PA8652101A1 - Compuestos de imidazo(1,2-a)piridina, composiciones, usos y métodos relacionados - Google Patents
Compuestos de imidazo(1,2-a)piridina, composiciones, usos y métodos relacionadosInfo
- Publication number
- PA8652101A1 PA8652101A1 PA20058652101A PA8652101A PA8652101A1 PA 8652101 A1 PA8652101 A1 PA 8652101A1 PA 20058652101 A PA20058652101 A PA 20058652101A PA 8652101 A PA8652101 A PA 8652101A PA 8652101 A1 PA8652101 A1 PA 8652101A1
- Authority
- PA
- Panama
- Prior art keywords
- piridine
- compositions
- compounds
- related methods
- imidazo compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A NUEVOS COMPUESTOS DE IMIDAZO [1, 2-A) PIRIDINA DE FORMULA GENERAL (I): ASI COMO LAS CORRESPONDIENTE SALES FARMACEUTICAMENTE ACEPTABLES; DONDE R1, R2, R3 Y R4 TIENEN EL SIGNIFICADO DEFINIDO EN LAS REIVINDICACIONES. LOS COMPUESTOS POSEEN AFINIDAD ESPECIFICA POR EL RECEPTOR GABAA Y SON POR LO TANTO UTILES EN EL TRATAMIENTO Y PREVENCION DE LAS ENFERMEDADES MODULADAS POR LAS SUBUNIDADES A1 Y A2 DE LOS RECPTORES GABAA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04105698 | 2004-11-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8652101A1 true PA8652101A1 (es) | 2006-10-13 |
Family
ID=34929843
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20058652101A PA8652101A1 (es) | 2004-11-11 | 2005-11-08 | Compuestos de imidazo(1,2-a)piridina, composiciones, usos y métodos relacionados |
Country Status (24)
Country | Link |
---|---|
US (1) | US20080200473A1 (es) |
EP (1) | EP1814880B1 (es) |
JP (1) | JP2008519805A (es) |
KR (1) | KR20070084026A (es) |
CN (1) | CN101065377B (es) |
AR (1) | AR051626A1 (es) |
AT (1) | ATE421962T1 (es) |
AU (1) | AU2005303811A1 (es) |
BR (1) | BRPI0517796A (es) |
CA (1) | CA2585315A1 (es) |
DE (1) | DE602005012598D1 (es) |
DK (1) | DK1814880T3 (es) |
ES (1) | ES2321858T3 (es) |
IL (1) | IL182963A0 (es) |
MX (1) | MX2007005611A (es) |
NO (1) | NO20072831L (es) |
PA (1) | PA8652101A1 (es) |
PE (1) | PE20060967A1 (es) |
PL (1) | PL1814880T3 (es) |
PT (1) | PT1814880E (es) |
RU (1) | RU2007121864A (es) |
TW (1) | TWI357412B (es) |
UY (1) | UY29204A1 (es) |
WO (1) | WO2006051063A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003078448A1 (en) | 2002-03-13 | 2003-09-25 | Signum Biosciences, Inc. | Modulation of protein methylation and phosphoprotein phosphate |
US7923041B2 (en) | 2005-02-03 | 2011-04-12 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
WO2006084033A1 (en) | 2005-02-03 | 2006-08-10 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
EP1845098A1 (en) * | 2006-03-29 | 2007-10-17 | Ferrer Internacional, S.A. | Imidazo[1,2-b]pyridazines, their processes of preparation and their use as GABA receptor ligands |
MX2008014796A (es) * | 2006-05-31 | 2008-12-02 | Hoffmann La Roche | Derivados de aril-4-etinil-isoxazol. |
EP2752415B8 (en) * | 2006-08-24 | 2017-11-15 | Australian Nuclear Science & Technology Organisation | Fluorinated ligands for targeting peripheral benzodiazepine receptors |
CA2758424C (en) | 2008-04-21 | 2018-03-06 | Signum Biosciences, Inc. | Tryptamine derivatives as pp2a methylation modulators |
CA2724842A1 (en) | 2008-05-19 | 2009-11-26 | Sunovion Pharmaceuticals Inc. | Imidazo[1,2-a]pyridine compounds |
US10478438B2 (en) | 2008-10-16 | 2019-11-19 | David Reed Helton | Treatment of organophosphate exposure with ocinaplon |
JP2012510983A (ja) * | 2008-12-04 | 2012-05-17 | プロキシマジェン エルティーディー | イミダゾピリジン化合物 |
EP2496578A4 (en) | 2009-11-05 | 2013-08-21 | Univ Notre Dame Du Lac | IMIDAZO [1,2-A] PYRIDINE COMPOUNDS, THEIR SYNTHESIS AND METHODS OF USE THEREOF |
EP2617715A4 (en) * | 2010-09-17 | 2014-02-26 | Taisho Pharmaceutical Co Ltd | GLYCINE TRANSPORTER INHIBITOR |
WO2017049321A1 (en) | 2015-09-17 | 2017-03-23 | Miller Marvin J | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection |
CN106906486B (zh) * | 2017-02-22 | 2018-12-11 | 华南理工大学 | 3-溴-2-苯基-咪唑并[1,2-α]吡啶类衍生物的电化学合成方法 |
US20230121497A1 (en) * | 2020-01-29 | 2023-04-20 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2568880B1 (fr) * | 1984-08-07 | 1986-12-12 | Synthelabo | Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique |
FR2593181B1 (fr) * | 1986-01-22 | 1988-04-01 | Synthelabo | Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique |
FR2593818B1 (fr) * | 1986-02-05 | 1988-04-29 | Synthelabo | Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridine, leur preparation et leur application en therapeutique |
ES2032455T3 (es) * | 1986-01-22 | 1993-02-16 | Synthelabo | Procedimiento para preparar derivados de 3-acilaminometil-imidazo (-1,2-a)piridinas. |
WO2004066930A2 (en) * | 2003-01-27 | 2004-08-12 | Arthur Zaks | Method for inducing pain relief using imidazo[1,2-a]pyridine derivatives |
-
2005
- 2005-11-04 KR KR1020077010318A patent/KR20070084026A/ko not_active Application Discontinuation
- 2005-11-04 BR BRPI0517796-0A patent/BRPI0517796A/pt not_active IP Right Cessation
- 2005-11-04 ES ES05808135T patent/ES2321858T3/es active Active
- 2005-11-04 CN CN2005800386913A patent/CN101065377B/zh not_active Expired - Fee Related
- 2005-11-04 US US11/667,494 patent/US20080200473A1/en not_active Abandoned
- 2005-11-04 WO PCT/EP2005/055753 patent/WO2006051063A1/en active Application Filing
- 2005-11-04 PL PL05808135T patent/PL1814880T3/pl unknown
- 2005-11-04 AU AU2005303811A patent/AU2005303811A1/en not_active Abandoned
- 2005-11-04 RU RU2007121864/04A patent/RU2007121864A/ru not_active Application Discontinuation
- 2005-11-04 DK DK05808135T patent/DK1814880T3/da active
- 2005-11-04 DE DE602005012598T patent/DE602005012598D1/de active Active
- 2005-11-04 AT AT05808135T patent/ATE421962T1/de active
- 2005-11-04 JP JP2007540634A patent/JP2008519805A/ja active Pending
- 2005-11-04 EP EP05808135A patent/EP1814880B1/en not_active Not-in-force
- 2005-11-04 MX MX2007005611A patent/MX2007005611A/es active IP Right Grant
- 2005-11-04 PT PT05808135T patent/PT1814880E/pt unknown
- 2005-11-04 CA CA002585315A patent/CA2585315A1/en not_active Abandoned
- 2005-11-07 PE PE2005001302A patent/PE20060967A1/es not_active Application Discontinuation
- 2005-11-08 TW TW094139042A patent/TWI357412B/zh not_active IP Right Cessation
- 2005-11-08 PA PA20058652101A patent/PA8652101A1/es unknown
- 2005-11-09 AR ARP050104693A patent/AR051626A1/es not_active Application Discontinuation
- 2005-11-10 UY UY29204A patent/UY29204A1/es not_active Application Discontinuation
-
2007
- 2007-05-03 IL IL182963A patent/IL182963A0/en unknown
- 2007-06-04 NO NO20072831A patent/NO20072831L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN101065377A (zh) | 2007-10-31 |
DK1814880T3 (da) | 2009-05-18 |
PL1814880T3 (pl) | 2009-07-31 |
TW200624432A (en) | 2006-07-16 |
UY29204A1 (es) | 2006-01-31 |
NO20072831L (no) | 2007-08-01 |
JP2008519805A (ja) | 2008-06-12 |
CN101065377B (zh) | 2011-07-27 |
WO2006051063A1 (en) | 2006-05-18 |
IL182963A0 (en) | 2007-08-19 |
DE602005012598D1 (de) | 2009-03-19 |
EP1814880B1 (en) | 2009-01-28 |
US20080200473A1 (en) | 2008-08-21 |
TWI357412B (en) | 2012-02-01 |
BRPI0517796A (pt) | 2008-10-28 |
AU2005303811A1 (en) | 2006-05-18 |
KR20070084026A (ko) | 2007-08-24 |
PT1814880E (pt) | 2009-04-23 |
EP1814880A1 (en) | 2007-08-08 |
MX2007005611A (es) | 2007-07-11 |
CA2585315A1 (en) | 2006-05-18 |
RU2007121864A (ru) | 2008-12-20 |
PE20060967A1 (es) | 2006-09-20 |
ES2321858T3 (es) | 2009-06-12 |
ATE421962T1 (de) | 2009-02-15 |
AR051626A1 (es) | 2007-01-24 |
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