PE20001326A1 - Composicion farmaceutica que comprende cefuroxima-axetil, polimero y/o adsorbente - Google Patents

Composicion farmaceutica que comprende cefuroxima-axetil, polimero y/o adsorbente

Info

Publication number
PE20001326A1
PE20001326A1 PE1999001186A PE00118699A PE20001326A1 PE 20001326 A1 PE20001326 A1 PE 20001326A1 PE 1999001186 A PE1999001186 A PE 1999001186A PE 00118699 A PE00118699 A PE 00118699A PE 20001326 A1 PE20001326 A1 PE 20001326A1
Authority
PE
Peru
Prior art keywords
polymer
adsorbent
cefuroxima
axetile
pharmaceutical composition
Prior art date
Application number
PE1999001186A
Other languages
English (en)
Inventor
Johannes Raneburger
Herwig Hennewein
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of PE20001326A1 publication Critical patent/PE20001326A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

SE REFIERE A CEFUROXIMA ACETIL EN FORMA i)NO GELATINOSA AL CONTACTO CON UN LIQUIDO ACUOSO; ii)UNA SOLUCION SOLIDA EN UN POLIMERO; SIENDO LA PROPORCION EN PESO DE CEFUROXIMA ACETIL Y EL POLIMERO DE 1:0,15 A 1:0,6; iii)DE UNA DISPERSION SOLIDA SOBRE UN ADSORBENTE; TAMBIEN SE REFIERE A UN GRANULADO, POLVO SECO, JARABE, SUSPENSION, TABLETA; QUE COMPRENDEN CEFUROXIMA ACETIL EN FORMA NO GELATINOSA AL CONTACTO CON EL LIQUIDO ACUOSO Y UN POLIMERO O ADSORBENTE, EXCIPIENTES; SIENDO LA TABLETA RECUBIERTA CON UNA PELICULA, TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION
PE1999001186A 1998-11-26 1999-11-25 Composicion farmaceutica que comprende cefuroxima-axetil, polimero y/o adsorbente PE20001326A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0198998A AT413647B (de) 1998-11-26 1998-11-26 Verwendung eines copolymerisats aus 1-vinyl-2-pyrrolidon und vinylacetat zur herstellung von cefuroximaxetil-hältigen tabletten

Publications (1)

Publication Number Publication Date
PE20001326A1 true PE20001326A1 (es) 2000-12-12

Family

ID=3525440

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1999001186A PE20001326A1 (es) 1998-11-26 1999-11-25 Composicion farmaceutica que comprende cefuroxima-axetil, polimero y/o adsorbente

Country Status (30)

Country Link
US (1) US6727243B1 (es)
EP (1) EP1133298B1 (es)
JP (1) JP2002530338A (es)
KR (1) KR20010080566A (es)
CN (1) CN1330546A (es)
AR (1) AR021405A1 (es)
AT (3) AT413647B (es)
AU (1) AU759517B2 (es)
BR (1) BR9915694A (es)
CA (1) CA2348876A1 (es)
CO (1) CO5190668A1 (es)
CZ (1) CZ20011845A3 (es)
DE (1) DE69935609T2 (es)
ES (1) ES2285866T3 (es)
HU (1) HUP0104412A3 (es)
ID (1) ID28615A (es)
IL (1) IL142762A0 (es)
MY (1) MY129564A (es)
NO (1) NO20012526D0 (es)
NZ (1) NZ511588A (es)
PE (1) PE20001326A1 (es)
PL (1) PL348744A1 (es)
RU (1) RU2248794C2 (es)
SI (1) SI1133298T1 (es)
SK (1) SK7162001A3 (es)
TR (1) TR200101417T2 (es)
TW (1) TWI229603B (es)
WO (1) WO2000030647A1 (es)
YU (1) YU34601A (es)
ZA (1) ZA200103927B (es)

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KR100342943B1 (ko) * 1999-08-04 2002-07-02 민경윤 비결정질 세푸록심 악세틸 고형분산체, 이의 제조 방법 및 이를 포함하는 경구투여용 조성물
US7527807B2 (en) * 2000-06-21 2009-05-05 Cubist Pharmaceuticals, Inc. Compositions and methods for increasing the oral absorption of antimicrobials
EP1414417A1 (en) * 2000-12-01 2004-05-06 Abdul Rehman Wockhardt Research Centre Khan Pharmaceutical formulation
EP1911462A3 (en) * 2001-01-26 2011-11-30 Schering Corporation Compositions comprising a sterol absorption inhibitor
US6524617B1 (en) * 2001-07-25 2003-02-25 Isp Investments Inc. Synergistic filler composition
MY148466A (en) 2001-10-26 2013-04-30 Merck Frosst Canada Ltd Granule formulation
HRP20020924A2 (en) * 2001-11-23 2003-10-31 Glaxo Group Ltd Pharmaceutical composition
JP4526247B2 (ja) * 2002-07-08 2010-08-18 第一三共株式会社 経口用セファロスポリン製剤
TW200404550A (en) * 2002-07-08 2004-04-01 Sankyo Co Cepharospolin formulation for oral use
AU2003260803A1 (en) * 2002-08-30 2004-03-19 Orchid Chemicals And Pharmaceuticals Ltd. Sustained release pharmaceutical composition
WO2005002540A2 (en) * 2003-07-01 2005-01-13 Ranbaxy Laboratories Limited Dry powder pharmaceutical suspension compositions of cefuroxime axetil
KR100552567B1 (ko) * 2003-08-23 2006-02-15 한국유나이티드제약 주식회사 수분 흡수에 안정하고 빠르게 붕해되는 세푸록심 악세틸을포함하는 정제의 조성물 및 제조 방법
US8968781B2 (en) * 2005-04-29 2015-03-03 Cubist Pharmaceuticals, Inc. Therapeutic compositions
CN100402035C (zh) * 2005-07-07 2008-07-16 石药集团中奇制药技术（石家庄）有限公司 一种微囊化头孢呋辛酯的药物组合物
US8900605B2 (en) 2010-06-14 2014-12-02 Ratiopharm Gmbh Solid ivabradine-containing composition
WO2014023710A1 (en) * 2012-08-07 2014-02-13 Sandoz Ag UNCOATED TABLET COMPRISING GRANULES INCLUDING A β-LACTAM ANTIBIOTIC AND HIGHLY DISPERSED SILICONE DIOXIDE
CA2910121A1 (en) 2013-04-25 2014-10-30 Kyorin Pharmaceutical Co., Ltd. A pharmaceutical composition comprising a 1,4-dihydroquinoline carboxylic acid a cellulosic excipient and a salting-out agent
CN105338982B (zh) 2013-04-25 2017-10-10 杏林制药株式会社 固体药用组合物
EP3210607A4 (en) 2014-10-23 2018-06-06 Kyorin Pharmaceutical Co., Ltd. Solid pharmaceutical composition

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Also Published As

Publication number Publication date
AT413647B (de) 2006-04-15
DE69935609D1 (de) 2007-05-03
CA2348876A1 (en) 2000-06-02
EP1133298A1 (en) 2001-09-19
TR200101417T2 (tr) 2001-11-21
WO2000030647A1 (en) 2000-06-02
AU759517B2 (en) 2003-04-17
US6727243B1 (en) 2004-04-27
ZA200103927B (en) 2002-05-15
AT500135A1 (de) 2005-11-15
ATE357237T1 (de) 2007-04-15
DE69935609T2 (de) 2007-12-06
TWI229603B (en) 2005-03-21
SI1133298T1 (sl) 2007-10-31
SK7162001A3 (en) 2001-10-08
KR20010080566A (ko) 2001-08-22
NO20012526L (no) 2001-05-23
JP2002530338A (ja) 2002-09-17
RU2248794C2 (ru) 2005-03-27
BR9915694A (pt) 2001-08-14
AR021405A1 (es) 2002-07-17
CO5190668A1 (es) 2002-08-29
ID28615A (id) 2001-06-21
ATA198998A (de) 2005-09-15
YU34601A (sh) 2004-09-03
NZ511588A (en) 2003-08-29
NO20012526D0 (no) 2001-05-23
CN1330546A (zh) 2002-01-09
AU1654400A (en) 2000-06-13
HUP0104412A2 (hu) 2002-04-29
EP1133298B1 (en) 2007-03-21
HUP0104412A3 (en) 2002-08-28
MY129564A (en) 2007-04-30
CZ20011845A3 (cs) 2001-08-15
ES2285866T3 (es) 2007-11-16
IL142762A0 (en) 2002-03-10
PL348744A1 (en) 2002-06-03

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