of HUP0102609A2 publication Critical patent/HUP0102609A2/hu
Publication of HUP0102609A3 publication Critical patent/HUP0102609A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU0102609A 1998-06-30 1999-06-28 N-phenyl-n'-phenylpropylpiperazine derivatives and process for the preparation thereof, and pharmaceutical compositions containing them HUP0102609A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19814898 1998-06-30
PCT/JP1999/003448 WO2000000471A1 (fr) 1998-06-30 1999-06-28 Derives de n-phenyle-n'-phenylpropilpiperazine et leur procede de preparation

Publications (2)

Publication Number Publication Date
HUP0102609A2 true HUP0102609A2 (hu) 2001-12-28
HUP0102609A3 HUP0102609A3 (en) 2002-12-28

Family

ID=16386265

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102609A HUP0102609A3 (en) 1998-06-30 1999-06-28 N-phenyl-n'-phenylpropylpiperazine derivatives and process for the preparation thereof, and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (1) US6395739B1 (hu)
EP (1) EP1090913A4 (hu)
KR (1) KR20010053010A (hu)
CN (1) CN1307563A (hu)
AU (1) AU742720B2 (hu)
BR (1) BR9911992A (hu)
CA (1) CA2336083A1 (hu)
HU (1) HUP0102609A3 (hu)
NO (1) NO20006542L (hu)
PE (1) PE20001332A1 (hu)
PL (1) PL345166A1 (hu)
TR (1) TR200003884T2 (hu)
WO (1) WO2000000471A1 (hu)
ZA (1) ZA200007636B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4117417A1 (de) * 1991-05-28 1992-12-03 Herberts Gmbh Waessrige dispersion eines kathodisch abscheidbaren bindemittels, verfahren zu deren herstellung und deren verwendung
CN1172919C (zh) * 2002-06-03 2004-10-27 上海医药工业研究院 芳烷醇哌嗪衍生物及其在制备抗抑郁症药物中的应用
HUP0700353A2 (en) * 2007-05-18 2008-12-29 Richter Gedeon Nyrt Metabolites of (thio)carbamoyl-cyclohexane derivatives
US20090076043A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched alfuzosin
JP4409630B2 (ja) * 2008-02-21 2010-02-03 田辺三菱製薬株式会社 経口投与用固形製剤
NZ590852A (en) 2008-07-16 2013-03-28 Richter Gedeon Nyrt Pharmaceutical formulations containing dopamine receptor ligands trans-1{ 4-[2-[4-(2,3-dichlorophenyl)-piperizin-1-yl]-ethyl]-cyclohexyl} -3,3-dimethyl-urea also known as cariprazine
JP2017214342A (ja) * 2016-06-02 2017-12-07 日清オイリオグループ株式会社 排尿障害の予防用又は改善用組成物
US11274087B2 (en) 2016-07-08 2022-03-15 Richter Gedeon Nyrt. Industrial process for the preparation of cariprazine
US11547707B2 (en) 2019-04-10 2023-01-10 Richter Gedeon Nyrt. Carbamoyl cyclohexane derivatives for treating autism spectrum disorder

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH446346A (de) * 1963-01-23 1967-11-15 Ciba Geigy Verfahren zur Herstellung von Piperazinverbindungen
GB9021535D0 (en) * 1990-10-03 1990-11-14 Wyeth John & Brother Ltd Piperazine derivatives
EP0576766A1 (en) 1992-06-29 1994-01-05 Novo Nordisk A/S Propanolamine derivatives, their preparation and use
US5760040A (en) * 1994-03-30 1998-06-02 Zeria Pharmaceutical Co., Ltd. Indole derivative for treating overproduction of dihydrotestosterone

Also Published As

Publication number Publication date
EP1090913A4 (en) 2001-11-07
US6395739B1 (en) 2002-05-28
TR200003884T2 (tr) 2001-05-21
PE20001332A1 (es) 2000-12-19
CN1307563A (zh) 2001-08-08
AU742720B2 (en) 2002-01-10
NO20006542L (no) 2001-02-28
ZA200007636B (en) 2001-07-09
EP1090913A1 (en) 2001-04-11
BR9911992A (pt) 2001-03-27
CA2336083A1 (en) 2000-01-06
HUP0102609A3 (en) 2002-12-28
AU4290399A (en) 2000-01-17
WO2000000471A1 (fr) 2000-01-06
KR20010053010A (ko) 2001-06-25
NO20006542D0 (no) 2000-12-21
PL345166A1 (en) 2001-12-03

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